CD28 superagonists: what makes the difference in humans?

Abstract:

:In 2006, a clinical trial with the CD28 superagonistic antibody TGN1412 in London turned into a catastrophe. Studies are beginning to unravel the difference between the human and preclinical animal response to the antibody.

journal_name

Immunity

journal_title

Immunity

authors

Schraven B,Kalinke U

doi

10.1016/j.immuni.2008.04.003

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

591-5

issue

5

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(08)00191-X

journal_volume

28

pub_type

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