Evaluation of biophysical and clinical parameters of skin barrier function among hospital workers.

Abstract:

:The goal of this study was to evaluate biophysically and clinically the hand skin of nurses working in the operating room in comparison with the hand skin of a control group of female administrative employees. 19 nurses and 14 employees were included in this trial. Transepidermal water loss (TEWL) and stratum corneum (SC) hydration were evaluated on 4 different test sites - dominant and non-dominant pulse, and dominant and non-dominant hand dorsum. The clinical score Dermatology Life Quality Index (DLQI) and subjective evaluation of skin sensitivity were also recorded. In comparison with the control group, TEWL values among nurses were significantly higher on all test sites, while SC hydration was significantly lower on 3 of the 4 test sites. In addition, clinical score showed the presence of irritant contact dermatitis (ICD). DLQI reported a higher level of disability among the nurses group, while the subjective evaluation of skin sensitivity was identical in both groups. The results suggest the presence of skin barrier alterations and clinical signs of chronic ICD on the hands of nurses working in operating room units.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Hachem JP,De Paepe K,Sterckx G,Kaufman L,Rogiers V,Roseeuw D

doi

10.1034/j.1600-0536.2002.460406.x

keywords:

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

220-3

issue

4

eissn

0105-1873

issn

1600-0536

pii

cod460406

journal_volume

46

pub_type

杂志文章
  • The role of contact allergy to aeroallergens in atopic dermatitis.

    abstract::In some patients with atopic dermatitis (AD), delayed-type allergy to aeroallergens, such as house dust mite, can be demonstrated by patch testing. Positive patch tests can be expected only in patients with AD and, in them, only to aeroallergens to which type 1 reactions have also been demonstrated. In an as yet unkno...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.1989.tb03197.x

    authors: de Groot AC,Young E

    更新日期:1989-10-01 00:00:00

  • Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses: part II of a prospective cohort study.

    abstract:BACKGROUND/OBJECTIVES:Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet work exposure on the development of hand eczema in apprentice nurses....

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12139

    authors: Visser MJ,Verberk MM,Campbell LE,McLean WH,Calkoen F,Bakker JG,van Dijk FJ,Bos JD,Kezic S

    更新日期:2014-03-01 00:00:00

  • The development of metal hypersensitivity in patients with metal-to-plastic hip arthroplasties.

    abstract::Sixty-six patients who had to undergo total hip replacement by means of a metal-to-plastic Stanmore prosthesis, were patch-tested prior to and 6 to 12 months after surgery with the standard ICDRG all allergens series and with acrylic monomer 5% in acetone. In 62 patients the history of metal allergy as well as the pat...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1976.tb03044.x

    authors: Nater JP,Brain RG,Deutman R,Mulder TJ

    更新日期:1976-10-01 00:00:00

  • Photosensitivity and allergy to aromatic lichen acids, Compositae oleoresins and other plant substances.

    abstract::Sixteen patients with verified light sensitivity to both UVB and UVA wavebands showed allergic reactions to various lichen plants (Parmelia spp., Hypogymnia spp., Pseuodovernia spp., Cladonia spp., Platismatia spp., Physcia spp., Umbilicaria spp. and Cetraria spp.). Among the aromatic lichen compounds, atranorin was o...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1980.tb03911.x

    authors: Thune PO,Solberg YJ

    更新日期:1980-01-01 00:00:00

  • Sodium metabisulfite--a marker for cosmetic allergy?

    abstract::A 45-year-old woman developed dermatitis of the face after she applied a cosmetic package comprising day and night creams. Patch tests were performed with the British Contact Dermatitis Society (BCDS) standard, bases + preservatives, and cosmetic series in addition to samples of both creams and the individual constitu...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.00972.x

    authors: Malik MM,Hegarty MA,Bourke JF

    更新日期:2007-04-01 00:00:00

  • Contact allergenic activity of Tween 80 before and after air exposure.

    abstract::Tween 80 is an ethoxylated hydrophilic non-ionic surfactant, which is used for the preparation of oil-in-water emulsions in pharmaceutical products, cosmetics, and industrial detergents. Ethoxylated surfactants are polyethers and are thus easily oxidized by atmospheric oxygen to a variety of hydroperoxides, peroxides ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1997.tb00368.x

    authors: Bergh M,Magnusson K,Nilsson JL,Karlberg AT

    更新日期:1997-07-01 00:00:00

  • Allergy to lanolin.

    abstract::The purpose of the present study was to compare the frequency of lanolin allergy during two periods and to assess the adequacy of testing with one standard allergen. Among 1230 consecutive patients with eczema who were standard patch tested, 33 (2.7%), 21 females and 12 males, gave a positive reaction to wool alcohols...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04824.x

    authors: Mortensen T

    更新日期:1979-05-01 00:00:00

  • Antigen-presenting cells and keratinocytes express interleukin-12 in allergic contact dermatitis.

    abstract::Interleukin-12 (IL-12) has previously been suggested as playing a major rôle in the activation of cytotoxic lymphocytes. Recent reports indicate that cytotoxic CD8+ cells are critically involved in the elicitation phase of contact hypersensitivity reactions. In this study, the in situ expression of IL-12 was investiga...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2000.042001018.x

    authors: Yawalkar N,Egli F,Brand CU,Pichler WJ,Braathen LR

    更新日期:2000-01-01 00:00:00

  • Allergic contact dermatitis caused by dexpanthenol-Probably a frequent allergen.

    abstract:BACKGROUND:Panthenol (synonym: dexpanthenol), the alcohol analogue of panthothenic acid, is frequently included in moisturizers, wound-healing agents, and other cosmetics, and has been shown to be responsible for allergic contact dermatitis (ACD). OBJECTIVES:To evaluate the frequency of ACD caused by dexpanthenol, and...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13054

    authors: Fernandes RA,Santiago L,Gouveia M,Gonçalo M

    更新日期:2018-11-01 00:00:00

  • Guidelines for visualization of cutaneous blood flow by laser Doppler perfusion imaging. A report from the Standardization Group of the European Society of Contact Dermatitis based upon the HIRELADO European community project.

    abstract::This report reviews how to set up a laser Doppler perfusion imaging system intended for visualization of skin blood perfusion, capture images and evaluate the results obtained. A brief summary of related papers published in the literature within the areas of skin irritant and allergy patch testing, microdialysis and s...

    journal_title:Contact dermatitis

    pub_type: 指南,杂志文章,实务指引,评审

    doi:10.1034/j.1600-0536.2002.460301.x

    authors: Fullerton A,Stücker M,Wilhelm KP,Wårdell K,Anderson C,Fischer T,Nilsson GE,Serup J,European Society of Contact Dermatitis Standardization Group.

    更新日期:2002-03-01 00:00:00

  • Natural vegetable fats in the prevention of irritant contact dermatitis.

    abstract::Chronic irritant contact dermatitis (ICD) is one of the most pressing problems in occupational medicine and is common in the food processing industry. To date, protective creams that fulfil the special requirements in the foodstuffs industry have not been available. Therefore, we studied the efficacy of pre-exposure a...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0536.2002.460102.x

    authors: Schliemann-Willers S,Wigger-Alberti W,Kleesz P,Grieshaber R,Elsner P

    更新日期:2002-01-01 00:00:00

  • Outcome of a second patch test reading of TRUE Tests® on D6/7.

    abstract::Background. Two readings of patch test reactions are recommended. Objectives. To evaluate the outcome of a second patch test reading of TRUE Test® allergens on D6/7 in relation to negative or doubtful reactions on D3/4. Methods. This was a retrospective investigation of patch test data from January 1992 to October 201...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12004

    authors: Madsen JT,Andersen KE

    更新日期:2013-02-01 00:00:00

  • Occupational nickel dermatitis in the electroforming industry.

    abstract::An outbreak of occupational dermatitis in an electroforming plant where there was heavy exposure to nickel is described. Patch test investigations confirmed nickel allergy in 13 of 27 exposed individuals. Nickel chloride was found to be a more reliable patch test allergen than nickel sulphate. Improvements in industri...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1980.tb04985.x

    authors: Wall LM,Calnan CD

    更新日期:1980-10-01 00:00:00

  • A comparison of expression of surface-bound immunoglobulin E on antigen-presenting cells in cutaneous tissue between patients with allergic, irritant and atopic dermatitis.

    abstract::The expression of surface-bound immunoglobulin E by dendritic cells within cutaneous tissue has been compared in atopic and contact dermatitis. 45 patients were recruited into 4 groups using clinical criteria and patch testing to a standard series of allergens: atopic (12 cases), allergic contact dermatitis (14 cases)...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1991.tb01799.x

    authors: Ward KA,Todd D,Thornton C,Walsh M,Burrows D

    更新日期:1991-08-01 00:00:00

  • Allergic contact dermatitis caused by alkyl glucosides.

    abstract:BACKGROUND:Alkyl glucosides were not expected to have a sensitizing potential at the concentrations to be used in finished consumer products; however, several contact allergy cases have been published. OBJECTIVES:To report on the patients suffering from allergic contact dermatitis caused by alkyl glucosides observed i...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12154

    authors: Gijbels D,Timmermans A,Serrano P,Verreycken E,Goossens A

    更新日期:2014-03-01 00:00:00

  • Contact allergy to lanolin: temporal changes in prevalence and association with atopic dermatitis.

    abstract:BACKGROUND:Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases. OBJECTIVES:To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols and/or Amerchol™ L-101)...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12872

    authors: Fransen M,Overgaard LEK,Johansen JD,Thyssen JP

    更新日期:2018-01-01 00:00:00

  • Chemical analysis of monomers in epoxy resins based on bisphenols F and A.

    abstract::Diglycidyl ether of bisphenol A (DGEBA) is the monomer and most important contact allergen in epoxy resin(s) based on bisphenol A (DGEBA-R). Both thin-layer chromatography (TLC) and high-pressure liquid chromatography (HPLC) methods are available for the analysis of products containing DGEBA-R. With respect to detecti...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2004.00319.x

    authors: Pontén A,Zimerson E,Sörensen O,Bruze M

    更新日期:2004-05-01 00:00:00

  • Cross-reaction patterns in patients with contact allergy to simple methylol phenols.

    abstract::The low-molecular-weight phenols 2-methylol phenol (2-MP), 4-methylol phenol (4-MP), 2,4,6-trimethylol phenol (2,4,6-MP), 3-methylol phenol (3-MP), 2,4-dimethylol phenol (2,4-MP), and 2,6-dimethylol phenol (2,6-MP) are contact sensitizers in resins based on phenol and formaldehyde (P-F-R). Other chemically related low...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1997.tb00044.x

    authors: Bruze M,Zimerson E

    更新日期:1997-08-01 00:00:00

  • An overview of the efficacy of topical corticosteroids in experimental human nickel contact dermatitis.

    abstract::We review controlled trials of corticosteroid effect in experimentally elicited acute nickel contact dermatitis in man, in the hope of clarifying optimal efficacy for clinical use. To maximize discrimination and objectivity, we focus on data with 1 well-characterized allergen, nickel, in studies utilizing bioengineeri...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1034/j.1600-0536.2000.043006317.x

    authors: Levin C,Maibach HI

    更新日期:2000-12-01 00:00:00

  • Cobalt release and complications resulting from the use of dental prostheses.

    abstract:BACKGROUND:Cobalt release from dental prostheses has been shown to elicit allergic reactions in cobalt-allergic patients. It is therefore important to investigate whether these prostheses are possible sources of sensitization. OBJECTIVES:To assess (i) cobalt release from dental prostheses and (ii) allergic reactions t...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12649

    authors: Al-Imam H,Benetti AR,Özhayat EB,Pedersen AM,Johansen JD,Thyssen JP,Jellesen MS,Gotfredsen K

    更新日期:2016-12-01 00:00:00

  • Sensitization capacity of ethylenediamine in the guinea pig and induction of unresponsiveness.

    abstract::The sensitization capacity of ethylenediamine was examined by the guinea pig maximization test and compared with dinitrochlorobenzene. Ethylenediamine was found to be a potent sensitizer. An attempt at oral induction of unresponsiveness (tolerance) was unsuccessful with ethylenediamine and DNCB and the same negative r...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04881.x

    authors: Eriksen K

    更新日期:1979-09-01 00:00:00

  • Are opera-house artistes afflicted with contact allergy to colophony and cosmetics?

    abstract::The frequencies of cosmetics intolerance and contact allergy to colophony were investigated among 116 singers and dancers and 16 make-up artists. Participants were interviewed, examined and patch tested with a standard series and materials from the opera house. Common skin lesions were found in 1/3 of participants and...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1995.tb00780.x

    authors: Färm G,Karlberg AT,Lidén C

    更新日期:1995-05-01 00:00:00

  • Contact sensitivity to topical antimicrobials. (II). Sensitizing potentials of some topical antimicrobials.

    abstract::A predictive study comparing the sensitizing potentials of some topical antimicrobials, using a modified Beuhler's technique, showed that over-the-counter (OTC) antimicrobials were more sensitizing than prescribed topical antibiotics. Among OTC antimicrobials, proflavine was the most potent sensitizer (4/10 guinea pig...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1989.tb04730.x

    authors: Goh CL

    更新日期:1989-09-01 00:00:00

  • Nickel deposited on the skin-visualization by DMG test.

    abstract:BACKGROUND:Nickel is the most common cause of contact allergy and an important risk factor for hand eczema. Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel. OBJECTIVES:To develop and evaluate methods for visualization of ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2010.01856.x

    authors: Julander A,Skare L,Vahter M,Lidén C

    更新日期:2011-03-01 00:00:00

  • The effect of the guinea pig maximization protocol on the irritant response to deodorized kerosene - the excited skin syndrome.

    abstract::Deodorized kerosene in a concentration of 50 g/100 g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The respon...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1983.tb04459.x

    authors: Nethercott JR,Lawrence M

    更新日期:1983-11-01 00:00:00

  • Penetration and haptenation of p-phenylenediamine.

    abstract::Although p-phenylenediamine (PPD) has been recognized as an extreme sensitizer for many years, the exact mechanism of sensitization has not been elucidated yet. Penetration and the ability to bind to proteins are the first two hurdles that an allergen has to overcome to be able to sensitize. This review is an overview...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/cod.12032

    authors: Pot LM,Scheitza SM,Coenraads PJ,Blömeke B

    更新日期:2013-04-01 00:00:00

  • Occupational dermatoses in a metalworking plant.

    abstract::In a plant producing advanced components for engines and drivelines we undertook a survey of occupational dermatoses, based on a questionnaire, clinical examination, and patch testing with a standard series and a series of samples from the working environment. The questionnaire was given to all 430 employees and it wa...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2003.480205.x

    authors: Gruvberger B,Isaksson M,Frick M,Pontén A,Bruze M

    更新日期:2003-02-01 00:00:00

  • Evaluation of a quantitative clinical method for assessment of sensory skin irritation.

    abstract::Sensory skin irritation refers to the myriad of symptomatic complaints (e.g., sting and burn) frequently associated with inflammatory skin conditions or skin intolerance to various chemicals or finished products. Sensory irritation is an important factor in consumer acceptance of the products that they buy and use; ho...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0536.2001.450403.x

    authors: Robinson MK,Perkins MA

    更新日期:2001-10-01 00:00:00

  • UK rates of occupational skin disease attributed to rubber accelerators, 1996-2012.

    abstract:BACKGROUND:Natural and synthetic rubbers containing rubber accelerators are well-known causes of allergic contact dermatitis (ACD). Latex contact urticaria (CU) has been widely reported, especially when powdered latex glove use was commonplace. Consequently, interventions to reduce latex exposure by altering glove manu...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12356

    authors: Warburton KL,Urwin R,Carder M,Turner S,Agius R,Wilkinson SM

    更新日期:2015-05-01 00:00:00

  • Corticosteroid or steroid allergy?

    abstract::The aim of this study was to elucidate the role of the C11-OH substituent of the corticosteroid molecule in relation to contact allergy to corticosteroids. This group, which is essential for glucocorticoid activity, is not present in other steroid molecules, such as deoxycortisol, progestagens, testosterone, and estro...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb00286.x

    authors: Schoenmakers A,Vermorken A,Degreef H,Dooms-Goossens A

    更新日期:1992-03-01 00:00:00