Neural-specific expression of miR-344-3p during mouse embryonic development.

abstract：:Spinal cord injury frequently results in permanent loss of neurological function. It includes many complex molecular and biochemical mechanisms. G-protein-coupled receptor kinase 6 (GRK6) is an intracellular kinase that regulates the sensitivity of certain G-protein-coupled receptors. Some studies reported GRK2 and GR...

journal_title：Journal of molecular histology

authors： Sun B,Gao Y,Lou D,Wu X,Wei H,Wen H,Deng X,Zhang F

更新日期：2013-06-01 00:00:00

abstract：:Nel-like molecule-1 (NELL-1) is a novel highly specific growth factor that can induce osteoblast differentiation and bone formation as well as odontoblast differentiation. Recent studies have suggested that NELL-1 can synergistically increase bone formation and regeneration with bone morphogenetic protein 2 (BMP2) and...

journal_title：Journal of molecular histology

authors： Wu J,Wang Q,Han Q,Zhu H,Li M,Fang Y,Wang X

更新日期：2019-06-01 00:00:00

abstract：:Multidrug resistance-associated protein 1 (MRP1) belongs to ATP-binding cassette transporters family. The overexpression of MRP1 is predominantly related with the failure of chemo-radiotherapy in various tumors. However, its possible role in hypertrophic scar (HS) is hardly investigated. Here we showed that the mRNA l...

journal_title：Journal of molecular histology

authors： Li Y,Yang L,Zheng Z,Shi J,Wu X,Guan H,Jia Y,Tao K,Wang H,Han S,Gao J,Zhao B,Su L,Hu D

更新日期：2015-10-01 00:00:00

abstract：AIM:To compare the expression of p57 as indirect marker of genomic imprinting of CDKN1C in a series of infantile hemangiomas (IH) of patients with and without Beckwith-Wiedemann syndrome. MATERIALS AND METHODS:Cases of mammary, salivary gland, liver (one each), and placental (2 cases) capillary hemangiomas all with hi...

journal_title：Journal of molecular histology

authors： Drut R,Drut RM

更新日期：2005-03-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is an important angiogenic factor in the pituitary gland. The objective of this study was to unveil the VEGF subcellular localisation in different pituitary cell types and to evaluate changes in its expression at different time intervals after oestrogen stimulation. A relevant...

journal_title：Journal of molecular histology

authors： Mukdsi JH,De Paul AL,Gutiérrez S,Roth FD,Aoki A,Torres AI

更新日期：2005-10-01 00:00:00

abstract：:Previous findings have shown that P2X-purinoceptor-mediated signaling pathways regulate the release of ACh in the retina. We previously reported the existence of immunoreactivity for P2X1-, P2X2-, P2X4-, and P2X7-purinoceptors in mouse retina and speculated that P2X2 and P2X7-purinoceptors may modulate the activity of...

journal_title：Journal of molecular histology

authors： Shigematsu Y,Shimoda Y,Kaneda M

更新日期：2007-08-01 00:00:00

abstract：:Gekko japonicus undergoes dramatic changes in the caudal spinal cord after tail amputation. The amputation induces cell proliferation in the caudal ependymal tube. We performed hematoxylin and eosin staining at different time points in the regeneration process to investigate the morphological characterization of the r...

journal_title：Journal of molecular histology

authors： Zhou Y,Xu Q,Li D,Zhao L,Wang Y,Liu M,Gu X,Liu Y

更新日期：2013-06-01 00:00:00

abstract：:Adipose-derived mesenchymal stem cell (ADSC) with a high capacity of chondrogenic differentiation was a promising candidate for cartilage defect treatment. This study's objective is to study the roles of integrin β1 (ITGB1) in regulating ADSC chondrogenic differentiations as well as the underlying mechanisms. The iden...

journal_title：Journal of molecular histology

authors： Luo S,Shi Q,Li W,Wu W,Zha Z

更新日期：2020-12-01 00:00:00

abstract：:E3 ubiquitin ligases regulate a variety of biological processes through the ubiquitin-proteasome system, together with ubiquitin activating enzyme E1 and ubiquitin-conjugating enzyme E2. Previous studies have demonstrated that zinc and ring finger 3 (ZNRF3), which belongs to the E3 ubiquitin ligases family is involved...

journal_title：Journal of molecular histology

authors： Zhou Y,Lan J,Wang W,Shi Q,Lan Y,Cheng Z,Guan H

更新日期：2013-10-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a major health problem in reproductive-aged women worldwide, but the precise pathogenesis of PCOS remains unclear. Our previous study revealed that hypoxia-inducible factor (HIF)-1a mediated endothelin (ET)-2 signaling plays an important role in ovulation in rats. Therefore, the pre...

journal_title：Journal of molecular histology

authors： Wang F,Zhang Z,Wang Z,Xiao K,Wang Q,Su J,Wang Z

更新日期：2015-04-01 00:00:00

abstract：:Wnt signaling plays important roles in skeletal development. However, the activation and function of canonical Wnt signaling in joint development remains unclear. We analyzed the lineage identity and developmental changes of the Wnt-responsive cells during synovial joint formation as well as adulthood in the Wnt signa...

journal_title：Journal of molecular histology

authors： Yamagami T,Molotkov A,Zhou CJ

更新日期：2009-08-01 00:00:00

abstract：:The natriuretic peptide (NP) system comprises of three ligands, the Atrial Natriuretic Peptide (ANP), Brain Natriuretic peptide (BNP) and C-type Natriuretic peptide (CNP), and three natriuretic peptide receptors, NPRA, NPRB and NPRC. Here we present a comprehensive study of the natriuretic peptide system in healthy mu...

journal_title：Journal of molecular histology

authors： Ahmed A,Gulino A,Amayo S,Arancio W,Florena AM,Belmonte B,Jurjus A,Leone A,Miletich I

更新日期：2020-02-01 00:00:00

abstract：:Recent studies have shown that chronic endothelial dysfunction can impair multiple aspects of renal physiology and, in turn, contribute to renal fibrosis. Sphingosine 1-phosphate (S1P) has been highlighted as an endothelial barrier-stabilizing mediator. The aim of our study was to investigate the effect of FTY720, an ...

journal_title：Journal of molecular histology

authors： Ni H,Chen J,Pan M,Zhang M,Zhang J,Chen P,Liu B

更新日期：2013-12-01 00:00:00

abstract：:During human pregnancy the placenta produces a variety of proteins like steroid hormones and their receptors that are responsible for the establishment and ongoing of the feto-placental unit. Inhibins are dimeric glycoproteins, composed of an alpha-subunit and one of two possible beta-subunits (beta (A) or beta (B)). ...

journal_title：Journal of molecular histology

authors： Mylonas I,Schiessl B,Jeschke U,Vogl J,Makrigiannakis A,Kuhn C,Kunze S,Schulze S,Kainer F,Friese K

更新日期：2006-01-01 00:00:00

abstract：:The distribution of molecular components of interendothelial tight junctions (TJs) was studied in rat blood-brain barrier (BBB) microvessels, using immunogold cytochemistry applied to electron microscopy. Samples of rat brains, both normal (unaffected) and osmotically-affected (1, 5, and 30 min after intracarotid infu...

journal_title：Journal of molecular histology

authors： Dobrogowska DH,Vorbrodt AW

更新日期：2004-06-01 00:00:00

abstract：:Aquaporins (AQPs), the rapid transition pores for water molecules, play an important role in maintenance of intracellular water balance. Studies showed that AQPs were also involved in occurrence, development, invasion and metastasis of tumors. In this study, we aimed to explore the distribution and expression differen...

journal_title：Journal of molecular histology

authors： Ma J,Zhou C,Yang J,Ding X,Zhu Y,Chen X

更新日期：2016-04-01 00:00:00

abstract：:The aim of this study was to ascertain whether, like many cell types in cartilaginous tissues if type XI collagen was a pericellular component of annulus fibrosus (AF) cells and chondrocytes. Fine fibrillar networks were visualised which were perlecan, HS (MAb 10E4) and type XI collagen positive. Heparitinase-III pre-...

journal_title：Journal of molecular histology

authors： Smith SM,Melrose J

更新日期：2019-06-01 00:00:00

abstract：:Zinc is a vital co-factor for insulin metabolism in the pancreatic β-cell, involved in synthesis, maturation, and crystallization. Two families of zinc transporters, namely SLC30A (ZNT) and SLC39A (ZIP) are involved in maintaining cellular zinc homeostasis in mammalian cells. Single nuclear polymorphisms or mutations ...

journal_title：Journal of molecular histology

authors： Cai Y,Kirschke CP,Huang L

更新日期：2018-04-01 00:00:00

abstract：:Odontogenic keratocysts (OKCs) are jaw cystic lesions which are characterized by local invasion and high recurrence rate. The majority of OKCs are exposed to microorganisms and occur along with focal inflammatory infiltrates. Cyst fluids are biological fluids that contain a large content of cytokines and immune globul...

journal_title：Journal of molecular histology

authors： Man QW,Zhong WQ,Zhao YF,Liu B,Zhao Y

更新日期：2019-08-01 00:00:00

abstract：:Epidermal adult stem cells (EpiASCs) have the potential for unlimited proliferation and differentiation, however, the ability of these stem cells to activate corneal genetic programs in response to corneal stroma stimulation needs to be further validated. Herein, a feasible strategy was developed to reconstruct the da...

journal_title：Journal of molecular histology

authors： Zhang P,Ma XY,Huang DT,Yang XY

更新日期：2020-06-01 00:00:00

abstract：:Cyclin G1 plays an essential role in the development of human carcinoma. Here, we characterized the clinical significance of Cyclin G1 and investigated its role in cellular proliferation and apoptosis of epithelial ovarian cancer (EOC). Western blot was used to evaluate the expression of Cyclin G1 in nine fresh EOC ti...

journal_title：Journal of molecular histology

authors： Jiang L,Liu R,Wang Y,Li C,Xi Q,Zhong J,Liu J,Yang S,Wang J,Huang M,Tang C,Fang Z

更新日期：2015-06-01 00:00:00

abstract：:The incidence of chronic renal diseases is increasing worldwide, and there is a great need to identify therapies capable of arresting or reducing disease progression. The current treatment of chronic nephropathies is limited to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, but increasing ...

journal_title：Journal of molecular histology

authors： de Barros EP,Garcia-Pinto AB,Machado PY,dos Santos Pereira MJ,de Carvalho JJ

更新日期：2011-08-01 00:00:00

abstract：:Neutrotrophins are increasingly appreciated as potential modulators of neuronal function in the adult central nervous system (CNS). To describe the neurotrophin environment within the adult CNS, mRNA and protein expression patterns of neurotrophins-3 and -4 and of brain-derived neurotrophin were investigated in adult ...

journal_title：Journal of molecular histology

authors： Riley CP,Cope TC,Buck CR

更新日期：2004-11-01 00:00:00

abstract：:The aim of the present study was to investigate the association between KDM3A expression and the clinicopathological parameters of patients with epithelial ovarian cancer (EOC). KDM3A expression was analyzed using immunohistochemistry in EOC tissue microarray containing 90 paired cases of EOC and matched normal contro...

journal_title：Journal of molecular histology

authors：

更新日期：2016-04-01 00:00:00

abstract：:Previous studies have shown aberrant expression of ubiquitin-specific protease 14 (USP14) in multiple malignancies, suggesting an important role of USP14 in tumorigenesis. However, the functional role of USP14 in pancreatic ductal adenocarcinoma (PDAC) has never been elucidated. In this study, we found that USP14 was ...

journal_title：Journal of molecular histology

authors： Hang C,Gong C,Fang Y,Chen L,Zhu J

更新日期：2021-01-04 00:00:00

abstract：:Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a DNA repair enzyme that processes blocked 3' ends of DNA breaks. Functional loss of Tdp1 causes spinocerebellar ataxia with axonal neuropathy type 1 (SCAN1). Based on the prominent cytoplasmic expression of Tdp1 in the neurons presumably affected in SCAN1, we hypothesized tha...

journal_title：Journal of molecular histology

authors： Fam HK,Chowdhury MK,Walton C,Choi K,Boerkoel CF,Hendson G

更新日期：2013-08-01 00:00:00

abstract：:Despite the efficacy of tamoxifen in preventing disease relapse, a large portion of breast cancer patients show intrinsic or acquired resistance to tamoxifen, leading to treatment failure and unfavorable clinical outcome. MYB proto-oncogene like 2 (MYBL2) is a transcription factor implicated in the initiation and prog...

journal_title：Journal of molecular histology

authors： Li X,Zhang X,Wu CC,Li PP,Fu YM,Xie LH,Sun SS,Zhou YY,Zhu BL

更新日期：2021-02-01 00:00:00

abstract：:Selective cyclooxygenase-2 non-steroidal anti-inflammatory drugs are known to inhibit bone repair, especially when long-term administration is required due to chronicle inflammatory diseases. In order to evaluate the action of this drug in bone repair during short-term administration, 48 rats underwent surgical bone d...

journal_title：Journal of molecular histology

authors： Matsumoto MA,De Oliveira A,Ribeiro Junior PD,Nary Filho H,Ribeiro DA

更新日期：2008-08-01 00:00:00

abstract：:During transmyocardial revascularization, cellular destruction of cardiomyocytes occurs as a result of the high-energy laser. However, the features of myocardial cellular destruction are unclear. The present study was undertaken to examine the structural characteristics of cell death in the myocardium following transm...

journal_title：Journal of molecular histology

authors： Cherian SM,Bobryshev YV,Tran D,Sivaraman A,Lord RS,Cherian KM

更新日期：2005-05-01 00:00:00

abstract：:Previous studies demonstrate significant roles for passive water channels (aquaporins, AQPs) in maintaining water homeostasis in cell membranes of endometrial cells during decidualisation and embryo implantation. However, there is little information regarding the role of AQPs in the human fallopian tube, specifically ...

journal_title：Journal of molecular histology

authors： Ji YF,Chen LY,Xu KH,Yao JF,Shi YF,Shanguan XJ

更新日期：2013-04-01 00:00:00