Skin absorption from patch test systems.

abstract：:Diglycidyl ether of bisphenol A (DGEBA) is the monomer and most important contact allergen in epoxy resin(s) based on bisphenol A (DGEBA-R). Both thin-layer chromatography (TLC) and high-pressure liquid chromatography (HPLC) methods are available for the analysis of products containing DGEBA-R. With respect to detecti...

journal_title：Contact dermatitis

authors： Pontén A,Zimerson E,Sörensen O,Bruze M

更新日期：2004-05-01 00:00:00

abstract：:For more than 50 years, the Draize rabbit skin irritation test has reigned supreme as the regulatory method of choice for the identification of skin irritant chemicals. To date no in vitro alternative test has been validated as an adequate replacement. However, one potential option, to test the endpoint of concern (sk...

journal_title：Contact dermatitis

authors： Robinson MK,McFadden JP,Basketter DA

更新日期：2001-07-01 00:00:00

abstract：:Based on the information of the interdisciplinary task force on allergy diagnostics in the metal branch, in 2001, the German Contact Dermatitis Research Group (DKG) compiled two metalworking fluid (MWF) test series with currently and previously used components, respectively. After 2 years of patch testing, we present ...

journal_title：Contact dermatitis

authors： Geier J,Lessmann H,Dickel H,Frosch PJ,Koch P,Becker D,Jappe U,Aberer W,Schnuch A,Uter W

更新日期：2004-09-01 00:00:00

abstract：:The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equ...

journal_title：Contact dermatitis

authors： Sugai T,Takagi T,Yamamoto S,Takahashi Y

更新日期：1979-12-01 00:00:00

abstract：:The quantitative risk assessment (QRA) paradigm has been extended to evaluating the risk of induction of allergic contact dermatitis from consumer products. Sensitization QRA compares product-related, topical exposures to a safe benchmark, the sensitization reference dose. The latter is based on an experimentally or c...

journal_title：Contact dermatitis

authors： Farage MA,Bjerke DL,Mahony C,Blackburn KL,Gerberick GF

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis caused by (meth)acrylates is well known, both in occupational and in non-occupational settings. Contact hypersensitivity to electrocardiogram (ECG) electrodes containing (meth)acrylates is rarely reported. OBJECTIVE:To report the first case of contact dermatitis caused by acrylic...

journal_title：Contact dermatitis

authors： Stingeni L,Cerulli E,Spalletti A,Mazzoli A,Rigano L,Bianchi L,Hansel K

更新日期：2015-07-01 00:00:00

abstract：:A cohort of initially 111 office apprentices was prospectively followed for the duration of their training (2 and 3 years, respectively). The point prevalence of (slight) irritant or atopic hand eczema was 18.9% in the initial and 25.0% in the final examinations. Altogether, 37 cases of (slight) hand eczema were noted...

journal_title：Contact dermatitis

authors： Uter W,Pfahlberg A,Gefeller O,Schwanitz HJ

更新日期：1998-02-01 00:00:00

abstract：:Japanese lacquer is made from the sap of the Japanese lacquer tree (Toxicodendron vernicifluum), a member of the Anacardiacae plant family. Objects painted with this material are described collectively as lacquerware. Both fresh lacquer and lacquerware may evoke allergic contact reactions ascribable to the urushiols c...

journal_title：Contact dermatitis

authors： Kawai K,Nakagawa M,Kawai K,Miyakoshi T,Miyashita K,Asami T

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Contact allergy to epoxy (meth)acrylates, 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (bis-GMA), 2,2-bis[4-(2-hydroxy-3-acryloxypropoxy)phenyl]-propane (bis-GA), 2,2-bis[4-(methacryl-oxyethoxy)phenyl] propane (bis-EMA), 2,2-bis[4-(methacryloxy)phenyl]-propane (bis-MA), and glycidyl methacrylat...

journal_title：Contact dermatitis

authors： Aalto-Korte K,Jungewelter S,Henriks-Eckerman ML,Kuuliala O,Jolanki R

更新日期：2009-07-01 00:00:00

abstract：:Nickel-elicited systemic contact dermatitis is a well-known entity, although it is far less common than allergic contact dermatitis. In most of the cases, the main way of nickel administration is oral. Clinical manifestations are miscellaneous including pompholyx, diffuse exanthema, flexural dermatitis or baboon syndr...

journal_title：Contact dermatitis

authors： Raison-Peyron N,Guillard O,Khalil Z,Guilhou JJ,Guillot B

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Neurosensory irritation is a subjective phenomenon induced by a number of chemicals. Objectives. To investigate the sensory irritation induced by two organic solvents - n-octane and cumene - between two groups of volunteers, stingers and non-stingers, identified as such according to the results of a lactic a...

journal_title：Contact dermatitis

authors： Schliemann S,Antonov D,Manegold N,Elsner P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The prevalence of p-phenylenediamine (PPD) sensitization is 4% in the patch tested population and varies between zero and 1.5% in the general population. Hair dye is a recognised sensitization source. OBJECTIVES:To define the prevalence rates of PPD sensitization in the general and patch tested populations ...

journal_title：Contact dermatitis

authors： Vogel TA,Coenraads PJ,Bijkersma LM,Vermeulen KM,Schuttelaar ML,EDEN Fragrance Study Group.

更新日期：2015-06-01 00:00:00

abstract：:The occurrence of occupational contact dermatitis among workers in a rubber factory from 1976 to 1980 was studied. Insurance compensation was paid to 50 workers with dermatitis. 21 of the cases were allergic and 27 toxic contact dermatitis, giving a contact dermatitis frequency of 5.6/1000 workers. Paraphenylenediamin...

journal_title：Contact dermatitis

authors： Kilpikari I

更新日期：1982-11-01 00:00:00

abstract：:Machinists and machine maintenance men working in the metal industry use metal-working fluids capable of causing irritant and allergic contact dermatitis. The objectives of this study were to find out the frequency of skin symptoms in machinists and machine maintenance men (metal workers) and to compare the risk of th...

journal_title：Contact dermatitis

authors： Suuronen K,Jolanki R,Luukkonen R,Alanko K,Susitaival P

更新日期：2007-10-01 00:00:00

abstract：:3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method. All 3 resin acids were almost negative. The commercial products gave different results. While the maleic-modified product of Greek origin showed a strong s...

journal_title：Contact dermatitis

authors： Hausen BM,Hessling C

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Nickel is the most common cause of contact allergy and an important risk factor for hand eczema. Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel. OBJECTIVES:To develop and evaluate methods for visualization of ...

journal_title：Contact dermatitis

authors： Julander A,Skare L,Vahter M,Lidén C

更新日期：2011-03-01 00:00:00

abstract：:In our Department, the incidence of sensitization to cobalt has more than doubled in the last 5 years. 28% of cobalt-sensitive patients showed no other sensitivity. Of isolated cobalt sensitive patients, 68% were housewives. We determined by atomic absorption spectrophotometry with a graphite camera, the cobalt and ni...

journal_title：Contact dermatitis

authors： Vilaplana J,Grimalt F,Romaguera C,Mascaro JM

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:An inverse relationship between disease severity and health-related quality of life (HR-QoL) in patients with hand eczema is well established, but modifying effects of demographic variables have been less well studied. OBJECTIVE:To identify the influence of metropolitan versus non-metropolitan residence on ...

journal_title：Contact dermatitis

authors： Nørreslet LB,Agner T,Sørensen JA,Ebbehøj NE,Bonde JP,Fisker MH

更新日期：2018-05-01 00:00:00

abstract：:This study presents a profile of patients with chronic recalcitrant eczematous disease referred by dermatologists for contact allergy evaluation. Allergic contact dermatitis (ACD) and irritant responses were carefully defined, as was the presence or absence of atopy obtained by history. Of 410 patients studied, 44% ha...

journal_title：Contact dermatitis

authors： Klas PA,Corey G,Storrs FJ,Chan SC,Hanifin JM

更新日期：1996-02-01 00:00:00

abstract：:In this study of 152 women, comparison of patch test responses between 2 irritants over 96 h at 2 symmetrical anatomical sites is studied. 2 irritants, each at 4 different concentrations (nonanoic acid (NAA) 80%, 40%, 20%, 10%; sodium lauryl sulfate (SLS) 3%, 2%, 1% and 0.5%) and using propan-1ol and 'water for inject...

journal_title：Contact dermatitis

authors： Reiche L,Willis C,Wilkinson J,Shaw S,de Lacharrière O

更新日期：1998-11-01 00:00:00

abstract：:An outbreak of occupational dermatitis in a rubber tyre factory is reported. An unusual clinical picture was recognized. Patch tests revealed a high sensitization rate to the MBT derivative used: 2-(2'-4'dinitrophenylthio)benzothiazole. Since tests with MBT mix and dinitrophenol were negative; sensitization to a conta...

journal_title：Contact dermatitis

authors： Zina AM,Bedello PG,Cane D,Bundino S,Benedetto A

更新日期：1987-07-01 00:00:00

abstract：:Sixty-six patients who had to undergo total hip replacement by means of a metal-to-plastic Stanmore prosthesis, were patch-tested prior to and 6 to 12 months after surgery with the standard ICDRG all allergens series and with acrylic monomer 5% in acetone. In 62 patients the history of metal allergy as well as the pat...

journal_title：Contact dermatitis

authors： Nater JP,Brain RG,Deutman R,Mulder TJ

更新日期：1976-10-01 00:00:00

abstract：:The influence of "accelerants" on the percutaneous absorption of 3 organic solvents (butanol, toluene, 1,1,1-trichloroethane) was investigated in the guinea pig. DMSO in binary and ternary mixtures with various concentrations, the result of adding 0.1 M C18 fatty acids, and of pretreatment with DMSO and olive oil, wer...

journal_title：Contact dermatitis

authors： Boman A

更新日期：1989-11-01 00:00:00

abstract：:Repeated open application tests (ROATs) were performed with common ingredients of vehicles in 86 patients with contact dermatitis. The substances were applied twice daily for 7 days to the flexor aspect of the forearm near the cubital fossa, unless dermatitis appeared earlier. Of the patients with a questionable (?+) ...

journal_title：Contact dermatitis

authors： Hannuksela M,Salo H

更新日期：1986-04-01 00:00:00

abstract：:An outbreak of dermatitis occurred in an aircraft factory using epoxy resin composite material. Of 25 operatives, 14 gave positive patch test reactions to the composite material and/or diglycidylether of bisphenol A (DGEBA), tetraglycidyl-4,4'-methylene dianiline (TGMDA), and o-diglycidyl phthalate. This report seems ...

journal_title：Contact dermatitis

authors： Burrows D,Fregert S,Campbell H,Trulsson L

更新日期：1984-08-01 00:00:00

abstract：:The aim of the study is to describe the ability of patients with allergic contact dermatitis to avoid exposure to allergens in cosmetics. The study is a questionnaire survey among 382 patients with contact allergy to preservatives and fragrances, included from 3 dermatological clinics. The questionnaire included quest...

journal_title：Contact dermatitis

authors： Noiesen E,Munk MD,Larsen K,Johansen JD,Agner T

更新日期：2007-08-01 00:00:00

abstract：:Piroxicam (PXM) is a nonsteroidal anti-inflammatory drug which may induce a photosensitive eruption shortly after administration. We examined whether animals sensitized to thimerosal developed a photosensitivity to PXM. Male Hartley strain guinea pigs were sensitized to thimerosal, thiosalicylate and PXM separately. T...

journal_title：Contact dermatitis

authors： Kitamura K,Osawa J,Ikezawa Z,Nakajima H

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Occlusion of the skin is a risk factor for development of irritant contact dermatitis. Occlusion may, however, have a positive effect on skin healing. No consensus on the effect of occlusion has been reached. OBJECTIVES:To investigate skin barrier response to occlusion on intact and damaged skin. METHODS:I...

journal_title：Contact dermatitis

authors： Jungersted JM,Høgh JK,Hellgren LI,Jemec GB,Agner T

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Exposure to humid environments/water and prolonged glove occlusion are both believed to cause irritant contact dermatitis. OBJECTIVES:To study the effects of different forms of wet work, especially the differences between water exposure and occlusion, by using an experimental model simulating occupational w...

journal_title：Contact dermatitis

authors： Fartasch M,Taeger D,Broding HC,Schöneweis S,Gellert B,Pohrt U,Brüning T

更新日期：2012-10-01 00:00:00

abstract：:3 patients with contact dermatitis to an ethyl cyanoacrylate glue are presented. Although reactions to cyanoacrylate glues are considered rare, more widespread use of these products by nail salons is likely to be associated with an increased incidence of positive reactions. All 3 of our patients came into contact with...

journal_title：Contact dermatitis

authors： Belsito DV

更新日期：1987-10-01 00:00:00