Abstract:
:To investigate the non-alkaloidal chemical constituents of the stems and leaves of Melodinus suaveolens and their antibacterial activities. Compounds were isolated and purified by repeated silica gel, Sephadex LH-20, RP18, and preparative HPLC. Their structures were elucidated by comparison with published spectroscopic data, as well as on the basis of extensive spectroscopic analysis. The antibacterial screening assays were performed by the dilution method. Fourteen compounds were isolated, and identified as lycopersene (1), betulinic aldehyde (2), 3β-acetoxy-22,23,24,25,26,27-hexanordammaran-20-one (3), 3a-acetyl-2, 3, 5-trimethyl-7a-hydroxy-5-(4,8,12-trimethyl-tridecanyl)-1,3a,5,6,7,7a-hexahydro-4-oxainden-1-one (4), 3β-hydroxy-28-norlup-20(29)-ene-17β-hydroperoxide (5), 3β-hydroxy-28-norlup-20(29)-ene-17α-hydroperoxide (6), β-sitosterol (7), 28-nor-urs-12-ene-3β, 17β-diol (8), α-amyrin (9), ergosta-4,6,8(14),22-tetraen-3-one (10), 3β-hydroxy-urs-11-en-28,13β-olide (11), betulin (12), obtusalin (13), and ursolic acid (14). Among the isolates, compounds 1, 2, 6, 8, 10, and 14 showed potent antibacterial activities against the four bacteria. This is the first report of the antibacterial activity of the constituents of Melodinus suaveolens.
journal_name
Chin J Nat Medjournal_title
Chinese journal of natural medicinesauthors
Li JL,Lunga PK,Zhao YL,Qin XJ,Yang XW,Liu YP,Luo XDdoi
10.1016/S1875-5364(15)30020-0subject
Has Abstractpub_date
2015-04-01 00:00:00pages
307-10issue
4eissn
2095-6975issn
1875-5364pii
S1875-5364(15)30020-0journal_volume
13pub_type
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(14)60037-6
更新日期:2014-03-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章,评审
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(14)60062-5
更新日期:2014-04-01 00:00:00
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journal_title:Chinese journal of natural medicines
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(13)60079-5
更新日期:2013-11-01 00:00:00
abstract::The phytochemical progress on Angelica sinensis (Oliv.) Diels over the past decades is summarized. Since 1970s, 165 chemical constituents, including phthalides, phenylpropanoids, terpenoids and essential oils, aromatic compounds, alkaloids, alkynes, sterols, fatty acids, and polysaccharides have been isolated or detec...
journal_title:Chinese journal of natural medicines
pub_type: 杂志文章,评审
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(17)30082-1
更新日期:2017-07-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(14)60086-8
更新日期:2014-08-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 历史文章,杂志文章,评审
doi:10.1016/S1875-5364(17)30003-1
更新日期:2017-01-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(14)60052-2
更新日期:2014-04-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 社论
doi:10.1016/S1875-5364(19)30107-4
更新日期:2019-12-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(14)60117-5
更新日期:2014-10-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章,评审
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更新日期:2015-02-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(18)30041-4
更新日期:2018-02-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(15)30097-2
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
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更新日期:2014-05-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(19)30065-2
更新日期:2019-08-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
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更新日期:2016-09-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(16)30059-0
更新日期:2016-07-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(16)30033-4
更新日期:2016-04-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(14)60074-1
更新日期:2014-06-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(14)60027-3
更新日期:2014-03-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章,评审
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更新日期:2020-03-01 00:00:00
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journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.1016/S1875-5364(20)60005-X
更新日期:2020-09-01 00:00:00
abstract::Radix Adenophorae, a traditional Chinese medicine, has been reported to have a variety of biological functions. In the present study, a polysaccharide component, Radix Adenophorae Polysaccharide (RAPS), was purified from Radix Adenophorae by decoloring with ADS-7 macroporous adsorption resin, DEAE-52 cellulose ion-exc...
journal_title:Chinese journal of natural medicines
pub_type: 杂志文章
doi:10.3724/SP.J.1009.2016.00370
更新日期:2016-05-01 00:00:00