Abstract:
:Contact urticaria to potato was confirmed by skin testing in a 26-year-old male with atopic dermatitis, birch-pollen rhinoconjunctivitis and a history of immediate finger itching upon handling raw potato. The potato peel was non-reactive. The urticarial reactivity to potato could be transferred by the patient's serum in a Prausnitz-Küstner test, indicating an immunological etiology. Electrophoretic and chromatographic examination of extracts from homogenized potatoes (unexposed to synthetic fertilizers and insecticides) revealed allergenic activity in a heat-labile macromolecular fraction with a mass of 20-30 kdalton migrating towards the anode during agarose gel electrophoresis at pH 8.6 with a mobility similar to that of human alpha 1-antitrypsin. The technique used for preliminary fractionation of the allergenic activity in a potato extract, similar to crossed immunoelectrophoresis, appears to be a simple and widely applicable technique for the characterization of proteins with this biological activity. A partially purified fraction with allergenic activity, seemingly more stable than the activity in crude homogenates, was obtained by gel filtration and preparative agarose gel electrophoresis. When an antihistamine was also injected, the urticarial reaction to the protein fraction was less pronounced. Pretreatment of the skin with compound 48/80, a histamine releaser, blocked the reaction. Histamine thus seems to be the major vasoactive substance mediating the contact urticarial response to potato antigen in this patient.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Larkò O,Lindstedt G,Lundberg PA,Mobacken Hdoi
10.1111/j.1600-0536.1983.tb04315.xsubject
Has Abstractpub_date
1983-03-01 00:00:00pages
108-14issue
2eissn
0105-1873issn
1600-0536journal_volume
9pub_type
杂志文章abstract::Retesting with an allergen at a site with previous allergic contact dermatitis has been shown to enhance reactivity. It has been suggested that retesting with a cross-reactive allergen will also induce hyperreactivity. Concurrent sensitization to more than 1 thiuram is common, but whether this is due to concomitant pr...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2006.00785.x
更新日期:2006-03-01 00:00:00
abstract::Data on 134 consecutive nickel-sensitive subjects attending our contact dermatitis clinic were analysed. The female to male ratio was 8 to 1, with a mean age at presentation of 35 years for women and 53 years for men. Hand dermatitis occurred in 49% of patients and in 70% of men. It was usually preceeded by jewellery ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1986.tb01198.x
更新日期:1986-03-01 00:00:00
abstract::Skin protection measures - barrier creams, protective gloves - and skin care are widely recommended for the prevention of occupational hand dermatitis (HD) in skin risk professions, but there is hardly anything known about uptake levels of the measures. The objective of this controlled intervention study was to quanti...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2002.460204.x
更新日期:2002-02-01 00:00:00
abstract::Contact allergy to corticosteroids now seems frequent among patients being patch tested. As corticosteroids are intrinsically anti-inflammatory, we investigated whether patch tests with a potent corticosteroid might suppress simultaneous adjacent patch test reactions to another allergen. Nickel-sensitive subjects were...
journal_title:Contact dermatitis
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0536.1995.tb00809.x
更新日期:1995-03-01 00:00:00
abstract::In 1988, 64% of our patients patch test positive to at least 1 allergen of the ICDRG standard series were nickel sensitive. In 70% of 300 patients evaluated, dermatitis started on the earlobes and was related to the regular wearing of cheap earrings. At the same time, 62% of 735 young schoolgirls were found to have de...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb03203.x
更新日期:1989-10-01 00:00:00
abstract::Metallic aluminium and methylene blue applied to human skin interact and give a strong resistant coloration, obtained neither with methylene blue itself nor with other dyes. The reaction proves that aluminium is not an inert material and that the aluminium in Finn chambers can be expected to interact with other patch ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1985.tb01031.x
更新日期:1985-01-01 00:00:00
abstract::We report the results of scarified photopatch testing in 3 patients with photosensitivity to lomefloxacin, a new quinolone antibacterial agent introduced onto the Japanese market in April 1990. The patients developed pruritic eczematous lesions on sun-exposed areas 5 days to 3 weeks after they had started taking lomef...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1992.tb00860.x
更新日期:1992-01-01 00:00:00
abstract::A 30-year-old male developed asthma and pruritus after using an insecticidal spray (Pyrex). The same symptoms appeared with an alcoholic skin disinfectant (M-sprit) and other spirituous preparations denaturated with denatonium benzoate (Bitrex). An open epicutaneous test (20 min) showed wheal and erythema to Pyrex, M-...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1980.tb05568.x
更新日期:1980-12-01 00:00:00
abstract::An outbreak of occupational dermatitis in an electroforming plant where there was heavy exposure to nickel is described. Patch test investigations confirmed nickel allergy in 13 of 27 exposed individuals. Nickel chloride was found to be a more reliable patch test allergen than nickel sulphate. Improvements in industri...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1980.tb04985.x
更新日期:1980-10-01 00:00:00
abstract::3 patients with contact dermatitis to an ethyl cyanoacrylate glue are presented. Although reactions to cyanoacrylate glues are considered rare, more widespread use of these products by nail salons is likely to be associated with an increased incidence of positive reactions. All 3 of our patients came into contact with...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1987.tb02719.x
更新日期:1987-10-01 00:00:00
abstract::1310 patients were routinely patch tested with a paratertiary-butylphenol-formaldehyde resin (PTBP-F-R), a resol resin based on phenol and formaldehyde (P-F-R-2), and a mixture of these 2 resins. Approximately 2.5 times more patients with contact allergy to phenol-formaldehyde resins were diagnosed when routinely patc...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1988.tb05507.x
更新日期:1988-08-01 00:00:00
abstract::A cohort of initially 111 office apprentices was prospectively followed for the duration of their training (2 and 3 years, respectively). The point prevalence of (slight) irritant or atopic hand eczema was 18.9% in the initial and 25.0% in the final examinations. Altogether, 37 cases of (slight) hand eczema were noted...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
abstract::Cheilitis granulomatosa (CG) is a rare disorder of unknown origin, which is characterized clinically by painless, recurrent or persistent swelling of 1 or both lips. Betel quids, composed of betel nuts (seeds of the Areca catechu), slake lime, and Piper betel leaf/or Piper betel inflorescence, are widely used in Asia ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2007.01269.x
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Contact allergy to epoxy (meth)acrylates, 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (bis-GMA), 2,2-bis[4-(2-hydroxy-3-acryloxypropoxy)phenyl]-propane (bis-GA), 2,2-bis[4-(methacryl-oxyethoxy)phenyl] propane (bis-EMA), 2,2-bis[4-(methacryloxy)phenyl]-propane (bis-MA), and glycidyl methacrylat...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2009.01574.x
更新日期:2009-07-01 00:00:00
abstract::The consequences of a diagnosis of occupational contact dermatitis (OCD) were investigated using cases available from the voluntary surveillance scheme, EPIDERM. Cases of OCD reported from November 1994 to September 1995 were identified and sampled to give at least 100 cases of allergic, irritant and mixed OCD reporte...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2002.460505.x
更新日期:2002-05-01 00:00:00
abstract::To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'. ...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.2011.02004_2.x
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Nickel is the most common cause of contact allergy and an important risk factor for hand eczema. Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel. OBJECTIVES:To develop and evaluate methods for visualization of ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2010.01856.x
更新日期:2011-03-01 00:00:00
abstract::A 59-year-old saleswoman of black hats presented with a severe purpuric eruption of the exposed areas of the face, neck and arms. Patch testing to paraphenylenediamine produced a purpuric test reaction. Similar eruptions have been reported due to N-isopropyl-N-phenylparaphenylenediamine (IPPD), a rubber antioxidant. T...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1978.tb03793.x
更新日期:1978-08-01 00:00:00
abstract::Risk factors for cement eczema were studied among workers employed in the Danish construction industry. 2 cohorts exposed to cement containing different concentrations of water-soluble chromate were examined. A statistically significant decrease in the number of workers with allergic cement eczema was found in the coh...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1991.tb01793.x
更新日期:1991-08-01 00:00:00
abstract::Results concerning 1,000 cases of contact dermatitis with positive patch tests are presented. The allergens which are responsible for about 50% of our cases are: turpentine, nickel, hexavalent chromium and organic mercurial compounds. These results are compared with those of other countries. As in the industrial world...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05385.x
更新日期:1975-08-01 00:00:00
abstract::Bibliographic sources for the complex subject of aroma chemicals are reviewed. The references are not comprehensive but are those which we found to be of value in finding out some of the opportunities for contact with a sensitizing chemical compound, cinnamic aldehyde. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05310.x
更新日期:1975-01-01 00:00:00
abstract::The quantitative risk assessment (QRA) paradigm has been extended to evaluating the risk of induction of allergic contact dermatitis from consumer products. Sensitization QRA compares product-related, topical exposures to a safe benchmark, the sensitization reference dose. The latter is based on an experimentally or c...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2003.00192.x
更新日期:2003-09-01 00:00:00
abstract::Some methacrylates are known to be strong contact sensitizers. To determine the effect of side-chain length on sensitizing potential, we examined 11 derivatives with linear side chains from C1 to C18 in an experimental sensitization test in guinea pigs. The results showed an increase in the sensitizing potential with ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1999.tb05971.x
更新日期:1999-01-01 00:00:00
abstract::High frequencies of contact allergy to fragrance ingredients have been reported in recent years. Only approximately 70-80% are detected by fragrance allergens in the standard patch test series. This investigation compares the patch test reactions to fine fragrances with reactions to fragrance mix (FM), balsam of Peru ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2003.0264.x
更新日期:2003-12-01 00:00:00
abstract::As part of the investigation of sources of exposure to rosin allergens, disposable diapers (napkins) common on the Swedish market were analyzed, using gas chromatography, to detect the main rosin compounds. Rosin components were detected in all diapers, the highest amounts in those from the 2 major producers. In these...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02169.x
更新日期:1996-03-01 00:00:00
abstract::The purpose of this study was to investigate the role of contact hypersensitivity (CHS) in adult widespread eczema (WE) and to analyse the aetiology of WE. 108 consecutive adult WE patients were patch tested. 352 patients with suspected localized allergic contact dermatitis (ACD) tested in the same period served as a ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2002.470605.x
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Reviews on irritant and allergic airborne contact dermatitis have been previously reported in the literature. MATERIALS AND METHODS:Here, we present an update based on recently published airborne-induced skin reactions. For this survey, we screened the journals Contact Dermatitis, Dermatitis, and included r...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/cod.12022
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases. OBJECTIVES:To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols and/or Amerchol™ L-101)...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12872
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The use of permanent hair dyes exposes hairdressers to contact allergens such as p-phenylenediamine (PPD), and the preventive measures are insufficient. OBJECTIVES:To perform an in vivo test to study the protective effect of gloves commonly used by hairdressers. PATIENTS/MATERIALS/METHODS:Six gloves from S...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12320
更新日期:2015-04-01 00:00:00
abstract::3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method. All 3 resin acids were almost negative. The commercial products gave different results. While the maleic-modified product of Greek origin showed a strong s...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1990.tb03229.x
更新日期:1990-08-01 00:00:00