Use tests: ROAT (repeated open application test)/PUT (provocative use test): an overview.

abstract：:The phenomenon of 'sensitive skin' is a relatively recent complaint in which certain individuals report more intense and frequent adverse sensory effects than the normal population upon use of cosmetic (personal-care) products. Originally defined as a minority complaint, sensitive skin is now claimed by a majority of ...

journal_title：Contact dermatitis

authors： Farage MA,Maibach HI

更新日期：2010-03-01 00:00:00

abstract：:To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'. ...

journal_title：Contact dermatitis

authors： Thyssen JP,Giménez-Arnau E,Lepoittevin JP,Menné T,Boman A,Schnuch A

更新日期：2012-04-01 00:00:00

abstract：:Results concerning 1,000 cases of contact dermatitis with positive patch tests are presented. The allergens which are responsible for about 50% of our cases are: turpentine, nickel, hexavalent chromium and organic mercurial compounds. These results are compared with those of other countries. As in the industrial world...

journal_title：Contact dermatitis

authors： Brun R

更新日期：1975-08-01 00:00:00

abstract：:The irritation potential of surfactants and body cleansing products was determined by evaluating the removal of dansyl chloride from the skin. Dilute solutions (2% active ingredient, w/v) of surfactants and soap extract fluorescence from the skin within 30 min. This is probably a physicochemical effect as it is too ra...

journal_title：Contact dermatitis

authors： Paye M,Simion FA,Pierard GE

更新日期：1994-02-01 00:00:00

abstract：:Contact sensitivity to 4 polyamines present in technical grade triethylenetetramine was investigated using the 'VAA mouse' assay and the guinea pig maximization test (GPMT). The criteria used to assess sensitivity in the GPMT classed all substances as having the same degree of sensitising potential. The mouse assay ra...

journal_title：Contact dermatitis

authors： Maisey J,Purchase R,Robbins MC,Miller K

更新日期：1988-03-01 00:00:00

abstract：:The arylpropionic acid derivatives (APADs) ketoprofen and tiaprofenic acid can provoke photoallergic dermatitis. Possible cross-reactivity between APADs is of importance in patients using nonsteroidal anti-inflammatory drugs. Because of the similarities in chemical structures, we investigated patients with photoallerg...

journal_title：Contact dermatitis

authors： Le Coz CJ,Bottlaender A,Scrivener JN,Santinelli F,Cribier BJ,Heid E,Grosshans EM

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Primin is the main contact allergen found in the ornamental plant Primula obconica Hance. OBJECTIVE:To analyse the temporal trend of sensitivity to primin in north-eastern Italy and to evaluate the associations with occupations in our geographical area. METHODOLOGY:From 1996 to 2012, 24 052 consecutive pat...

journal_title：Contact dermatitis

authors： Bongiorni L,Prodi A,Rui F,Belloni Fortina A,Corradin MT,Larese Filon F

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Cobalt release from dental prostheses has been shown to elicit allergic reactions in cobalt-allergic patients. It is therefore important to investigate whether these prostheses are possible sources of sensitization. OBJECTIVES:To assess (i) cobalt release from dental prostheses and (ii) allergic reactions t...

journal_title：Contact dermatitis

authors： Al-Imam H,Benetti AR,Özhayat EB,Pedersen AM,Johansen JD,Thyssen JP,Jellesen MS,Gotfredsen K

更新日期：2016-12-01 00:00:00

abstract：:For more than 50 years, the Draize rabbit skin irritation test has reigned supreme as the regulatory method of choice for the identification of skin irritant chemicals. To date no in vitro alternative test has been validated as an adequate replacement. However, one potential option, to test the endpoint of concern (sk...

journal_title：Contact dermatitis

authors： Robinson MK,McFadden JP,Basketter DA

更新日期：2001-07-01 00:00:00

abstract：:118 consecutive patients were photopatch tested with 5J UVA and 10mJ UVB. In addition, day 7 readings were taken. Testing with UVB and performing late readings conferred no advantage. The current recommendations of the British Photodermatology Group regarding photopatch testing remain the most recent guide to photopat...

journal_title：Contact dermatitis

authors： Pollock B,Wilkinson SM

更新日期：2001-05-01 00:00:00

abstract：:Chronic irritant contact dermatitis (ICD) is one of the most pressing problems in occupational medicine and is common in the food processing industry. To date, protective creams that fulfil the special requirements in the foodstuffs industry have not been available. Therefore, we studied the efficacy of pre-exposure a...

journal_title：Contact dermatitis

authors： Schliemann-Willers S,Wigger-Alberti W,Kleesz P,Grieshaber R,Elsner P

更新日期：2002-01-01 00:00:00

abstract：:The expression of surface-bound immunoglobulin E by dendritic cells within cutaneous tissue has been compared in atopic and contact dermatitis. 45 patients were recruited into 4 groups using clinical criteria and patch testing to a standard series of allergens: atopic (12 cases), allergic contact dermatitis (14 cases)...

journal_title：Contact dermatitis

authors： Ward KA,Todd D,Thornton C,Walsh M,Burrows D

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Contact allergy is frequent among persons with hand eczema and may be associated with a poor prognosis. OBJECTIVES:To identify allergens associated with the most severe initial clinical symptoms and the worst prognosis in a cohort of hand eczema patients followed for 6 months. METHODS:The study population ...

journal_title：Contact dermatitis

authors： Hald M,Agner T,Blands J,Ravn H,Johansen JD

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Cyclic acid anhydrides often cause allergic respiratory diseases, but contact urticaria because of these anhydrides has been considered rare. OBJECTIVE:We describe 21 patients diagnosed with occupational contact urticaria at the Finnish Institute of Occupational Health during the period 1990-2006. METHOD:P...

journal_title：Contact dermatitis

authors： Helaskoski E,Kuuliala O,Aalto-Korte K

更新日期：2009-04-01 00:00:00

abstract：:The literature is reviewed for contact dermatitis associated with transdermal therapeutic systems. Clonidine, nitroglycerin, scopolamine, estradiol and testosterone are utilized in such applications, and fentanyl is under investigation. Most cutaneous reactions are limited to localized dermatitis; however, generalized...

journal_title：Contact dermatitis

authors： Holdiness MR

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Patch tests help to confirm the aetiology of the cutaneous adverse drug reactions involving delayed hypersensitivity mechanisms, but the results vary with the pattern of skin reaction and the culprit drug. OBJECTIVES:To analyse the results of patch tests in patients with cutaneous adverse drug reactions imp...

journal_title：Contact dermatitis

authors： Pereira N,Canelas MM,Santiago F,Brites MM,Gonçalo M

更新日期：2011-10-01 00:00:00

abstract：:From 1985 to 1989, 13 cases of contact allergy to olive oil have been identified in the Departments of Dermatology of Kristianstad and Ostersund Hospitals. Known components of olive oil could not be proved to be the cause of the allergy. This high number of patients with contact allergy to olive oil and possible expla...

journal_title：Contact dermatitis

authors： Malmkvist Padoan S,Pettersson A,Svensson A

更新日期：1990-08-01 00:00:00

abstract：:Thiourea compounds are mainly used as accelerators in the rubber industry, but also in other industries, e.g., as antioxidants in the graphics industry. Thiourea compounds may provoke allergic contact dermatitis, although the number of reported cases is relatively low. During 1985-1991, we had 5 patients with allergic...

journal_title：Contact dermatitis

authors： Kanerva L,Estlander T,Jolanki R

更新日期：1994-10-01 00:00:00

abstract：:Deodorized kerosene in a concentration of 50 g/100 g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The respon...

journal_title：Contact dermatitis

authors： Nethercott JR,Lawrence M

更新日期：1983-11-01 00:00:00

abstract：:Between 1995 and 1999, 1986 patients were tested in the 31 participating centres of the Information Network of Departments of Dermatology (IVDK), all of them members of the German Contact Dermatitis Research Group, with a textile dyes series containing Disperse Blue (DB) 106 and 124, and since 1997 also with a mix of ...

journal_title：Contact dermatitis

authors： Uter W,Geier J,Lessmann H,Hausen BM,IVDK and the German Contact Dermatitis Research Grooup. Information Network of Departments of Dermatology.

更新日期：2001-03-01 00:00:00

abstract：:Allergic contact dermatitis caused by medical devices for diabetes patients has been increasingly described in the literature in the last few years. This article reviews the cases of allergic contact dermatitis caused by insulin pumps and glucose sensors reported since the 1970s, the culprit allergen(s), the results o...

journal_title：Contact dermatitis

authors： Herman A,de Montjoye L,Tromme I,Goossens A,Baeck M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The evidence on the safety of topical preparations containing botanical extracts is limited. OBJECTIVES:To assess (i) the use of botanically derived compounds in a large population, (ii) the incidence of cutaneous side-effects, and (iii) the diagnostic usefulness of patch testing. METHODS:A questionnaire w...

journal_title：Contact dermatitis

authors： Corazza M,Borghi A,Gallo R,Schena D,Pigatto P,Lauriola MM,Guarneri F,Stingeni L,Vincenzi C,Foti C,Virgili A

更新日期：2014-02-01 00:00:00

abstract：:In a retrospective study on selected group of patients, the coincidence of birch pollen allergy and a clinically relevant positive prick test reaction to apples and potatoes was confirmed. Immunochemical comparison using the crossed line immunoelectrophoresis technique (CLIE) confirmed partial identity between birch p...

journal_title：Contact dermatitis

authors： Andersen KE,Løwenstein H

更新日期：1978-04-01 00:00:00

abstract：:Investigations on light reactions in a patient with vitiligo are presented. The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins...

journal_title：Contact dermatitis

authors： Kavli G,Midelfart K,Raa J,Volden G

更新日期：1983-09-01 00:00:00

abstract：:In 23/135 (18%) workers exposed to epoxy resins, a work-related dermatosis on the hands and/or forearms had been present during the past 3 years. In 9 persons, the occupational dermatosis was still present at the time of investigation. In all workers, patch tests were performed with epoxy resin, isophoronediamine, tri...

journal_title：Contact dermatitis

authors： van Putten PB,Coenraads PJ,Nater JP

更新日期：1984-03-01 00:00:00

abstract：:A comparison was made between the guinea pig maximization test (GPMT), open epicutaneous test (OET) and chamber test (CT), and the allergens were neomycin sulphate and propylene glycol (PG). The sensitization rate for neomycin in petrolatum was 35% in GPMT, 25% in OET and 25% in CT. The corresponding figures for neomy...

journal_title：Contact dermatitis

authors： Kero M,Hannuksela M

更新日期：1980-08-01 00:00:00

abstract：:Exaggerated test conditions were frequently used to investigate the cutaneous tolerance of detergent products in the past. As the sensitivity of newly designed biometric methods is steadily improving, the trend towards more realistic test conditions should be encouraged. A hand immersion test under laboratory-controll...

journal_title：Contact dermatitis

authors： Paye M,Gomes G,Zerweck CR,Piérard GE,Grove GL

更新日期：1999-03-01 00:00:00

abstract：:In some patients with atopic dermatitis (AD), delayed-type allergy to aeroallergens, such as house dust mite, can be demonstrated by patch testing. Positive patch tests can be expected only in patients with AD and, in them, only to aeroallergens to which type 1 reactions have also been demonstrated. In an as yet unkno...

journal_title：Contact dermatitis

authors： de Groot AC,Young E

更新日期：1989-10-01 00:00:00

abstract：:This report reviews how to set up a laser Doppler perfusion imaging system intended for visualization of skin blood perfusion, capture images and evaluate the results obtained. A brief summary of related papers published in the literature within the areas of skin irritant and allergy patch testing, microdialysis and s...

journal_title：Contact dermatitis

authors： Fullerton A,Stücker M,Wilhelm KP,Wårdell K,Anderson C,Fischer T,Nilsson GE,Serup J,European Society of Contact Dermatitis Standardization Group.

更新日期：2002-03-01 00:00:00

abstract：:Patch testing with chemical irritants almost always produces a striking variability in the intensity of reaction between individuals, even amongst normal, healthy subjects. Whilst there have been many attempts to define factors which predispose to heightened or, conversely, to diminished reactivity, the underlying cel...

journal_title：Contact dermatitis

authors： Willis CM

更新日期：2002-11-01 00:00:00