Low dose interferon alfa-2b for chronic hepatitis B in Asian countries.

abstract：:To examine socioeconomic factors, dietary and other personal habits, and medical history as risk factors for ulcerative colitis, we studied 167 (98%) of all prevalent cases of ulcerative colitis diagnosed in Uppsala county from 1945 to 1964 and 167 age and sex matched population controls. Ulcerative colitis patients w...

journal_title：Gut

authors： Samuelsson SM,Ekbom A,Zack M,Helmick CG,Adami HO

更新日期：1991-12-01 00:00:00

abstract：:CLINICAL PRESENTATION: A 51-year-old man, who had no previous disease, underwent a screening oesophagogastroduodenoscopy, which revealed multiple yellowish lesions in the middle thoracic oesophagus. All lesions were ≤3 mm in size and slightly elevated. Each lesion showed one or two white protrusions on the surface (fi...

journal_title：Gut

authors： Hamada K,Yamasaki Y,Kubota JI,Okada H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Multiorgan failure is a severe life threatening state where present therapeutic approaches are suboptimal. Epidermal growth factor (EGF) is a potent stimulant of repair in in vitro and in vivo models. We therefore examined its potential beneficial effect in reducing mortality and injury induced by the noxiou...

journal_title：Gut

authors： Caballero ME,Berlanga J,Ramirez D,Lopez-Saura P,Gozalez R,Floyd DN,Marchbank T,Playford RJ

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Hepatocellular carcinoma (HCC) frequently results from synergism between chemical and infectious liver carcinogens. Worldwide, the highest incidence of HCC is in regions endemic for the foodborne contaminant aflatoxin B1 (AFB1) and hepatitis B virus (HBV) infection. Recently, gut microbes have been ...

journal_title：Gut

authors： Fox JG,Feng Y,Theve EJ,Raczynski AR,Fiala JL,Doernte AL,Williams M,McFaline JL,Essigmann JM,Schauer DB,Tannenbaum SR,Dedon PC,Weinman SA,Lemon SM,Fry RC,Rogers AB

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Coeliac disease (CD) is triggered by an abnormal reaction to gluten. Peptides resulting from partially digested gluten of wheat, barley or rye cause inflammation of the small intestinal mucosa. Previous contradictory studies suggest that oats may trigger the abnormal immunological response in patien...

journal_title：Gut

authors： Comino I,Real A,de Lorenzo L,Cornell H,López-Casado MÁ,Barro F,Lorite P,Torres MI,Cebolla A,Sousa C

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:Polycystic liver diseases (PCLDs) are genetic disorders characterised by progressive bile duct dilatation and/or cyst development. Their pathogenesis is a consequence of hyperproliferation, hypersecretion and microRNA alterations in cholangiocytes. Here we evaluate the role of matrix metalloproteases (MMPs) i...

journal_title：Gut

authors： Urribarri AD,Munoz-Garrido P,Perugorria MJ,Erice O,Merino-Azpitarte M,Arbelaiz A,Lozano E,Hijona E,Jiménez-Agüero R,Fernandez-Barrena MG,Jimeno JP,Marzioni M,Marin JJ,Masyuk TV,LaRusso NF,Prieto J,Bujanda L,Banales JM

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Dietary folate is believed to protect against colorectal cancer (CRC). However, few studies have addressed the role of circulating levels of folate. The aim of this study was to relate prediagnostic plasma folate and homocysteine concentrations and the methylenetetrahydrofolate reductase (MTHFR) 677...

journal_title：Gut

authors： Van Guelpen B,Hultdin J,Johansson I,Hallmans G,Stenling R,Riboli E,Winkvist A,Palmqvist R

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Increased infertility in women has been reported after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis but reported infertility rates vary substantially. AIMS:(1) To perform a systematic review and meta-analysis of the relative risk of infertility post-IPAA compared with medical management; (2) t...

journal_title：Gut

authors： Waljee A,Waljee J,Morris AM,Higgins PD

更新日期：2006-11-01 00:00:00

abstract：:To assist in the prediction of variceal bleeding we examined 12 clinical, endoscopic and haemodynamic variables in 126 patients with portal hypertension (72 bleeders and 54 non-bleeders). Multiple regression and discriminant analysis were utilised for 101 patients. Stepwise regression among the 12 variables explained ...

journal_title：Gut

authors： Sarin SK,Sundaram KR,Ahuja RK

更新日期：1989-12-01 00:00:00

abstract：:Infusion of fat into the ileum slows small bowel transit and increases absorption of a carbohydrate meal. Paired studies were undertaken to investigate the effect of adding fat to the diet on gastrointestinal transit and absorption in eight people with terminal ileostomies. Each subject ate a daily diet that contained...

journal_title：Gut

authors： Higham SE,Read NW

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Recently identified ABCG5/8 transporters are responsible in part for the different absorption rates of campesterol, sitosterol, and cholesterol. These transporters are also expressed in the liver and might regulate biliary sterol secretion. AIMS:This study was therefore conducted to determine the biliary se...

journal_title：Gut

authors： Sudhop T,Sahin Y,Lindenthal B,Hahn C,Lüers C,Berthold HK,von Bergmann K

更新日期：2002-12-01 00:00:00

abstract：:It has been demonstrated that cardiac output and pulmonary, gastroduodenal, pancreatic, and splenic blood flow increases after portacaval shunt operations. This report concerns a study of cerebral haemodynamics and metabolism in eight patients with cirrhosis of the liver, examined both before and after portacaval surg...

journal_title：Gut

authors： Bianchi Porro G,Maiolo AT,Della Porta P

更新日期：1969-11-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between Mediterranean diet and risk of later-onset Crohn's disease (CD) or ulcerative colitis (UC). DESIGN:We conducted a prospective cohort study of 83 147 participants (age range: 45-79 years) enrolled in the Cohort of Swedish Men and Swedish Mammography Cohort. A validated food...

journal_title：Gut

authors： Khalili H,Håkansson N,Chan SS,Chen Y,Lochhead P,Ludvigsson JF,Chan AT,Hart AR,Olén O,Wolk A

更新日期：2020-09-01 00:00:00

abstract：:An estimated 7.5 million individuals in England and Wales are actively infected with Helicobacter pylori and hence knowledge of local resistance rates is of growing importance. Also, information on strain resistance following treatment failure is crucial in selecting an appropriate regimen as the development of bacter...

journal_title：Gut

authors： Owen RJ

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The mechanisms of aspirin induced gastroduodenal injury are not fully understood. Aspirin induces the release of reactive oxygen metabolites in animal models, which may contribute to mucosal injury. AIMS:To investigate the effects of aspirin administered with placebo or antioxidants on gastric mucosal react...

journal_title：Gut

authors： McAlindon ME,Muller AF,Filipowicz B,Hawkey CJ

更新日期：1996-04-01 00:00:00

abstract：:Synthetic 13-norleucine-motilin (13-nle-motilin), structural and biological analogue of the naturally-occurring duodenal polypeptide, motilin, is known to stimulate antral and duodenal motor activity in vitro, but delays gastric emptying in man. In this study the direct actions of the synthetic polypeptide on myoelect...

journal_title：Gut

authors： Green WE,Ruppin H,Wingate DL,Domschke W,Wünsch DE,Demling L,Ritchie HD

更新日期：1976-05-01 00:00:00

abstract：:Ileal permeability to different sized polyethyleneglycols (590-942 dalton PEG) was investigated peroperatively in 11 patients with Crohn's disease and seven with colonic carcinoma. A 15 cm ileal segment was converted into a tied loop, in which the PEG's were deposited. Absorption from the ileal segment was then measur...

journal_title：Gut

authors： Olaison G,Leandersson P,Sjödahl R,Tagesson C

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori affects gastric epithelium integrity by acceleration of apoptosis. However, it remains unclear what product of the bacteria causes apoptosis, or whether or not the apoptosis is involved in the development of ulcers. AIMS:To elucidate the factor from H pylori that causes acceleration of a...

journal_title：Gut

authors： Kohda K,Tanaka K,Aiba Y,Yasuda M,Miwa T,Koga Y

更新日期：1999-04-01 00:00:00

abstract：:A patient with myelofibrosis developed repeated gastrointestinal haemorrhage from the small intestine, which was found to be infiltrated with extramedullary haemopoiesis. Nineteen months later he presented with subacute intestinal obstruction; radiology and laparotomy documented progressive infiltration of the small b...

journal_title：Gut

authors： Sharma BK,Pounder RE,Cruse JP,Knowles SM,Lewis AA

更新日期：1986-07-01 00:00:00

abstract：:Central reading, that is, independent, off-site, blinded review or reading of imaging endpoints, has been identified as a crucial component in the conduct and analysis of inflammatory bowel disease clinical trials. Central reading is the final step in a workflow that has many parts, all of which can be improved. Furth...

journal_title：Gut

authors： Gottlieb K,Daperno M,Usiskin K,Sands BE,Ahmad H,Howden CW,Karnes W,Oh YS,Modesto I,Marano C,Stidham RW,Reinisch W

更新日期：2021-02-01 00:00:00

abstract：:A retrospective survey was undertaken of 228 resected Meckel's diverticula to determine if there was any evidence of Campylobacter pylori infection in diverticula containing gastric mucosa. Among the 65 diverticula with gastric mucosa one was heavily infected with organisms having the morphological appearances of C py...

journal_title：Gut

authors： Morris A,Nicholson G,Zwi J,Vanderwee M

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Transforming growth factor beta (TGF-beta) is frequently involved in gastrointestinal carcinogenesis although its contribution to oesophageal adenocarcinoma (AC) and its precursor Barrett's oesophageal epithelium (BE) metaplasia are unclear. METHODS:Expression of TGF-beta signalling components was ...

journal_title：Gut

authors： Onwuegbusi BA,Aitchison A,Chin SF,Kranjac T,Mills I,Huang Y,Lao-Sirieix P,Caldas C,Fitzgerald RC

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Although peroxisome proliferator activated receptor gamma (PPARgamma) agonists have been implicated in differentiation and growth inhibition of cancer cells, the potential therapeutic and chemopreventive effects on gastric cancer are poorly defined. We examined the in vitro and in vivo effects of PP...

journal_title：Gut

authors： Leung WK,Bai AH,Chan VY,Yu J,Chan MW,To KF,Wu JR,Chan KK,Fu YG,Chan FK,Sung JJ

更新日期：2004-03-01 00:00:00

abstract：:Lymphocytic gastritis and primary gastric lymphoma are rare conditions with unknown aetiology. It has recently been suggested that Helicobacter pylori has a role in the pathogenesis of both of them. The occurrence of lymphocytic gastritis and H pylori was studied in a series of patients with primary gastric lymphoma. ...

journal_title：Gut

authors： Miettinen A,Karttunen TJ,Alavaikko M

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:The risk of colorectal cancer after a previous negative colonoscopy is very low. Nevertheless, interval cancers occur. We aimed to assess the characteristics and predictors of interval cancers after negative colonoscopy. METHODS:A population-based case-control study was conducted in Southern Germany in 2003-...

journal_title：Gut

authors： Brenner H,Chang-Claude J,Seiler CM,Hoffmeister M

更新日期：2012-11-01 00:00:00

abstract：:Probiotic administration may exert a protective effect in colitis by preventing mucosal barrier disruption and influencing the extent of mucosal injury. ...

journal_title：Gut

authors： Gionchetti P,Lammers KM,Rizzello F,Campieri M

更新日期：2005-07-01 00:00:00

abstract：:Cimetidine 200 mg three times daily and 400 mg at night was given to 10 subjects for four weeks. Apparent liver blood flow was measured by indocyanine green clearance and microsomal enzyme activity by antipyrine clearance, before and after cimetidine. There was no reduction in indocyanine green clearance but antipyrin...

journal_title：Gut

authors： Daneshmend TK,Ene MD,Parker G,Roberts CJ

更新日期：1984-02-01 00:00:00

abstract：:Patients with Crohn's disease commonly develop ileal and less commonly colonic strictures, containing various degrees of inflammation and fibrosis. While predominantly inflammatory strictures may benefit from a medical anti-inflammatory treatment, predominantly fibrotic strictures currently require endoscopic balloon ...

journal_title：Gut

authors： Bettenworth D,Bokemeyer A,Baker M,Mao R,Parker CE,Nguyen T,Ma C,Panés J,Rimola J,Fletcher JG,Jairath V,Feagan BG,Rieder F,Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium.

更新日期：2019-06-01 00:00:00

abstract：:We previously noted a region of amino acid sequence homology between A-gliadin, a major alpha-gliadin component known to activate coeliac disease, and the early region E1b protein of human adenovirus serotype 12 (Ad12), an adenovirus isolated from the human intestinal tract. In the present study sera from coeliac dise...

journal_title：Gut

authors： Kagnoff MF,Paterson YJ,Kumar PJ,Kasarda DD,Carbone FR,Unsworth DJ,Austin RK

更新日期：1987-08-01 00:00:00

abstract：:The aims of the present study were to determine the relative amplitudes of intragastric motor responses evoked by different vagal branches and to establish whether the effects of acute or chronic vagotomy could be predicted from these data. Intragastric pressure responses to electrical stimulation of the vagus were me...

journal_title：Gut

authors： Andrews PL,Lawes IN,Bower AJ

更新日期：1980-10-01 00:00:00