Efficacy of skin barrier creams (II). Ineffectiveness of a popular "skin protector" against various irritants in the repetitive irritation test in the guinea pig.

abstract：:The aim of the study was to assess occupational hazards to the farmer's skin associated with processing thyme (Thymus vulgaris L.). 46 farmers were studied during the threshing of dried thyme. They were questioned about work-related skin problems and examined before and after work. In all persons, serum thyme-specific...

journal_title：Contact dermatitis

authors： Spiewak R,Skorska C,Dutkiewicz J

更新日期：2001-04-01 00:00:00

abstract：:Adverse cutaneous reactions to topically applied olive oil are seldom reported, and positive patch tests to it are mostly regarded as allergic. To evaluate such "positive" patch test reactions, 77 female (mean age: 44 years) and 23 male eczema patients (mean age: 46 years) were prospectively patch tested with freshly ...

journal_title：Contact dermatitis

authors： Kränke B,Komericki P,Aberer W

更新日期：1997-01-01 00:00:00

abstract：:In a multicentre study of the German Contact Dermatitis Research Group, sodium lauryl sulfate (SLS) 0.25% and 0.5% aq. has been added to routine allergen patch tests to assess its properties as a convenient diagnostic indicator of individual susceptibility to irritation at the time of patch testing. Previous studies i...

journal_title：Contact dermatitis

authors： Uter W,Geier J,Becker D,Brasch J,Löffler H

更新日期：2004-11-01 00:00:00

abstract：:Many factors can influence the elicitation of hypersensitivity reactions in guinea pigs and humans. The effect which the vehicle might have on the test response in guinea pigs sensitized with various acrylic compounds, using the "guinea pig maximization test", has been investigated. A marked decrease in the number of ...

journal_title：Contact dermatitis

authors： Björkner B,Niklasson B

更新日期：1984-11-01 00:00:00

abstract：:During the 2-year period 1976--1977, seven patients were studied with primary irritant dermatitis from topical preparations containing clioquinol. During the same period contact hypersensitivity to the compound was recorded in 35 eczema patients. Six of the seven patients with clioquinol irritancy had used creams cont...

journal_title：Contact dermatitis

authors： Kero M,Hannuksela M,Sothman A

更新日期：1979-03-01 00:00:00

abstract：:Sensitization to olive oil is seldom reported in the literature. By use of epicutaneous tests a delayed type of hypersensitivity to pure freshly-prepared olive oil could be demonstrated in two patients. Patch tests with certain major constituents of olive oil; the methyl ester of linoleic acid, the glyceryl ester of p...

journal_title：Contact dermatitis

authors： van Joost T,Smitt JH,van Ketel WG

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Common pesticides used in the region by agricultural workers may cause contact allergy. METHODS:Thirty agricultural workers with a history of pesticide exposure and dermatitis involving the face, neck, trunk or extremities, and 20 controls comprising 2 groups of 10 subjects each, group 1 with dermatitis and...

journal_title：Contact dermatitis

authors： Sharma A,Mahajan VK,Mehta KS,Chauhan PS,Sharma V,Sharma A,Wadhwa D,Chauhan S

更新日期：2018-10-01 00:00:00

abstract：:The quantitative risk assessment (QRA) paradigm has been extended to evaluating the risk of induction of allergic contact dermatitis from consumer products. Sensitization QRA compares product-related, topical exposures to a safe benchmark, the sensitization reference dose. The latter is based on an experimentally or c...

journal_title：Contact dermatitis

authors： Farage MA,Bjerke DL,Mahony C,Blackburn KL,Gerberick GF

更新日期：2003-09-01 00:00:00

abstract：:202 patients, 68 males and 134 females, with patch-test-negative, symmetrical vesicular hand eczema were challenged orally in a controlled study with 2.5 mg nickel, 2.5 mg chromium and 1 mg cobalt given as salts of the respective metals. Initially a mixture of the 3 metal salts was given, and if this produced a flare ...

journal_title：Contact dermatitis

authors： Veien NK,Hattel T,Justesen O,Nørholm A

更新日期：1983-09-01 00:00:00

abstract：:The dose- and time-related effect of sodium lauryl sulfate (SLS) on in vitro percutaneous penetration was studied using 3 radiolabeled tracer compounds with different physicochemical properties: tritiated water, hydrocortisone and nickel. Human cadaver abdominal skin from caucasian women was used as membrane in static...

journal_title：Contact dermatitis

authors： Frankild S,Andersen KE,Nielsen GD

更新日期：1995-06-01 00:00:00

abstract：:2 groups of patients were patch tested with a standard series of allergens. 1 group of 159 individuals aged 24-44 years had a history of severe atopic dermatitis, and the other group of 130 individuals in the same age range, had had moderate atopic dermatitis in childhood. In group 1, positive reactions were recorded ...

journal_title：Contact dermatitis

authors： Rystedt I

更新日期：1985-07-01 00:00:00

abstract：:The expression of surface-bound immunoglobulin E by dendritic cells within cutaneous tissue has been compared in atopic and contact dermatitis. 45 patients were recruited into 4 groups using clinical criteria and patch testing to a standard series of allergens: atopic (12 cases), allergic contact dermatitis (14 cases)...

journal_title：Contact dermatitis

authors： Ward KA,Todd D,Thornton C,Walsh M,Burrows D

更新日期：1991-08-01 00:00:00

abstract：:It has been known since the 1940s that nail polishes contain allergenic ingredients. The aim of this study was to clarify whether the nail polishes on the market today contain significant amounts of allergens, and what the solvents are. The following ingredients were determined: toluene, toluene sulfonamide formaldehy...

journal_title：Contact dermatitis

authors： Sainio EL,Engström K,Henriks-Eckerman ML,Kanerva L

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Adverse drug reactions pose an increasing diagnostic challenge in hospitals and in outpatient clinics. When consecutive or repeated allergic drug eruptions are suspected, patch testing is a useful diagnostic tool for determining the causative drugs. OBJECTIVES:The aim of the study was to identify patient ca...

journal_title：Contact dermatitis

authors： Liippo J,Pummi K,Hohenthal U,Lammintausta K

更新日期：2013-11-01 00:00:00

abstract：:The literature is reviewed for contact dermatitis associated with transdermal therapeutic systems. Clonidine, nitroglycerin, scopolamine, estradiol and testosterone are utilized in such applications, and fentanyl is under investigation. Most cutaneous reactions are limited to localized dermatitis; however, generalized...

journal_title：Contact dermatitis

authors： Holdiness MR

更新日期：1989-01-01 00:00:00

abstract：:Toys are a reflection of the compounds used frequently in manufacturing. Allergic contact dermatitis to potties, metal toys, and children's jewelry is well known, however, there is a broad range of skin risks in toys. With the objective to identify and publicize the associated risk of contact dermatitis in children's ...

journal_title：Contact dermatitis

authors： Fenner J,Hadi A,Yeh L,Silverberg N

更新日期：2020-05-01 00:00:00

abstract：:We showed earlier that most patients with contact dermatitis due to corticosteroids show cross-reactions when patch tested with hydrocortisone-17-butyrate (H-17-B). To test whether H-17-B could be used for detecting topical corticosteroid allergy, we screened patients undergoing routine patch testing with H-17-B. Pati...

journal_title：Contact dermatitis

authors： Reitamo S,Lauerma AI,Förström L

更新日期：1989-09-01 00:00:00

abstract：:Musk ambrette has become one of the commonest photosensitizers in many countries and is the cause of persistent light reactions in many patients. A simple method is presented for qualitative analysis for musk ambrette and other nitromusks in colognes using thin-layer chromatography with toluene as carrier solvent and ...

journal_title：Contact dermatitis

authors： Goh CL,Kwok SF

更新日期：1986-01-01 00:00:00

abstract：:Between 1995 and 1999, 1986 patients were tested in the 31 participating centres of the Information Network of Departments of Dermatology (IVDK), all of them members of the German Contact Dermatitis Research Group, with a textile dyes series containing Disperse Blue (DB) 106 and 124, and since 1997 also with a mix of ...

journal_title：Contact dermatitis

authors： Uter W,Geier J,Lessmann H,Hausen BM,IVDK and the German Contact Dermatitis Research Grooup. Information Network of Departments of Dermatology.

更新日期：2001-03-01 00:00:00

abstract：:Several factors may be responsible for stomatitis in general and the burning mouth syndrome in particular. The results of patch testing are reported in 4 patients with burning mouth symptoms thought to be due to sensitization to denture material. 2 patients reacted to substances in Luxene dentures, but the allergens w...

journal_title：Contact dermatitis

authors： van Joost T,van Ulsen J,van Loon LA

更新日期：1988-02-01 00:00:00

abstract：:Tween 80 is an ethoxylated hydrophilic non-ionic surfactant, which is used for the preparation of oil-in-water emulsions in pharmaceutical products, cosmetics, and industrial detergents. Ethoxylated surfactants are polyethers and are thus easily oxidized by atmospheric oxygen to a variety of hydroperoxides, peroxides ...

journal_title：Contact dermatitis

authors： Bergh M,Magnusson K,Nilsson JL,Karlberg AT

更新日期：1997-07-01 00:00:00

abstract：:A cohort of initially 111 office apprentices was prospectively followed for the duration of their training (2 and 3 years, respectively). The point prevalence of (slight) irritant or atopic hand eczema was 18.9% in the initial and 25.0% in the final examinations. Altogether, 37 cases of (slight) hand eczema were noted...

journal_title：Contact dermatitis

authors： Uter W,Pfahlberg A,Gefeller O,Schwanitz HJ

更新日期：1998-02-01 00:00:00

abstract：:Common emulsifiers were tested in over 1,200 patients with eczema. Triethanolamine stearate tested at 5% in petrolatum caused irritant reactions in 9.5% of the patients. On the other hand, non-ionic emulsifying agents tested at 10-20% produced irritation in only a few cases. Allergic reactions were found in 2.1% of th...

journal_title：Contact dermatitis

authors： Hannuksela M,Kousa M,Pirilä V

更新日期：1976-08-01 00:00:00

abstract：:Generalized dermatitis due to trichloroethylene is rare. A 21-year-old printer developed exfoliative dermatitis with mucous membrane involvement, fever and liver dysfunction after a 2-week occupational exposure to trichloroethylene. Positive patch-test reactions to trichloroethylene and to one of its metabolites, tric...

journal_title：Contact dermatitis

authors： Nakayama H,Kobayashi M,Takahashi M,Ageishi Y,Takano T

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis caused by leather is common, and several responsible allergens, such as tanning agents, glues, mercaptobenzothiazole derivatives, and dyes, but also antimicrobials and antifungals, are involved. MATERIAL AND METHODS:Three female patients were referred to the Departments of Dermat...

journal_title：Contact dermatitis

authors： Herman A,Goossens A,Tennstedt D,Bergendorff O,Isaksson M,Mowitz M,Baeck M

更新日期：2019-10-01 00:00:00

abstract：:To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'. ...

journal_title：Contact dermatitis

authors： Thyssen JP,Giménez-Arnau E,Lepoittevin JP,Menné T,Boman A,Schnuch A

更新日期：2012-04-01 00:00:00

abstract：:A patient was found to have a delayed positive patch test to hydrocortisone on multiple testing. This proved to be due to a photoallergy with an action spectrum in the UV-A range. The patient coincidently had a polymorphous light eruption in the UV-B range. ...

journal_title：Contact dermatitis

authors： Rietschel RL

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:The former 'EU Nickel Directive' and, since 2009, the REACH Regulation (item 27 of Annex XVII) do not include all metallic objects. The nickel content of tools is not regulated by the REACH Regulation, even if they may come into in prolonged contact with the skin. Tools might be possible sources of nickel an...

journal_title：Contact dermatitis

authors： Kickinger-Lörsch A,Bruckner T,Mahler V

更新日期：2015-11-01 00:00:00

abstract：:Thirty-six of 37 veterinary surgeons with incapacitating dermatitis had allergic contact dermatitis, mainly from antibiotics such as spiramycin, Penethamate BP and tylosin. Eight were sensitive to rubber materials. Twenty of 36 had positive prick or scratch tests, mainly to animal hair. The atopic sensitivities were r...

journal_title：Contact dermatitis

authors： Hjorth N,Roed-Petersen J

更新日期：1980-01-01 00:00:00

abstract：:Machinists and machine maintenance men working in the metal industry use metal-working fluids capable of causing irritant and allergic contact dermatitis. The objectives of this study were to find out the frequency of skin symptoms in machinists and machine maintenance men (metal workers) and to compare the risk of th...

journal_title：Contact dermatitis

authors： Suuronen K,Jolanki R,Luukkonen R,Alanko K,Susitaival P

更新日期：2007-10-01 00:00:00