Abstract:
:Enzymatic polymerization can offer metal-free routes to polymer materials that could be used in biomedical applications. To take advantage of the unique properties of ionic liquids (ILs) for enzyme stability, monocationic ionic liquid (MIL) and dicationic ionic liquid (DIL) were used to promote the ring-opening polymerization of ε-caprolactone (ε-CL) using Candida antarctica lipase B as catalyst. Considering the molecular weight (M n ) and reaction yield of the resulting polymer (PCL), high density and viscosity of ILs would be good, especially in the case of DIL. With the same total alkyl chain length, the density and viscosity of [C4(C6Im)2][PF6]2 were higher than that of [C12MIm][PF6]. Using a lipase/CL/ILs ratio of 1:20:20 (by wt) for 48 h at 90 °C, the highest M n and reaction yield of PCL were 26,200 g/mol and 62 % with [C4(C6Im)2][PF6]2, while the M n and reaction yield of PCL obtained in [C12MIm][PF6] were 11,700 g/mol and 37 %.
journal_name
Biotechnol Lettjournal_title
Biotechnology lettersauthors
Wu C,Zhang Z,He F,Zhuo Rdoi
10.1007/s10529-013-1160-3subject
Has Abstractpub_date
2013-06-01 00:00:00pages
879-85issue
6eissn
0141-5492issn
1573-6776journal_volume
35pub_type
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