A case of spontaneous rupture of the normal large bowel causing haemoperitoneum.

abstract：:The frequency of gastric Crohn's disease has been considered low. This study was undertaken to determine the prevalence of chronic gastritis and Helicobacter pylori infection in patients with Crohn's disease. Oesophagogastroduodenoscopy was performed on 62 consecutive patients suffering from ileocolonic Crohn's diseas...

journal_title：Gut

authors： Halme L,Kärkkäinen P,Rautelin H,Kosunen TU,Sipponen P

更新日期：1996-03-01 00:00:00

abstract：:The carrier rate of hepatitis B virus (HBV) in black Africans averages 10.4% throughout the continent. Even within each country, however, there may be wide variations. HBV carriage in black Africans is largely established in early childhood, mostly through horizontal transmission. Perinatal transmission also occurs bu...

journal_title：Gut

authors： Kew MC

更新日期：1996-01-01 00:00:00

abstract：:The experience of The Middlesex Hospital in the investigation and management of chronic intestinal arterial occlusion (IAO) over a 20 year period is presented. Of some 100 patients referred only 28 were found to have IAO and these were critically evaluated in terms of insorptive and exsorptive function. No relation wa...

journal_title：Gut

authors： Marston A,Clarke JM,Garcia Garcia J,Miller AL

更新日期：1985-07-01 00:00:00

abstract：:Four different dosage regimens of interferon (IFN) alfa-2b (3 million units (MU) three times weekly for three months, 3 MU three times weekly for six months, 6 MU two times weekly for six months, and 6 MU three times weekly for six months) were compared in patients with chronic hepatitis C. There was no significant di...

journal_title：Gut

authors： De Bac C,Grimaldi F,Clementi C,Duca F,Livoli D,Taliani G

更新日期：1993-01-01 00:00:00

abstract：:Bowel function was assessed in 51 subjects: 10 women and seven men who habitually consumed an omnivorous, vegetarian, or vegan diet. The subjects on these diets had a mean intake of fibre of 23 g, 37 g, and 47 g respectively. Mean transit times were variable and not significantly different between the groups. Vegans, ...

journal_title：Gut

authors： Davies GJ,Crowder M,Reid B,Dickerson JW

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:To characterise gut microbiome in patients with hepatocellular carcinoma (HCC) and evaluate the potential of microbiome as non-invasive biomarkers for HCC. DESIGN:We collected 486 faecal samples from East China, Central China and Northwest China prospectively and finally 419 samples completed Miseq sequencin...

journal_title：Gut

authors： Ren Z,Li A,Jiang J,Zhou L,Yu Z,Lu H,Xie H,Chen X,Shao L,Zhang R,Xu S,Zhang H,Cui G,Chen X,Sun R,Wen H,Lerut JP,Kan Q,Li L,Zheng S

更新日期：2019-06-01 00:00:00

abstract：:Fasting and postprandial plasma concentrations of glycine and taurine conjugates of cholic, chenodeoxycholic, and deoxycholic acid were measured by a high pressure liquid chromatography-enzymatic assay in nine healthy subjects. The mean value of each bile acid concentration increased significantly (2.4-4.7 times) in t...

journal_title：Gut

authors： Linnet K

更新日期：1983-03-01 00:00:00

abstract：:Patients with primary biliary cirrhosis have a defect in the receptor mediated clearance of complement coated erythrocytes by fixed macrophages of the reticuloendothelial system. To investigate the probable mechanism of this defect peripheral blood monocytes were isolated from nine patients with primary biliary cirrho...

journal_title：Gut

authors： Minuk GY,Vergalla J,Hanson RG,Hoofnagle JH,Frank MM,Jones EA

更新日期：1986-03-01 00:00:00

abstract：:Eluates were prepared by high salt extraction from normal colonic mucosa and adenocarcinomatous tissue from 28 patients, eight more from unmatched colonic tissue and five from patients with other gastrointestinal disease. Immunoglobulins were detected by ELISA: IgG was present in 24% eluates from normal colon and 21% ...

journal_title：Gut

authors： Grail A,Norval M

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:The molecular mechanisms mediating the antiproliferative effects of interferon alpha on human pancreatic carcinoma cells are poorly understood. AIM:To characterise the effects of interferon alpha on protein kinase C isoenzyme expression in interferon alpha sensitive and resistant human pancreatic tumour cel...

journal_title：Gut

authors： Rosewicz S,Weder M,Kaiser A,Riecken EO

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:Osteopontin (OPN) has been found to be valuable in diagnosis and predicting the prognosis of a variety of malignancies. The aims of the present study are to evaluate the usefulness of plasma OPN level for predicting gastric cancer development, invasion and survival. PATIENTS AND METHODS:One hundred and thirt...

journal_title：Gut

authors： Wu CY,Wu MS,Chiang EP,Wu CC,Chen YJ,Chen CJ,Chi NH,Chen GH,Lin JT

更新日期：2007-06-01 00:00:00

abstract：:In dogs with either vagally innervated or denervated pouches, the acid responses to a standard meal, a meal which bypassed the greater part of the small bowel, and a meal introduced directly into the small intestine were measured before and after exclusion of 75% of the small bowel.After intestinal exclusion an increa...

journal_title：Gut

authors： Buxton B,Wasunna AE,Saunders J,Gillespie IE

更新日期：1972-07-01 00:00:00

abstract：:The aims of the present study were to determine the relative amplitudes of intragastric motor responses evoked by different vagal branches and to establish whether the effects of acute or chronic vagotomy could be predicted from these data. Intragastric pressure responses to electrical stimulation of the vagus were me...

journal_title：Gut

authors： Andrews PL,Lawes IN,Bower AJ

更新日期：1980-10-01 00:00:00

abstract：OBJECTIVES:Patients with gallbladder carcinoma (GBC) lack effective treatment methods largely due to the inadequacy of both molecular characterisation and potential therapeutic targets. We previously uncovered a spectrum of genomic alterations and identified recurrent mutations in the ErbB pathway in GBC. Here, we aime...

journal_title：Gut

authors： Li M,Liu F,Zhang F,Zhou W,Jiang X,Yang Y,Qu K,Wang Y,Ma Q,Wang T,Bai L,Wang Z,Song X,Zhu Y,Yuan R,Gao Y,Liu Y,Jin Y,Li H,Xiang S,Ye Y,Zhang Y,Jiang L,Hu Y,Hao Y,Lu W,Chen S,Gu J,Zhou J,Gong W,Z

更新日期：2019-06-01 00:00:00

abstract：:The problems associated with recurrent Crohn's disease were examined in a series of 168 patients who had undergone primary resection for this condition at the General Infirmary at Leeds from 1939 to 1968 inclusive. The overall recurrence rate was 34.2%. The risk of recurrence was less in patients with involvement main...

journal_title：Gut

authors： De Dombal FT,Burton I,Goligher JC

更新日期：1971-07-01 00:00:00

abstract：:The value of the bipolar electrocoagulator in the haemostasis of bleeding ulcers is controversial. We have therefore investigated the effect of different coagulation times on vessel weld strength achieved by the bipolar device. Welds were then made in vessels of known diameter using a standard 10F endoscopic haemostat...

journal_title：Gut

authors： Harrison JD,Morris DL

更新日期：1991-02-01 00:00:00

abstract：:Seventeen paediatric patients with immunodeficiency syndromes (10 with selective IgA deficiency, four with panhypogammaglobulinaemia, and three with selective T cell deficiency) were investigated for bacterial overgrowth of the small intestine and gut permeability to macromolecules. Five of 12 patients showed viable b...

journal_title：Gut

authors： Pignata C,Budillon G,Monaco G,Nani E,Cuomo R,Parrilli G,Ciccimarra F

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND/AIMS:To investigate the prognostic values of putative hepatic stem/progenitor cell (HSC/HPC) biomarkers in patients with hepatocellular carcinoma (HCC). METHODS:Fourteen biomarkers related to HSCs/HPCs or tumour angiogenesis were assessed by qRT-PCR and then validated by tissue microarrays (TMAs) in three i...

journal_title：Gut

authors： Yang XR,Xu Y,Yu B,Zhou J,Qiu SJ,Shi GM,Zhang BH,Wu WZ,Shi YH,Wu B,Yang GH,Ji Y,Fan J

更新日期：2010-07-01 00:00:00

abstract：AIMS:To study fracture rates and risk factors for fractures in patients with Crohn's disease and ulcerative colitis. METHODS:998 self administered questionnaires were issued to members of the Danish Colitis/Crohn Association, and 1000 questionnaires were issued to randomly selected control subjects. 845 patients (84.5...

journal_title：Gut

authors： Vestergaard P,Krogh K,Rejnmark L,Laurberg S,Mosekilde L

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Interleukin 8 (IL-8) has recently been proposed to have an important role in mediating the development of the systemic sequelae associated with severe acute pancreatitis. AIMS:To define the role of IL-8 in acute pancreatitis by neutralising its effects with a monoclonal anti-IL-8 antibody (WS-4), in a rabbi...

journal_title：Gut

authors： Osman MO,Kristensen JU,Jacobsen NO,Lausten SB,Deleuran B,Deleuran M,Gesser B,Matsushima K,Larsen CG,Jensen SL

更新日期：1998-08-01 00:00:00

abstract：:Our life expectancy is increasing, leading to a rise in the ageing population. Ageing is associated with a decline in physiological function and adaptive capacity. Altered GI physiology can affect the amount and types of nutrients digested and absorbed as well as impact the intestinal microbiota. The intestinal microb...

journal_title：Gut

authors： An R,Wilms E,Masclee AAM,Smidt H,Zoetendal EG,Jonkers D

更新日期：2018-12-01 00:00:00

abstract：:The increase in activities of hepatic thymidylate synthetase (EC 2.1.1.45) and thymidine kinase (EC 2.7.1.21), which catalyse the formation of thymidylate through the de novo and salvage pathways, respectively, were significantly suppressed during liver regeneration in rats which were given glucocorticoids (hydrocorti...

journal_title：Gut

authors： Tsukamoto I,Kojo S

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori strains possessing the cagA gene are thought to induce interleukin 8 (IL-8) in gastric mucosa. However, it is still unclear whether a relation exists between the cagA gene and the expression patterns of cytokines other than IL-8. AIMS:To investigate the relation between the cagA gene and...

journal_title：Gut

authors： Yamaoka Y,Kita M,Kodama T,Sawai N,Kashima K,Imanishi J

更新日期：1997-10-01 00:00:00

abstract：:The disposition of antipyrine following oral administration of 1200 mg has been investigated in 10 patients with histologically confirmed hepatosplenic schistosomiasis and 11 normal subjects living in Sudan. Drug metabolising activity as assessed by antipyrine clearance was similar in patients when compared with norma...

journal_title：Gut

authors： Homeida M,Salih SY,Branch RA

更新日期：1978-09-01 00:00:00

abstract：:Extracellular electrical and contractile activities were recorded in vitro from strips of human colonic smooth muscle obtained at the time of surgery. Serosal electrical activity of longitudinally oriented strips from the taenia and intertaenial region was characterised by continuous oscillation at a frequency of 28 +...

journal_title：Gut

authors： Gill RC,Cote KR,Bowes KL,Kingma YJ

更新日期：1986-03-01 00:00:00

abstract：:The hormones secretin and cholecystokinin-pancreozymin (CCK) have been shown to release brush-border alkaline phosphatase into the small-intestinal lumen in the human subject. In contrast to the disaccharidases, large amounts of alkaline phosphatase are present in human duodenal juice. The range has been established i...

journal_title：Gut

authors： Warnes TW,Hine P,Kay G

更新日期：1974-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The gastrointestinal microflora exerts a barrier effect against enteropathogens. The aim of this study was to examine if bifidobacteria, a major species of the human colonic microflora, participates in the barrier effect by developing antimicrobial activity against enterovirulent bacteria. METHODS:...

journal_title：Gut

authors： Liévin V,Peiffer I,Hudault S,Rochat F,Brassart D,Neeser JR,Servin AL

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Helicobacter pylori (H pylori) infection is a major risk factor in the development of distal gastric adenocarcinoma. Development of the invasive phenotype is associated with the phenomenon of epithelial:mesenchymal transition (EMT). Soluble heparin-binding epidermal growth factor (HB-EGF) has been i...

journal_title：Gut

authors： Yin Y,Grabowska AM,Clarke PA,Whelband E,Robinson K,Argent RH,Tobias A,Kumari R,Atherton JC,Watson SA

更新日期：2010-08-01 00:00:00

abstract：:Although changes in T lymphocyte subset distribution in the peripheral blood of patients infected with human immunodeficiency virus (HIV) are well defined it is not known whether these changes reflect changes in lymphoid compartments clearly involved in HIV related disease like the intestinal mucosa. This study analys...

journal_title：Gut

authors： Schneider T,Jahn HU,Schmidt W,Riecken EO,Zeitz M,Ullrich R

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Cirrhotic patients with hepatocellular carcinoma (HCC) frequently have impaired glucose metabolism. AIMS:To investigate whether impaired glucose metabolism affects the growth rate of the tumour. PATIENTS AND METHODS:Tumour doubling time (DT), assessed by ultrasound imaging analysis, was measured in 60 pati...

journal_title：Gut

authors： Saito K,Inoue S,Saito T,Kiso S,Ito N,Tamura S,Watanabe H,Takeda H,Misawa H,Togashi H,Matsuzawa Y,Kawata S

更新日期：2002-07-01 00:00:00