The gastric response to a transpyloric duodenal tube.


:The quantification of gastric, pancreatic, biliary, and small bowel functions in man often requires the use of intestinal tubes. In this study, the presence of a transpyloric tube did not alter gastric emptying, acid secretion, or serum gastrin levels in response to an ordinary solid meal.






Longstreth GF,Malagelada JR,Go VL





Has Abstract


1975-10-01 00:00:00














  • Intestinal permeability in patients with Crohn's disease and their first degree relatives.

    abstract::It has been reported that intestinal permeability to polyethylene glycol 400 is increased in patients with Crohn's disease and their apparently unaffected first degree relatives. Because of the implications that these findings have for the aetiology of Crohn's disease these studies were repeated. Patients with Crohn's...


    pub_type: 杂志文章


    authors: Teahon K,Smethurst P,Levi AJ,Menzies IS,Bjarnason I

    更新日期:1992-03-01 00:00:00

  • Peptic ulcer and non-steroidal anti-inflammatory agents.

    abstract::Aspirin is generally regarded as a cause of gastric ulcer but the role of non-steroidal anti-inflammatory agents and paracetamol in the aetiology of peptic ulcer is unclear. To investigate this we conducted a case control study of 180 matched pairs of peptic ulcer patients and controls obtained from surgical and derma...


    pub_type: 杂志文章


    authors: Duggan JM,Dobson AJ,Johnson H,Fahey P

    更新日期:1986-08-01 00:00:00

  • Factor VII levels as a guide to prognosis in fulminant hepatic failure.

    abstract::Levels of clotting factors II, V, and VII were measured on admission and then daily in 12 patients with grade IV hepatic coma due to fulminant hepatic failure. Factor VII levels obtained within 36 hours of the development of grade IV coma were not of value in predicting which patients would subsequently recover consci...


    pub_type: 杂志文章


    authors: Gazzard BG,Henderson JM,Williams R

    更新日期:1976-07-01 00:00:00

  • Bone histomorphometry and structure in corticosteroid treated chronic active hepatitis.

    abstract::Transiliac biopsies from 34 female patients with corticosteroid treated chronic active hepatitis have been examined to determine the contributions made by decreased bone formation and increased bone resorption to bone loss associated with this condition and to determine the structural basis of the bone loss. Mean wall...


    pub_type: 杂志文章


    authors: Stellon AJ,Webb A,Compston JE

    更新日期:1988-03-01 00:00:00

  • Natural history of recurrent Crohn's disease at the ileocolonic anastomosis after curative surgery.

    abstract::An endoscopical and histological study was carried out in 114 patients, treated by 'curative' resection of the terminal ileum and part of the colon for Crohn's disease, in order to study the natural history of recurrent Crohn's disease. The recurrence rate of Crohn's disease in patients examined within one year of the...


    pub_type: 杂志文章


    authors: Rutgeerts P,Geboes K,Vantrappen G,Kerremans R,Coenegrachts JL,Coremans G

    更新日期:1984-06-01 00:00:00

  • Blockade of the integrin alphaLbeta2 but not of integrins alpha4 and/or beta7 significantly prolongs intestinal allograft survival in mice.

    abstract:BACKGROUND:Small bowel transplantation remains a difficult therapeutic option endangered by a high rate of rejection and infectious complications. To improve these clinical results, it is mandatory to set up animal models to test alternative immunosuppressive regimens which may lead to immunotolerance. AIMS:To determi...


    pub_type: 杂志文章


    authors: Sarnacki S,Auber F,Crétolle C,Camby C,Cavazzana-Calvo M,Müller W,Wagner N,Brousse N,Révillon Y,Fischer A,Cerf-Bensussan N

    更新日期:2000-07-01 00:00:00

  • DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population.

    abstract:INTRODUCTION:Recent data have suggested that specific haplotypic variants of the DLG5 gene on chromosome 10q23 may be associated with susceptibility to inflammatory bowel disease (IBD) in Germany. Haplotype D, notably characterised by the presence of a G-->A substitution at nucleotide 113, was associated with susceptib...


    pub_type: 杂志文章


    authors: Noble CL,Nimmo ER,Drummond H,Smith L,Arnott ID,Satsangi J

    更新日期:2005-10-01 00:00:00

  • Nippostrongylus brasiliensis infection in the rat: effect of iron and protein deficiency on the anthelmintic efficacy of mebendazole, pyrantel, piperazine, and levamisole.

    abstract::The benzimidazole anthelmintics mebendazole and fenbendazole have been shown to be much less effective against Nippostrongylus brasiliensis infections in the rat on a combined iron and protein deficient diet. In the present experiments it was shown that the anthelmintic efficacy of mebendazole was significantly impair...


    pub_type: 杂志文章


    authors: Duncombe VM,Bolin TD,Davis AE,Fagan MR,Kelly JD

    更新日期:1979-04-01 00:00:00

  • Extracorporeal lithotripsy of pancreatic stones in patients with chronic pancreatitis and pain: a prospective follow up study.

    abstract::Extracorporeal shock wave lithotripsy of pancreatic duct stones (largest stone 12 (SD) 6 mm) was performed in 24 patients with abdominal pain and a dilated duct system (main pancreatic duct 10 (3) mm). The procedure was well tolerated in all but two patients, who had a mild pancreatitic attack immediately after lithot...


    pub_type: 杂志文章


    authors: Sauerbruch T,Holl J,Sackmann M,Paumgartner G

    更新日期:1992-07-01 00:00:00

  • The sequential therapy regimen for Helicobacter pylori eradication: a pooled-data analysis.

    abstract:BACKGROUND:Standard triple therapies are the most used treatment in clinical practice. However, a critical fall in the H pylori eradication rate following these therapies has been observed in the last few years. The sequential regimen is a novel, promising therapeutic approach. OBJECTIVES:To evaluate the available dat...


    pub_type: 杂志文章,meta分析,评审


    authors: Zullo A,De Francesco V,Hassan C,Morini S,Vaira D

    更新日期:2007-10-01 00:00:00

  • Histamine and duodenal ulceration in renal transplant recipients.

    abstract::Six of 25 renal transplant recipients had a duodenal ulcer at endoscopy. Histamine concentration and the activity of histamine methyltransferase, the degrading enzyme of histamine, were measured in gastric mucosal biopsies obtained at endoscopy and compared with patients with duodenal ulcer but not undergoing transpla...


    pub_type: 杂志文章


    authors: Timoney AG,Man WK,Spencer J,Taylor H,Williams G

    更新日期:1989-01-01 00:00:00

  • Global DNA hypomethylation occurs in the early stages of intestinal type gastric carcinoma.

    abstract:BACKGROUND:Global DNA hypomethylation has been found in the premalignant stages of some neoplasms and has been implicated as an important factor for tumour progression. AIMS:The aim of this study was to evaluate whether DNA hypomethylation occurs during the process of gastric carcinogenesis. METHODS:Gastric specimens...


    pub_type: 杂志文章


    authors: Cravo M,Pinto R,Fidalgo P,Chaves P,Glória L,Nobre-Leitão C,Costa Mira F

    更新日期:1996-09-01 00:00:00

  • Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19.

    abstract:OBJECTIVE:Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was detected in faeces of patients with COVID-19, the activity and infectivity of the virus in the GI tract during disease course is largely unknown. We investigated temporal transcriptional activity of SARS-CoV-2 and its association wi...


    pub_type: 杂志文章


    authors: Zuo T,Liu Q,Zhang F,Lui GC,Tso EY,Yeoh YK,Chen Z,Boon SS,Chan FK,Chan PK,Ng SC

    更新日期:2021-02-01 00:00:00

  • Changes in the gastric mucosa of the mouse associated with long lasting unsurmountable histamine H2 blockade.

    abstract::The oral administration of loxtidine to mice at doses of 600, 250, and 50 mg/kg/day for 746 days produced carcinoid tumours of the gastric fundus. The fundic mucosa also showed marked atypical hyperplasia with changes in foveolar cells similar to those seen in early incomplete metaplasia. These effects may be related ...


    pub_type: 杂志文章


    authors: Poynter D,Selway SA,Papworth SA,Riches SR

    更新日期:1986-11-01 00:00:00

  • Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis.

    abstract:OBJECTIVE:The colonic inner mucus layer protects us from pathogens and commensal-induced inflammation, and has been shown to be defective in active UC. The aim of this study was to determine the underlying compositional alterations, their molecular background and potential contribution to UC pathogenesis. DESIGN:In th...


    pub_type: 杂志文章


    authors: van der Post S,Jabbar KS,Birchenough G,Arike L,Akhtar N,Sjovall H,Johansson MEV,Hansson GC

    更新日期:2019-12-01 00:00:00

  • Clinical and laboratory study of postvagotomy diarrhoea.

    abstract::Thirty-two patients with diarrhoea, on average four years following truncal vagotomy and drainage, were studied. A comparison was made with 24 patients without postvagotomy diarrhoea. The incidence of bacterial colonization of the upper small intestine was no different in the two groups, though patients with a gastroe...


    pub_type: 杂志文章


    authors: Browning GG,Buchan KA,Mackay C

    更新日期:1974-08-01 00:00:00

  • Immunological features of lung lavage cells from patients with primary biliary cirrhosis may reflect those seen in pulmonary sarcoidosis.

    abstract::To investigate the basis of subclinical alveolitis in patients with primary biliary cirrhosis, 10 primary biliary cirrhosis patients were studied by bronchoalveolar lavage. Both bronchoalveolar lavage lymphoid and non-lymphoid cell populations were analysed using immunocytological methods to determine their proportion...


    pub_type: 杂志文章


    authors: Spiteri MA,Johnson M,Epstein O,Sherlock S,Clarke SW,Poulter LW

    更新日期:1990-02-01 00:00:00

  • The British Society of Gastroenterology early gastric cancer/dysplasia survey: an interim report.

    abstract::This presentation describes interim findings in a series of 319 patients referred from 41 hospitals on the basis of histopathological findings of 'early gastric cancer', 'dysplasia', or 'worrying mucosal appearances'. Data were recorded using a predefined proforma, and histopathological material circulated amongst a '...


    pub_type: 临床试验,杂志文章,多中心研究


    authors: de Dombal FT,Price AB,Thompson H,Williams GT,Morgan AG,Softley A,Clamp SE,Unwin BJ

    更新日期:1990-01-01 00:00:00

  • Metabolism of 125I-labelled trypsin in man: evidence of recirculation.

    abstract::125I-labelled human trypsin metabolism has been investigated in man. Three subjects received 125I-trypsin and 131I-albumin intravenously. Against a background secretin infusion (1 U/kg/h), trypsin decayed biexponentially from the serum with half-lives of 17.5, 21, and 24 minutes for the rapid disappearance phase and 5...


    pub_type: 杂志文章


    authors: Lake-Bakaar G,Rubio CE,McKavanagh S,Potter BJ,Summerfield JA

    更新日期:1980-07-01 00:00:00

  • Inflammatory bowel disease and risk of small bowel cancer: a binational population-based cohort study from Denmark and Sweden.

    abstract:OBJECTIVE:Crohn's disease (CD) is associated with increased risk of small bowel cancer (SBC), but previous studies have been small. We aimed to examine the risk of incident SBC and death from SBC in patients with inflammatory bowel disease (IBD). DESIGN:In a binational, population-based cohort study from Sweden and De...


    pub_type: 杂志文章


    authors: Axelrad JE,Olén O,Sachs MC,Erichsen R,Pedersen L,Halfvarson J,Askling J,Ekbom A,Sørensen HT,Ludvigsson JF

    更新日期:2021-02-01 00:00:00

  • Principles of applied neurogastroenterology: physiology/motility-sensation.

    abstract::Many of the symptoms characteristic of the functional gastrointestinal disorders (FGID) are consistent with dysfunction of the motor and/or sensory apparatus of the digestive tract. Those aspects of sensorimotor dysfunction most relevant to the FGID include alterations in: gut contractile activity; myoelectrical activ...


    pub_type: 杂志文章,评审


    authors: Kellow JE,Delvaux M,Azpiroz F,Camilleri M,Quigley EM,Thompson DG

    更新日期:1999-09-01 00:00:00

  • Impaired lymphocyte reactivity against tumour cells in patients with Crohn's disease.

    abstract::Evidence is presented which indicates a possible reduction in recognition capacity for tumour cell antigens (EB(2) Burkitt lymphoma cell line) by lymphocytes from some patients with longstanding but inactive Crohn's disease. Three out of seven patients tested also showed diminished or absent lymphocytotoxicity when th...


    pub_type: 杂志文章


    authors: Maclaurin BP,Cooke WT,Ling NR

    更新日期:1972-08-01 00:00:00

  • Elution of cytomegalovirus antibodies from adenocarcinoma of the colon.

    abstract::Eluates were prepared by high salt extraction from normal colonic mucosa and adenocarcinomatous tissue from 28 patients, eight more from unmatched colonic tissue and five from patients with other gastrointestinal disease. Immunoglobulins were detected by ELISA: IgG was present in 24% eluates from normal colon and 21% ...


    pub_type: 杂志文章


    authors: Grail A,Norval M

    更新日期:1985-10-01 00:00:00

  • Effect of dietary nucleotides on small intestinal repair after diarrhoea. Histological and ultrastructural changes.

    abstract::The effects of specific nutrients on intestinal maturation and repair after injury are practically unknown. The purpose of this work was to study the effects of dietary nucleotides on the repair of the intestinal mucosa after chronic diarrhoea induced by a lactose enriched diet in the weanling rat. One group of weanli...


    pub_type: 杂志文章


    authors: Bueno J,Torres M,Almendros A,Carmona R,Nuñez MC,Rios A,Gil A

    更新日期:1994-07-01 00:00:00

  • Liver dysfunction related to hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive therapy.

    abstract:BACKGROUND:There is no information about the frequency of liver dysfunction in patients with inflammatory bowel disease (IBD) treated with immunosuppressants and infected with hepatitis B (HBV) and/or C virus (HCV). AIM:To assess the influence of immunosuppressants on the course of HBV and HCV infection in IBD. METHO...


    pub_type: 杂志文章,多中心研究


    authors: Loras C,Gisbert JP,Mínguez M,Merino O,Bujanda L,Saro C,Domenech E,Barrio J,Andreu M,Ordás I,Vida L,Bastida G,González-Huix F,Piqueras M,Ginard D,Calvet X,Gutiérrez A,Abad A,Torres M,Panés J,Chaparro M,Pascual I

    更新日期:2010-10-01 00:00:00

  • Effects of olsalazine and sulphasalazine on jejunal and ileal water and electrolyte absorption in normal human subjects.

    abstract::The effect of sulphasalazine and olsalazine on jejunal and ileal water and electrolyte absorption was investigated in normal subjects by a steady state intestinal perfusion of a physiological glucose bicarbonate electrolyte solution in the absence and presence of increasing concentrations of each drug. (Olsalazine 0.2...


    pub_type: 杂志文章


    authors: Raimundo AH,Patil DH,Frost PG,Silk DB

    更新日期:1991-03-01 00:00:00

  • Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn's disease: long-term outcomes for 11 928 patients in the UK inflammatory bowel disease bioresource.

    abstract:OBJECTIVE:Thiopurines are widely used as maintenance therapy in inflammatory bowel disease (IBD) but the evidence base for their use is sparse and their role increasingly questioned. Using the largest series reported to date, we assessed the long-term effectiveness of thiopurines in ulcerative colitis (UC) and Crohn's ...


    pub_type: 杂志文章


    authors: Stournaras E,Qian W,Pappas A,Hong YY,Shawky R,UK IBD BioResource Investigators.,Raine T,Parkes M,UK IBD Bioresource Investigators.

    更新日期:2020-10-01 00:00:00

  • Ranitidine, diarrhoea, and lymphocytic colitis.

    abstract::A 69 year old woman developed chronic diarrhoea while being treated with ranitidine. Sigmoidoscopy was performed after six weeks and showed typical histological features of lymphocytic colitis. Ranitidine was withdrawn and the diarrhoea resolved. Eight months later, a 72 hour oral rechallenge period of ranitidine, was...


    pub_type: 杂志文章


    authors: Beaugerie L,Patey N,Brousse N

    更新日期:1995-11-01 00:00:00

  • Extrapancreatic necrosis without pancreatic parenchymal necrosis: a separate entity in necrotising pancreatitis?

    abstract:OBJECTIVE:In the revised Atlanta classification of acute pancreatitis, the term necrotising pancreatitis also refers to patients with only extrapancreatic fat necrosis without pancreatic parenchymal necrosis (EXPN), as determined on contrast-enhanced CT (CECT). Patients with EXPN are thought to have a better clinical o...


    pub_type: 杂志文章,多中心研究


    authors: Bakker OJ,van Santvoort H,Besselink MG,Boermeester MA,van Eijck C,Dejong K,van Goor H,Hofker S,Ahmed Ali U,Gooszen HG,Bollen TL,Dutch Pancreatitis Study Group.

    更新日期:2013-10-01 00:00:00

  • Use of an inert marker (phenol red) to improve accuracy in gastric secretion studies.

    abstract::Gastric secretion from 24 subjects was collected by continuous nasogastric aspiration during the plateau of secretion evoked by intravenous histamine diphosphate, 0.01 mg/kg/hr. Simultaneously, phenol red was instilled at a constant rate into the proximal part of the stomach. Concentrations of phenol red in 15-minute ...


    pub_type: 杂志文章


    authors: Hobsley M,Silen W

    更新日期:1969-10-01 00:00:00