Capsaicin enhances allergic contact dermatitis in the guinea pig.

Abstract:

:Guinea pigs were sensitized to dinitrochlorobenzene (DNCB) by the intracutaneous route and challenged epicutaneously on the flanks. The intensity of the allergic contact dermatitis was evaluated by inspection and palpation as well as by wet weight determination. With the purpose of diminishing tissue neuropeptides, and substance P in particular, the animals were treated with capsaicin either between induction and challenge, or before sensitization. In comparison with controls, the contact dermatitis was enhanced in both groups of animals treated with capsaicin.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Wallengren J,Ekman R,Möller H

doi

10.1111/j.1600-0536.1991.tb01626.x

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

30-4

issue

1

eissn

0105-1873

issn

1600-0536

journal_volume

24

pub_type

杂志文章
  • Allergic contact dermatitis caused by dexpanthenol-Probably a frequent allergen.

    abstract:BACKGROUND:Panthenol (synonym: dexpanthenol), the alcohol analogue of panthothenic acid, is frequently included in moisturizers, wound-healing agents, and other cosmetics, and has been shown to be responsible for allergic contact dermatitis (ACD). OBJECTIVES:To evaluate the frequency of ACD caused by dexpanthenol, and...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13054

    authors: Fernandes RA,Santiago L,Gouveia M,Gonçalo M

    更新日期:2018-11-01 00:00:00

  • On the lookout for precursor lesions: where does dry skin end and slight hand eczema begin?

    abstract:BACKGROUND:The prognosis of occupational hand eczema is strongly associated with its duration, severity, and the onset of treatment. OBJECTIVES:The study was aimed at characterizing skin eruptions that might be potential precursors of occupational hand eczema, their pattern, and typical sites in a population at modera...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2011.01969.x

    authors: Baumeister T,Uter W,Weistenhöfer W,Drexler H,Kütting B

    更新日期:2012-02-01 00:00:00

  • 10 years' experience of patch testing with a shoe series in 230 patients: which allergens are important?

    abstract::Over a 10-year period, 230 patients with foot dermatitis were patch tested to a shoe series of allergens. About 54 (23%) had relevant allergic positive reactions to one or more allergens. The commonest relevant allergens groups were, in order, chromate, medicaments, rubber chemicals, dyes and cosmetic constituents, wi...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2005.00631.x

    authors: Holden CR,Gawkrodger DJ

    更新日期:2005-07-01 00:00:00

  • Reactions to resin-based dental materials in patients--type, time to onset, duration, and consequence of the reaction.

    abstract:OBJECTIVE:The aim of the present study was to determine the types of side-effects occurring and for how long they lasted in a group of patients with side-effects assessed to be caused by resin-based materials. METHODS:A total of 618 reports were received by the Swedish National Register of Side-Effects to Dental Mater...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2009.01590.x

    authors: Tillberg A,Stenberg B,Berglund A

    更新日期:2009-12-01 00:00:00

  • Hyperkeratotic hand eczema: Eczema or not?

    abstract:BACKGROUND:Hyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology. OBJECTIVE:To investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE. METHODS:Palmar skin biopsies (lesional and perilesional) were ob...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13572

    authors: Politiek K,Loman L,Pas HH,Diercks GFH,Lemmink HH,Jan SZ,van den Akker PC,Bolling MC,Schuttelaar MLA

    更新日期:2020-09-01 00:00:00

  • Occupational allergic contact dermatitis caused by colophonium.

    abstract:BACKGROUND:Colophonium is a common contact allergen that is present not only in household products but also in occupational settings. OBJECTIVES:To describe the sources of occupational exposure to colophonium and the occupations at risk of colophonium allergy. METHODS:We reviewed patch test files from the years 2002 ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13114

    authors: Pesonen M,Suuronen K,Suomela S,Aalto-Korte K

    更新日期:2019-01-01 00:00:00

  • The repeated open application test (ROAT).

    abstract::Repeated open application tests (ROATs) were performed with common ingredients of vehicles in 86 patients with contact dermatitis. The substances were applied twice daily for 7 days to the flexor aspect of the forearm near the cubital fossa, unless dermatitis appeared earlier. Of the patients with a questionable (?+) ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1986.tb01229.x

    authors: Hannuksela M,Salo H

    更新日期:1986-04-01 00:00:00

  • Evaluation of the sensitising potential of 4 polyamines present in technical triethylenetetramine using 2 animal species.

    abstract::Contact sensitivity to 4 polyamines present in technical grade triethylenetetramine was investigated using the 'VAA mouse' assay and the guinea pig maximization test (GPMT). The criteria used to assess sensitivity in the GPMT classed all substances as having the same degree of sensitising potential. The mouse assay ra...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1988.tb04498.x

    authors: Maisey J,Purchase R,Robbins MC,Miller K

    更新日期:1988-03-01 00:00:00

  • Cinnamic aldehyde in toothpaste. 1. Clinical aspects and patch tests.

    abstract::Although cinnamon is known to cause dermatitis in bakers and confectioners, it has only rarely been reported as causing trouble in food or cosmetics. A newly-formulated 'spicy' toothpaste containing cinnamon as a flavouring agent was the cause of oral symptoms in eight patients referred to clinics in Buckinghamshire a...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05330.x

    authors: Magnusson B,Wilkinson DS

    更新日期:1975-01-01 00:00:00

  • Sensitive skin: closing in on a physiological cause.

    abstract::The phenomenon of 'sensitive skin' is a relatively recent complaint in which certain individuals report more intense and frequent adverse sensory effects than the normal population upon use of cosmetic (personal-care) products. Originally defined as a minority complaint, sensitive skin is now claimed by a majority of ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.2009.01697.x

    authors: Farage MA,Maibach HI

    更新日期:2010-03-01 00:00:00

  • Sensitization potential and potency of terpene hydroperoxides in the cocultured activation test method.

    abstract:BACKGROUND:Positive patch test reactions to mixtures of oxidized terpenes containing allergenic hydroperoxides are frequently reported. However, human sensitization data for these hydroperoxides are not available. OBJECTIVES:To analyse and evaluate the human sensitization potential and potency of hydroperoxides in vit...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13286

    authors: Hennen J,Silva E Sousa M,Sahli F,Lichter J,Lepoittevin JP,Giménez-Arnau E,Blömeke B

    更新日期:2019-08-01 00:00:00

  • Allergic and irritant patch test reactions and atopic disease.

    abstract::This study presents a profile of patients with chronic recalcitrant eczematous disease referred by dermatologists for contact allergy evaluation. Allergic contact dermatitis (ACD) and irritant responses were carefully defined, as was the presence or absence of atopy obtained by history. Of 410 patients studied, 44% ha...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02143.x

    authors: Klas PA,Corey G,Storrs FJ,Chan SC,Hanifin JM

    更新日期:1996-02-01 00:00:00

  • Evidence of increased skin irritation after wet work: impact of water exposure and occlusion.

    abstract:BACKGROUND:Exposure to humid environments/water and prolonged glove occlusion are both believed to cause irritant contact dermatitis. OBJECTIVES:To study the effects of different forms of wet work, especially the differences between water exposure and occlusion, by using an experimental model simulating occupational w...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2012.02063.x

    authors: Fartasch M,Taeger D,Broding HC,Schöneweis S,Gellert B,Pohrt U,Brüning T

    更新日期:2012-10-01 00:00:00

  • Reduced frequency of atopic dermatitis in quinoline-allergic patients: the 'hapten-atopy hypothesis'.

    abstract:BACKGROUND:While allergy to food proteins is almost exclusively found in association with atopy, it has been our experience that contact allergy to some contact allergens/haptens with both cutaneous and gastrointestinal exposures is reduced in atopic dermatitis (AD) patients as a group. OBJECTIVE:To assess the contact...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01321.x

    authors: McFadden JP,White JM

    更新日期:2008-05-01 00:00:00

  • Investigation of contact allergy to dental metals in 206 patients.

    abstract:BACKGROUND:Contact allergy to dental materials is poorly understood; clinical manifestations are heterogeneous. OBJECTIVE:To analyse positive patch test reactions to metals (as their alloys or salts) used in dentistry together with clinical symptoms and possible relevance to dental fillings. METHODS:We retrospectivel...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2009.01524.x

    authors: Raap U,Stiesch M,Reh H,Kapp A,Werfel T

    更新日期:2009-06-01 00:00:00

  • Occupational contact dermatitis caused by 1,3-benzenedimethanamine, N-(2-phenylethyl) derivatives in hardeners for epoxy paints and coatings.

    abstract:BACKGROUND:Amines in epoxy hardeners are significant causes of occupational allergic contact dermatitis among workers who use epoxy resin systems. OBJECTIVES:To describe a novel group of contact allergens: N-(2-phenylethyl) derivatives of the reactive amine 1,3-benzenedimethanamine (1,3-BDMA). METHODS:We describe the...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12652

    authors: Pesonen M,Kuuliala O,Suomela S,Aalto-Korte K

    更新日期:2016-12-01 00:00:00

  • Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea.

    abstract:BACKGROUND:An acute viral cold is a very common illness and is characterized by sneezing and a runny nose. Because of rhinorrhea and frequent use of handkerchiefs, the skin around the nose feels uncomfortably dry and flaky. OBJECTIVES/METHODS:To evaluate the nasolabial skin barrier impairment, 14 female volunteers wit...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01425.x

    authors: Houben E,Adam R,Hachem JP,Roseeuw D,Rogiers V,De Paepe K

    更新日期:2008-11-01 00:00:00

  • Bacteria and soluble oil dermatitis.

    abstract::Simultaneous investigation of the bacterial flora of a soluble oil in use as a metalworking fluid and of the skin of machine operatives exposed to that soluble oil did not support the hypothesis that bacteria in soluble oil emulsions colonise the skin and either initiate or maintain the dermatitis associated with solu...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1980.tb03873.x

    authors: Rycroft RJ

    更新日期:1980-01-01 00:00:00

  • Nickel and cobalt release from metal alloys of tools--a current analysis in Germany.

    abstract:BACKGROUND:The former 'EU Nickel Directive' and, since 2009, the REACH Regulation (item 27 of Annex XVII) do not include all metallic objects. The nickel content of tools is not regulated by the REACH Regulation, even if they may come into in prolonged contact with the skin. Tools might be possible sources of nickel an...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12462

    authors: Kickinger-Lörsch A,Bruckner T,Mahler V

    更新日期:2015-11-01 00:00:00

  • Effect of test techniques of perfusion of neomycin sulfate patch tests. A comparative study with visual assessments.

    abstract::Effects of test techniques on neomycin patch test results have not been thoroughly investigated. This study focuses on effects of dose and application time of neomycin sulfate patch tests on test results. The effects are assessed both visually and by perfusion. 16 subjects positive to neomycin are retested with neomyc...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0536.2000.043005283.x

    authors: Bjarnason B,Flosadóttir E

    更新日期:2000-11-01 00:00:00

  • Shiitake (Lentinus edodes) dermatitis.

    abstract::Shiitake (Lentinus edodes) is a mushroom which is eaten in Chinese and Japanese meals and is nowadays the second most commonly produced edible mushroom in the world. Shiitake dermatitis was first described by Nakamura in 1977. This disease presents with very characteristic skin manifestations. From April 1974 to April...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.1992.tb05211.x

    authors: Nakamura T

    更新日期:1992-08-01 00:00:00

  • Occupational contact allergy to cocamidopropyl betaine and its impurities.

    abstract:BACKGROUND:Contact allergy to cocamidopropyl betaine has been attributed to its impurities dimethylaminopropylamine and cocamidopropyl dimethylamine. OBJECTIVES:To describe patients with positive patch test reactions to cocamidopropyl betaine-related compounds in an occupational dermatology clinic. METHODS:We reviewe...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2011.02036.x

    authors: Suuronen K,Pesonen M,Aalto-Korte K

    更新日期:2012-05-01 00:00:00

  • Contact allergy to kojic acid in skin care products.

    abstract::Kojic acid (5-hydroxy-2-(hydroxymethyl)-4-pyrone), a fungal metabolic product, has increasingly been used as a skin-depigmenting agent in skin care products marketed in Japan since 1988. In order to determine its frequency of sensitization, during 1 year from October 1992 to September 1993, we performed patch testing ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1995.tb00832.x

    authors: Nakagawa M,Kawai K,Kawai K

    更新日期:1995-01-01 00:00:00

  • Contact sensitivity to topical antimicrobials. (II). Sensitizing potentials of some topical antimicrobials.

    abstract::A predictive study comparing the sensitizing potentials of some topical antimicrobials, using a modified Beuhler's technique, showed that over-the-counter (OTC) antimicrobials were more sensitizing than prescribed topical antibiotics. Among OTC antimicrobials, proflavine was the most potent sensitizer (4/10 guinea pig...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1989.tb04730.x

    authors: Goh CL

    更新日期:1989-09-01 00:00:00

  • Skin physiological changes in employees in the fish processing industry immediately following work. A field study.

    abstract::In order to explain the complaints of dry skin after work among employees in the fish processing industry, we followed the skin blood flow (SBF), skin surface temperature, transepidermal water loss (TEWL) and electrical capacitance on the volar aspect of the 3rd finger in 10 fillet workers, where measurements were per...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1991.tb01767.x

    authors: Halkier-Sørensen L,Thestrup-Pedersen K

    更新日期:1991-07-01 00:00:00

  • Comparison of in vitro predictive tests for irritation induced by anionic surfactants.

    abstract::Skin compatibility of anionic surfactants may often but not always be predicted by in vitro tests. For instance, the correlation between in vivo and in vitro data is classically hampered in the presence of magnesium. This ion is known to interfere with in vitro skin irritation predictive tests based on protein denatur...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1995.tb00445.x

    authors: Goffin V,Paye M,Piérard GE

    更新日期:1995-07-01 00:00:00

  • Occupational allergic contact dermatitis from cinnamon including one case from airborne exposure.

    abstract:BACKGROUND:The bark of the cinnamon tree is used as a spice; its flavour is from an essential oil containing mainly cinnamal. OBJECTIVE:To report new cases of occupational allergic contact dermatitis (ACD) from cinnamon and a novel case of airborne cinnamon contact allergy. METHODS:We examined the patient material of...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01486.x

    authors: Ackermann L,Aalto-Korte K,Jolanki R,Alanko K

    更新日期:2009-02-01 00:00:00

  • A multicentre review of the hairdressing allergens tested in the UK.

    abstract::Allergens used for patch testing in the hairdressing series vary between dermatology centres in the UK. The aim of our study is to ascertain the hairdressing allergens currently in use and their test results in several dermatology centres in the UK. Data were obtained from databases in 9 dermatology departments. The a...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.0105-1873.2005.00661.x

    authors: Katugampola RP,Statham BN,English JS,Wilkinson MM,Foulds IS,Green CM,Ormerod AD,Stone NM,Horne HL,Chowdhury MM

    更新日期:2005-09-01 00:00:00

  • Sodium metabisulfite--a marker for cosmetic allergy?

    abstract::A 45-year-old woman developed dermatitis of the face after she applied a cosmetic package comprising day and night creams. Patch tests were performed with the British Contact Dermatitis Society (BCDS) standard, bases + preservatives, and cosmetic series in addition to samples of both creams and the individual constitu...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.00972.x

    authors: Malik MM,Hegarty MA,Bourke JF

    更新日期:2007-04-01 00:00:00

  • Identification of pigments related to allergic tattoo reactions in 104 human skin biopsies.

    abstract:BACKGROUND:Red tattoos are prone to allergic reactions. The identity of the allergen(s) is mostly unknown. OBJECTIVES:Chemical analysis of human skin biopsies from chronic allergic reactions in red tattoos to identify culprit pigment(s) and metals. MATERIAL AND METHODS:One hundred four dermatome biopsies were analyze...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13423

    authors: Serup J,Hutton Carlsen K,Dommershausen N,Sepehri M,Hesse B,Seim C,Luch A,Schreiver I

    更新日期:2020-02-01 00:00:00