Peripheral functional organisation of vagally evoked gastric motor responses in the ferret.

abstract：BACKGROUND:Dyspepsia and irritable bowel syndrome are suitable conditions for assessment of quality of life. Their similarities justify the elaboration of a single specific questionnaire for the two conditions. AIMS:To examine the process leading to the validation of the psychometric properties of the functional diges...

journal_title：Gut

authors： Chassany O,Marquis P,Scherrer B,Read NW,Finger T,Bergmann JF,Fraitag B,Geneve J,Caulin C

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:There is considerable evidence indicating that the severity of hepatic damage in individuals with cholestatic liver disease is causally associated with the extent of intrahepatic oxidative stress. Increased levels or accelerated generation of reactive oxygen species and toxic degradative products of lipid pe...

journal_title：Gut

authors： Ljubuncic P,Tanne Z,Bomzon A

更新日期：2000-11-01 00:00:00

abstract：:The possibility that proliferative instability around a healing anastomosis promotes carcinogenesis was tested in 234 male Sprague-Dawley rats. Animals received the first of five weekly injections of azoxymethane (total dose 50 mg/kg) either immediately after transection of the descending colon or at 2, 4, 8, and 12 w...

journal_title：Gut

authors： Roe R,Fermor B,Williamson RC

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Chronic idiopathic intestinal pseudo-obstruction (CIIP) is characterised by severe impairment of intestinal propulsive motility that mimics bowel obstruction. JC virus (JCV) is a polyomavirus that can infect brain glial cells causing a fatal disease, but may also be found throughout the normal gastr...

journal_title：Gut

authors： Selgrad M,De Giorgio R,Fini L,Cogliandro RF,Williams S,Stanghellini V,Barbara G,Tonini M,Corinaldesi R,Genta RM,Domiati-Saad R,Meyer R,Goel A,Boland CR,Ricciardiello L

更新日期：2009-01-01 00:00:00

abstract：:The aim of this study is to assess the value of jejunal manometry in the diagnosis of subacute mechanical obstruction distal to the proximal small bowel. In a retrospective review of 850 manometric tracings carried out in patients with unexplained nausea, vomiting, abdominal pain or altered bowel movements, 16 tracing...

journal_title：Gut

authors： Camilleri M

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND AIM:Accumulation and infiltration by neutrophil granulocytes is a prominent feature in the local inflammatory process in ulcerative colitis (UC). The present study was performed to evaluate human neutrophil lipocalin (HNL) as a specific neutrophil marker in the inflamed lesions of the colon and rectum in...

journal_title：Gut

authors： Carlson M,Raab Y,Sevéus L,Xu S,Hällgren R,Venge P

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:In a previous hospital based study, we suggested that undiagnosed coeliac disease has a prevalence, among pregnant women, of 1:80, and is a cause of unfavourable outcome of pregnancy. AIMS:In order to confirm or dismiss this hypothesis, which has significant public health implications, we carried out a larg...

journal_title：Gut

authors： Greco L,Veneziano A,Di Donato L,Zampella C,Pecoraro M,Paladini D,Paparo F,Vollaro A,Martinelli P

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND AIM:To clarify the roles of Helicobacter pylori cytotoxin in gastric atrophy, the cytotoxin positive rate and cytotoxin activity in Fukui and Okinawa, where the prevalence of atrophic gastritis and gastric cancer risk are quite different, were studied. MATERIALS:Seventy three strains from Fukui and 51 f...

journal_title：Gut

authors： Ito S,Azuma T,Murakita H,Hirai M,Miyaji H,Ito Y,Ohtaki Y,Yamazaki Y,Kuriyama M,Keida Y,Kohli Y

更新日期：1996-12-01 00:00:00

abstract：:It has been proposed that anti-inflammatory actions of corticosteroids rely on promotion of a natural peptide phospholipase A2 inhibitor, lipocortin, but in vivo effects on arachidonic acid metabolism have not been shown. Equilibrium dialysis of the rectum in patients with ulcerative colitis was used to determine whet...

journal_title：Gut

authors： Lauritsen K,Laursen LS,Bukhave K,Rask-Madsen J

更新日期：1987-09-01 00:00:00

abstract：:The plasma clearance and the liver uptake of intravenously administered (64)Cu were significantly impaired in four patients with Wilson's disease. These defects were unlikely to be simply expressions of the high liver copper concentration as the plasma clearance and hepatic uptake of (64)Cu were normal in four patient...

journal_title：Gut

authors： Smallwood RA,McIlveen B,Rosenoer VM,Sherlock S

更新日期：1971-02-01 00:00:00

abstract：:A 45 year old man is described with Whipple's disease who presented with weight loss, lethargy, and ascites. He subsequently developed fever and a mass in the neck, but died despite antibiotic treatment and nutritional support. Necropsy showed extraintestinal lymphoma. ...

journal_title：Gut

authors： Gillen CD,Coddington R,Monteith PG,Taylor RH

更新日期：1993-11-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death and is currently the main event leading to death in patients with cirrhosis. Evolving information suggests that the metabolic syndrome with non-alcoholic liver disease may be an important cause of HCC in addition to viral hepatitis and...

journal_title：Gut

authors： Bruix J,Gores GJ,Mazzaferro V

更新日期：2014-05-01 00:00:00

abstract：:Clarithromycin, a new and well tolerated, acid stable macrolide antibiotic, has a similar antimicrobial spectrum to erythromycin but a better in vitro MIC90 (0.03 microgram/l-1) against Helicobacter pylori (H pylori). This study aimed at determining the eradication rate using clarithromycin 500 mg thrice daily and ome...

journal_title：Gut

authors： Logan RP,Gummett PA,Schaufelberger HD,Greaves RR,Mendelson GM,Walker MM,Thomas PH,Baron JH,Misiewicz JJ

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:A high body mass index (BMI) is associated with an increased risk for severe liver disease. It is unclear if this risk differs across BMI categories, and if the association is partially attributed to development of type 2 diabetes mellitus (T2DM). DESIGN:We used register data from more than 1.2 million Swedi...

journal_title：Gut

authors： Hagström H,Tynelius P,Rasmussen F

更新日期：2018-08-01 00:00:00

abstract：:Lymphocytes obtained after enzymatic digestion of intestinal biopsies from patients with coeliac disease were examined for the presence of gliadin specific antibody secreting cells by means of the ELISPOT technique. This technique permits enumeration of gliadin antibody secreting immunocytes, differentiated with regar...

journal_title：Gut

authors： Lycke N,Kilander A,Nilsson LA,Tarkowski A,Werner N

更新日期：1989-01-01 00:00:00

abstract：:Ileal disease or resection causes bile salt malabsorption and a reduction in the bile salt content of bile. Since cholesterol solubility requires adequate bile salt concentrations, depletion of the bile salt content of bile might, therefore, jeopardize cholesterol solubility and predispose to cholesterol gallstone for...

journal_title：Gut

authors： Dowling RH,Bell GD,White J

更新日期：1972-06-01 00:00:00

abstract：BACKGROUND:Several animal models for human ulcerative colitis (UC) associated neoplasia have been reported. However, most neoplasias developed in these models have morphological and genetic characteristics different from UC associated neoplasia. AIMS:To establish a new colitis associated neoplasia model in p53 deficie...

journal_title：Gut

authors： Fujii S,Fujimori T,Kawamata H,Takeda J,Kitajima K,Omotehara F,Kaihara T,Kusaka T,Ichikawa K,Ohkura Y,Ono Y,Imura J,Yamaoka S,Sakamoto C,Ueda Y,Chiba T

更新日期：2004-05-01 00:00:00

abstract：:Computed tomography detected the presence of dilated ducts in 15 of 18 cases with extrahepatic obstructive jaundice and demonstrated the obstructing lesion in 18 out of 25. The cause of the obstruction was detected in the absence of duct dilatation, and calculi which were radiolucent on conventional radiographs were d...

journal_title：Gut

authors： Morris A,Fawcitt RA,Wood R,Forbes WS,Isherwood I,Marsh MN

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:The prognosis of patients with hepatocellular carcinoma (HCC) remains poor, and new alternative treatments are needed. AIMS:To comparatively test the angiostatic and antitumour effects of adenoviral gene transfer of angiostatin (PlgK1-4, amino acids 1-440) and full kringles 1-5 (PlgK1-5, amino acids 1-546) ...

journal_title：Gut

authors： Schmitz V,Raskopf E,Gonzalez-Carmona MA,Vogt A,Rabe C,Leifeld L,Kornek M,Sauerbruch T,Caselmann WH

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:An increasing number of case reports indicate potential nephrotoxicity of 5-aminosalicylic acid (5-ASA), which shares similarities with the chemical structures of both phenacetin and acetylsalicylic acid. AIM:In a point prevalence study the occurrence of sensitive indices indicative of early kidney malfunct...

journal_title：Gut

authors： Schreiber S,Hämling J,Zehnter E,Howaldt S,Daerr W,Raedler A,Kruis W

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Low grade dysplasia (LGD) is believed to predispose to colorectal cancer (CRC), and proctocolectomy has been advocated when this is identified. Between 1978 and 1990, 160 patients with longstanding extensive ulcerative colitis (UC) were recruited for annual colonoscopic surveillance and 40 developed...

journal_title：Gut

authors： Lim CH,Dixon MF,Vail A,Forman D,Lynch DA,Axon AT

更新日期：2003-08-01 00:00:00

abstract：:The records of 113 consecutive patients with a suspected gastrointestinal motility disorder referred between January 1988 and July 1991 were retrospectively reviewed. The aims were to identify the prevalence of autonomic dysfunction in those with or without associated neurological disease and to determine the diagnost...

journal_title：Gut

authors： Bharucha AE,Camilleri M,Low PA,Zinsmeister AR

更新日期：1993-03-01 00:00:00

abstract：:Vagal and spinal afferents represent the information superhighways that convey sensory information from the gut to the central nervous system. These afferents are sensitive to both mechanical and chemical stimuli. Vagal afferents terminate in the muscle layers and in the mucosa. Muscle afferents are activated at physi...

journal_title：Gut

authors： Grundy D

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:The potential of endoscopic mucosal resection (EMR) for treating flat dysplastic lesions in chronic ulcerative colitis (CUC) has not been addressed so far. Historically, such lesions were referred for colectomy. Furthermore, there are only limited data to support endoscopic resection of exophytic adenoma-lik...

journal_title：Gut

authors： Hurlstone DP,Sanders DS,Atkinson R,Hunter MD,McAlindon ME,Lobo AJ,Cross SS,Thomson M

更新日期：2007-06-01 00:00:00

abstract：:In two patients presenting with mild intestinal symptoms, rectal spirochaetosis was the only morphological abnormality diagnosed by light microscopy. A re-evaluation of the morphological changes using electron microscopy and immunohistochemistry showed certain unusual features: the microorganisms were observed within ...

journal_title：Gut

authors： Gebbers JO,Ferguson DJ,Mason C,Kelly P,Jewell DP

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:Many patients with irritable bowel syndrome IBS not only have abdominal pain but also may suffer from visceral hypersensitivity and heighted visceral nociception. Moreover, IBS has few effective therapeutic agents and mechanisms of disease are unclear. Our goals were to (i) identify microRNA (miRNA) expressio...

journal_title：Gut

authors： Zhou Q,Yang L,Larson S,Basra S,Merwat S,Tan A,Croce C,Verne GN

更新日期：2016-05-01 00:00:00

abstract：:The prevalence of antibodies against hepatitis C virus (anti-HCV) among intravenous drug users (IVDU) has consistently been very high. Cross challenge studies in chimpanzees provide evidence that reinfection with different HCV strains may occur. In humans, reinfection with different HCV strains has been reported in mu...

journal_title：Gut

authors： Asselah T,Vidaud D,Doloy A,Boyer N,Martinot M,Vidaud M,Valla D,Marcellin P

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are important in hepatic pathophysiology and the development of liver cancer. OBJECTIVE:To explore miRNAs that are regulated with the progression of liver fibrosis caused by chronic liver disease. DESIGN:The regulated miRNAs in human livers infected with hepatitis C virus were identified...

journal_title：Gut

authors： Ogawa T,Enomoto M,Fujii H,Sekiya Y,Yoshizato K,Ikeda K,Kawada N

更新日期：2012-11-01 00:00:00

abstract：:In a study of low dose interferon alfa-2b in 587 patients expected to show a good response to treatment, 76-87% patients in different countries had alanine amino-transferase activities returned to normal after four months' treatment, 49-72% were negative for hepatitis B virus (HBV)-DNA, 51-66% were negative for hepati...

journal_title：Gut

authors： Mauracher E

更新日期：1993-01-01 00:00:00

abstract：:On three occasions, a 63 year old housewife with hyperthyroidism developed a reaction which included fever, pruritus, malaise, and, on one occasion, jaundice one to 17 days after taking carbimazole. Challenge with carbimazole was followed within 12 hours by abdominal pain, pruritus, and increased serum transaminase le...

journal_title：Gut

authors： Lunzer M,Huang SN,Ginsburg J,Ahmed M,Sherlock S

更新日期：1975-11-01 00:00:00