Cannabis and Cardiovascular Disease.

abstract：:Overwhelming evidence now shows that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (ie, statins) are safe and effective in primary and secondary prevention of cardiovascular disease. Atherosclerosis, the primary cause of heart disease, is directly and independently related to hypercholesterolemia and infl...

journal_title：Current atherosclerosis reports

authors： Orr JD

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the important progress in identifying high-risk atherosclerotic plaques, many key elements are elusive. Advanced imaging modalities provide valuable information about the anatomic and functional plaque characteristics and underscore the presence of multiple plaque morphologies. However, how th...

journal_title：Current atherosclerosis reports

authors： Zaromytidou M,Antoniadis AP,Siasos G,Coskun AU,Andreou I,Papafaklis MI,Lucier M,Feldman CL,Stone PH

更新日期：2016-12-01 00:00:00

abstract：:Several studies confirm cognitive impairment and dementia to be increased after stroke in the elderly. Although not necessarily involving memory deficits, the frequency of cognitive impairments may occur in up to 30% of stroke survivors at 3 months. This impairment may be confounded by preexisting cognitive decline or...

journal_title：Current atherosclerosis reports

authors： Kalaria RN,Ballard C

更新日期：2001-07-01 00:00:00

abstract：:While the discovery of microRNAs has exponentially expanded our understanding of the regulatory mechanisms governing gene networks in many biological processes, the study of these tiny RNA powerhouses in cardiovascular disease is in its infancy. To date, there have been over 1200 human microRNAs identified, and they a...

journal_title：Current atherosclerosis reports

authors： Rayner KJ,Moore KJ

更新日期：2012-10-01 00:00:00

abstract：:The liver X receptors (LXRs) are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily. Since their initial identification more than a decade ago, LXRs have been characterized as key transcriptional regulators of lipid and carbohydrate homeostasis. LXRs are activated by the intra...

journal_title：Current atherosclerosis reports

authors： Nomiyama T,Bruemmer D

更新日期：2008-02-01 00:00:00

abstract：:High-density lipoprotein cholesterol (HDL-C) levels are inversely related to risk of atherosclerotic cardiovascular disease (ASCVD). However, the simplistic assumption that HDL-C levels directly and causally impact atherogenesis has been challenged in recent years. The purpose of this article is to review the current ...

journal_title：Current atherosclerosis reports

authors： Brunham LR

更新日期：2016-12-01 00:00:00

abstract：:Few principles in medicine today are as well accepted as the benefits of using statins to reduce cardiovascular risk factors and to prevent cardiovascular disease. The recent withdrawal of a statin (cerivastatin) has lead to a re-examination of all statins, and an attempt to better assess the risk-benefit ratio of thi...

journal_title：Current atherosclerosis reports

authors： Black DM

更新日期：2002-01-01 00:00:00

abstract：:Cancer survivorship should be defined starting not from completion of treatment, but from the time of diagnosis. Assessing and controlling the cancer patient's cardiovascular risk before, during, and after treatment is crucial to improving their overall outcome. There are many cancer therapies, including but not limit...

journal_title：Current atherosclerosis reports

authors： Chen CL

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery disease (CAD) is a major cause of morbidity and mortality globally and poses a threat to both men and women across their lifespans. There is accumulating evidence to support that CAD may present differently in women and men, ranging from the clinical presentation, diagnosis, and manage...

journal_title：Current atherosclerosis reports

authors： Madan N,Gajo E,Sanghani RM,Volgman AS

更新日期：2020-06-23 00:00:00

abstract：:Atherothrombosis remains a major cause of morbidity and mortality in the western world. The underlying processes associated with clinical expression of atherothrombosis include oxidative stress and proteolysis in relation to neovascularisation and intraplaque hemorrhages, leading to immuno-inflammatory response, cell ...

journal_title：Current atherosclerosis reports

authors： Martinez-Pinna R,Barbas C,Blanco-Colio LM,Tunon J,Ramos-Mozo P,Lopez JA,Meilhac O,Michel JB,Egido J,Martin-Ventura JL

更新日期：2010-05-01 00:00:00

abstract：:A substantial body of epidemiologic data has shed light on the potential protective effects of the Mediterranean diet against atherosclerosis in humans. Many believe the reason the Mediterranean diet is atheroprotective is the elevated consumption of olive oil, an oil poor in saturated fatty acids (SFA) and highly enr...

journal_title：Current atherosclerosis reports

authors： Brown JM,Shelness GS,Rudel LL

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Delayed cerebral ischemia (DCI) is common after subarachnoid hemorrhage (SAH) and represents a significant cause of poor functional outcome. DCI was mainly thought to be caused by cerebral vasospasm; however, recent clinical trials have been unable to confirm this hypothesis. Studies in humans and ani...

journal_title：Current atherosclerosis reports

authors： Geraghty JR,Testai FD

更新日期：2017-10-23 00:00:00

abstract：:We have developed, tested, and successfully implemented an affordable, evidence-based, comprehensive cardiovascular disease risk-reduction program for use in primary and secondary prevention settings. The program is administered at hospitals, physician practices, cardiac rehabilitation programs, work sites, shopping m...

journal_title：Current atherosclerosis reports

authors： Gordon NF,Salmon RD,Mitchell BS,Faircloth GC,Levinrad LI,Salmon S,Saxon WE,Reid KS

更新日期：2001-11-01 00:00:00

abstract：:Pharmacotherapies with agents that inhibit platelet function have proven to be effective in the treatment of acute coronary syndromes, and in the prevention of complications during and after percutaneous coronary intervention. Because of multiple synergetic pathways of platelet activation and their close interplay wit...

journal_title：Current atherosclerosis reports

authors： Kalra K,Franzese CJ,Gesheff MG,Lev EI,Pandya S,Bliden KP,Tantry US,Gurbel PA

更新日期：2013-12-01 00:00:00

abstract：:Diabesity is a term often used to indicate the association of type-2 diabetes mellitus (T2DM) with obesity; the prevalence of both conditions is rapidly increasing worldwide and has reached epidemic proportions. Insulin resistance represents the major determinant of T2DM, which becomes manifest once relative β-cell fa...

journal_title：Current atherosclerosis reports

authors： Castagneto M,Mingrone G

更新日期：2012-12-01 00:00:00

abstract：:Preliminary evidence demonstrating that adding 0.5 mg of colchicine per day to statin and antiplatelet therapy reduced the risk of acute coronary events in patients with stable coronary artery disease has raised the hope that it may prove effective for the long-term secondary prevention of cardiovascular disease. The ...

journal_title：Current atherosclerosis reports

authors： Nidorf SM,Eikelboom JW,Thompson PL

更新日期：2014-03-01 00:00:00

abstract：:Inflammation and oxidative processes are key components of atherosclerosis, from fatty streak formation to plaque rupture and thrombosis. Recent basic and clinical studies have identified a number of inflammatory and oxidative processes that appear to play a direct role in atherothrombosis and identify potentially cli...

journal_title：Current atherosclerosis reports

authors： Shishehbor MH,Hazen SL

更新日期：2004-05-01 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are the key transcription factors regulating lipid metabolism and energy homeostasis. PPARalpha and PPARgamma are known therapeutic targets for hypertriglyceridemia and type 2 diabetes, respectively. The physiologic function of the third member, PPARdelta, has been d...

journal_title：Current atherosclerosis reports

authors： Kang K,Hatano B,Lee CH

更新日期：2007-01-01 00:00:00

abstract：:Erectile dysfunction (ED) is a common problem in the United States, with estimates that 30 million men suffer with some degree of ED. Although causes include psychogenic, organic, and mixed forms, in middle-aged and older men one of the most common causes is vascular disease. Endothelial dysfunction, even without defi...

journal_title：Current atherosclerosis reports

authors： Kloner RA,Speakman M

更新日期：2002-09-01 00:00:00

abstract：:Angioplasty and stenting for intracranial atherosclerotic stenosis (ICAS) are a last resort for patients with high-grade intracranial stenosis with multiple ischemic events unresponsive to medical therapy. Medical management, consisting of aggressive risk factor control and dual antiplatelet therapy, is superior to an...

journal_title：Current atherosclerosis reports

authors： Chatterjee AR,Derdeyn CP

更新日期：2015-08-01 00:00:00

abstract：:Transient ischemic attack (TIA) represents one end of the spectrum of focal brain ischemia, the other being completed infarction or ischemic stroke. The evolving technologic advancements in neuroimaging continue to change and sharpen the definition, epidemiology, and management of TIA. As a powerful risk factor for is...

journal_title：Current atherosclerosis reports

authors： Liberato B,Prabhakaran S,Sacco RL

更新日期：2005-07-01 00:00:00

abstract：:Coronary heart disease (CHD), traditionally considered a male disease, causes far more deaths in women than cancer. The prevalence of CHD is lower in women at any age, but with advancing age, this differential decreases. The clinical outcomes including myocardial infarction mortality, all-cause mortality, and reinfarc...

journal_title：Current atherosclerosis reports

authors： Shah T,Palaskas N,Ahmed A

更新日期：2016-05-01 00:00:00

abstract：:A wide range of structurally unrelated antioxidants inhibit atherosclerosis in animal models of hypercholesterolemia, implicating oxidation of low-density lipoprotein (LDL) in the pathogenesis of atherosclerosis. However, most prospective, randomized trials of one proposed antioxidant, vitamin E, have failed to demons...

journal_title：Current atherosclerosis reports

authors： Heinecke JW

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery no-reflow phenomenon is an incidental outcome of percutaneous coronary intervention in patients presenting with acute myocardial infarction. Despite advances in pharmacologic and non-pharmacologic therapies, coronary no-reflow phenomenon occurs more commonly than desired. It often resu...

journal_title：Current atherosclerosis reports

authors： Karimianpour A,Maran A

更新日期：2018-07-05 00:00:00

abstract：PURPOSE OF REVIEW:The purpose is to review evidence on cardiovascular risks and benefits of new treatments for type 2 diabetes mellitus. RECENT FINDINGS:In response to guidance issued by the Food and Drug Administration, thousands of patients have been enrolled in large randomized trials evaluating the cardiovascular ...

journal_title：Current atherosclerosis reports

authors： Flory JH,Ukena JK,Floyd JS

更新日期：2016-12-01 00:00:00

abstract：:The ability for statins to reduce major cardiovascular events and mortality has lead to this drug class being the most commonly prescribed in the world. In particular, the benefit of these drugs in type 2 diabetes (T2D) is well established. In February 2012, the Food and Drug Administration released changes to statin ...

journal_title：Current atherosclerosis reports

authors： Axsom K,Berger JS,Schwartzbard AZ

更新日期：2013-02-01 00:00:00

abstract：:Plant-derived alpha-linolenic acid has been studied in a limited number of investigations. So far, some epidemiologic and a few mechanistic studies suggest a potential of protection from cardiovascular disease, but this potential remains to be proven in intervention studies. In contrast, eicosapentaenoic acid (EPA) an...

journal_title：Current atherosclerosis reports

authors： von Schacky C

更新日期：2003-03-01 00:00:00

abstract：:Atherothrombotic cardiovascular events are a leading cause of morbidity and mortality in patients with type 2 diabetes (T2D). A number of factors beyond hyperglycemia contribute to this increased risk of cardiovascular events in T2D, including elevated blood pressure, dyslipidemia, inflammation, endothelial dysfunctio...

journal_title：Current atherosclerosis reports

authors： Cameron-Vendrig A,Mundil D,Husain M

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Lipoprotein apheresis is a very efficient but time-consuming and expensive method of lowering levels of low-density lipoprotein cholesterol, lipoprotein(a)) and other apoB containing lipoproteins, including triglyceride-rich lipoproteins. First introduced almost 45 years ago, it has long been a therap...

journal_title：Current atherosclerosis reports

authors： Thompson G,Parhofer KG

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we describe the mechanism behind coronary artery calcification formation and detection, as well as its implication in cardiovascular disease (CVD) risk stratification, intervention, and prognosis in asymptomatic individuals. RECENT FINDINGS:Multiple cohort and population studies have ...

journal_title：Current atherosclerosis reports

authors： Nguyen HL,Liu J,Del Castillo M,Shah T

更新日期：2019-11-21 00:00:00