Abstract:
:UCB (umbilical cord blood) as a resource of MSCs (mesenchymal stem cells) is widely accepted, but the quantity and characteristics of UCB-MSCs from different gestational ages have not been well studied. We have quantified the number of MSCs in UCB at different gestational ages using a multi-colour flowcytometer and compared the cell proliferation rates of these UCB-MSCs. Defining MSCs as CD44+/CD105+/CD34-/CD45 population, their numbers declined in the UCB at the gestational age. Proliferation rates were significantly higher in UCB before term than at full term. Non-full term UCB samples may be a better source of MSCs.
journal_name
Cell Biol Intjournal_title
Cell biology internationalauthors
Ma LL,Meng FB,Shi P,Li G,Pang XNdoi
10.1042/CBI20110173subject
Has Abstractpub_date
2012-04-01 00:00:00pages
415-8issue
4eissn
1065-6995issn
1095-8355pii
CBI20110173journal_volume
36pub_type
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