Abstract：
:Kojic acid (5-hydroxy-2-(hydroxymethyl)-4-pyrone), a fungal metabolic product, has increasingly been used as a skin-depigmenting agent in skin care products marketed in Japan since 1988. In order to determine its frequency of sensitization, during 1 year from October 1992 to September 1993, we performed patch testing with it in 220 female patients with suspected cosmetic-related contact dermatitis. Of the 220 patients, 8 used at least 1 skin care product containing kojic acid, 5 of whom reacted to kojic acid as well as to 1 or more their own products containing 1% kojic acid, but not to their other products not containing it, and 3 of whom were negative to kojic acid and all their own products. Patch testing with kojic acid in the remaining group of 212 patients, who had not previously used skin care products containing it, was negative without exception. The 5 kojic-acid-sensitive patients, aged 34 to 58 years, developed facial dermatitis 1-12 months after starting application of kojic-acid-containing products. Kojic acid is considered to have high sensitizing potential, as a comparatively high frequency of contact sensitivity was observed in patients using products containing it (5 out of 8).
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Nakagawa M,Kawai K,Kawai Kdoi
10.1111/j.1600-0536.1995.tb00832.xsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
9-13issue
1eissn
0105-1873issn
1600-0536journal_volume
32pub_type
杂志文章abstract：:Quercetin is a bioflavonoid with antioxidant and anti-inflammatory activity. The purpose of this study was to examine the effect of quercetin on acute skin irritation, with special interest in the skin barrier function recovery. Acute irritant contact dermatitis was induced in 15 patients by 24-h occlusion of 2% sodiu...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2000.042002085.x
更新日期：2000-02-01 00:00:00
abstract：:Whilst patch testing with corticosteroids in ethanol is more sensitive than either petrolatum or the cream formulation, the frequency of false-negative reactions is not known. We have compared patch testing with corticosteroid at 1% in ethanol with intradermal (i.d.) tests using 1 mg corticosteroid suspended in normal...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1997.tb00393.x
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series. OBJECTIVES:To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a ...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究
doi：10.1111/j.1600-0536.2011.01921.x
更新日期：2011-07-01 00:00:00
abstract：:Patch testing is an invaluable tool for the experimental induction of acute irritant contact dermatitis (ICD), with a variety of chamber systems available for use. Ideally, the inflammatory reactions produced should be of uniform intensity across the test area, thereby facilitating grading of the response and tissue s...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1999.tb06158.x
更新日期：1999-11-01 00:00:00
abstract：:We report a case of hypertrophic allergic contact dermatitis probably due to p-phenylenediamine (PPDA) in a 26-year-old female, which developed at the sites of application of a black hair dye to the skin. Histological examination revealed an eczematous process. The lesions subsided completely except for leukoderma tha...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1994.tb01958.x
更新日期：1994-09-01 00:00:00
abstract：:The occurrence and causes of occupational dermatoses at a film laboratory following modernization was studied. In 1983 the film laboratory moved to new premises built to reduce exposure to hazardous chemicals. The study was carried out during 1983-1986 with repeated interviews and dermatological examinations of all em...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1989.tb04656.x
更新日期：1989-03-01 00:00:00
abstract：:According to some reports in the literature, the hormonal fluctuations which occur during the menstrual cycle may affect the clinical expression of contact allergy to a greater or lesser degree. In clinical practice, too, patient history often shows exacerbation of the contact dermatitis during the days immediately pr...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.0105-1873.2005.00588.x
更新日期：2005-06-01 00:00:00
abstract：BACKGROUND:Primin is the main contact allergen found in the ornamental plant Primula obconica Hance. OBJECTIVE:To analyse the temporal trend of sensitivity to primin in north-eastern Italy and to evaluate the associations with occupations in our geographical area. METHODOLOGY:From 1996 to 2012, 24 052 consecutive pat...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.12385
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:The evidence on the safety of topical preparations containing botanical extracts is limited. OBJECTIVES:To assess (i) the use of botanically derived compounds in a large population, (ii) the incidence of cutaneous side-effects, and (iii) the diagnostic usefulness of patch testing. METHODS:A questionnaire w...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究
doi：10.1111/cod.12124
更新日期：2014-02-01 00:00:00
abstract：:The Danish Twin Register represents a population-based twin sample where the twins enter the Register independently of disease. All female twins born between 1906-30 and available in the Register in January 1978 were sent a questionnaire concerning possible nickel sensitivity. Among 746 pairs living in the eastern par...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1983.tb04393.x
更新日期：1983-07-01 00:00:00
abstract：:This report reviews how to set up a laser Doppler perfusion imaging system intended for visualization of skin blood perfusion, capture images and evaluate the results obtained. A brief summary of related papers published in the literature within the areas of skin irritant and allergy patch testing, microdialysis and s...
journal_title：Contact dermatitis
pub_type： 指南,杂志文章,实务指引,评审
doi：10.1034/j.1600-0536.2002.460301.x
更新日期：2002-03-01 00:00:00
abstract：:It has been known since the 1940s that nail polishes contain allergenic ingredients. The aim of this study was to clarify whether the nail polishes on the market today contain significant amounts of allergens, and what the solvents are. The following ingredients were determined: toluene, toluene sulfonamide formaldehy...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1997.tb00189.x
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND:Amines in epoxy hardeners are significant causes of occupational allergic contact dermatitis among workers who use epoxy resin systems. OBJECTIVES:To describe a novel group of contact allergens: N-(2-phenylethyl) derivatives of the reactive amine 1,3-benzenedimethanamine (1,3-BDMA). METHODS:We describe the...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.12652
更新日期：2016-12-01 00:00:00
abstract：:An outbreak of occupational dermatitis in a rubber tyre factory is reported. An unusual clinical picture was recognized. Patch tests revealed a high sensitization rate to the MBT derivative used: 2-(2'-4'dinitrophenylthio)benzothiazole. Since tests with MBT mix and dinitrophenol were negative; sensitization to a conta...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1987.tb02637.x
更新日期：1987-07-01 00:00:00
abstract：:Allergic contact dermatitis is reported in a patient using a condom with the spermicidal lubricant Tectol. A 36 year old female, with no history of dermatitis or pruritus of the vagina or vulva, experienced itchy dermatitis 24-48 hours after her partner used a Durex Top Safe contraceptive containing Tectol. The derm...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1987.tb02678.x
更新日期：1987-08-01 00:00:00
abstract：BACKGROUND:Occlusion of the skin is a risk factor for development of irritant contact dermatitis. Occlusion may, however, have a positive effect on skin healing. No consensus on the effect of occlusion has been reached. OBJECTIVES:To investigate skin barrier response to occlusion on intact and damaged skin. METHODS:I...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2010.01773.x
更新日期：2010-12-01 00:00:00
abstract：:Plants from the Verbenaceae family may cause contact dermatitis of unknown nature. This report describes 2 cases of allergic reactions to the Verbena species. A teenage boy developed an anaphylactic allergic response following contact with the leaves of Verbena hybrida. Characterization of the patient's specific IgE r...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1995.tb02049.x
更新日期：1995-11-01 00:00:00
abstract：:A chemical operator handling dimethyl acetylenedicarboxylate (DMAD) developed delayed and pain-free burns on one of his feet 2 days after a supposed spillage of DMAD. The injuries were confirmed to be associated with DMAD by chemical analysis of the operator's safety boot and patch tests. DMAD easily penetrates some p...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1984.tb00166.x
更新日期：1984-07-01 00:00:00
abstract：:3-Iodo-2-propynyl-butylcarbamate (IPBC) is a fungicide used in both industrial products and cosmetics. We report the first case of allergic contact dermatitis from airborne exposure to this preservative. A 34-year-old female production worker at a paint factory developed dermatitis on air-exposed skin areas. Patch tes...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2003.00079.x
更新日期：2003-03-01 00:00:00
abstract：:Cyclosporine (CSA) is an effective immunosuppressive agent and is used in tissue transplantation. The present investigation was undertaken to determine the effect of topical delivery of CSA on allergic contact dermatitis in guinea pigs. Topical 15% CSA in an azone (1-dodecylazacycloheptan-2-one)-containing vehicle blo...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1989.tb03088.x
更新日期：1989-01-01 00:00:00
abstract：:230 patients with occupational dermatitis in the metallurgic industry were studied with standard patch test (GEIDC) and an oil series. An occupational and clinical questionnaire survey was carried out. Responses to paraphenylenediamine, chrome, cobalt in the standard series, and benzisothiazolone, triethanolamine, and...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1985.tb01081.x
更新日期：1985-03-01 00:00:00
abstract：BACKGROUND:Contact allergy to dental materials is poorly understood; clinical manifestations are heterogeneous. OBJECTIVE:To analyse positive patch test reactions to metals (as their alloys or salts) used in dentistry together with clinical symptoms and possible relevance to dental fillings. METHODS:We retrospectivel...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2009.01524.x
更新日期：2009-06-01 00:00:00
abstract：:A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1979.tb04860.x
更新日期：1979-07-01 00:00:00
abstract：:The goal of this study was to evaluate biophysically and clinically the hand skin of nurses working in the operating room in comparison with the hand skin of a control group of female administrative employees. 19 nurses and 14 employees were included in this trial. Transepidermal water loss (TEWL) and stratum corneum ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2002.460406.x
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:Panthenol (synonym: dexpanthenol), the alcohol analogue of panthothenic acid, is frequently included in moisturizers, wound-healing agents, and other cosmetics, and has been shown to be responsible for allergic contact dermatitis (ACD). OBJECTIVES:To evaluate the frequency of ACD caused by dexpanthenol, and...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.13054
更新日期：2018-11-01 00:00:00
abstract：:A tire assembler developed contact dermatitis from IPPD, a rubber antioxidant. The lichenoid clinical pattern corresponded histologically to lichenified dermatitis. Tire assemblers appear to acquire contact dermatitis to this aromatic amine more frequently than any other workers in the tire manufacturing industry. Pos...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1982.tb04152.x
更新日期：1982-03-01 00:00:00
abstract：:In order to explain the complaints of dry skin after work among employees in the fish processing industry, we followed the skin blood flow (SBF), skin surface temperature, transepidermal water loss (TEWL) and electrical capacitance on the volar aspect of the 3rd finger in 10 fillet workers, where measurements were per...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1991.tb01767.x
更新日期：1991-07-01 00:00:00
abstract：:Allergens used for patch testing in the hairdressing series vary between dermatology centres in the UK. The aim of our study is to ascertain the hairdressing allergens currently in use and their test results in several dermatology centres in the UK. Data were obtained from databases in 9 dermatology departments. The a...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究
doi：10.1111/j.0105-1873.2005.00661.x
更新日期：2005-09-01 00:00:00
abstract：:Effects of test techniques on neomycin patch test results have not been thoroughly investigated. This study focuses on effects of dose and application time of neomycin sulfate patch tests on test results. The effects are assessed both visually and by perfusion. 16 subjects positive to neomycin are retested with neomyc...
journal_title：Contact dermatitis
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1600-0536.2000.043005283.x
更新日期：2000-11-01 00:00:00
abstract：:The dose- and time-related effect of sodium lauryl sulfate (SLS) on in vitro percutaneous penetration was studied using 3 radiolabeled tracer compounds with different physicochemical properties: tritiated water, hydrocortisone and nickel. Human cadaver abdominal skin from caucasian women was used as membrane in static...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1995.tb00622.x
更新日期：1995-06-01 00:00:00
