Abstract：
AIM:To reveal the profile of astragalosides for better quality evaluation of Radix Astragali, this study was aimed to investigate the transformation of astragalosides under different conditions. METHOD:Seven major astragalosides were selected for evaluation under acidic, neutral and alkaline conditions. The transformation in real plant samples was also examined and the products were characterized by LC-ESI-TOF/MS. RESULTS:In weak acidic solution, all of the astragalosides are stable. In addition, the transformation ratios of the astragalosides under neutral and alkaline conditions were also obtained. CONCLUSION:In neutral solution, malonylastragaloside I was transformed to astragaloside I; and in alkaline solution, substituent group(s) in the xylose moiety of all the astragalosides were eliminated. Since astragalosdie IV is the basic skeleton structure of the astrgalosides, it is a common transformation product of other astragalosides.
journal_name
Chin J Nat Medjournal_title
Chinese journal of natural medicinesauthors
Chu C,Liu EH,Qi LW,Li Pdoi
10.1016/S1875-5364(14)60062-5subject
Has Abstractpub_date
2014-04-01 00:00:00pages
314-20issue
4eissn
2095-6975issn
1875-5364pii
S1875-5364(14)60062-5journal_volume
12pub_type
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