Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study.

abstract：:The quantification of gastric, pancreatic, biliary, and small bowel functions in man often requires the use of intestinal tubes. In this study, the presence of a transpyloric tube did not alter gastric emptying, acid secretion, or serum gastrin levels in response to an ordinary solid meal. ...

journal_title：Gut

authors： Longstreth GF,Malagelada JR,Go VL

更新日期：1975-10-01 00:00:00

abstract：:Little is known about chronic constipation in infants, toddlers, and preschool children and longterm outcome after treatment. The symptoms of 174 children < or = 4 years of age, who were evaluated for chronic constipation, are reported in this study together with the long-term outcome in 90 of them. Initial symptoms w...

journal_title：Gut

authors： Loening-Baucke V

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Norovirus infection is the most frequent cause of infectious diarrhoea in the western world. This study aimed to characterise functionally and histomorphologically the diseased duodenum in human biopsies. METHODS:Norovirus infection was diagnosed by the Kaplan criteria and confirmed by PCR of stool samples....

journal_title：Gut

authors： Troeger H,Loddenkemper C,Schneider T,Schreier E,Epple HJ,Zeitz M,Fromm M,Schulzke JD

更新日期：2009-08-01 00:00:00

abstract：:Multiple endoscopic specimens were obtained from 58 patients with a columnar lined gesophagus to study the histological and histochemical features of this metaplastic epithelium. Five patients (8.6%) had presented with a primary oesophageal adenocarcinoma. Three different epithelial types, junctional, atrophic fundic ...

journal_title：Gut

authors： Rothery GA,Patterson JE,Stoddard CJ,Day DW

更新日期：1986-09-01 00:00:00

abstract：:For the first time the endoscopist has more than one option for the management of gastro-oesophageal varices. It is now feasible to select the appropriate therapy on the basis of the clinical setting. Acute injection sclerotherapy remains a quick and simple technique for the control of active bleeding from oesophageal...

journal_title：Gut

authors： Williams SG,Westaby D

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Concordance rates in siblings and twins provide strong evidence that genetic susceptibility is important in the pathogenesis of inflammatory bowel disease. The number and identity of susceptibility genes is largely uncertain. Cytokine genes are attractive candidate loci. AIMS:To study allelic frequencies of...

journal_title：Gut

authors： Louis E,Satsangi J,Roussomoustakaki M,Parkes M,Fanning G,Welsh K,Jewell D

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:Osteoporosis and fractures are frequently encountered in patients with Crohn's disease. In order to prevent fractures, treatment with bone protecting drugs appears warranted early in the course of bone disease when bone loss is not yet prominent. We therefore aimed to demonstrate a beneficial effect on bone d...

journal_title：Gut

authors： van Bodegraven AA,Bravenboer N,Witte BI,Dijkstra G,van der Woude CJ,Stokkers PC,Russel MG,Oldenburg B,Pierik M,Roos JC,van Hogezand RA,Dik VK,Oostlander AE,Netelenbos JC,van de Langerijt L,Hommes DW,Lips P,Dutch Initiat

更新日期：2014-09-01 00:00:00

abstract：:Upper gastrointestinal function in response to a mixed nutrient meal was evaluated in hyperthyroid patients, both before and after therapy, and in healthy controls. Gastric secretion, gastric emptying, and pancreatic secretion were all normal and normally integrated postprandially in the hyperthyroid patients. Bile ac...

journal_title：Gut

authors： Miller LJ,Owyang C,Malagelada JR,Gorman CA,Go VL

更新日期：1980-08-01 00:00:00

abstract：:The most reliable method of making a specific aetiological diagnosis of chronic viral hepatitis would be to identify virus specific cytotoxic T lymphocytes responsible for the killing of virus infected hepatocytes in each patient's liver. Unfortunately, this can not be proposed for routine diagnosis and surrogate test...

journal_title：Gut

authors： Bonino F,Colloredo Mels G,Bellati G,Ideo G,Oliveri F,Colombatto P,Brunetto MR

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Recently identified ABCG5/8 transporters are responsible in part for the different absorption rates of campesterol, sitosterol, and cholesterol. These transporters are also expressed in the liver and might regulate biliary sterol secretion. AIMS:This study was therefore conducted to determine the biliary se...

journal_title：Gut

authors： Sudhop T,Sahin Y,Lindenthal B,Hahn C,Lüers C,Berthold HK,von Bergmann K

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Population-based studies demonstrating the clinical impact of interferon-free direct-acting antiviral (DAA) therapies are lacking. We examined the impact of the introduction of DAAs on HCV-related decompensated cirrhosis (DC) through analysis of population-based data from Scotland. DESIGN:Through analysis of...

journal_title：Gut

authors： Hutchinson SJ,Valerio H,McDonald SA,Yeung A,Pollock K,Smith S,Barclay S,Dillon JF,Fox R,Bramley P,Fraser A,Kennedy N,Gunson RN,Templeton K,Innes H,McLeod A,Weir A,Hayes PC,Goldberg D

更新日期：2020-12-01 00:00:00

abstract：:A fifth instance of Crohn's disease in identical twins is reported. The evidence for genetic expression of the disease is considered and the possible mechanisms involved are reviewed. ...

journal_title：Gut

authors： Hislop IG,Grant AK

更新日期：1969-12-01 00:00:00

abstract：:The radio-telemetering capsule (radio-pill) has been used to study the return of motility in the small bowel after vagotomy with a drainage procedure, gastric operations not involving vagotomy, and non-gastric operations. Small intestinal movements returned in about 10 hours after vagotomy, about four hours after the ...

journal_title：Gut

authors： ROSS B,WATSON BW,KAY AW

更新日期：1963-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The authors have previously isolated a putative oncogene, eukaryotic initiation factor 5A2 (EIF5A2) from 3q26. In this study, EIF5A2 was characterised for its role in colorectal carcinoma (CRC) aggressiveness and underlying molecular mechanisms. METHODS:The expression dynamics of EIF5A2 were examin...

journal_title：Gut

authors： Zhu W,Cai MY,Tong ZT,Dong SS,Mai SJ,Liao YJ,Bian XW,Lin MC,Kung HF,Zeng YX,Guan XY,Xie D

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:MicroRNAs (miRNAs) have been shown to offer great potential in the diagnosis of cancer. We investigated whether plasma miRNAs could discriminate between patients with and without colorectal cancer (CRC). METHODS:This study was divided into three phases: (1) marker discovery using real-time PCR-based miRNA pr...

journal_title：Gut

authors： Ng EK,Chong WW,Jin H,Lam EK,Shin VY,Yu J,Poon TC,Ng SS,Sung JJ

更新日期：2009-10-01 00:00:00

abstract：:Colonic exfoliated epithelial cells in faecal material provide a source of human DNA which has been analysed for the presence of the tumour marker ras, in order to detect early tumour cells. The stool samples were subjected to a preliminary sample preparation step followed by centrifugation. DNA was extracted from bot...

journal_title：Gut

authors： Smith-Ravin J,England J,Talbot IC,Bodmer W

更新日期：1995-01-01 00:00:00

abstract：:Patients with chronic active hepatitis or alcoholic cirrhosis have serum antibodies to many more serotypes of Escherichia coli than do patients with primary biliary cirrhosis or cryptogenic cirrhosis, or normal controls. They also have antibodies against more serotypes than cirrhotic patients with a portacaval shunt. ...

journal_title：Gut

authors： Simjee AE,Hamilton-Miller JM,Thomas HC,Brumfitt W,Sherlock S

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:Liver fibrosis and cirrhosis resulting from chronic liver injury represent a major healthcare burden worldwide. Growth differentiation factor (GDF) 11 has been recently investigated for its role in rejuvenation of ageing organs, but its role in chronic liver diseases has remained unknown. Here, we investigate...

journal_title：Gut

authors： Dai Z,Song G,Balakrishnan A,Yang T,Yuan Q,Möbus S,Weiss AC,Bentler M,Zhu J,Jiang X,Shen X,Bantel H,Jaeckel E,Kispert A,Vogel A,Saborowski A,Büning H,Manns M,Cantz T,Ott M,Sharma AD

更新日期：2020-06-01 00:00:00

abstract：:Three-day faecal collections were obtained from 87 patients with a variety of gastroenterological diagnoses and 12 control subjects while consuming normal diets. Faecal weight, total fatty acids, and the proportion of hydroxystearic (OHSA) acid were measured. All patients had some easily detectable hydroxystearic acid...

journal_title：Gut

authors： Wiggins HS,Pearson JR,Walker JG,Russell RI,Kellock TD

更新日期：1974-08-01 00:00:00

abstract：:Five patients in whom small-intestinal bypass was performed for severe obesity had a second operation 11-19 months later because of insufficient weight loss. Mucosal enzyme activities and histological appearance were investigated in biopsies from different parts of the functioning and excluded small intestine. These w...

journal_title：Gut

authors： Asp NG,Gudmand-Høyer E,Andersen B,Berg NO

更新日期：1979-07-01 00:00:00

abstract：:Bran, ispaghula (Fybogel), and lactulose were given to three groups of patients with diverticular disease for four weeks. Faecal weights, bile acids, fat and electrolytes, transit time, and colonic motility were estimated before and after treatment. Stool weight increased, notably with Fybogel. Cereal bran had the gre...

journal_title：Gut

authors： Eastwood MA,Smith AN,Brydon WG,Pritchard J

更新日期：1978-12-01 00:00:00

abstract：:The case of a 44-year-old woman is reported. The diagnosis after the appropriate tests and laparotomy was ACTH-secreting 'apudoma' of the gallbladder. This is a rare tumour and this case is believed to be the first reported of an ectopic hormone producing tumour from this side. ...

journal_title：Gut

authors： Spence RW,Burns-Cox CJ

更新日期：1975-06-01 00:00:00

abstract：:Over 90% of patients with inoperable carcinoma of the pancreas are successfully palliated by endoscopic retrograde cholangiopancreatography and stent insertion. Treatment of the residual 10% of patients often entails a laparotomy, which is difficult to justify when median survival of these patients is only 150 days. L...

journal_title：Gut

authors： Rhodes M,Nathanson L,Fielding G

更新日期：1995-05-01 00:00:00

abstract：:Data concerning the effects of morphine on human pancreatic secretion are fragmentary and inconclusive. In the present study, we evaluated the effects of morphine on pure pancreatic secretion in nine subjects with external transduodenal drainage of the main pancreatic duct performed after biliary tract surgery. Intrav...

journal_title：Gut

authors： Gullo L,Priori P,Costa PL,Garcea D,Baldoni F,Mattioli G,Labo G

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVE:Bleeding after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) is a frequent adverse event after ESD. We aimed to develop and externally validate a clinically useful prediction model (BEST-J score: Bleeding after ESD Trend from Japan) for bleeding after ESD for EGC. DESIGN:This retrospe...

journal_title：Gut

authors： Hatta W,Tsuji Y,Yoshio T,Kakushima N,Hoteya S,Doyama H,Nagami Y,Hikichi T,Kobayashi M,Morita Y,Sumiyoshi T,Iguchi M,Tomida H,Inoue T,Koike T,Mikami T,Hasatani K,Nishikawa J,Matsumura T,Nebiki H,Nakamatsu D,Ohnit

更新日期：2020-06-04 00:00:00

abstract：:Management strategies for reflux disease are very different from those for dyspepsia and so differentiating between patients with "true" dyspepsia and those whose primary symptom is heartburn is a key step in their management. This separation has become more clear during the last decade as insights into reflux disease...

journal_title：Gut

authors： Dent J

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Hereditary pancreatitis (HP) is a rare autosomal dominant disorder with variable expression and an overall lifetime penetrance of 80%. We hypothesised that (1) monozygotic twins within similar environments would develop the typical signs of HP at a similar age, and (2) if penetrance were due to modifier gene...

journal_title：Gut

authors： Amann ST,Gates LK,Aston CE,Pandya A,Whitcomb DC

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Interleukin 8 (IL-8) has recently been proposed to have an important role in mediating the development of the systemic sequelae associated with severe acute pancreatitis. AIMS:To define the role of IL-8 in acute pancreatitis by neutralising its effects with a monoclonal anti-IL-8 antibody (WS-4), in a rabbi...

journal_title：Gut

authors： Osman MO,Kristensen JU,Jacobsen NO,Lausten SB,Deleuran B,Deleuran M,Gesser B,Matsushima K,Larsen CG,Jensen SL

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVES:Patients with gallbladder carcinoma (GBC) lack effective treatment methods largely due to the inadequacy of both molecular characterisation and potential therapeutic targets. We previously uncovered a spectrum of genomic alterations and identified recurrent mutations in the ErbB pathway in GBC. Here, we aime...

journal_title：Gut

authors： Li M,Liu F,Zhang F,Zhou W,Jiang X,Yang Y,Qu K,Wang Y,Ma Q,Wang T,Bai L,Wang Z,Song X,Zhu Y,Yuan R,Gao Y,Liu Y,Jin Y,Li H,Xiang S,Ye Y,Zhang Y,Jiang L,Hu Y,Hao Y,Lu W,Chen S,Gu J,Zhou J,Gong W,Z

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:There is a widespread notion that obesity leads to gastro-oesophageal reflux but scientific evidence of an association is limited and inconsistent. AIMS:To estimate the strength of the association between body mass and reflux symptoms, we performed a population based cross sectional interview study. SUBJEC...

journal_title：Gut

authors： Lagergren J,Bergström R,Nyrén O

更新日期：2000-07-01 00:00:00