Nickel allergy--prevalence in a population of Swedish youths from patch test and questionnaire data.


BACKGROUND:The prevalence of body piercing and orthodontic treatment has increased during recent decades. Such changes in lifestyle may influence the occurrence of nickel allergy. OBJECTIVES:The aim of this study was to describe the prevalence of nickel allergy in a Swedish youth population. METHODS:In a cross-sectional survey, 6095 adolescents answered a questionnaire on their lifestyle and medical history, and 4439 consented to patch testing for contact allergy. Patch test results were adjusted for dropouts by a missing value analysis. RESULTS:The prevalence of self-reported dermatitis from contact with metal items was 14.8%. Patch testing showed nickel sensitization in 9.9% of the subjects, and in significantly more girls than boys, 13.3% versus 2.5%, respectively. Taking the dropout into account, the estimated true prevalence of nickel sensitivity evaluated by test reading at D4 is 11.8% in girls and 1.6% in boys. CONCLUSIONS:The prevalence of nickel sensitization was higher for girls and slightly lower for boys compared with previous Swedish data. Self-reported information on metal dermatitis as an estimate of nickel allergy has low validity. When possible, missing value analysis should be performed to account for dropouts.


Contact Dermatitis


Contact dermatitis


Fors R,Persson M,Bergström E,Stenlund H,Stymne B,Stenberg B




Has Abstract


2008-02-01 00:00:00














  • Hyperkeratotic hand eczema: Eczema or not?

    abstract:BACKGROUND:Hyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology. OBJECTIVE:To investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE. METHODS:Palmar skin biopsies (lesional and perilesional) were ob...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Politiek K,Loman L,Pas HH,Diercks GFH,Lemmink HH,Jan SZ,van den Akker PC,Bolling MC,Schuttelaar MLA

    更新日期:2020-09-01 00:00:00

  • The hands in health and disease of individuals with filaggrin loss-of-function mutations: clinical reflections on the hand eczema phenotype.

    abstract::During the last 2 years, we have performed filaggrin genotyping in patients with eczema seen in our hand eczema clinic. We present pictures of healthy and diseased hands from individuals with filaggrin gene (FLG) mutations to describe a clinical entity of hand eczema. We show that xerosis and hyperkeratosis on the dor...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Kaae J,Menné T,Carlsen BC,Zachariae C,Thyssen JP

    更新日期:2012-09-01 00:00:00

  • The validity of rating patch test reactions based on digital images.

    abstract:BACKGROUND:The proper reading of patch test (PT) reactions, based on morphological criteria, is of utmost importance. Digital images are increasingly used for medical training. OBJECTIVES:To assess the diagnostic validity of readings of 20 digital images of various PT reaction grades by congress attendants. METHODS:1...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Uter W,Becker D,Schnuch A,Gefeller O,Frosch PJ

    更新日期:2007-11-01 00:00:00

  • Occupational dermatoses from cutting oils.

    abstract::230 patients with occupational dermatitis in the metallurgic industry were studied with standard patch test (GEIDC) and an oil series. An occupational and clinical questionnaire survey was carried out. Responses to paraphenylenediamine, chrome, cobalt in the standard series, and benzisothiazolone, triethanolamine, and...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Alomar A,Conde-Salazar L,Romaguera C

    更新日期:1985-03-01 00:00:00

  • Anaphylaxis due to formaldehyde released from root-canal disinfectant.

    abstract::A 50-year-old woman developed anaphylaxis 8 h after application of a paraformaldehyde-containing root canal disinfectant. Radioallergosorbent test showed that she had a high level of formaldehyde-specific IgE in her serum. Prick tests to formaldehyde and paraformaldehyde showed immediate-type responses to both. We rev...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审


    authors: Kunisada M,Adachi A,Asano H,Horikawa T

    更新日期:2002-10-01 00:00:00

  • Higher allergenicity of high molecular weight hydrolysed wheat protein in cosmetics for percutaneous sensitization.

    abstract:BACKGROUND:Wheat protein derivatives are used in a variety of products worldwide. Gluten is commercially used 'as is' or with modifications such as hydrolysis, which is carried out to overcome its insolubility. Several cases of contact urticaria following exposure to hydrolysed wheat protein (HWP) in cosmetics or of an...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Chinuki Y,Takahashi H,Dekio I,Kaneko S,Tokuda R,Nagao M,Fujisawa T,Morita E

    更新日期:2013-02-01 00:00:00

  • Comparative sensitizing potencies of fragrances, preservatives, and hair dyes.

    abstract::The local lymph node assay (LLNA) is used for assessing sensitizing potential in hazard identification and risk assessment for regulatory purposes. Sensitizing potency on the basis of the LLNA is categorized into extreme (EC3 value of ≤0.2%), strong (>0.2% to ≤2%), and moderate (>2%). To compare the sensitizing potenc...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审


    authors: Lidén C,Yazar K,Johansen JD,Karlberg AT,Uter W,White IR

    更新日期:2016-11-01 00:00:00

  • Nickel contact allergy and menstrual cycle.

    abstract::According to some reports in the literature, the hormonal fluctuations which occur during the menstrual cycle may affect the clinical expression of contact allergy to a greater or lesser degree. In clinical practice, too, patient history often shows exacerbation of the contact dermatitis during the days immediately pr...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Bonamonte D,Foti C,Antelmi AR,Biscozzi AM,Naro ED,Fanelli M,Loverro G,Angelini G

    更新日期:2005-06-01 00:00:00

  • Occupational airborne contact dermatitis caused by thyme dust.

    abstract::The aim of the study was to assess occupational hazards to the farmer's skin associated with processing thyme (Thymus vulgaris L.). 46 farmers were studied during the threshing of dried thyme. They were questioned about work-related skin problems and examined before and after work. In all persons, serum thyme-specific...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Spiewak R,Skorska C,Dutkiewicz J

    更新日期:2001-04-01 00:00:00

  • Patterns of simultaneous patch test reactions to thiurams and dithiocarbamates in 164 patients.

    abstract:BACKGROUND:Thiurams and dithiocarbamates are structurally related sensitizing rubber accelerators. OBJECTIVES:To study patterns of simultaneous patch test reactions to thiurams and dithiocarbamates at the Finnish Institute of Occupational Health in 1991-2015. METHODS:We searched the patch test files for patients with...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Aalto-Korte K,Pesonen M

    更新日期:2016-12-01 00:00:00

  • The epidemiology of hand eczema in the general population--prevalence and main findings.

    abstract::Numerous studies have investigated the prevalence and risk factors of hand eczema in the general population. These studies are of high value as they tend to be less biased than studies using clinical populations and as they are important for healthcare decision makers when they allocate resources. This study aimed to ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审


    authors: Thyssen JP,Johansen JD,Linneberg A,Menné T

    更新日期:2010-02-01 00:00:00

  • Application of a 4-h human patch test method for comparative and investigative assessment of skin irritation.

    abstract::A human 4-h patch test has recently been developed for testing the irritation hazard potential of chemicals. The original method was developed for comparative irritation assessments relative to benchmark irritants using simple statistical tests. In this context, the method has been shown to be robust in intralaborator...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Robinson MK,Perkins MA,Basketter DA

    更新日期:1998-04-01 00:00:00

  • Allergic contact dermatitis caused by alkyl glucosides.

    abstract:BACKGROUND:Alkyl glucosides were not expected to have a sensitizing potential at the concentrations to be used in finished consumer products; however, several contact allergy cases have been published. OBJECTIVES:To report on the patients suffering from allergic contact dermatitis caused by alkyl glucosides observed i...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Gijbels D,Timmermans A,Serrano P,Verreycken E,Goossens A

    更新日期:2014-03-01 00:00:00

  • Allergic contact dermatitis from 2-n-octyl-4-isothiazolin-3-one, a paint mildewcide.

    abstract::Severe allergic contact dermatitis from a paint mildewcide, 2-n-octyl-4-isothiazolin-3-one, developed in a worker formulating latex paints within a paint manufacturing company, Guinea pig maximization testing demonstrated this to be a moderate sensitizer. Further cases of allergic contact dermatitis may be encountered...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Mathias CG,Andersen KE,Hamann K

    更新日期:1983-11-01 00:00:00

  • Lichenoid photocontact dermatitis to musk ambrette.

    abstract::A patient is described with a pigmentary dermatitis of the face with histological features of a lichenoid reaction, which proved to be a photocontact dermatitis to musk ambrette. Photopatch tests produced a pigmented dermatitis that reflected the clinical and histological features of a lichenoid reaction, which occurr...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Parodi G,Guarrera M,Rebora A

    更新日期:1987-03-01 00:00:00

  • Patch testing to detect corticosteroid allergy: is it adequate?

    abstract::Whilst patch testing with corticosteroids in ethanol is more sensitive than either petrolatum or the cream formulation, the frequency of false-negative reactions is not known. We have compared patch testing with corticosteroid at 1% in ethanol with intradermal (i.d.) tests using 1 mg corticosteroid suspended in normal...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Seukeran DC,Wilkinson SM,Beck MH

    更新日期:1997-03-01 00:00:00

  • Epidemiological, clinical and allergological observations on pompholyx.

    abstract::We have studied a group of 104 patients with pompholyx, to investigate the relationship between allergological factors and its etiopathogenesis. The following examinations were performed: blood sampling (routine tests and IgE levels), allergological tests (patch, prick, intradermal, and oral provovation tests with nic...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Lodi A,Betti R,Chiarelli G,Urbani CE,Crosti C

    更新日期:1992-01-01 00:00:00

  • Outcome of a second patch test reading of TRUE Tests® on D6/7.

    abstract::Background. Two readings of patch test reactions are recommended. Objectives. To evaluate the outcome of a second patch test reading of TRUE Test® allergens on D6/7 in relation to negative or doubtful reactions on D3/4. Methods. This was a retrospective investigation of patch test data from January 1992 to October 201...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Madsen JT,Andersen KE

    更新日期:2013-02-01 00:00:00

  • A patch test closet.

    abstract::A way of adapting a treatment room for patch test purposes is described. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Epstein E

    更新日期:1975-06-01 00:00:00

  • Occurrence and prognosis of hand eczema in the car industry: results from the PACO follow-up study (PACO II).

    abstract:BACKGROUND:Only a few epidemiological studies on hand eczema (HE) in the metalworking industry have been conducted, and no study has attempted a long-term follow-up. OBJECTIVES:In the Prospective Audi Cohort (PACO) II follow-up study, we aimed to estimate burden and prognosis of HE in a car industry setting (follow-up...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Apfelbacher CJ,Radulescu M,Diepgen TL,Funke U

    更新日期:2008-06-01 00:00:00

  • Effect of an antioxidant (quercetin) on sodium-lauryl-sulfate-induced skin irritation.

    abstract::Quercetin is a bioflavonoid with antioxidant and anti-inflammatory activity. The purpose of this study was to examine the effect of quercetin on acute skin irritation, with special interest in the skin barrier function recovery. Acute irritant contact dermatitis was induced in 15 patients by 24-h occlusion of 2% sodiu...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Katsarou A,Davoy E,Xenos K,Armenaka M,Theoharides TC

    更新日期:2000-02-01 00:00:00

  • The effect of the guinea pig maximization protocol on the irritant response to deodorized kerosene - the excited skin syndrome.

    abstract::Deodorized kerosene in a concentration of 50 g/100 g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The respon...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Nethercott JR,Lawrence M

    更新日期:1983-11-01 00:00:00

  • Occupational peri-ocular contact dermatitis due to sensitization against black rubber components of a microscope.

    abstract::A 24-year-old female working in the Department of Pathology of a University Hospital developed an acute peri-ocular eczema clearly being related to her daily work at the microscope. Patch testing revealed delayed type hypersensitivity against the black rubber mix, N-isopropyl-N'-phenyl paraphenylenediamine, N-cyclohex...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Kuijpers DI,Hillen F,Frank JA

    更新日期:2006-08-01 00:00:00

  • Comparison of diagnostic methods in latex surgical glove contact urticaria.

    abstract::Surgical rubber gloves contain allergens derived from natural rubber latex which may sensitize, causing contact urticaria and even systemic reactions. We examined 15 hospital employees allergic to latex surgical gloves, using various skin tests and RAST, to determine the most reliable diagnostic method and to investig...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Turjanmaa K,Reunala T,Räsänen L

    更新日期:1988-10-01 00:00:00

  • PAFS: population-adjusted frequency of sensitization. (I) Influence of sex and age.

    abstract::Sensitization rates are influenced by sex and age. Crude rates from different departments cannot be compared without taking into account these variables. However, the influence of sex and age has never been considered quantitatively. In 2 hypothetical populations with identical age-specific sensitizations rates, but d...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Schnuch A

    更新日期:1996-06-01 00:00:00

  • Methacrylates in dental restorative materials.

    abstract::Commercial dental restorative materials were analysed in order to obtain information about the occurrence of sensitizing acrylates. Acetone-soluble methacrylates of 7 bonding materials, 8 composite resins and 2 glass ionomers were identified by gas chromatography with mass-selective detection and quantified by liquid ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Henriks-Eckerman ML,Suuronen K,Jolanki R,Alanko K

    更新日期:2004-04-01 00:00:00

  • Prognosis of contact dermatitis in epoxy resin workers.

    abstract::Between January 1993 and February 2002, 40 of 1354 (3%) workers who attended a tertiary referral occupational dermatology clinic were diagnosed with allergic contact dermatitis (ACD) from epoxy resin systems (ER). 20 of these patients were followed up at least 2 years post-diagnosis to establish prognosis. Characteris...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Cahill J,Keegel T,Dharmage S,Nugriaty D,Nixon R

    更新日期:2005-03-01 00:00:00

  • Sunflower allergy. On the constituents of the trichomes of Helianthus annuus L. (Compositae).

    abstract::Sesquiterpene lactones (STL) of the sunflower, occurring in fragile multicellular capitate glandular hairs, have been shown to display a remarkable sensitizing capacity when investigated by experimental sensitization in guinea pigs. The strongest response was induced by the hemiketal form of 1-O-methyl-4,5-dihydronive...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Hausen BM,Spring O

    更新日期:1989-05-01 00:00:00

  • Patch test reactions to metal salts in patients with oral mucosal lesions associated with amalgam restorations.

    abstract::Patch testing with various metal salts was performed in patients with oral mucosal lesions associated with amalgam restorations, by using polypropylene-coated aluminium discs. Positive reactions to mercuric chloride were obtained in 5/12 (42%) of these patients, but only in 1/11 patients (9%) with oral mucosal lesions...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Nordlind K,Lidén S

    更新日期:1992-09-01 00:00:00

  • Hand eczema among Hong Kong nurses: a self-report questionnaire survey conducted in a regional hospital.

    abstract:BACKGROUND:Hand eczema is common in the nursing profession, and has been reported widely in various parts of the world. OBJECTIVES:The aim of this study was to determine the prevalence and severity of hand eczema among nurses working in a regional hospital in Hong Kong, as well as its psychosocial impact and any possi...

    journal_title:Contact dermatitis

    pub_type: 杂志文章


    authors: Luk NM,Lee HC,Luk CK,Cheung YY,Chang MC,Chao VK,Ng SC,Tang LS

    更新日期:2011-12-01 00:00:00