Abstract：
BACKGROUND:Cyclic acid anhydrides often cause allergic respiratory diseases, but contact urticaria because of these anhydrides has been considered rare. OBJECTIVE:We describe 21 patients diagnosed with occupational contact urticaria at the Finnish Institute of Occupational Health during the period 1990-2006. METHOD:Prick test with human serum albumin (HSA)-acid anhydride conjugates, determination of specific immunoglobulin E (IgE), and open application were used in the diagnosis. RESULTS:The majority of the patients worked in the manufacture of electrical machines and were exposed to an epoxy hardener containing methyl hexahydrophthalic anhydride. The largest prick test reaction was often noted for the acid anhydride the patient had been exposed to. The specific IgE results were mostly in line with the prick test reactions. Phthalic anhydride IgE was determined in 20 patients and was found positive in 19 patients. In open application, a positive test result often required the use of the undiluted hardener. CONCLUSIONS:Contact urticaria may be more common than previously believed. Prick tests with HSA-acid anhydride conjugates were a useful test method for detecting immediate sensitization to acid anhydrides. The determination of the specific IgE gave almost equal results. The open application test often had to be performed with the undiluted anhydride product to obtain a positive test result.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Helaskoski E,Kuuliala O,Aalto-Korte Kdoi
10.1111/j.1600-0536.2009.01526.xsubject
Has Abstractpub_date
2009-04-01 00:00:00pages
214-21issue
4eissn
0105-1873issn
1600-0536pii
COD1526journal_volume
60pub_type
杂志文章abstract：:In four patients suffering from allergic contact eczema, the risk of sensitization to a new residue-leaving fungicide (Plondrel) used in spraying roses is considered. Two patients, however, were probably also sensitized to materials from the roses themselves. By gas-liquid chromatography the amount of the fungicide, e...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1975.tb05441.x
更新日期：1975-10-01 00:00:00
abstract：:Thirty-six of 37 veterinary surgeons with incapacitating dermatitis had allergic contact dermatitis, mainly from antibiotics such as spiramycin, Penethamate BP and tylosin. Eight were sensitive to rubber materials. Twenty of 36 had positive prick or scratch tests, mainly to animal hair. The atopic sensitivities were r...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1980.tb03885.x
更新日期：1980-01-01 00:00:00
abstract：:Sixteen patients with verified light sensitivity to both UVB and UVA wavebands showed allergic reactions to various lichen plants (Parmelia spp., Hypogymnia spp., Pseuodovernia spp., Cladonia spp., Platismatia spp., Physcia spp., Umbilicaria spp. and Cetraria spp.). Among the aromatic lichen compounds, atranorin was o...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1980.tb03911.x
更新日期：1980-01-01 00:00:00
abstract：:Repeated open application tests (ROATs) were performed with common ingredients of vehicles in 86 patients with contact dermatitis. The substances were applied twice daily for 7 days to the flexor aspect of the forearm near the cubital fossa, unless dermatitis appeared earlier. Of the patients with a questionable (?+) ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1986.tb01229.x
更新日期：1986-04-01 00:00:00
abstract：BACKGROUND:Contact allergy to dental materials is poorly understood; clinical manifestations are heterogeneous. OBJECTIVE:To analyse positive patch test reactions to metals (as their alloys or salts) used in dentistry together with clinical symptoms and possible relevance to dental fillings. METHODS:We retrospectivel...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2009.01524.x
更新日期：2009-06-01 00:00:00
abstract：:Patch testing, using European standard allergens and suspected causative substances brought in by patients, was carried out in 490 patients with eczema in Hong Kong and 437 completed the test. Before patch testing, 244, 141 and 105 patients were diagnosed as having contact dermatitis, endogenous eczema and unclassifie...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1996.tb02261.x
更新日期：1996-07-01 00:00:00
abstract：:Surgical rubber gloves contain allergens derived from natural rubber latex which may sensitize, causing contact urticaria and even systemic reactions. We examined 15 hospital employees allergic to latex surgical gloves, using various skin tests and RAST, to determine the most reliable diagnostic method and to investig...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1988.tb02920.x
更新日期：1988-10-01 00:00:00
abstract：:Between 1995 and 1999, 1986 patients were tested in the 31 participating centres of the Information Network of Departments of Dermatology (IVDK), all of them members of the German Contact Dermatitis Research Group, with a textile dyes series containing Disperse Blue (DB) 106 and 124, and since 1997 also with a mix of ...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究
doi：10.1034/j.1600-0536.2001.044003173.x
更新日期：2001-03-01 00:00:00
abstract：:Contact allergy to corticosteroids now seems frequent among patients being patch tested. As corticosteroids are intrinsically anti-inflammatory, we investigated whether patch tests with a potent corticosteroid might suppress simultaneous adjacent patch test reactions to another allergen. Nickel-sensitive subjects were...
journal_title：Contact dermatitis
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0536.1995.tb00809.x
更新日期：1995-03-01 00:00:00
abstract：:A 30-year-old male developed asthma and pruritus after using an insecticidal spray (Pyrex). The same symptoms appeared with an alcoholic skin disinfectant (M-sprit) and other spirituous preparations denaturated with denatonium benzoate (Bitrex). An open epicutaneous test (20 min) showed wheal and erythema to Pyrex, M-...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1980.tb05568.x
更新日期：1980-12-01 00:00:00
abstract：:To test the screening value of the sesquiterpene lactone (SL) mix in Europe today and describe epidemiological and clinical features of Compositae-sensitive patients, the SL mix 0.1% pet. was included in the standard patch test series in 11 European clinics. 10,695 patients were tested, and 106 (1%) had positive react...
journal_title：Contact dermatitis
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1111/j.1600-0536.1999.tb05994.x
更新日期：1999-02-01 00:00:00
abstract：:202 patients, 68 males and 134 females, with patch-test-negative, symmetrical vesicular hand eczema were challenged orally in a controlled study with 2.5 mg nickel, 2.5 mg chromium and 1 mg cobalt given as salts of the respective metals. Initially a mixture of the 3 metal salts was given, and if this produced a flare ...
journal_title：Contact dermatitis
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-0536.1983.tb04437.x
更新日期：1983-09-01 00:00:00
abstract：:This report reviews individual-related variables, environment-related variables and instrument-related variables, with a focus on the Evaporimeter EP1 (ServoMed). Start-up and use is described, and guidelines for good laboratory practice given. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1990.tb01553.x
更新日期：1990-03-01 00:00:00
abstract：:The local lymph node assay (LLNA) is used for assessing sensitizing potential in hazard identification and risk assessment for regulatory purposes. Sensitizing potency on the basis of the LLNA is categorized into extreme (EC3 value of ≤0.2%), strong (>0.2% to ≤2%), and moderate (>2%). To compare the sensitizing potenc...
journal_title：Contact dermatitis
pub_type： 杂志文章,评审
doi：10.1111/cod.12683
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Hand eczema is common in the nursing profession, and has been reported widely in various parts of the world. OBJECTIVES:The aim of this study was to determine the prevalence and severity of hand eczema among nurses working in a regional hospital in Hong Kong, as well as its psychosocial impact and any possi...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2011.01961.x
更新日期：2011-12-01 00:00:00
abstract：:As one step in defining the clinical relevance of exposure to an allergen identified with patch testing, use tests (provocative use test (PUT), and repeated open application test (ROAT)) have been used. In 1/2 of the cases of seemingly reliable patch tests, use tests are negative, suggesting that the patient's biologi...
journal_title：Contact dermatitis
pub_type： 杂志文章,评审
doi：10.1034/j.1600-0536.2000.043001001.x
更新日期：2000-07-01 00:00:00
abstract：:A chemical operator handling dimethyl acetylenedicarboxylate (DMAD) developed delayed and pain-free burns on one of his feet 2 days after a supposed spillage of DMAD. The injuries were confirmed to be associated with DMAD by chemical analysis of the operator's safety boot and patch tests. DMAD easily penetrates some p...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1984.tb00166.x
更新日期：1984-07-01 00:00:00
abstract：BACKGROUND:There are no Indian studies on the association between filaggrin gene (FLG) mutations and any dermatosis, including hand eczema. OBJECTIVES:To determine the prevalence of FLG mutations in Indian hand eczema patients, and examine associations between such mutations and any aetiological type of hand eczema. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.13233
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:The prevalence of p-phenylenediamine (PPD) sensitization is 4% in the patch tested population and varies between zero and 1.5% in the general population. Hair dye is a recognised sensitization source. OBJECTIVES:To define the prevalence rates of PPD sensitization in the general and patch tested populations ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.12354
更新日期：2015-06-01 00:00:00
abstract：:In our Department, the incidence of sensitization to cobalt has more than doubled in the last 5 years. 28% of cobalt-sensitive patients showed no other sensitivity. Of isolated cobalt sensitive patients, 68% were housewives. We determined by atomic absorption spectrophotometry with a graphite camera, the cobalt and ni...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1987.tb01407.x
更新日期：1987-03-01 00:00:00
abstract：BACKGROUND:Protein contact dermatitis is a frequent disorder among hand eczema patients who have occupational food contact. Knowledge about the consequences of having protein contact dermatitis is lacking. OBJECTIVES:To investigate the consequences of having occupational skin disease on the hands resulting from food h...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2012.02101.x
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Lavender is commonly used in aromatherapy and in a broad range of personal and household products. It has been identified as a contact sensitizer, and has been reported to cause allergic contact dermatitis (ACD). OBJECTIVES:To report our experience with contact allergy and ACD caused by lavender, and to rai...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.13247
更新日期：2019-07-01 00:00:00
abstract：:An outbreak of occupational dermatitis in a rubber tyre factory is reported. An unusual clinical picture was recognized. Patch tests revealed a high sensitization rate to the MBT derivative used: 2-(2'-4'dinitrophenylthio)benzothiazole. Since tests with MBT mix and dinitrophenol were negative; sensitization to a conta...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1987.tb02637.x
更新日期：1987-07-01 00:00:00
abstract：:A healed or healing allergic contact dermatitis is easily reactivated to a flare-up if the patient is provoked systemically with his particular allergen. 5 patients with contact allergy to gold were patch tested with a serial dilution of gold sodium thiosulfate. 1 to 2 months later, when positive test reactions were h...
journal_title：Contact dermatitis
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0536.1999.tb06103.x
更新日期：1999-09-01 00:00:00
abstract：:Deodorized kerosene in a concentration of 50 g/100 g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The respon...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1983.tb04459.x
更新日期：1983-11-01 00:00:00
abstract：BACKGROUND:While allergy to food proteins is almost exclusively found in association with atopy, it has been our experience that contact allergy to some contact allergens/haptens with both cutaneous and gastrointestinal exposures is reduced in atopic dermatitis (AD) patients as a group. OBJECTIVE:To assess the contact...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2008.01321.x
更新日期：2008-05-01 00:00:00
abstract：:In some patients with atopic dermatitis (AD), delayed-type allergy to aeroallergens, such as house dust mite, can be demonstrated by patch testing. Positive patch tests can be expected only in patients with AD and, in them, only to aeroallergens to which type 1 reactions have also been demonstrated. In an as yet unkno...
journal_title：Contact dermatitis
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0536.1989.tb03197.x
更新日期：1989-10-01 00:00:00
abstract：:Protein kinase C (PKC) isoforms are important in cell signal transduction associated with regulation of cell proliferation and differentiation. In this study, alterations of PKC isoform levels in irritant patch test reactions were detected by Western immunoblots. 4 chemically and structurally different irritants, 4% a...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1998.tb05766.x
更新日期：1998-06-01 00:00:00
abstract：:Diglycidyl ether of bisphenol A (DGEBA) is the monomer and most important contact allergen in epoxy resin(s) based on bisphenol A (DGEBA-R). Both thin-layer chromatography (TLC) and high-pressure liquid chromatography (HPLC) methods are available for the analysis of products containing DGEBA-R. With respect to detecti...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.0105-1873.2004.00319.x
更新日期：2004-05-01 00:00:00
abstract：:Kojic acid (5-hydroxy-2-(hydroxymethyl)-4-pyrone), a fungal metabolic product, has increasingly been used as a skin-depigmenting agent in skin care products marketed in Japan since 1988. In order to determine its frequency of sensitization, during 1 year from October 1992 to September 1993, we performed patch testing ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1995.tb00832.x
更新日期：1995-01-01 00:00:00
