Patch test reactions in atopic patients.

Abstract:

:Patch testing was carried out in 851 atopic patients; 181 atopic dermatitis (AD) patients were additionally tested with 50% dilutions of the test substances. The occurrence of allergic and irritant reactions was frequent, being 57% and 33% for AD patients aged 28-41 years and 19-27 years, respectively. Among age-matched allergic rhinitis (AR)/allergic conjunctivitis (AC) or asthma (A) patients, the number of allergic reactions varied from 25 to 30%, and for irritant reactions was 24%. In all groups, nickel, fragrance-mix, balsam of Peru and neomycin were the commonest allergens. Contact allergy to ingredients of topical medicaments was common among AD patients and patients with severe and long-lasting dermatitis were most frequently sensitized. However, sensitivity to multiple substances was not common among those patients. The number of irritant reactions was considerable, but 50% dilution of the test substances did not solve the problem.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Lammintausta K,Kalimo K,Fagerlund VL

doi

10.1111/j.1600-0536.1992.tb00235.x

keywords:

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

234-40

issue

4

eissn

0105-1873

issn

1600-0536

journal_volume

26

pub_type

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