Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease.

abstract：:A clinical, biochemical, and pathological study is recorded of 50 patients in whom a diagnosis of idiopathic steatorrhea had been made and who had ;flat' jejunal biopsies. It is suggested that there is an underlying constitutional defect, not yet clearly defined, and that possibly secondary intestinal infection allows...

journal_title：Gut

authors： COOKE WT,FONE DJ,COX EV,MEYNELL MJ,GADDIE R

更新日期：1963-09-01 00:00:00

abstract：OBJECTIVE:The natural course of chronic hepatitis C varies widely. To improve the profiling of patients at risk of developing advanced liver disease, we assessed the relative contribution of factors for liver fibrosis progression in hepatitis C. DESIGN:We analysed 1461 patients with chronic hepatitis C with an estimat...

journal_title：Gut

authors： Rüeger S,Bochud PY,Dufour JF,Müllhaupt B,Semela D,Heim MH,Moradpour D,Cerny A,Malinverni R,Booth DR,Suppiah V,George J,Argiro L,Halfon P,Bourlière M,Talal AH,Jacobson IM,Patin E,Nalpas B,Poynard T,Pol S,Abel L,

更新日期：2015-10-01 00:00:00

abstract：:Jejunal absorption of sodium and water has been investigated in 10 normal Indians and 11 patients with chronic tropical sprue. Normal saline and solutions containing amino acids and dipeptides were studied. In both groups little absorption of sodium and water from normal saline was seen. Mean water and sodium absorpti...

journal_title：Gut

authors： Hellier MD,Bhat P,Albert J,Baker SJ

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Lynch syndrome is caused by germline mismatch repair (MMR) gene mutations. The PREMM(1,2,6) model predicts the likelihood of a MMR gene mutation based on personal and family cancer history. OBJECTIVE:To compare strategies using PREMM(1,2,6) and tumour testing (microsatellite instability (MSI) and/or immunoh...

journal_title：Gut

authors： Kastrinos F,Steyerberg EW,Balmaña J,Mercado R,Gallinger S,Haile R,Casey G,Hopper JL,LeMarchand L,Lindor NM,Newcomb PA,Thibodeau SN,Syngal S,Colon Cancer Family Registry.

更新日期：2013-02-01 00:00:00

abstract：:Dysphagia in a 79 year old lady was caused by a giant polypoid tumour in mid-oesophagus. Surgery was not appropriate. Shrinkage of the tumour and its eventual detachment were achieved by stopping its blood supply by YAG laser photocoagulation of the tumour stalk. Good, temporary palliation of the dysphagia was achieve...

journal_title：Gut

authors： Richardson D,Wyatt JI,Miloszewski KJ

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection is associated with a marked infiltration of the gastric epithelium by neutrophils, macrophages, lymphocytes, and plasma cells. Despite the presence of phagocytes in close vicinty to H pylori microbes a great number of people are unable to eradicate bacteria. AIMS:To investigate...

journal_title：Gut

authors： Chmiela M,Czkwianianc E,Wadstrom T,Rudnicka W

更新日期：1997-01-01 00:00:00

abstract：:The actions of hydrochloric acid, natural PGE1, PGE2 and a synthetic commercial PGE1 preparation, Enisoprost (Searle) on pepsinogen synthesis and secretion were studied in canine chief cell monolayer cultures. Hydrochloric acid, applied directly to the apical surface of chief cells using culture plate inserts (Millipo...

journal_title：Gut

authors： Defize J,Hunt RH

更新日期：1989-06-01 00:00:00

abstract：:There is no satisfactory biomarker yet available for predicting the likelihood of premalignant changes or carcinoma developing in Barrett's or columnar lined oesophagus. In this study we have evaluated the proliferation of squamous epithelium, columnar epithelium from columnar lined oesophagus and gastric columnar epi...

journal_title：Gut

authors： Iftikhar SY,Steele RJ,Watson S,James PD,Dilks K,Hardcastle JD

更新日期：1992-06-01 00:00:00

abstract：:The value of the bipolar electrocoagulator in the haemostasis of bleeding ulcers is controversial. We have therefore investigated the effect of different coagulation times on vessel weld strength achieved by the bipolar device. Welds were then made in vessels of known diameter using a standard 10F endoscopic haemostat...

journal_title：Gut

authors： Harrison JD,Morris DL

更新日期：1991-02-01 00:00:00

abstract：:The investigation and treatment of 131 patients with 'obscure' gastrointestinal bleeding has been reviewed. One hundred and six patients were assessed electively for recurrent haemorrhage, 25 presented as emergencies. The major presenting feature was melaena (55 patients), anaemia (35), rectal bleeding (34), haemateme...

journal_title：Gut

authors： Thompson JN,Salem RR,Hemingway AP,Rees HC,Hodgson HJ,Wood CB,Allison DJ,Spencer J

更新日期：1987-01-01 00:00:00

abstract：:Seven patients with hypoalbuminaemia and extensive jejunoileal Crohn's disease were treated with an elemental diet for 28 to 56 days. Over this time there was an increase in total plasma proteins from mean of 49.1 to 59.0 g/l and a mean rise in serum albumin from 20.7 to 30.0 g/l (P less than 0.05). In addition, there...

journal_title：Gut

authors： Logan RF,Gillon J,Ferrington C,Ferguson A

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Surveillance colonoscopy is widely recommended in patients with longstanding and extensive ulcerative colitis (UC) in order to detect colorectal neoplasia at an early stage. However, it still remains questionable whether surveillance colonoscopy effectively enables early detection of UC associated neoplasia....

journal_title：Gut

authors： Fujii S,Tominaga K,Kitajima K,Takeda J,Kusaka T,Fujita M,Ichikawa K,Tomita S,Ohkura Y,Ono Y,Imura J,Chiba T,Fujimori T

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Non-steroidal anti-inflammatory drugs (NSAIDs) have been reported to protect against the development of colon cancer. However, the mechanism(s) by which NSAIDs exert their effects is not clear. AIMS:The aim of this study was to examine the effects of NSAIDs on mRNA expression of tumour suppressor adenomatou...

journal_title：Gut

authors： Kishimoto Y,Takata N,Jinnai T,Morisawa T,Shiota G,Kawasaki H,Hasegawa J

更新日期：2000-12-01 00:00:00

abstract：:Neurotensin is a tridecapeptide located mainly in the distal small intestine. The present study was carried out in order to investigate the neurotensin response after proximal small intestinal resection in the rat. After resection, the median plasma concentration of neurotensin like immunoreactivity (NTLI) was unchang...

journal_title：Gut

authors： Olsen PS,Pedersen JH,Poulsen SS,Yamashita Y,Kirkegaard P

更新日期：1987-09-01 00:00:00

abstract：:A 60 year old man developed steatorrhoea, weight loss, mild diabetes mellitus, labile hypertension and limb cramps. Raised plasma concentrations of catecholamines, particularly noradrenaline and a computed tomography-scan showing an adrenal tumour strongly suggested a pheochromocytoma. Adrenoreceptor blockade reversed...

journal_title：Gut

authors： Thesleff P,Benoni C,Mårtensson H,Nilsson A,Sundler F,Akesson B

更新日期：1987-10-01 00:00:00

abstract：:For the first time the endoscopist has more than one option for the management of gastro-oesophageal varices. It is now feasible to select the appropriate therapy on the basis of the clinical setting. Acute injection sclerotherapy remains a quick and simple technique for the control of active bleeding from oesophageal...

journal_title：Gut

authors： Williams SG,Westaby D

更新日期：1995-05-01 00:00:00

abstract：:The use of tripotassium dicitrato bismuthate (TDB) has been suggested recently for cimetidine resistant duodenal ulcers. This study compares the efficacy of TDB with two different cimetidine dosages in the treatment of duodenal ulcer patients who failed to respond to an eight week therapy with H2-blockers. Fifty two p...

journal_title：Gut

authors： Bianchi Porro G,Parente F,Lazzaroni M

更新日期：1987-07-01 00:00:00

abstract：AIM:To assess the feasibility and diagnostic accuracy of endoscopic ultrasound guided fine needle biopsy (EUS-FNAB) in patients with solid pancreatic masses. METHODS:Ninety nine consecutive patients with pancreatic masses were studied. Histological findings obtained by EUS-FNAB were compared with the final diagnosis a...

journal_title：Gut

authors： Voss M,Hammel P,Molas G,Palazzo L,Dancour A,O'Toole D,Terris B,Degott C,Bernades P,Ruszniewski P

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:Osteopontin (OPN) has been found to be valuable in diagnosis and predicting the prognosis of a variety of malignancies. The aims of the present study are to evaluate the usefulness of plasma OPN level for predicting gastric cancer development, invasion and survival. PATIENTS AND METHODS:One hundred and thirt...

journal_title：Gut

authors： Wu CY,Wu MS,Chiang EP,Wu CC,Chen YJ,Chen CJ,Chi NH,Chen GH,Lin JT

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Polycystic liver diseases (PCLDs) are genetic disorders characterised by progressive bile duct dilatation and/or cyst development. Their pathogenesis is a consequence of hyperproliferation, hypersecretion and microRNA alterations in cholangiocytes. Here we evaluate the role of matrix metalloproteases (MMPs) i...

journal_title：Gut

authors： Urribarri AD,Munoz-Garrido P,Perugorria MJ,Erice O,Merino-Azpitarte M,Arbelaiz A,Lozano E,Hijona E,Jiménez-Agüero R,Fernandez-Barrena MG,Jimeno JP,Marzioni M,Marin JJ,Masyuk TV,LaRusso NF,Prieto J,Bujanda L,Banales JM

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Hepatic stellate cells (HSCs) are a major fibrogenic cell type that contributes to collagen accumulation during chronic liver disease. With increasing interest in developing antifibrotic therapies, there is a need for cell lines that preserve the in vivo phenotype of human HSCs to elucidate pathways of human...

journal_title：Gut

authors： Xu L,Hui AY,Albanis E,Arthur MJ,O'Byrne SM,Blaner WS,Mukherjee P,Friedman SL,Eng FJ

更新日期：2005-01-01 00:00:00

abstract：:A manometric method was developed to study the motor activity in the unprepared human colon, and the results in eight healthy subjects were compared with those obtained in the same subjects after bowel cleansing with a non-absorbable solution containing polyethylene glycol 4000 (PEG). A tube assembly (4.5 m long, 12 l...

journal_title：Gut

authors： Lémann M,Flourié B,Picon L,Coffin B,Jian R,Rambaud JC

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND/AIMS:To investigate the prognostic values of putative hepatic stem/progenitor cell (HSC/HPC) biomarkers in patients with hepatocellular carcinoma (HCC). METHODS:Fourteen biomarkers related to HSCs/HPCs or tumour angiogenesis were assessed by qRT-PCR and then validated by tissue microarrays (TMAs) in three i...

journal_title：Gut

authors： Yang XR,Xu Y,Yu B,Zhou J,Qiu SJ,Shi GM,Zhang BH,Wu WZ,Shi YH,Wu B,Yang GH,Ji Y,Fan J

更新日期：2010-07-01 00:00:00

abstract：:Inflammatory mediators from intestinal mast cells may serve as initiators of acute and delayed inflammation. Mast cell histamine release was measured in 19 patients with inflammatory bowel diseases using gut mast cells from enzymatically dispersed endoscopic forceps biopsy specimens of macroscopically inflamed and nor...

journal_title：Gut

authors： Nolte H,Spjeldnaes N,Kruse A,Windelborg B

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Although peroxisome proliferator activated receptor gamma (PPARgamma) agonists have been implicated in differentiation and growth inhibition of cancer cells, the potential therapeutic and chemopreventive effects on gastric cancer are poorly defined. We examined the in vitro and in vivo effects of PP...

journal_title：Gut

authors： Leung WK,Bai AH,Chan VY,Yu J,Chan MW,To KF,Wu JR,Chan KK,Fu YG,Chan FK,Sung JJ

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Serrated polyposis syndrome (SPS) is associated with an increased risk of colorectal cancer (CRC). International guidelines recommend surveillance intervals of 1-2 years. However, yearly surveillance likely leads to overtreatment for many. We prospectively assessed a surveillance protocol aiming to ...

journal_title：Gut

authors： Bleijenberg AG,IJspeert JE,van Herwaarden YJ,Carballal S,Pellisé M,Jung G,Bisseling TM,Nagtegaal ID,van Leerdam ME,van Lelyveld N,Bessa X,Rodríguez-Moranta F,Bastiaansen B,de Klaver W,Rivero L,Spaander MC,Koornstra JJ,B

更新日期：2020-01-01 00:00:00

abstract：:Circulating immune complexes were determined in 59 consecutive patients with Crohn's disease and 100 blood donors by a double method based on the inhibition of the agglutinating activity of CIq and/or rheumatoid factor on the IgG-coated polystyrene particles. In patients, the incidence of positive immune complexes was...

journal_title：Gut

authors： Fiasse R,Lurhuma AZ,Cambiaso CL,Masson PL,Dive C

更新日期：1978-07-01 00:00:00

abstract：OBJECTIVE:Caffeine reduces toxic Ca2+ signals in pancreatic acinar cells via inhibition of inositol 1,4,5-trisphosphate receptor (IP3R)-mediated signalling, but effects of other xanthines have not been evaluated, nor effects of xanthines on experimental acute pancreatitis (AP). We have determined effects of caffeine an...

journal_title：Gut

authors： Huang W,Cane MC,Mukherjee R,Szatmary P,Zhang X,Elliott V,Ouyang Y,Chvanov M,Latawiec D,Wen L,Booth DM,Haynes AC,Petersen OH,Tepikin AV,Criddle DN,Sutton R

更新日期：2017-02-01 00:00:00

abstract：:Three cases of apparent primary villous atrophy of the terminal ileum in women with chronic diarrhoea are reported. Eight cases have previously been reported in the literature. Clinical characteristics are the presence of severe chronic secretory diarrhoea with episodes of hypokalaemia combined with signs of ileal mal...

journal_title：Gut

authors： Marteau P,Lavergne-Slove A,Lemann M,Bouhnik Y,Bertheau P,Becheur H,Galian A,Rambaud JC

更新日期：1997-10-01 00:00:00

abstract：:An improved technique for the detection of alpha-gliadin sensitised mononuclear cells in the peripheral blood of untreated coeliac patients is described. This method is a modification of the direct LMIF assay, and involves exposure of lymphocytes to alpha-gliadin and the assay of the resultant lymphokine produced usin...

journal_title：Gut

authors： O'Farrelly C,Feighery C,Greally JF,Weir DG

更新日期：1982-01-01 00:00:00