Abstract：
:The purpose of this study was to investigate the role of contact hypersensitivity (CHS) in adult widespread eczema (WE) and to analyse the aetiology of WE. 108 consecutive adult WE patients were patch tested. 352 patients with suspected localized allergic contact dermatitis (ACD) tested in the same period served as a control. The average age of the patients with WE was significantly greater than the control group (47.6 +/- 15.0 v 39.2 +/- 14.9, p < 0.01, Student's t-test). More male patients were found in the WE group (42.6% vs 25.0%, p < 0.01, chi2-test). 71 (65.7%) of the WE patients were patch test positive. ACD was diagnosed in 29 out of 108 (26.9% of the WE patients and 40.8% of the PT positive patients) WE patients. ACD was also suspected in another 42 patients (39.8%), who had at least 1 positive PT result but the relevance of PT was hard to determine. In the remaining 37 patch test negative patients, 2 cases of food allergy were diagnosed by clinical findings and open food challenge test. 1 case of atopic dermatitis was diagnosed. 34 patients (31.5%) were diagnosed as unclassified endogenous eczema. Most of the WE patients with ACD (15/29, 51.7%) were ACD from widespread contact with hair dye during bathing. Most of the WE patients with hair dye ACD were male (male : female = 2.75). The total positive rates of PT in the WE group were no different to the control (65.7% vs 61.5%, p > 0.05, chi2-test). No significant difference was found for the positive rates of common contact allergens. The rate of atopy was no different between the 2 groups either (6.5% v 5.1%, p > 0.01, chi2-test). These results indicated that contact sensitization was very common in adult WE. Neglected widespread contact with contact allergens, especially hair dye, plays a very important role in our adult WE. The roles of age and sex in WE need to be studied further.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Li LF,Wang Jdoi
10.1034/j.1600-0536.2002.470605.xkeywords:
subject
Has Abstractpub_date
2002-12-01 00:00:00pages
341-4issue
6eissn
0105-1873issn
1600-0536pii
cod470605journal_volume
47pub_type
杂志文章abstract：:3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method. All 3 resin acids were almost negative. The commercial products gave different results. While the maleic-modified product of Greek origin showed a strong s...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1990.tb03229.x
更新日期：1990-08-01 00:00:00
abstract：:The results of patch tests with colophony in the standard series between 1983 and 1987 were analyzed. 5521 patients were tested in the Department of Dermatology, Hamburg, while 354 were tested in other clinics and private practices. Colophony was positive in 2.4% and 11.9%, respectively. Out of 62 patients in the 1st ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1989.tb03149.x
更新日期：1989-04-01 00:00:00
abstract：:The present report describes experimental studies on the proteolytic activity of the secretion on the surface of okra pods and the allergenicity of okra components, to clarify the etiology of skin lesions due to okra. Proteolytic activity was detected on the surface of immature okra pods and seemed to be sufficient to...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1992.tb00891.x
更新日期：1992-02-01 00:00:00
abstract：UNLABELLED:BACKGROUND. Allergens included in the European baseline series should result in positive patch test reactions in at least 1% of a patch test population. Inclusion of local anaesthetics other than benzocaine in the baseline series has previously been debated. OBJECTIVES:To investigate temporal trends of benz...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2010.01858.x
更新日期：2011-08-01 00:00:00
abstract：:As part of the investigation of sources of exposure to rosin allergens, disposable diapers (napkins) common on the Swedish market were analyzed, using gas chromatography, to detect the main rosin compounds. Rosin components were detected in all diapers, the highest amounts in those from the 2 major producers. In these...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1996.tb02169.x
更新日期：1996-03-01 00:00:00
abstract：:Tween 80 is an ethoxylated hydrophilic non-ionic surfactant, which is used for the preparation of oil-in-water emulsions in pharmaceutical products, cosmetics, and industrial detergents. Ethoxylated surfactants are polyethers and are thus easily oxidized by atmospheric oxygen to a variety of hydroperoxides, peroxides ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1997.tb00368.x
更新日期：1997-07-01 00:00:00
abstract：:Thiomersal is the preservative in all toxoid vaccines routinely administered to children in the UK, but exposure from other sources is uncommon. Delayed hypersensitivity to thiomersal was demonstrated in 1% of individuals attending the Contact Dermatitis Investigation Unit, and 50 of these patients with positive patch...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1988.tb02809.x
更新日期：1988-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The aim of this cross-sectional study was to collect data on the prevalence of hand eczema and relevant risk factors in geriatric nurses in Germany. METHODS:1375 geriatric nurses from 86 nursing homes were investigated by 41 occupational physicians. RESULTS:Hand eczema was diagnosed in 243 n...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2008.01496.x
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:Cosensitization to nickel, cobalt and chromium occurs in the general population and in some occupational groups. OBJECTIVES:To estimate the isolated and concurrent occurrence of nickel, cobalt and chromium contact sensitization and their association with individual and occupational risk factors. PATIENTS/M...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2012.02100.x
更新日期：2012-12-01 00:00:00
abstract：:3 patients with contact dermatitis to an ethyl cyanoacrylate glue are presented. Although reactions to cyanoacrylate glues are considered rare, more widespread use of these products by nail salons is likely to be associated with an increased incidence of positive reactions. All 3 of our patients came into contact with...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1987.tb02719.x
更新日期：1987-10-01 00:00:00
abstract：:During a 5-year period, 3664 consecutive patients were patch tested in a private dermatology practice with the Standard Series of the International Contact Dermatitis Research Group (ICDRG). 454 of these were tested with one or more additional substances which were suspected of having caused their dermatitis. 194 of t...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1983.tb04396.x
更新日期：1983-07-01 00:00:00
abstract：:A 45-year-old woman developed dermatitis of the face after she applied a cosmetic package comprising day and night creams. Patch tests were performed with the British Contact Dermatitis Society (BCDS) standard, bases + preservatives, and cosmetic series in addition to samples of both creams and the individual constitu...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2007.00972.x
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:An acute viral cold is a very common illness and is characterized by sneezing and a runny nose. Because of rhinorrhea and frequent use of handkerchiefs, the skin around the nose feels uncomfortably dry and flaky. OBJECTIVES/METHODS:To evaluate the nasolabial skin barrier impairment, 14 female volunteers wit...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2008.01425.x
更新日期：2008-11-01 00:00:00
abstract：:Sixty-six patients who had to undergo total hip replacement by means of a metal-to-plastic Stanmore prosthesis, were patch-tested prior to and 6 to 12 months after surgery with the standard ICDRG all allergens series and with acrylic monomer 5% in acetone. In 62 patients the history of metal allergy as well as the pat...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1976.tb03044.x
更新日期：1976-10-01 00:00:00
abstract：:Contact allergy to dental allergens is a well-studied subject, more so among dental professionals than dental patients. 1632 subjects had been patch tested to either the dental patient series or dental personnel series at the department of Occupational and Environmental Dermatology, Malmö, Sweden. Positive patch tests...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2006.00922.x
更新日期：2006-10-01 00:00:00
abstract：:Reactivity of white and hispanic skin after exposure to sodium lauryl sulphate (SLS) has been investigated. The tests were performed on the back as follows: untreated skin, skin pre-treated with short-term occlusion and delipidized skin. Irritant reactions were induced by applying 0.5% and 2.0% SLS via Finn chamber pa...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1988.tb05512.x
更新日期：1988-08-01 00:00:00
abstract：:3-Iodo-2-propynyl-butylcarbamate (IPBC) is a fungicide used in both industrial products and cosmetics. We report the first case of allergic contact dermatitis from airborne exposure to this preservative. A 34-year-old female production worker at a paint factory developed dermatitis on air-exposed skin areas. Patch tes...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2003.00079.x
更新日期：2003-03-01 00:00:00
abstract：:In the present study, we have investigated 42 cosmetic products based on natural ingredients for content of 11 fragrance substances: geraniol, hydroxycitronellal, eugenol, isoeugenol, cinnamic aldehyde, cinnamic alcohol, alpha-amylcinnamic aldehyde, citral, coumarin, dihydrocoumarin and alpha-hexylcinnamic aldehyde. T...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1996.tb02246.x
更新日期：1996-06-01 00:00:00
abstract：:A popular "skin protector" consisting of an emulsion-like foam of lipophilic and hydrophilic substances (Marly skin) was evaluated in a previously described repetitive irritation guinea pig model. The product failed to inhibit the irritation due to sodium lauryl sulphate and toluene. In striking contrast to the recomm...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1993.tb03486.x
更新日期：1993-08-01 00:00:00
abstract：:Bullous dermatitis, which resolved leaving hyperpigmentation and which was clinically consistent with phytophotodermatitis , affected the skin of the neck of 2 individuals who wore Hawaiian leis (as neck garlands ) made of the fruits of Pelea anisata . In a Daniels culture plate system portions of the fruits showed ph...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1984.tb00104.x
更新日期：1984-04-01 00:00:00
abstract：BACKGROUND:Adverse drug reactions pose an increasing diagnostic challenge in hospitals and in outpatient clinics. When consecutive or repeated allergic drug eruptions are suspected, patch testing is a useful diagnostic tool for determining the causative drugs. OBJECTIVES:The aim of the study was to identify patient ca...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.12076
更新日期：2013-11-01 00:00:00
abstract：:For more than 50 years, the Draize rabbit skin irritation test has reigned supreme as the regulatory method of choice for the identification of skin irritant chemicals. To date no in vitro alternative test has been validated as an adequate replacement. However, one potential option, to test the endpoint of concern (sk...
journal_title：Contact dermatitis
pub_type： 杂志文章,评审
doi：10.1034/j.1600-0536.2001.045001001.x
更新日期：2001-07-01 00:00:00
abstract：:The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1979.tb04910.x
更新日期：1979-12-01 00:00:00
abstract：:Bibliographic sources for the complex subject of aroma chemicals are reviewed. The references are not comprehensive but are those which we found to be of value in finding out some of the opportunities for contact with a sensitizing chemical compound, cinnamic aldehyde. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1975.tb05310.x
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:The prevalence of body piercing and orthodontic treatment has increased during recent decades. Such changes in lifestyle may influence the occurrence of nickel allergy. OBJECTIVES:The aim of this study was to describe the prevalence of nickel allergy in a Swedish youth population. METHODS:In a cross-sectio...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2007.01257.x
更新日期：2008-02-01 00:00:00
abstract：:The usefulness of a trivalent gold salt, gold trichloride (GTC), was evaluated as a marker of contact allergy to gold. Patients patch test-positive or patch test-negative to gold sodium thiosulfate (GSTS), 13 subjects of each, were patch tested with dilution series of GTC and equimolar concentrations of GSTS. In order...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.0105-1873.2005.00648.x
更新日期：2005-08-01 00:00:00
abstract：BACKGROUND:Cyclic acid anhydrides often cause allergic respiratory diseases, but contact urticaria because of these anhydrides has been considered rare. OBJECTIVE:We describe 21 patients diagnosed with occupational contact urticaria at the Finnish Institute of Occupational Health during the period 1990-2006. METHOD:P...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2009.01526.x
更新日期：2009-04-01 00:00:00
abstract：:Contact urticaria to potato was confirmed by skin testing in a 26-year-old male with atopic dermatitis, birch-pollen rhinoconjunctivitis and a history of immediate finger itching upon handling raw potato. The potato peel was non-reactive. The urticarial reactivity to potato could be transferred by the patient's serum ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1983.tb04315.x
更新日期：1983-03-01 00:00:00
abstract：:Fragrance allergy and hand eczema are both common among dermatological patients. Fragrance mix (FM) and its constituents have a recognized relevance to exposure to fine fragrances and cosmetic products. Based on extensive chemical analysis and database search, a new selection of fragrances was established, including 1...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2003.00133.x
更新日期：2003-06-01 00:00:00
abstract：:The goal of this study was to evaluate biophysically and clinically the hand skin of nurses working in the operating room in comparison with the hand skin of a control group of female administrative employees. 19 nurses and 14 employees were included in this trial. Transepidermal water loss (TEWL) and stratum corneum ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2002.460406.x
更新日期：2002-04-01 00:00:00
