Clinical syndromes and management of intracerebral hemorrhage.

abstract：PURPOSE OF REVIEW:This review summarizes the pathophysiology of calcific aortic valve stenosis (CAVS) and surveys relevant clinical data and basic research that explain how CAVS arises. RECENT FINDINGS:Lipoprotein(a) [Lp(a)], lipoprotein-associated phospholipase A2 (Lp-PLA2), oxidized phospholipids (OxPL), autotaxin, ...

journal_title：Current atherosclerosis reports

authors： de Oliveira Sá MPB,Cavalcanti LRP,Perazzo ÁM,Gomes RAF,Clavel MA,Pibarot P,Biondi-Zoccai G,Zhigalov K,Weymann A,Ruhparwar A,Lima RC

更新日期：2020-01-07 00:00:00

abstract：:Atherosclerotic cardiovascular diseases are the most common causes of death in the United States. Fibrous plaques develop in 77% to 78% of men before age 30. The mean low-density lipoprotein-cholesterol (LDL-C) level in men aged 25 to 30 years is 117 mg/dL. In the Air Force/Texas Coronary Atherosclerosis Prevention St...

journal_title：Current atherosclerosis reports

authors： Whitney E

更新日期：1999-07-01 00:00:00

abstract：:Erectile dysfunction (ED) is a common problem in the United States, with estimates that 30 million men suffer with some degree of ED. Although causes include psychogenic, organic, and mixed forms, in middle-aged and older men one of the most common causes is vascular disease. Endothelial dysfunction, even without defi...

journal_title：Current atherosclerosis reports

authors： Kloner RA,Speakman M

更新日期：2002-09-01 00:00:00

abstract：:Effective prevention of the current annual $400 billion losses from atherosclerosis and cardiovascular disease (CVD) will require preventing primary causes rather than just decreasing signs and symptoms (risk factors) produced by those causes. All CVD risk factors predict a likelihood of CVD, but not all are causes of...

journal_title：Current atherosclerosis reports

authors： Lands B

更新日期：2009-07-01 00:00:00

abstract：:Recently reported clinical trials raise doubts on the effectiveness of nonstatin lipid-lowering therapies in reducing the residual risk of cardiovascular events after statin monotherapy. Addition of -torcetrapib to statin therapy increased overall mortality in coronary patients despite a marked increase in high-densit...

journal_title：Current atherosclerosis reports

authors： Ansell BJ

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:We provide an overview of our current understanding of combination lipid-lowering therapies intended for dyslipidemia treatment and cardiovascular disease prevention. First, we analyze recent statin and non-statin combination therapy guidelines and clinical studies since the publication of 2013 Americ...

journal_title：Current atherosclerosis reports

authors： Russell C,Sheth S,Jacoby D

更新日期：2018-03-07 00:00:00

abstract：:Diabesity is a term often used to indicate the association of type-2 diabetes mellitus (T2DM) with obesity; the prevalence of both conditions is rapidly increasing worldwide and has reached epidemic proportions. Insulin resistance represents the major determinant of T2DM, which becomes manifest once relative β-cell fa...

journal_title：Current atherosclerosis reports

authors： Castagneto M,Mingrone G

更新日期：2012-12-01 00:00:00

abstract：:Few principles in medicine today are as well accepted as the benefits of using statins to reduce cardiovascular risk factors and to prevent cardiovascular disease. The recent withdrawal of a statin (cerivastatin) has lead to a re-examination of all statins, and an attempt to better assess the risk-benefit ratio of thi...

journal_title：Current atherosclerosis reports

authors： Black DM

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The review aims to describe the differences between men and women in those factors that can influence a worse prognosis in women after an acute cardiovascular event. RECENT FINDINGS:Women adequately treated with current evidence-based medications for acute myocardial infarction and for conventional c...

journal_title：Current atherosclerosis reports

authors： Manfrini O,Cenko E,Bugiardini R

更新日期：2020-09-03 00:00:00

abstract：PURPOSE OF REVIEW:Mutations in both nuclear and mitochondrial genes are associated with the development of atherosclerotic lesions in arteries and may provide a partial explanation to the focal nature of lesion distribution in the arterial wall. This review is aimed to discuss the genetic aspects of atherogenesis with ...

journal_title：Current atherosclerosis reports

authors： Orekhov AN,Ivanova EA,Markin AM,Nikiforov NG,Sobenin IA

更新日期：2020-08-09 00:00:00

abstract：:Abdominal aortic aneurysms (AAAs) are a common but asymptomatic disease that has high susceptibility to rupture. Current therapeutic options are limited to surgical procedures because no pharmacological approaches have been proven to decrease either expansion or rupture of human AAAs. The current dearth of effective m...

journal_title：Current atherosclerosis reports

authors： Lu H,Rateri DL,Bruemmer D,Cassis LA,Daugherty A

更新日期：2012-10-01 00:00:00

abstract：:Since the dawn of civilization, carbohydrate has comprised the largest source of energy in the diet for most populations. The source of the carbohydrate has been from plants in the form of complex carbohydrate high in fiber. Only in affluent cultures has sugar contributed so much of the total energy. When carbohydrate...

journal_title：Current atherosclerosis reports

authors： Connor WE,Duell PB,Connor SL

更新日期：2005-11-01 00:00:00

abstract：:Since initial reports of its association with ischemic stroke appeared in 1988, there has been continued controversy regarding the existence and strength of the association between patent foramen ovale (PFO) and ischemic stroke. Many case-control studies have reported an association between incident cryptogenic ischem...

journal_title：Current atherosclerosis reports

authors： Carpenter DA,Ford AL,Lee JM

更新日期：2010-07-01 00:00:00

abstract：:Stroke is a common and disabling condition. Intravenous tissue plasminogen activator (tPA) administered within 3 h of symptom onset is the standard therapy for eligible patients with acute ischemic stroke. Unfortunately, because of the time limitation, very few patients with ischemic stroke actually receive this treat...

journal_title：Current atherosclerosis reports

authors： Elijovich L,Chong JY

更新日期：2010-09-01 00:00:00

abstract：:Stroke is the second leading cause of mortality world-wide and is well suited for prevention because it has a high prevalence, high burden of economic cost, well-defined modifiable risk factors, and effective prevention measures. Atherosclerosis is one of the major mechanisms of ischemic stroke, but the apparent diffe...

journal_title：Current atherosclerosis reports

authors： Bang OY

更新日期：2006-07-01 00:00:00

abstract：:Outcomes from recent lipid-lowering trials have led to an update of the third Report of the National Cholesterol Education Program (NCEP) Adult Treatment Panel's guidelines for treatment of hypercholesterolemia in adults. The updated NCEP guidelines now offer an optional goal of low-density lipoprotein (LDL) cholester...

journal_title：Current atherosclerosis reports

authors： Sabharwal AK,Boord JB

更新日期：2006-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on recent evidence examining the role gut microbiota play in coronary heart disease. It also provides a succinct overview of current and future therapies targeting the gut microbiota for coronary heart disease risk reduction. RECENT FINDINGS:A consensus has been reached that diffe...

journal_title：Current atherosclerosis reports

authors： Liu H,Zhuang J,Tang P,Li J,Xiong X,Deng H

更新日期：2020-10-16 00:00:00

abstract：:Calcification of atherosclerotic lesions was long thought to be an age - related, passive process, but increasingly data has revealed that atherosclerotic calcification is a more active process, involving complex signaling pathways and bone-like genetic programs. Initially, imaging of atherosclerotic calcification was...

journal_title：Current atherosclerosis reports

authors： Bailey G,Meadows J,Morrison AR

更新日期：2016-08-01 00:00:00

abstract：:Eicosanoids, including epoxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and other oxylipins derived from polyunsaturated fatty acids, have emerging roles in endothelial inflammation and subsequent atherosclerosis. Unlike eicosanoids in the prostanoid series, they are known to be esterified in cell lipids such...

journal_title：Current atherosclerosis reports

authors： Shearer GC,Newman JW

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of recreational drugs has increased globally, with the most commonly used recreational drug being cannabis. As of 2019, 10 states and the District of Columbia have legalized cannabis for recreational use, with more states potentially joining this movement. With the increased legalization of ca...

journal_title：Current atherosclerosis reports

authors： Ghosh M,Naderi S

更新日期：2019-04-12 00:00:00

abstract：:Understanding of the pathophysiology of atherosclerosis can provide new strategies for the prevention and treatment of patients with this common disease. Clinical, epidemiologic, and basic molecular science studies have identified oxidative stress as a factor contributing to the development and progression of atherosc...

journal_title：Current atherosclerosis reports

authors： Schulze PC,Lee RT

更新日期：2005-05-01 00:00:00

abstract：:Managing dyslipidemia is an important part of the primary and secondary prevention of coronary heart disease. Low-density lipoprotein cholesterol reduction remains the primary lipid goal. Patients who have experienced an acute coronary syndrome (ACS) are at very high risk of recurrent adverse cardiovascular events. A ...

journal_title：Current atherosclerosis reports

authors： Polsani VR,Virani SS,Nambi V

更新日期：2009-03-01 00:00:00

abstract：:Clinically, aspirin resistance is defined as the failure of aspirin therapy to prevent an acute vascular thrombotic event despite regular intake of appropriate doses. In the laboratory, aspirin resistance encompasses the drug's failure to attain a particular level of platelet inhibition. From a clinical standpoint, th...

journal_title：Current atherosclerosis reports

authors： Blair P,Freedman JE

更新日期：2008-04-01 00:00:00

abstract：:Cancer survivorship should be defined starting not from completion of treatment, but from the time of diagnosis. Assessing and controlling the cancer patient's cardiovascular risk before, during, and after treatment is crucial to improving their overall outcome. There are many cancer therapies, including but not limit...

journal_title：Current atherosclerosis reports

authors： Chen CL

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:We will review the available data on the epidemiology, pathophysiology, diagnosis, and management of microvascular coronary dysfunction (MCD). RECENT FINDINGS:The study of MCD was pioneered by the Women's Ischemia Syndrome Evaluation (WISE) cohort. New techniques in the diagnosis of this condition, u...

journal_title：Current atherosclerosis reports

authors： Naderi S

更新日期：2018-01-30 00:00:00

abstract：:We have developed, tested, and successfully implemented an affordable, evidence-based, comprehensive cardiovascular disease risk-reduction program for use in primary and secondary prevention settings. The program is administered at hospitals, physician practices, cardiac rehabilitation programs, work sites, shopping m...

journal_title：Current atherosclerosis reports

authors： Gordon NF,Salmon RD,Mitchell BS,Faircloth GC,Levinrad LI,Salmon S,Saxon WE,Reid KS

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:We aimed to summarize recent guidelines, position papers, and high-quality clinical research relating the use of nutraceuticals in the management of individuals at high risk of atherosclerotic cardiovascular disease. RECENT FINDINGS:It is essential that individuals at high risk of cardiovascular dise...

journal_title：Current atherosclerosis reports

authors： Penson PE,Banach M

更新日期：2020-09-18 00:00:00

abstract：PURPOSE OF REVIEW:Non-alcoholic fatty liver disease (NAFLD) is frequently associated with obesity and overweight. It has a broad spectrum of clinical and histological presentations, such as steatosis, inflammation (known as non-alcoholic steatohepatitis or NASH), fibrosis, and cirrhosis. There is increasing evidence th...

journal_title：Current atherosclerosis reports

authors： Caravatto PP,Cohen R

更新日期：2017-10-07 00:00:00

abstract：:Pharmacotherapies with agents that inhibit platelet function have proven to be effective in the treatment of acute coronary syndromes, and in the prevention of complications during and after percutaneous coronary intervention. Because of multiple synergetic pathways of platelet activation and their close interplay wit...

journal_title：Current atherosclerosis reports

authors： Kalra K,Franzese CJ,Gesheff MG,Lev EI,Pandya S,Bliden KP,Tantry US,Gurbel PA

更新日期：2013-12-01 00:00:00

abstract：:Despite the recent decline in mortality from coronary heart disease (CHD), this disease remains the leading killer of US adults of all ages. CHD in young adults is not as well characterized as CHD in older individuals because it occurs less frequently, but this disease can have devastating consequences for young patie...

journal_title：Current atherosclerosis reports

authors： Rubin JB,Borden WB

更新日期：2012-04-01 00:00:00