Abstract：
:Data on 134 consecutive nickel-sensitive subjects attending our contact dermatitis clinic were analysed. The female to male ratio was 8 to 1, with a mean age at presentation of 35 years for women and 53 years for men. Hand dermatitis occurred in 49% of patients and in 70% of men. It was usually preceeded by jewellery or metal contact dermatitis for some months or years. Although office workers made up the largest occupational group, cleaners, housewives, catering staff, nurses and hairdressers were represented among the women. Several of the men had had heavy occupational exposure to nickel. Cobalt co-sensitivity occurred in 29% of subjects. Sensitivity to 3 or more allergens was found in 32% of those studied but was seen in 2/3 of the men. The prevalence of a personal history of atopy was not raised. A majority of women had had their ears pierced: in 2/3 the nickel dermatitis followed this procedure but in a third it had occurred before. Female sex, jewellery contact and wetwork occupations all predispose to the development of nickel sensitivity.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Gawkrodger DJ,Vestey JP,Wong WK,Buxton PKdoi
10.1111/j.1600-0536.1986.tb01198.xsubject
Has Abstractpub_date
1986-03-01 00:00:00pages
165-9issue
3eissn
0105-1873issn
1600-0536journal_volume
14pub_type
杂志文章abstract：:This is a study of occupational skin disease among military personnel and conscripts in Singapore. All military personnel and conscripts diagnosed with occupational dermatoses in the National Skin Centre, Singapore, between 1989-1999 were studied retrospectively. Conscripts and regulars comprised 7.3% of all occupatio...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2001.440206.x
更新日期：2001-02-01 00:00:00
abstract：:The frequency of positive patch tests to 13 rubber accelerators in Poland was recorded. Of particular interest was the relatively large group of patients positive to several, mostly chemically unrelated, accelerators. The mechanism of this multiple sensitivity is discussed. Positive tests to N-isopropyl-N-phenyl-p-phe...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1976.tb02974.x
更新日期：1976-02-01 00:00:00
abstract：:A dermatologic investigation of 202 construction painters included patch testing with the TRUE Test standard series and ingredients of water-based paints, glues and putties (painters' series). 32 painters had current eczema and 16 had a history of previous eczema. Of these, 16 and 9, respectively, had current and prev...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1995.tb00839.x
更新日期：1995-01-01 00:00:00
abstract：:Skin protection measures - barrier creams, protective gloves - and skin care are widely recommended for the prevention of occupational hand dermatitis (HD) in skin risk professions, but there is hardly anything known about uptake levels of the measures. The objective of this controlled intervention study was to quanti...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2002.460204.x
更新日期：2002-02-01 00:00:00
abstract：:According to some reports in the literature, the hormonal fluctuations which occur during the menstrual cycle may affect the clinical expression of contact allergy to a greater or lesser degree. In clinical practice, too, patient history often shows exacerbation of the contact dermatitis during the days immediately pr...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.0105-1873.2005.00588.x
更新日期：2005-06-01 00:00:00
abstract：:In 1988, 64% of our patients patch test positive to at least 1 allergen of the ICDRG standard series were nickel sensitive. In 70% of 300 patients evaluated, dermatitis started on the earlobes and was related to the regular wearing of cheap earrings. At the same time, 62% of 735 young schoolgirls were found to have de...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1989.tb03203.x
更新日期：1989-10-01 00:00:00
abstract：:Between 1995 and 1999, 1986 patients were tested in the 31 participating centres of the Information Network of Departments of Dermatology (IVDK), all of them members of the German Contact Dermatitis Research Group, with a textile dyes series containing Disperse Blue (DB) 106 and 124, and since 1997 also with a mix of ...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究
doi：10.1034/j.1600-0536.2001.044003173.x
更新日期：2001-03-01 00:00:00
abstract：:Acute irritant contact dermatitis (ICD) is frequently treated with cool water or saline compresses. While presumed effective, little quantitative evaluation documents the treatment's benefit. This study sought to determine the efficacy of both distilled water and physiologic saline compresses on experimentally-induced...
journal_title：Contact dermatitis
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1600-0536.2001.045003146.x
更新日期：2001-09-01 00:00:00
abstract：:A 59-year-old saleswoman of black hats presented with a severe purpuric eruption of the exposed areas of the face, neck and arms. Patch testing to paraphenylenediamine produced a purpuric test reaction. Similar eruptions have been reported due to N-isopropyl-N-phenylparaphenylenediamine (IPPD), a rubber antioxidant. T...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1978.tb03793.x
更新日期：1978-08-01 00:00:00
abstract：:The development of topical drug products requires testing for skin toxicology reactions. A variety of patch test systems are available with which chemicals are applied to skin. The purpose of this study was to determine the skin absorption of paraphenylenediamine (PPDA) from a variety of such systems. [14C]-PPDA (1% p...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1987.tb02701.x
更新日期：1987-09-01 00:00:00
abstract：:The validity of questionnaire answers with respect to hand eczema was investigated. Car mechanics, dentists and office workers answered a questionnaire on the occurrence of hand eczema on any occasion during the past 12 months. "Yes"-responders and a random sample of "no"-responders were subsequently interviewed and e...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2001.045002099.x
更新日期：2001-08-01 00:00:00
abstract：:Deodorants are one of the most frequently-used types of cosmetics and are a source of allergic contact dermatitis. Therefore, a gas chromatography - mass spectrometric analysis of 71 deodorants was performed for identification of fragrance and non-fragrance materials present in marketed deodorants. Futhermore, the sen...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1998.tb05944.x
更新日期：1998-12-01 00:00:00
abstract：:1310 patients were routinely patch tested with a paratertiary-butylphenol-formaldehyde resin (PTBP-F-R), a resol resin based on phenol and formaldehyde (P-F-R-2), and a mixture of these 2 resins. Approximately 2.5 times more patients with contact allergy to phenol-formaldehyde resins were diagnosed when routinely patc...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1988.tb05507.x
更新日期：1988-08-01 00:00:00
abstract：:For more than 50 years, the Draize rabbit skin irritation test has reigned supreme as the regulatory method of choice for the identification of skin irritant chemicals. To date no in vitro alternative test has been validated as an adequate replacement. However, one potential option, to test the endpoint of concern (sk...
journal_title：Contact dermatitis
pub_type： 杂志文章,评审
doi：10.1034/j.1600-0536.2001.045001001.x
更新日期：2001-07-01 00:00:00
abstract：:The aim of the study was to assess occupational hazards to the farmer's skin associated with processing thyme (Thymus vulgaris L.). 46 farmers were studied during the threshing of dried thyme. They were questioned about work-related skin problems and examined before and after work. In all persons, serum thyme-specific...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2001.044004235.x
更新日期：2001-04-01 00:00:00
abstract：:A patient was found to have a delayed positive patch test to hydrocortisone on multiple testing. This proved to be due to a photoallergy with an action spectrum in the UV-A range. The patient coincidently had a polymorphous light eruption in the UV-B range. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1978.tb03845.x
更新日期：1978-12-01 00:00:00
abstract：:Thirty-six of 37 veterinary surgeons with incapacitating dermatitis had allergic contact dermatitis, mainly from antibiotics such as spiramycin, Penethamate BP and tylosin. Eight were sensitive to rubber materials. Twenty of 36 had positive prick or scratch tests, mainly to animal hair. The atopic sensitivities were r...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1980.tb03885.x
更新日期：1980-01-01 00:00:00
abstract：:To study the frequency of sensitization to 26 fragrances to be labelled according to current European regulation. During 4 periods of 6 months, from 1 January 2003 to 31 December 2004, 26 fragrances were patch tested additionally to the standard series in a total of 21 325 patients; the number of patients tested with ...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究,评审
doi：10.1111/j.1600-0536.2007.01088.x
更新日期：2007-07-01 00:00:00
abstract：:Although hand hygiene is an important and inexpensive measure to prevent nosocomial infections in clinical settings, the compliance of healthcare workers remains low. In Europe, alcoholic hand disinfection is first choice, but there exists a limited user acceptability due to estimated adverse effects on skin condition...
journal_title：Contact dermatitis
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.0105-1873.2006.00817.x
更新日期：2006-05-01 00:00:00
abstract：:Little is known about the prognosis of facial allergic contact dermatitis (FACD). The objective of the study was to investigate the prevalence and 1-year outcome of FACD in patients patch tested. 655 consecutive patients patch tested with European standard series in Peking University Hospital in a 2-year period were s...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2007.01198.x
更新日期：2007-09-01 00:00:00
abstract：:Protein kinase C (PKC) isoforms are important in cell signal transduction associated with regulation of cell proliferation and differentiation. In this study, alterations of PKC isoform levels in irritant patch test reactions were detected by Western immunoblots. 4 chemically and structurally different irritants, 4% a...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1998.tb05766.x
更新日期：1998-06-01 00:00:00
abstract：:In an evaluation of the safety of new chemicals, of products containing them, or of novel formulations of existing chemicals which may come into contact with the skin, it is important to incorporate an assessment of specially susceptible sub-populations. Such a group is represented by those who are more likely to expe...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1993.tb03534.x
更新日期：1993-10-01 00:00:00
abstract：:Japanese lacquer is made from the sap of the Japanese lacquer tree (Toxicodendron vernicifluum), a member of the Anacardiacae plant family. Objects painted with this material are described collectively as lacquerware. Both fresh lacquer and lacquerware may evoke allergic contact reactions ascribable to the urushiols c...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1992.tb03254.x
更新日期：1992-10-01 00:00:00
abstract：:8 cases of contact dermatitis from toluenesulfonamide formaldehyde resin in a nail hardener are presented. Most patients had used nail lacquers containing this resin for many years without trouble, but became sensitized to the resin shortly after the introduction of this particular nail hardener. A hypothesis concerni...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1988.tb02833.x
更新日期：1988-05-01 00:00:00
abstract：:Plants from the Verbenaceae family may cause contact dermatitis of unknown nature. This report describes 2 cases of allergic reactions to the Verbena species. A teenage boy developed an anaphylactic allergic response following contact with the leaves of Verbena hybrida. Characterization of the patient's specific IgE r...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1995.tb02049.x
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:Wheat protein and its derivatives can cause protein contact dermatitis (PCD), which mainly occurs in bakers. Few studies have attempted to identify the allergens responsible for wheat PCD. OBJECTIVES:The aim of this study was to identify allergenic wheat proteins in patients with wheat PCD. METHODS:Water-s...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2010.01741.x
更新日期：2010-07-01 00:00:00
abstract：:3-Iodo-2-propynyl-butylcarbamate (IPBC) is a fungicide used in both industrial products and cosmetics. We report the first case of allergic contact dermatitis from airborne exposure to this preservative. A 34-year-old female production worker at a paint factory developed dermatitis on air-exposed skin areas. Patch tes...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2003.00079.x
更新日期：2003-03-01 00:00:00
abstract：:The allergenicity and the cross-reactivity of naphthenic acid (NA) and its metallic salts were evaluated in experimental animals. In the guinea pig maximization test, sensitizing skin reactions were observed with cobalt naphthenate (CoN), zinc naphthenate (ZnN) and NA, but not with copper naphthenate, with CoN being t...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.0105-1873.2006.00728.x
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Allergic contact dermatitis caused by (meth)acrylates is well known, both in occupational and in non-occupational settings. Contact hypersensitivity to electrocardiogram (ECG) electrodes containing (meth)acrylates is rarely reported. OBJECTIVE:To report the first case of contact dermatitis caused by acrylic...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.12357
更新日期：2015-07-01 00:00:00
abstract：:Guinea pigs were sensitized to dinitrochlorobenzene (DNCB) by the intracutaneous route and challenged epicutaneously on the flanks. The intensity of the allergic contact dermatitis was evaluated by inspection and palpation as well as by wet weight determination. With the purpose of diminishing tissue neuropeptides, an...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1991.tb01626.x
更新日期：1991-01-01 00:00:00
