Tripotassium dicitrato bismuthate (TDB) versus two different dosages of cimetidine in the treatment of resistant duodenal ulcers.

abstract：BACKGROUND:In some infants with liver disease, 3-oxo-delta 4 bile acids are the major bile acids in urine, a phenomenon attributed to reduced activity of the delta 4-3-oxosteroid 5 beta-reductase required for synthesis of chenodeoxycholic acid and cholic acid. These patients form a heterogeneous group. Many have a know...

journal_title：Gut

authors： Clayton PT,Mills KA,Johnson AW,Barabino A,Marazzi MG

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:Colorectal cancer (CRC) leads to significant morbidity/mortality worldwide. Defining critical research gaps (RG), their prioritisation and resolution, could improve patient outcomes. DESIGN:RG analysis was conducted by a multidisciplinary panel of patients, clinicians and researchers (n=71). Eight working gr...

journal_title：Gut

authors： Lawler M,Alsina D,Adams RA,Anderson AS,Brown G,Fearnhead NS,Fenwick SW,Halloran SP,Hochhauser D,Hull MA,Koelzer VH,McNair AGK,Monahan KJ,Näthke I,Norton C,Novelli MR,Steele RJC,Thomas AL,Wilde LM,Wilson RH,Tomlins

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:Serous cystic neoplasm (SCN) is a cystic neoplasm of the pancreas whose natural history is poorly known. The purpose of the study was to attempt to describe the natural history of SCN, including the specific mortality. DESIGN:Retrospective multinational study including SCN diagnosed between 1990 and 2014. ...

journal_title：Gut

authors： Jais B,Rebours V,Malleo G,Salvia R,Fontana M,Maggino L,Bassi C,Manfredi R,Moran R,Lennon AM,Zaheer A,Wolfgang C,Hruban R,Marchegiani G,Fernández Del Castillo C,Brugge W,Ha Y,Kim MH,Oh D,Hirai I,Kimura W,Jang JY

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Substance P (SP) is a pro-inflammatory neuropeptide in colitis, whereas sympathetic neurotransmitters are anti-inflammatory at high concentrations. AIM AND METHODS:In all layers of the colon, nerve fibre densities of SP(+) and sympathetic nerve fibres were investigated (22 Crohn's disease, six diverticuliti...

journal_title：Gut

authors： Straub RH,Grum F,Strauch U,Capellino S,Bataille F,Bleich A,Falk W,Schölmerich J,Obermeier F

更新日期：2008-07-01 00:00:00

abstract：:Five patients in whom small-intestinal bypass was performed for severe obesity had a second operation 11-19 months later because of insufficient weight loss. Mucosal enzyme activities and histological appearance were investigated in biopsies from different parts of the functioning and excluded small intestine. These w...

journal_title：Gut

authors： Asp NG,Gudmand-Høyer E,Andersen B,Berg NO

更新日期：1979-07-01 00:00:00

abstract：:An estimated 7.5 million individuals in England and Wales are actively infected with Helicobacter pylori and hence knowledge of local resistance rates is of growing importance. Also, information on strain resistance following treatment failure is crucial in selecting an appropriate regimen as the development of bacter...

journal_title：Gut

authors： Owen RJ

更新日期：2002-03-01 00:00:00

abstract：:With oral and intravenous doses of metoclopramide there was no constant effect on the gastric emptying of test meals of glucose or sodium citrate, nor was secretion of acid by the stomach in response to test meals of glucose or sodium citrate affected. Apomorphine, in subnauseous doses (0.25 mg intravenously) slowed t...

journal_title：Gut

authors： Ramsbottom N,Hunt JN

更新日期：1970-12-01 00:00:00

abstract：:Early carcinoma of the gastric remnant was diagnosed in 19 patients between January 1976 and January 1986. In all patients early cancer was suspected at endoscopy and confirmed by biopsy and histology. The main reason for endoscopic examination was diffuse epigastric pain suggestive of stump gastritis. The surgical pr...

journal_title：Gut

authors： Pointner R,Schwab G,Königsrainer A,Bodner E,Schmid KW

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:Metabolic reprogramming of tumour cells that allows for adaptation to their local environment is a hallmark of cancer. Interestingly, obesity-driven and non-alcoholic steatohepatitis (NASH)-driven hepatocellular carcinoma (HCC) mouse models commonly exhibit strong steatosis in tumour cells as seen in human st...

journal_title：Gut

authors： Fujiwara N,Nakagawa H,Enooku K,Kudo Y,Hayata Y,Nakatsuka T,Tanaka Y,Tateishi R,Hikiba Y,Misumi K,Tanaka M,Hayashi A,Shibahara J,Fukayama M,Arita J,Hasegawa K,Hirschfield H,Hoshida Y,Hirata Y,Otsuka M,Tateishi K,

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND/AIMS:Transjugular intrahepatic portosystemic stent shunt (TIPSS) is effective in the prevention of variceal rebleeding but requires invasive portographic follow up. This randomised controlled trial aims to test the hypothesis that combining variceal band ligation (VBL) with TIPSS can obviate the need for lon...

journal_title：Gut

authors： Tripathi D,Lui HF,Helmy A,Dabos K,Forrest E,Stanley AJ,Jalan R,Redhead DN,Hayes PC

更新日期：2004-03-01 00:00:00

abstract：:Helicobacter pylori possesses unusually high urease activity that lowers the urea concentration and raises the ammonium concentration of the gastric juice in infected people. The value of measuring urea and ammonium concentrations in gastric juice obtained during upper gastrointestinal endoscopy as a means of diagnosi...

journal_title：Gut

authors： Neithercut WD,Milne A,Chittajallu RS,el Nujumi AM,McColl KE

更新日期：1991-09-01 00:00:00

abstract：:In an endoscopic study of 90 consecutive patients with more than one peptic ulcer, the ulcers in an individual were profoundly spatially clustered. Clustering of ulcer locations was shown using a non-parametric test of clustering (Kruskal-Wallis statistic with 89 degrees of freedom = 151.31, probability of observing t...

journal_title：Gut

authors： Cappell MS

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:The major potential site of acid nitrosation is the proximal stomach, an anatomical site prone to a rising incidence of metaplasia and adenocarcinoma. Nitrite, a pre-carcinogen present in saliva, can be converted to nitrosating species and N-nitroso compounds by acidification at low gastric pH in the presenc...

journal_title：Gut

authors： Combet E,Paterson S,Iijima K,Winter J,Mullen W,Crozier A,Preston T,McColl KE

更新日期：2007-12-01 00:00:00

abstract：:Duodenal function was studied in 11 healthy volunteers after intragastric instillation of a mixed semi-elemental meal. The duodenum accepted chyme of varying pH, osmolality, and nutrient concentration; and, as a result of biliary, pancreatic, and enteric secretion as well as absorption, it delivered chyme with nearly ...

journal_title：Gut

authors： Miller LJ,Malagelada JR,Go VL

更新日期：1978-08-01 00:00:00

abstract：:There are sex differences in large bowel cancer rates and a variety of other gastrointestinal disorders possibly because of differences in gut biology. To determine whether men and women have different gastrointestinal responses when consuming identical intakes of dietary fibre, 16 women and 18 men consumed liquid for...

journal_title：Gut

authors： Lampe JW,Fredstrom SB,Slavin JL,Potter JD

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:Liver fibrosis and cirrhosis resulting from chronic liver injury represent a major healthcare burden worldwide. Growth differentiation factor (GDF) 11 has been recently investigated for its role in rejuvenation of ageing organs, but its role in chronic liver diseases has remained unknown. Here, we investigate...

journal_title：Gut

authors： Dai Z,Song G,Balakrishnan A,Yang T,Yuan Q,Möbus S,Weiss AC,Bentler M,Zhu J,Jiang X,Shen X,Bantel H,Jaeckel E,Kispert A,Vogel A,Saborowski A,Büning H,Manns M,Cantz T,Ott M,Sharma AD

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Caroli's disease is a rare congenital disorder characterised by cystic dilatation of the intrahepatic bile ducts and an increased risk of cholangiocellular carcinoma. The cause is unknown, but occasional familial clustering suggests that some cases are inherited, in particular when occurring in association w...

journal_title：Gut

authors： Parada LA,Hallén M,Hägerstrand I,Tranberg KG,Johansson B

更新日期：1999-11-01 00:00:00

abstract：:The faecal blood loss of six alcoholic subjects with normal gastric mucosa, six with superficial gastritis, and six with atrophic gastritis was studied before and during ingestion of 40% v/v ethanol using (51)Cr-tagged red blood cells. No significant change in faecal blood loss was observed in the normal mucosa and su...

journal_title：Gut

authors： Dinoso VP Jr,Meshkinpour H,Lorber SH

更新日期：1973-04-01 00:00:00

abstract：:In a search for past or present infection with herpes viruses, serum antibody titres to herpes simplex type 1 virus, cytomegalovirus, and varicella-zoster virus were measured by complement fixation test in 58 patients with achalasia. Serum was also taken from 40 age and sex matched patients without oesophageal symptom...

journal_title：Gut

authors： Robertson CS,Martin BA,Atkinson M

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND AND AIMS:In acute liver failure (ALF), the brain is exposed to high levels of ammonia. Human studies defining the clinical significance of ammonia in ALF are lacking. This prospective study evaluated the relationship of arterial ammonia levels at admission to complications and survival among patients with AL...

journal_title：Gut

authors： Bhatia V,Singh R,Acharya SK

更新日期：2006-01-01 00:00:00

abstract：:Alkaline phosphatase has been extracted from human pancreas with n-butanol and has been shown to have distinctive isoenzyme characteristics when compared with the enzymes of small intestine and of normal serum. The enzyme has been demonstrated histochemically in a carcinoma of the pancreas and also in an islet cell tu...

journal_title：Gut

authors： Warnes TW,Timperley WR,Hine P,Kay G

更新日期：1972-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Abdominal pain and discomfort are common symptoms in functional disorders and are attributed to visceral hypersensitivity. These symptoms fluctuate over time but the basis for this is unknown. Here we examine the impact of changes in gut flora and gut inflammatory cell activity on visceral sensitivi...

journal_title：Gut

authors： Verdú EF,Bercik P,Verma-Gandhu M,Huang XX,Blennerhassett P,Jackson W,Mao Y,Wang L,Rochat F,Collins SM

更新日期：2006-02-01 00:00:00

abstract：:Earlier studies have reported that faecal pH is more alkaline in patients with colonic cancer, indicating a reduction in colonic carbohydrate fermentation to organic acids. The pH of faeces from 11 pre and 14 postoperative, selected colonic cancer patients without intestinal obstruction, major loss of appetite or weig...

journal_title：Gut

authors： Hove H,Rye Clausen M,Brøbech Mortensen P

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:It has been suggested that slow transit constipation (STC) may be part of a panenteric motor disorder. AIM:To evaluate motility of an upper gastrointestinal organ, the gall bladder, in 16 patients with STC and 20 healthy controls. METHODS:Gall bladder emptying (ultrasonography) was studied in response to n...

journal_title：Gut

authors： Penning C,Gielkens HA,Delemarre JB,Lamers CB,Masclee AA

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Sulfhydryl (SH) compounds are essential in maintaining mucosal integrity in the gastrointestinal tract. A decrease in colonic mucosal SH compounds affects the redox status of the mucosa, resulting in vulnerability to further attacks. Therefore, there is a strong need for in vivo evaluation of SH compounds in...

journal_title：Gut

authors： Togashi H,Oikawa K,Adachi T,Sugahara K,Ito J,Takeda T,Watanabe H,Saito K,Saito T,Fukui T,Takeda H,Ohya H,Kawata S

更新日期：2003-09-01 00:00:00

abstract：:In conditions with increased neutrophil production, the serum total vitamin B(12)-binding capacity (TBBC) is considered to correlate with the blood pool size of neutrophil granulocytes. The serum lysozyme, on the other hand, is a measure of neutrophil (and monocyte) turnover. The mean serum TBBC was significantly rais...

journal_title：Gut

authors： Kane SP,Hoffbrand AV,Neale G

更新日期：1974-12-01 00:00:00

abstract：:The oral administration of loxtidine to mice at doses of 600, 250, and 50 mg/kg/day for 746 days produced carcinoid tumours of the gastric fundus. The fundic mucosa also showed marked atypical hyperplasia with changes in foveolar cells similar to those seen in early incomplete metaplasia. These effects may be related ...

journal_title：Gut

authors： Poynter D,Selway SA,Papworth SA,Riches SR

更新日期：1986-11-01 00:00:00

abstract：:The records of 113 consecutive patients with a suspected gastrointestinal motility disorder referred between January 1988 and July 1991 were retrospectively reviewed. The aims were to identify the prevalence of autonomic dysfunction in those with or without associated neurological disease and to determine the diagnost...

journal_title：Gut

authors： Bharucha AE,Camilleri M,Low PA,Zinsmeister AR

更新日期：1993-03-01 00:00:00

abstract：AIMS:To determine risk factors for peptic ulcer bleeding other than non-steroidal anti-inflammatory drugs (NSAIDs). Methods-Data on possible antecedent risk factors obtained in a large case control study of 1121 patients admitted to hospitals in Glasgow, Newcastle, Nottingham, Oxford, and Portsmouth with bleeding pepti...

journal_title：Gut

authors： Weil J,Langman MJ,Wainwright P,Lawson DH,Rawlins M,Logan RF,Brown TP,Vessey MP,Murphy M,Colin-Jones DG

更新日期：2000-01-01 00:00:00

abstract：:Iron deficiency anaemia is one of the most common disorders in the world. Also, one third of inflammatory bowel disease (IBD) patients suffer from recurrent anaemia. Anaemia has significant impact on the quality of life of affected patients. Chronic fatigue, a frequent IBD symptom itself, is commonly caused by anaemia...

journal_title：Gut

authors： Gasche C,Lomer MC,Cavill I,Weiss G

更新日期：2004-08-01 00:00:00