Structure-activity relationships in allergic contact dermatitis induced by methacrylates. Studies of the influence of side-chain length of methacrylates.

abstract：:The quantitative risk assessment (QRA) paradigm has been extended to evaluating the risk of induction of allergic contact dermatitis from consumer products. Sensitization QRA compares product-related, topical exposures to a safe benchmark, the sensitization reference dose. The latter is based on an experimentally or c...

journal_title：Contact dermatitis

authors： Farage MA,Bjerke DL,Mahony C,Blackburn KL,Gerberick GF

更新日期：2003-09-01 00:00:00

abstract：:To investigate the mechanisms of non-immunologic contact urticaria (NICU), the effect of 120 mg of terfenadine (H1-antagonist) on contact reactions to methyl nicotinate, diethyl fumarate, benzoic acid, cinnamic acid, cinnamic aldehyde and dimethyl sulfoxide was studied in 20 subjects. Erythema and edema were observed ...

journal_title：Contact dermatitis

authors： Lahti A

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Contact allergy to epoxy (meth)acrylates, 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (bis-GMA), 2,2-bis[4-(2-hydroxy-3-acryloxypropoxy)phenyl]-propane (bis-GA), 2,2-bis[4-(methacryl-oxyethoxy)phenyl] propane (bis-EMA), 2,2-bis[4-(methacryloxy)phenyl]-propane (bis-MA), and glycidyl methacrylat...

journal_title：Contact dermatitis

authors： Aalto-Korte K,Jungewelter S,Henriks-Eckerman ML,Kuuliala O,Jolanki R

更新日期：2009-07-01 00:00:00

abstract：:A case is reported of a foam rubber carrier with pustular lesions on the arms, wrists, thighs and trunk. Scratch and patch testing with the foam rubber components was negative. Animal testing revealed sodium hexafluorosilicate (Na2SiF6), one of the ingredients of the foam rubber, to be a pustulogen on previously damag...

journal_title：Contact dermatitis

authors： Dooms-Goossens A,Loncke J,Michiels JL,Degreef H,Wahlberg J

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Alkyl glucosides were not expected to have a sensitizing potential at the concentrations to be used in finished consumer products; however, several contact allergy cases have been published. OBJECTIVES:To report on the patients suffering from allergic contact dermatitis caused by alkyl glucosides observed i...

journal_title：Contact dermatitis

authors： Gijbels D,Timmermans A,Serrano P,Verreycken E,Goossens A

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series. OBJECTIVES:To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a ...

journal_title：Contact dermatitis

authors： Isaksson M,Inerot A,Lidén C,Matura M,Stenberg B,Möller H,Bruze M

更新日期：2011-07-01 00:00:00

abstract：:Exposure to formaldehyde is common from both consumer products and industry. The reliability of the patch test is essential for the diagnosis of formaldehyde allergy as it is difficult to suspect from the patient's history. The recommended formaldehyde patch test concentration has been reduced over the last decades fr...

journal_title：Contact dermatitis

authors： Trattner A,Johansen JD,Menné T

更新日期：1998-01-01 00:00:00

abstract：:Data suggests that protection from gloves is paradoxically reduced because of effects of occlusion on the skin. The aim of this study was to characterize these effects on physical and functional properties of stratum corneum. Volunteer trials were conducted using patches of polyvinyl chloride (PVC) glove material on t...

journal_title：Contact dermatitis

authors： Graves CJ,Edwards C,Marks R

更新日期：1995-09-01 00:00:00

abstract：:Sixty-six patients who had to undergo total hip replacement by means of a metal-to-plastic Stanmore prosthesis, were patch-tested prior to and 6 to 12 months after surgery with the standard ICDRG all allergens series and with acrylic monomer 5% in acetone. In 62 patients the history of metal allergy as well as the pat...

journal_title：Contact dermatitis

authors： Nater JP,Brain RG,Deutman R,Mulder TJ

更新日期：1976-10-01 00:00:00

abstract：:In our Department, the incidence of sensitization to cobalt has more than doubled in the last 5 years. 28% of cobalt-sensitive patients showed no other sensitivity. Of isolated cobalt sensitive patients, 68% were housewives. We determined by atomic absorption spectrophotometry with a graphite camera, the cobalt and ni...

journal_title：Contact dermatitis

authors： Vilaplana J,Grimalt F,Romaguera C,Mascaro JM

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis is known to occur in children with and without atopic dermatitis, but more data are needed on contact sensitization profiles in these two groups. OBJECTIVES:To identify frequent allergens in children with and without atopic dermatitis suspected of having allergic contact dermatit...

journal_title：Contact dermatitis

authors： Lubbes S,Rustemeyer T,Sillevis Smitt JH,Schuttelaar ML,Middelkamp-Hup MA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases. OBJECTIVES:To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols and/or Amerchol™ L-101)...

journal_title：Contact dermatitis

authors： Fransen M,Overgaard LEK,Johansen JD,Thyssen JP

更新日期：2018-01-01 00:00:00

abstract：:Henna (Lawsonia inermis, family Lythraceae) is a shrub cultivated in India, Sri Lanka and North Africa and contains the active dye lawsone (2-hydroxy-1,4-naphthoquinone). Henna dye is obtained from the dried leaves, which are powdered and mixed with oil or water and are used to prepare hair and body dyes. Temporary he...

journal_title：Contact dermatitis

authors： Kang IJ,Lee MH

更新日期：2006-07-01 00:00:00

abstract：:Between January 1993 and February 2002, 40 of 1354 (3%) workers who attended a tertiary referral occupational dermatology clinic were diagnosed with allergic contact dermatitis (ACD) from epoxy resin systems (ER). 20 of these patients were followed up at least 2 years post-diagnosis to establish prognosis. Characteris...

journal_title：Contact dermatitis

authors： Cahill J,Keegel T,Dharmage S,Nugriaty D,Nixon R

更新日期：2005-03-01 00:00:00

abstract：:Pimecrolimus suppresses the proinflammatory cytokine production of cutaneous T and mast cells (1). It is used to treat atopic dermatitis and is the active ingredient in the topical formulation pimecrolimus 1.0% cream (Elidel, Novartis Pharma AG, Basel, Switzerland). ...

journal_title：Contact dermatitis

authors： Saitta P,Brancaccio R

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:There is a lack of prospective studies investigating contact sensitization in patients with chronic leg ulcers. OBJECTIVES:To determine the frequency of contact sensitization in patients with chronic leg ulcers using a special series of patch tests and to determine whether the number of sensitizations was c...

journal_title：Contact dermatitis

authors： Barbaud A,Collet E,Le Coz CJ,Meaume S,Gillois P

更新日期：2009-05-01 00:00:00

abstract：:16 children with atopic dermatitis and 4 nonatopics were skin tested with flavourings and perfumes. Immediate reactions to balsam of Peru and fragrance-mix were found in 9 atopics, and none among nonatopics. An irritant is more probable than an immunologic mechanism. Allergen solutions should probably be assayed at a ...

journal_title：Contact dermatitis

authors： Abifadel R,Mortureux P,Perromat M,Ducombs G,Taieb A

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Hand eczema is a disease with large variation in clinical presentation and severity. Scoring systems for quantitative severity assessment exist. However, they are observer-dependent. An objective quantitative tool for scoring of hand eczema would improve categorization of hand eczema. OBJECTIVE:To investiga...

journal_title：Contact dermatitis

authors： Hald M,Thyssen JP,Zachariae C,Røpke MA,Carstensen JM,Schultz N,Johansen JD

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The former 'EU Nickel Directive' and, since 2009, the REACH Regulation (item 27 of Annex XVII) do not include all metallic objects. The nickel content of tools is not regulated by the REACH Regulation, even if they may come into in prolonged contact with the skin. Tools might be possible sources of nickel an...

journal_title：Contact dermatitis

authors： Kickinger-Lörsch A,Bruckner T,Mahler V

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Wheat protein and its derivatives can cause protein contact dermatitis (PCD), which mainly occurs in bakers. Few studies have attempted to identify the allergens responsible for wheat PCD. OBJECTIVES:The aim of this study was to identify allergenic wheat proteins in patients with wheat PCD. METHODS:Water-s...

journal_title：Contact dermatitis

authors： Matsuo H,Uemura M,Yorozuya M,Adachi A,Morita E

更新日期：2010-07-01 00:00:00

abstract：:The consequences of a diagnosis of occupational contact dermatitis (OCD) were investigated using cases available from the voluntary surveillance scheme, EPIDERM. Cases of OCD reported from November 1994 to September 1995 were identified and sampled to give at least 100 cases of allergic, irritant and mixed OCD reporte...

journal_title：Contact dermatitis

authors： Adisesh A,Meyer JD,Cherry NM

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Cosensitization to nickel, cobalt and chromium occurs in the general population and in some occupational groups. OBJECTIVES:To estimate the isolated and concurrent occurrence of nickel, cobalt and chromium contact sensitization and their association with individual and occupational risk factors. PATIENTS/M...

journal_title：Contact dermatitis

authors： Rui F,Bovenzi M,Prodi A,Fortina AB,Romano I,Corradin MT,Filon FL

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:An acute viral cold is a very common illness and is characterized by sneezing and a runny nose. Because of rhinorrhea and frequent use of handkerchiefs, the skin around the nose feels uncomfortably dry and flaky. OBJECTIVES/METHODS:To evaluate the nasolabial skin barrier impairment, 14 female volunteers wit...

journal_title：Contact dermatitis

authors： Houben E,Adam R,Hachem JP,Roseeuw D,Rogiers V,De Paepe K

更新日期：2008-11-01 00:00:00

abstract：:The allergenicity and the cross-reactivity of naphthenic acid (NA) and its metallic salts were evaluated in experimental animals. In the guinea pig maximization test, sensitizing skin reactions were observed with cobalt naphthenate (CoN), zinc naphthenate (ZnN) and NA, but not with copper naphthenate, with CoN being t...

journal_title：Contact dermatitis

authors： Yamano T,Shimizu M,Noda T

更新日期：2006-01-01 00:00:00

abstract：:Surgical rubber gloves contain allergens derived from natural rubber latex which may sensitize, causing contact urticaria and even systemic reactions. We examined 15 hospital employees allergic to latex surgical gloves, using various skin tests and RAST, to determine the most reliable diagnostic method and to investig...

journal_title：Contact dermatitis

authors： Turjanmaa K,Reunala T,Räsänen L

更新日期：1988-10-01 00:00:00

abstract：:Although hand hygiene is an important and inexpensive measure to prevent nosocomial infections in clinical settings, the compliance of healthcare workers remains low. In Europe, alcoholic hand disinfection is first choice, but there exists a limited user acceptability due to estimated adverse effects on skin condition...

journal_title：Contact dermatitis

authors： Houben E,De Paepe K,Rogiers V

更新日期：2006-05-01 00:00:00

abstract：:The new Dangerous Preparations Directive (DPD, 1999/45/EC) introduces a special labelling requirement for skin sensitizers in products that are regulated under this Directive. The packaging of products containing 0.1% of a sensitizer must bear the inscription "Contains 'name of sensitizer'. May produce an allergic rea...

journal_title：Contact dermatitis

authors： Roggeband R,Basketter DA,De Groot AC,Robinson MK,Gerberick GF

更新日期：2001-06-01 00:00:00

abstract：:For more than 50 years, the Draize rabbit skin irritation test has reigned supreme as the regulatory method of choice for the identification of skin irritant chemicals. To date no in vitro alternative test has been validated as an adequate replacement. However, one potential option, to test the endpoint of concern (sk...

journal_title：Contact dermatitis

authors： Robinson MK,McFadden JP,Basketter DA

更新日期：2001-07-01 00:00:00

abstract：:A patient is described with a pigmentary dermatitis of the face with histological features of a lichenoid reaction, which proved to be a photocontact dermatitis to musk ambrette. Photopatch tests produced a pigmented dermatitis that reflected the clinical and histological features of a lichenoid reaction, which occurr...

journal_title：Contact dermatitis

authors： Parodi G,Guarrera M,Rebora A

更新日期：1987-03-01 00:00:00

abstract：:In some patients with atopic dermatitis (AD), delayed-type allergy to aeroallergens, such as house dust mite, can be demonstrated by patch testing. Positive patch tests can be expected only in patients with AD and, in them, only to aeroallergens to which type 1 reactions have also been demonstrated. In an as yet unkno...

journal_title：Contact dermatitis

authors： de Groot AC,Young E

更新日期：1989-10-01 00:00:00