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IL-22 gets to the stem of colorectal cancer.

Abstract：

:Cytokines can provide survival and proliferation signals to cancer cells, thus promoting tumor progression. In this issue of Immunity, Kryczek et al. (2014) reveal that interleukin-22 can also promote "stemness" in human colorectal cancer via transcription factor STAT3-mediated epigenetic regulation of stem cell genes.

journal_name

Immunity

journal_title

Immunity

authors

Koltsova EK,Grivennikov SI

doi

10.1016/j.immuni.2014.04.014

subject

Has Abstract

pub_date

2014-05-15 00:00:00

pages

639-41

issue

5

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(14)00152-6

journal_volume

40

pub_type

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