Problems in diagnosing viral hepatitis.

abstract：:Hepatitis B and hepatitis C infections are important causes of end-stage liver disease and primary liver cancer. Successful antiviral treatment prior to the development of cirrhosis will prevent most of the morbidity and mortality associated with those infections. This can be achieved for a high proportion of patients...

journal_title：Gut

authors： Mutimer DJ,Lok A

更新日期：2012-05-01 00:00:00

abstract：:A simple technique for measuring gastrointestinal transit times using radioopaque pellets of barium-impregnated polythene has been developed and validated. A normal range has been established by studying 25 normal subjects; all passed the first marker within three days and most passed 80% of the markers within five da...

journal_title：Gut

authors： Hinton JM,Lennard-Jones JE,Young AC

更新日期：1969-10-01 00:00:00

abstract：OBJECTIVE:Osteopontin (OPN) has been found to be valuable in diagnosis and predicting the prognosis of a variety of malignancies. The aims of the present study are to evaluate the usefulness of plasma OPN level for predicting gastric cancer development, invasion and survival. PATIENTS AND METHODS:One hundred and thirt...

journal_title：Gut

authors： Wu CY,Wu MS,Chiang EP,Wu CC,Chen YJ,Chen CJ,Chi NH,Chen GH,Lin JT

更新日期：2007-06-01 00:00:00

abstract：:The metabolism of tauroursodeoxycholic acid orally administered and its effects on the bile acid pool of patients with asymptomatic/mildly symptomatic primary biliary cirrhosis is described. Patients were randomly assigned 500, 1000, or 1500 mg/day of tauroursodeoxycholate for six months. Biliary and serum bile acids ...

journal_title：Gut

authors： Setchell KD,Rodrigues CM,Podda M,Crosignani A

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Cholera toxin produces intestinal secretion by activation of the adenylate cyclase complex. However animal studies have shown 5-hydroxytryptamine may be released after exposure to cholera toxin, and thereby contribute to the secretory state. AIM:To determine whether cholera toxin releases 5-hydroxytryptamin...

journal_title：Gut

authors： Bearcroft CP,Perrett D,Farthing MJ

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND AIMS:To compare extracorporeal shock wave lithotripsy (ESWL) and laser induced shock wave lithotripsy (LISL) of retained bile duct stones to stone free rate, number of therapeutic sessions, and costs. PATIENTS:Thirty four patients were randomly assigned to either ESWL or LISL therapy. The main reasons f...

journal_title：Gut

authors： Jakobs R,Adamek HE,Maier M,Krömer M,Benz C,Martin WR,Riemann JF

更新日期：1997-05-01 00:00:00

abstract：:The epithelial-mesenchymal interface of the intestinal mucosa obviously plays an important role in supporting the mucosal architecture. Its significance for the process of migration and differentiation of the epithelial cells remains to be resolved. It consists of a basement membrane, the anchoring zone and the subepi...

journal_title：Gut

authors： Hahn U,Schuppan D,Hahn EG,Merker HJ,Riecken EO

更新日期：1987-01-01 00:00:00

abstract：:A case of spontaneous partial rupture of the normal large bowel causing a haemoperitoneum is described. No similar case appears to have been reported previously. ...

journal_title：Gut

authors： HOWE CT

更新日期：1960-12-01 00:00:00

abstract：:The prevalence of antibodies against hepatitis C virus (anti-HCV) among intravenous drug users (IVDU) has consistently been very high. Cross challenge studies in chimpanzees provide evidence that reinfection with different HCV strains may occur. In humans, reinfection with different HCV strains has been reported in mu...

journal_title：Gut

authors： Asselah T,Vidaud D,Doloy A,Boyer N,Martinot M,Vidaud M,Valla D,Marcellin P

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:The number of colonoscopies required to reach competency is not well established. The primary aim of this study was to determine the number of colonoscopies trainees need to perform to attain competency, defined by a caecal intubation rate (CIR) ≥90%. As competency depends on completion, we also investigated ...

journal_title：Gut

authors： Ward ST,Mohammed MA,Walt R,Valori R,Ismail T,Dunckley P

更新日期：2014-11-01 00:00:00

abstract：:The influence of dehydrocholate on bromsulphtalein relative-storage capacity, bilary transport maximum (Tm), and fractional transfer rates between plasma, liver and bile have been studied in unanaesthetized dogs. In six dogs, storage capacity, Tm, and fractional transfer rates from plasma to liver, liver to bile, and ...

journal_title：Gut

authors： Delage Y,Erlinger S,Duval M,Bpenhamou JP

更新日期：1975-02-01 00:00:00

abstract：:The endothelins are a group of three related peptides with two receptor subtypes, ET(A) and ET(B). Following the discovery of endothelin 1 as a potent vasoconstrictor, there has been intense interest in the role of endothelin on vascular function in liver disease. Speculation on the role of endothelin in the pathogene...

journal_title：Gut

authors： Moore K

更新日期：2004-02-01 00:00:00

abstract：:Cell cultures derived from Crohn's disease and control tissues were subjected to a series of tests designed to detect persistent, non-cytocidal virus infection. No evidence for any such infection was found, and it is concluded that persistent viral infection of gut tissues is unlikely to play a significant role in the...

journal_title：Gut

authors： Phillpotts RJ,Hermon-Taylor J,Teich NM,Brooke BN

更新日期：1980-03-01 00:00:00

abstract：:A case is described of non-necrotizing, epithelioid cell granulomatous synovitis of the ankle of a 22-year-old man with Crohn's disease. It appears to be the first published example of granulomatous arthritis in association with Crohn's disease. ...

journal_title：Gut

authors： Lindström C,Wramsby H,Ostberg G

更新日期：1972-04-01 00:00:00

abstract：BACKGROUND:"Probiotic" bacteria are effective in treating some inflammatory bowel diseases. However which bacteria confer benefit and mechanisms of action remain poorly defined. Dendritic cells, which are pivotal in early bacterial recognition, tolerance induction, and shaping of T cell responses, may be central in med...

journal_title：Gut

authors： Hart AL,Lammers K,Brigidi P,Vitali B,Rizzello F,Gionchetti P,Campieri M,Kamm MA,Knight SC,Stagg AJ

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Multiorgan failure is a severe life threatening state where present therapeutic approaches are suboptimal. Epidermal growth factor (EGF) is a potent stimulant of repair in in vitro and in vivo models. We therefore examined its potential beneficial effect in reducing mortality and injury induced by the noxiou...

journal_title：Gut

authors： Caballero ME,Berlanga J,Ramirez D,Lopez-Saura P,Gozalez R,Floyd DN,Marchbank T,Playford RJ

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Chronic HBV infection affects more than 250 million people worldwide and remains a global healthcare problem in part because we lack curative treatment. Sustained viral control requires HBV-specific T cells, but these become functionally impaired in chronic infection. Clinical evidence indicates that function...

journal_title：Gut

authors： Hoogeveen RC,Robidoux MP,Schwarz T,Heydmann L,Cheney JA,Kvistad D,Aneja J,Melgaço JG,Fernandes CA,Chung RT,Boonstra A,Kim AY,Baumert TF,Timm J,Lewis-Ximenez LL,Tonnerre P,Lauer GM

更新日期：2019-05-01 00:00:00

abstract：:One hundred patients who had undergone operation for duodenal ulcer (68 vagotomy and gastroenterostomy; seven vagotomy and pyloroplasty; 22 gastrectomy and three gastroenterostomy) 10 or more years previously each underwent endoscopy. Biopsies were taken and gastric juice aspirated for measurement of pH and nitrite co...

journal_title：Gut

authors： Watt PC,Sloan JM,Donaldson JD,Patterson CC,Kennedy TL

更新日期：1984-03-01 00:00:00

abstract：:The extent to which monitoring breath hydrogen excretion provides information concerning the entry of the residues of a solid test meal into the colon was investigated in 89 normal subjects, and 11 patients with the irritable bowel syndrome. The profile of breath hydrogen concentration showed an early peak, that occur...

journal_title：Gut

authors： Read NW,Al-Janabi MN,Bates TE,Holgate AM,Cann PA,Kinsman RI,McFarlane A,Brown C

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The choice of colorectal surgery in patients with familial adenomatous polyposis lies between the morbidity of proctocolectomy and ileum-pouch-anal anastomosis (IPAA) and the mortality from rectal cancer after total colectomy and ileorectal anastomosis (IRA). The aims of the present study were: (1) ...

journal_title：Gut

authors： Vasen HF,van Duijvendijk P,Buskens E,Bülow C,Björk J,Järvinen HJ,Bülow S

更新日期：2001-08-01 00:00:00

abstract：:Twenty one patients with diabetic peripheral neuropathy, 18 with idiopathic faecal incontinence and 11 normal controls were studied with techniques of mucosal electrosensitivity, rectal distension for the quantitative assessment of anorectal sensation, and manometric and electromyographic tests for the assessment of a...

journal_title：Gut

authors： Rogers J,Levy DM,Henry MM,Misiewicz JJ

更新日期：1988-06-01 00:00:00

abstract：:The role of the proximal and distal stomach in the emptying of solids and liquids from the stomach remains unclear. We have used a dual isotope technique to quantify proximal and distal stomach emptying of a solid (100 g of 99mTc labelled liver/ground beef) liquid (either 200 ml of normal saline (eight subjects) or 25...

journal_title：Gut

authors： Collins PJ,Houghton LA,Read NW,Horowitz M,Chatterton BE,Heddle R,Dent J

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVES:No trial has compared non-bismuth quadruple 'sequential' and 'concomitant' regimens in settings with increasing clarithromycin rates. The study aims to compare the effectiveness and safety of these therapies for Helicobacter pylori treatment. DESIGN:Prospective randomised clinical trial in 11 Spanish hospit...

journal_title：Gut

authors： McNicholl AG,Marin AC,Molina-Infante J,Castro M,Barrio J,Ducons J,Calvet X,de la Coba C,Montoro M,Bory F,Perez-Aisa A,Forné M,Gisbert JP,Participant Centres.

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Surgical management of extrahepatic cholestasis is frequently complicated by bacterial translocation and severe liver injury. The aim of this study was to clarify the involvement of Toll-like receptors (TLRs) in the pathogenesis of bacterial translocation and liver injury in obstructive cholestasis....

journal_title：Gut

authors： Ogawa A,Tagawa T,Nishimura H,Yajima T,Abe T,Arai T,Taniguchi M,Takeda K,Akira S,Nimura Y,Yoshikai Y

更新日期：2006-01-01 00:00:00

abstract：:Pregnancy and contraceptive steroids are associated with a raised incidence of cholesterol gall stone disease. In pregnancy there is an increase in the size of the gall bladder. Investigation of hepatobiliary function in man and mammals has not established if the enlarged gall bladder is simply dilated, or if the abso...

journal_title：Gut

authors： Rådberg G,Svanvik J

更新日期：1986-01-01 00:00:00

abstract：:During a four hour observation period vasoactive intestinal polypeptide (VIP) is released in increasing amounts from the feline small intestine exposed to cholera toxin. As VIP is known to be located almost exclusively in the intestinal nerves, the present findings strongly suggest that cholera toxin activates the ent...

journal_title：Gut

authors： Cassuto J,Fahrenkrug J,Jodal M,Tuttle R,Lundgren O

更新日期：1981-11-01 00:00:00

abstract：OBJECTIVES:Screening colonoscopy to monitor for early colitis-associated colon cancer (CAC) is difficult due to the aberrant mucosal patterns associated with long-standing colitis. The aim of this study was to develop a rapid fluorescent detection method for use during colonoscopy for improving the detection of CAC uti...

journal_title：Gut

authors： Mitsunaga M,Kosaka N,Choyke PL,Young MR,Dextras CR,Saud SM,Colburn NH,Sakabe M,Nagano T,Asanuma D,Urano Y,Kobayashi H

更新日期：2013-08-01 00:00:00

abstract：:Studies in the rat jejunum in vivo have shown that 5-hydroxytryptamine (5-HT) causes secretion of fluid and luminal release of prostaglandin (PG) E2. These effects can be blocked by indomethacin and ketanserin, which suggests that PGE2 may be an important intermediate in the transduction mechanism leading to 5-HT indu...

journal_title：Gut

authors： Munck LK,Mertz-Nielsen A,Westh H,Bukhave K,Beubler E,Rask-Madsen J

更新日期：1988-10-01 00:00:00

abstract：:The incidence of small intestinal colonization in unoperated duodenal ulcer patients was low and similar to that in the normal population. The majority of patients seven to 10 days following truncal vagotomy and drainage were colonized whereas none of a control group of patients following simple closure of a perforate...

journal_title：Gut

authors： Browning GG,Buchan KA,Mackay C

更新日期：1974-02-01 00:00:00

abstract：BACKGROUND:Collagenous colitis and lymphocytic colitis present with a similar clinical picture. Whether these conditions are separate entities or whether they represent different pathological stages of the same condition is an unresolved issue. PATIENT:This is a case of collagenous colitis following a fulminant course...

journal_title：Gut

authors： Bowling TE,Price AB,al-Adnani M,Fairclough PD,Menzies-Gow N,Silk DB

更新日期：1996-05-01 00:00:00