Increased PELP1 expression in rat periodontal ligament tissue in response to estrogens treatment.

abstract：:Nel-like molecule-1 (NELL-1) is a novel highly specific growth factor that can induce osteoblast differentiation and bone formation as well as odontoblast differentiation. Recent studies have suggested that NELL-1 can synergistically increase bone formation and regeneration with bone morphogenetic protein 2 (BMP2) and...

journal_title：Journal of molecular histology

authors： Wu J,Wang Q,Han Q,Zhu H,Li M,Fang Y,Wang X

更新日期：2019-06-01 00:00:00

abstract：:During their commitment and differentiation toward the osteoblast lineage, mesenchymal stem cells secrete a unique extracellular matrix (ECM) that contains large quantities of glycosaminoglycans (GAGs). Proteoglycans (PGs) are major structural and functional components of the ECM and are composed of a core protein to ...

journal_title：Journal of molecular histology

authors： Grünert M,Dombrowski C,Sadasivam M,Manton K,Cool SM,Nurcombe V

更新日期：2007-10-01 00:00:00

abstract：:TGF-β1, SNAI1 and MMP-9 are implicated in tumor invasion and metastasis. The purpose of this study was to examine TGF-β1, SNAI1 and MMP-9 expression in papillary thyroid carcinoma (PTC), and to assess association of TGF-β1, SNAI1 and MMP-9 expression with several clinicopathological indicators of PTC. TGF-β1, SNAI1 an...

journal_title：Journal of molecular histology

authors： Wang N,Jiang R,Yang JY,Tang C,Yang L,Xu M,Jiang QF,Liu ZM

更新日期：2014-08-01 00:00:00

abstract：:Stromal cells in the peripheral zone (PZ) of the prostate from older males (PZ-old) could significantly promote Prostate cancer (PCa) growth compared with stromal cells from young males (PZ-young). But the mechanism is still unknown. In the co-culture system with PZ-old cells, Pc3/Du145 cells showed advanced prolifera...

journal_title：Journal of molecular histology

authors： Zou Q,Cui D,Liang S,Xia S,Jing Y,Han B

更新日期：2016-06-01 00:00:00

abstract：:The members of high-temperature requirement (HtrA) family are evolutionarily conserved serine proteases that combine a trypsin-like protease domain with at least one PDZ interaction domain. HtrA2, a special one, is mainly located in mitochondria and required for maintaining homeostasis. Once released into cytoplasm, H...

journal_title：Journal of molecular histology

authors： Sun H,Li L,Zhou F,Zhu L,Ke K,Tan X,Xu W,Rui Y,Zheng H,Zhou Z,Yang H

更新日期：2013-08-01 00:00:00

abstract：:Some members of aquaporin family (AQP) plays crucial functions in salivary synthesis and secretion. These proteins expression has already been reported during salivary gland formation, however no previous studies in human developing glands have been performed. We evaluated AQP1, 3 and 5 expression through the stages o...

journal_title：Journal of molecular histology

authors： de Paula F,Teshima THN,Hsieh R,Souza MM,Coutinho-Camillo CM,Nico MMS,Lourenco SV

更新日期：2017-12-01 00:00:00

abstract：:Computational modelling of whole biological systems from cells to organs is gaining momentum in cell biology and disease studies. This pathway is essential for the derivation of explanatory frameworks that will facilitate the development of a predictive capacity for estimating outcomes or risk associated with particul...

journal_title：Journal of molecular histology

authors： Moore MN,Noble D

更新日期：2004-09-01 00:00:00

abstract：:Previous studies demonstrate significant roles for passive water channels (aquaporins, AQPs) in maintaining water homeostasis in cell membranes of endometrial cells during decidualisation and embryo implantation. However, there is little information regarding the role of AQPs in the human fallopian tube, specifically ...

journal_title：Journal of molecular histology

authors： Ji YF,Chen LY,Xu KH,Yao JF,Shi YF,Shanguan XJ

更新日期：2013-04-01 00:00:00

abstract：:Chronic stress is regarded as a significant factor in the etiology of the many diseases. Numerous methods have been developed through which the effect of chronic stress is examined. The aim of this study is to demonstrate the new experimental model for analysis of immuno-suppression induced by chronic restraint stress...

journal_title：Journal of molecular histology

authors： Smieško G,Banović P,Gusman V,Simin V,Cimpean AM,Lalošević D

更新日期：2020-08-01 00:00:00

abstract：:Soluble epoxide hydrolase (sEH) is a bifunctional enzyme with a C-terminal epoxide hydrolase activity and an N-terminal phosphatase activity. Arachidonic acid epoxides, previously suggested to be involved in apoptosis, oncogenesis and cell proliferation, are generated by cytochrome P450 epoxygenases and are good subst...

journal_title：Journal of molecular histology

authors： Enayetallah AE,French RA,Grant DF

更新日期：2006-05-01 00:00:00

abstract：:Within the reproductive system, oestrogenic stimulation of uterine and pituitary tissue typically causes a proliferative response accompanied by an angiogenic induction of new blood vessels from existing ones, thereby providing nutrients and oxygen to the growing tissue. The pro-oestrogenic pesticide methoxychlor (MXC...

journal_title：Journal of molecular histology

authors： Goldman JM,Murr AS,Buckalew AR,Schmid JE,Abbott BD

更新日期：2004-05-01 00:00:00

abstract：:p21-activated Kinase 6 (PAK6) is a serine/threonine kinase belonging to the p21-activated kinase (PAK) family. PAK kinases are well-known regulators of a wide variety of cellular functions, including regulation of cytoskeleton rearrangement, cell survival, apoptosis and the mitogen-activated protein kinase signaling p...

journal_title：Journal of molecular histology

authors： Zhao W,Yang J,Shi W,Wu X,Shao B,Wu Q,Chen J,Ni L

更新日期：2011-06-01 00:00:00

abstract：:MicroRNAs are small noncoding RNAs involved in various biological processes. We characterized the expression of miR-344-3p during mouse embryonic development. At E9.5-E10.5 and E15.5, in situ hybridization detected strong miR-344-3p signal in the central nervous system, including the cerebral cortex, hindbrain, cerebe...

journal_title：Journal of molecular histology

authors： Liu Q,He H,Zeng T,Huang Z,Fan T,Wu Q

更新日期：2014-08-01 00:00:00

abstract：:Spinal cord injury frequently results in permanent loss of neurological function. It includes many complex molecular and biochemical mechanisms. G-protein-coupled receptor kinase 6 (GRK6) is an intracellular kinase that regulates the sensitivity of certain G-protein-coupled receptors. Some studies reported GRK2 and GR...

journal_title：Journal of molecular histology

authors： Sun B,Gao Y,Lou D,Wu X,Wei H,Wen H,Deng X,Zhang F

更新日期：2013-06-01 00:00:00

abstract：:MI-ER1 is a novel transcriptional regulator that plays a critical role in embryonic development and is differentially expressed in breast carcinoma. The MI-ER1 protein sequence is highly conserved among species, with 95% identity between mouse and humans and 72% between Xenopus and mouse. There are two major protein i...

journal_title：Journal of molecular histology

authors： Thorne LB,McCarthy PL,Paterno GD,Gillespie LL

更新日期：2008-02-01 00:00:00

abstract：:Recent studies have shown that chronic endothelial dysfunction can impair multiple aspects of renal physiology and, in turn, contribute to renal fibrosis. Sphingosine 1-phosphate (S1P) has been highlighted as an endothelial barrier-stabilizing mediator. The aim of our study was to investigate the effect of FTY720, an ...

journal_title：Journal of molecular histology

authors： Ni H,Chen J,Pan M,Zhang M,Zhang J,Chen P,Liu B

更新日期：2013-12-01 00:00:00

abstract：:DLBCL is the most common lymphoma subtype occurring in older populations as well as in younger HIV infected patients. The current treatment options for DLBCL are effective for most patients yet the relapse rate is high. While many biomarkers for DLBCL exist, they are not in clinical use due to low sensitivity and spec...

journal_title：Journal of molecular histology

authors： Magangane P,Sookhayi R,Govender D,Naidoo R

更新日期：2016-12-01 00:00:00

abstract：:Aquaporins (AQPs), the rapid transition pores for water molecules, play an important role in maintenance of intracellular water balance. Studies showed that AQPs were also involved in occurrence, development, invasion and metastasis of tumors. In this study, we aimed to explore the distribution and expression differen...

journal_title：Journal of molecular histology

authors： Ma J,Zhou C,Yang J,Ding X,Zhu Y,Chen X

更新日期：2016-04-01 00:00:00

abstract：:Dentin is a major component of teeth that protects dental pulp and maintains tooth health. Bone morphogenetic protein (BMP) signaling is required for the formation of dentin. Mice lacking a BMP type I receptor, activin A receptor type 1 (ACVR1), in the neural crest display a deformed mandible. Acvr1 is known to be exp...

journal_title：Journal of molecular histology

authors： Zhang X,Shi C,Zhao H,Zhou Y,Hu Y,Yan G,Liu C,Li D,Hao X,Mishina Y,Liu Q,Sun H

更新日期：2019-02-01 00:00:00

abstract：:Heparan sulfate proteoglycans (HSPGs) are complex and labile macromolecular moieties on the surfaces of cells that control the activities of a range of extracellular proteins, particularly those driving growth and regeneration. Here, we examine the biosynthesis of heparan sulfate (HS) sugars produced by cultured MC3T3...

journal_title：Journal of molecular histology

authors： Nurcombe V,Goh FJ,Haupt LM,Murali S,Cool SM

更新日期：2007-10-01 00:00:00

abstract：:The aim of this study was to investigate oxidative DNA damage during 4-nitroquinoline 1-oxide (4NQO)-induced rat tongue carcinogenesis. For this purpose, male Wistar rats were distributed into three groups of 10 animals each and treated with 50 ppm 4NQO solution through their drinking water for 4, 12, and 20 weeks. Te...

journal_title：Journal of molecular histology

authors： Miranda SR,Noguti J,Carvalho JG,Oshima CT,Ribeiro DA

更新日期：2011-04-01 00:00:00

abstract：:Osteoprotegerin (OPG) and the receptor activator of nuclear factor (NF)-kB ligand (RANKL) are key regulators of osteoclastogenesis. The present study had the main aim of showing the localization of OPG and RANKL mRNA and protein in serial sections of the rat femurs and tibiae by immunohistochemistry (IHC) and in situ ...

journal_title：Journal of molecular histology

authors： Silvestrini G,Ballanti P,Patacchioli F,Leopizzi M,Gualtieri N,Monnazzi P,Tremante E,Sardella D,Bonucci E

更新日期：2005-02-01 00:00:00

abstract：:Hyperglycemia is associated with impairment of heart function. The current study aimed to investigate the ameliorative effect of polydatin-loaded chitosan nanoparticles (PD-CSNPs), polydatin (PD) and metformin (MET) on diabetic cardiomyopathy in rats. Rats divided into six groups; normal-control, diabetic-control, dia...

journal_title：Journal of molecular histology

authors： Mostafa F,Abdel-Moneim A,Abdul-Hamid M,Galaly SR,Mohamed HM

更新日期：2021-01-03 00:00:00

abstract：:S100A8 and S100A9 are calcium-binding proteins expressed in myeloid cells and are markers of numerous inflammatory diseases in humans. S100A9 has been associated with dystrophic calcification in human atherosclerosis. Here we demonstrate S100A8 and S100A9 expression in murine and human bone and cartilage cells. Only S...

journal_title：Journal of molecular histology

authors： Zreiqat H,Howlett CR,Gronthos S,Hume D,Geczy CL

更新日期：2007-10-01 00:00:00

abstract：:Vesicular monoamine transporter 2 (VMAT2) is expressed in pancreatic beta cells and has recently been proposed as a target for measurement of beta cell mass in vivo. We questioned, (1) What proportion of beta cells express VMAT2? (2) Is VMAT2 expressed by other pancreatic endocrine or non-endocrine cells? (3) Is the r...

journal_title：Journal of molecular histology

authors： Saisho Y,Harris PE,Butler AE,Galasso R,Gurlo T,Rizza RA,Butler PC

更新日期：2008-10-01 00:00:00

abstract：:In order to study the presence of sulphated glycoconjugates in the first mineralised layer juxtaposed to the root dentine (the hyaline layer), we have examined the early stages of molar root development by ultrastructural cytochemistry using Cuprolinic Blue combined with enzymatic pretreatment. Upper molars from 10 to...

journal_title：Journal of molecular histology

authors： Tomazela-Herndl SA,Arana-Chavez VE

更新日期：2004-01-01 00:00:00

abstract：:Quercetin (3,5,7,3',4'-pentahydroxyflavone) is one of the most abundant natural flavonoids. It is present in various common vegetables and fruits. In this report, we examined the effect of quercetin on melanogenesis using a three-dimensional reconstituted human epidermal culture model, MelanoDerm, which is a new comme...

journal_title：Journal of molecular histology

authors： Takeyama R,Takekoshi S,Nagata H,Osamura RY,Kawana S

更新日期：2004-02-01 00:00:00

abstract：:The neurovascular structures in the cranial dura mater have been studied with various histological techniques in the past years. In order to obtain a proper approach to reveal the detailed structures, different labeling methods for the cranial vessels and nerve fibers were tested in this study. Firstly, the labeling c...

journal_title：Journal of molecular histology

authors： Wang J,Xu D,Cui J,Wang S,She C,Wang H,Wu S,Zhang J,Zhu B,Bai W

更新日期：2020-10-01 00:00:00

abstract：:The first cell lineage differentiation occurs during the development of mouse 8-cell embryo to blastocyst. Akt is a potent kinase whose role during blastocyst formation has not been elucidated. In the present study, immunofluorescence results showed that the Akt protein was specifically localized to the outer cells of...

journal_title：Journal of molecular histology

authors： Xu S,Pang L,Liu Y,Lian X,Mo K,Lv R,Zhu H,Lv C,Lin J,Sun J,Xu L,Wang S

更新日期：2019-08-01 00:00:00

abstract：:Low muscle strength is observed during the peri-and postmenopausal periods, when the secretion of ovarian hormones is drastically reduced. It is also a predictive of adverse health events as well as incident mobility limitation and disability. The objective of the present study is to study the biochemical and the hist...

journal_title：Journal of molecular histology

authors： Moustafa AM,Boshra V

更新日期：2011-06-01 00:00:00