Extramedullary haemopoiesis in the small bowel.

Abstract:

:A patient with myelofibrosis developed repeated gastrointestinal haemorrhage from the small intestine, which was found to be infiltrated with extramedullary haemopoiesis. Nineteen months later he presented with subacute intestinal obstruction; radiology and laparotomy documented progressive infiltration of the small bowel. Histological examination of the resected terminal ileum showed patchy mucosal ulceration, with underlying submucosal and serosal extramedullary haemopoiesis.

journal_name

Gut

journal_title

Gut

authors

Sharma BK,Pounder RE,Cruse JP,Knowles SM,Lewis AA

doi

10.1136/gut.27.7.873

subject

Has Abstract

pub_date

1986-07-01 00:00:00

pages

873-5

issue

7

eissn

0017-5749

issn

1468-3288

journal_volume

27

pub_type

杂志文章

相关文献

GUT文献大全
  • Jejunal bacterial overgrowth and intestinal permeability in children with immunodeficiency syndromes.

    abstract::Seventeen paediatric patients with immunodeficiency syndromes (10 with selective IgA deficiency, four with panhypogammaglobulinaemia, and three with selective T cell deficiency) were investigated for bacterial overgrowth of the small intestine and gut permeability to macromolecules. Five of 12 patients showed viable b...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.31.8.879

    authors: Pignata C,Budillon G,Monaco G,Nani E,Cuomo R,Parrilli G,Ciccimarra F

    更新日期:1990-08-01 00:00:00

  • Chronic painless pancreatitis.

    abstract::This paper describes four patients whose chief symptoms were steatorrhoea and loss of weight. Despite the absence of a history of abdominal pain investigations showed that these patients had chronic pancreatitis, which responded to medical treatment. The pathological findings in two of these cases and in six which cam...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.3.3.252

    authors: GOULSTON SJ,GALLAGHER ND

    更新日期:1962-09-01 00:00:00

  • Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.

    abstract:OBJECTIVE:Pancreatic acinar cell maturation is dependent on the activity of the pancreas transcription factor 1 (PTF1) complex. Induction of pancreatitis leads to MAP kinase activation and transient suppression of the acinar differentiation programme. We investigated the role of MAP kinase-interacting kinase 1 (Mnk1) i...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2013-306068

    authors: Cendrowski J,Lobo VJ,Sendler M,Salas A,Kühn JP,Molero X,Fukunaga R,Mayerle J,Lerch MM,Real FX

    更新日期:2015-06-01 00:00:00

  • Portal and systemic haemodynamic action of N-acetylcysteine in patients with stable cirrhosis.

    abstract::The effects of intravenous N-acetylcysteine on hepatic and systemic haemodynamics were investigated in 11 patients with stable cirrhosis (eight alcohol; two primary biliary cirrhosis; one cryptogenic). N-acetylcysteine administration had no effect on the mean heart rate or mean arterial blood pressure despite a signif...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.35.9.1290

    authors: Jones AL,Bangash IH,Bouchier IA,Hayes PC

    更新日期:1994-09-01 00:00:00

  • An investigation into the reversibility of the morphological and cytokinetic changes seen in the small intestine of riboflavin deficient rats.

    abstract:BACKGROUND:Impaired iron handling in riboflavin deficiency is thought to be partially a result of significant morphological and cytokinetic changes within the small intestine. AIMS:The aim of the study was to find out if the responses of the rat small intestine to riboflavin deficiency induced at weaning could be reve...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.39.2.220

    authors: Williams EA,Rumsey RD,Powers HJ

    更新日期:1996-08-01 00:00:00

  • Lymphocyte subpopulations in adult coeliac disease.

    abstract::Rosetting techniques were used to estimate T and B cell subpopulations in the peripheral blood in patients with treated and untreated adult coeliac disease and in control subjects. In patients with untreated coeliac disease, T cell numbers were significantly lower than in controls or treated patients, although there w...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.19.10.892

    authors: Bullen AW,Losowsky MS

    更新日期:1978-10-01 00:00:00

  • Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology.

    abstract::A multidisciplinary panel of 18 physicians and 3 non-physicians from eight countries (Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the literature on diagnosis and management of adult coeliac disease (CD). This paper presents the recommendations of the British Society of Gastroenterolo...

    journal_title:Gut

    pub_type: 杂志文章,实务指引

    doi:10.1136/gutjnl-2013-306578

    authors: Ludvigsson JF,Bai JC,Biagi F,Card TR,Ciacci C,Ciclitira PJ,Green PH,Hadjivassiliou M,Holdoway A,van Heel DA,Kaukinen K,Leffler DA,Leonard JN,Lundin KE,McGough N,Davidson M,Murray JA,Swift GL,Walker MM,Zingone F,Sa

    更新日期:2014-08-01 00:00:00

  • Bone marrow transplantation improves hepatic fibrosis in Abcb4-/- mice via Th1 response and matrix metalloproteinase activity.

    abstract:OBJECTIVE:Reports on the effects of bone marrow-derived cells on hepatic fibrosis are contradictory. Impaired fibrosis but increased inflammation has recently been demonstrated 10 weeks after bone marrow transplantation (BM-Tx) in Abcb4-/- mice. It is hypothesised that BM-Tx might have long-term therapeutic potential b...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2011-300608

    authors: Roderfeld M,Rath T,Pasupuleti S,Zimmermann M,Neumann C,Churin Y,Dierkes C,Voswinckel R,Barth PJ,Zahner D,Graf J,Roeb E

    更新日期:2012-06-01 00:00:00

  • Multiple balloon-like lesions in the small intestine of an adult with chronic diarrhoea.

    abstract:CLINICAL PRESENTATION:A 28-year-old woman presented with a 3-year history of chronic watery diarrhoea along with abdominal pain and bloating, which could mostly be alleviated after defecation. Her symptom of diarrhoea, at least three times a day, could be relieved by neither probiotics nor antidiarrhoeal agents. She ha...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2018-316182

    authors: Zhou CB,Lu H,Chen YX,Fang JY

    更新日期:2019-03-01 00:00:00

  • Cholic acid synthesis as an index of the severity of liver disease in man.

    abstract::Bile acid pool size and kinetics were determined in 17 patients with cirrhosis and 11 patients without liver disease and correlated with the severity of liver disease as determined by the usual clinical and laboratory criteria. In order to assess the severity of liver disease, a grading system was devised which assign...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.14.11.895

    authors: McCormick WC 3rd,Bell CC Jr,Swell L,Vlahcevic ZR

    更新日期:1973-11-01 00:00:00

  • Drug metabolism in hepatosplenic schistosomiasis in the Sudan: a study with antipyrine.

    abstract::The disposition of antipyrine following oral administration of 1200 mg has been investigated in 10 patients with histologically confirmed hepatosplenic schistosomiasis and 11 normal subjects living in Sudan. Drug metabolising activity as assessed by antipyrine clearance was similar in patients when compared with norma...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.19.9.808

    authors: Homeida M,Salih SY,Branch RA

    更新日期:1978-09-01 00:00:00

  • Controlled randomised trial of visual biofeedback versus muscle training without a visual display for intractable constipation.

    abstract::Training to contract the abdominal muscles effectively and to relax the pelvic floor during defecation straining helps some patients with severe constipation. Hitherto all such training has used a visible or audible signal of sphincter muscle activity as a biofeedback method to assist in relaxation. A randomised contr...

    journal_title:Gut

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/gut.37.1.95

    authors: Koutsomanis D,Lennard-Jones JE,Roy AJ,Kamm MA

    更新日期:1995-07-01 00:00:00

  • Duodenal adenomatosis in familial adenomatous polyposis.

    abstract:BACKGROUND:The prevalence of duodenal carcinoma is much higher in familial adenomatous polyposis (FAP) than in the background population, and duodenal adenomatosis is found in most polyposis patients. AIMS:To describe the long term natural history of duodenal adenomatosis in FAP and evaluate if cancer prophylactic sur...

    journal_title:Gut

    pub_type: 杂志文章,多中心研究

    doi:10.1136/gut.2003.027771

    authors: Bülow S,Björk J,Christensen IJ,Fausa O,Järvinen H,Moesgaard F,Vasen HF,DAF Study Group.

    更新日期:2004-03-01 00:00:00

  • JAK selectivity for inflammatory bowel disease treatment: does it clinically matter?

    abstract::The two major forms of inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), are chronic immune-mediated conditions characterised by an increased production of pro-inflammatory cytokines that act as critical drivers of intestinal inflammation. Anti-cytokine therapy has been s...

    journal_title:Gut

    pub_type: 杂志文章,评审

    doi:10.1136/gutjnl-2019-318448

    authors: Danese S,Argollo M,Le Berre C,Peyrin-Biroulet L

    更新日期:2019-10-01 00:00:00

  • Composition of gastro-oesophageal refluxate.

    abstract::Fifty two patients with abnormal acid gastro-oesophageal reflux were studied by simultaneous oesophageal pH monitoring and continuous aspiration for 16 hours. Aspirates (from discrete two hour periods) were analysed for volume, pH, bile acids (conjugated and unconjugated), trypsin, and pepsin. The results were compare...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.32.10.1093

    authors: Gotley DC,Morgan AP,Ball D,Owen RW,Cooper MJ

    更新日期:1991-10-01 00:00:00

  • Cryptosporidium, chronic diarrhoea and the proximal small intestinal mucosa.

    abstract::The association between Cryptosporidium, chronic diarrhoea and a proximal small intestinal mucosal enteropathy was reviewed over a six and a half year period. One hundred and twenty three children with cryptosporidiosis and no clinical evidence of immune deficiency were identified. 50% of children excreting only Crypt...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.33.8.1057

    authors: Phillips AD,Thomas AG,Walker-Smith JA

    更新日期:1992-08-01 00:00:00

  • Metabolism of 125I-labelled trypsin in man: evidence of recirculation.

    abstract::125I-labelled human trypsin metabolism has been investigated in man. Three subjects received 125I-trypsin and 131I-albumin intravenously. Against a background secretin infusion (1 U/kg/h), trypsin decayed biexponentially from the serum with half-lives of 17.5, 21, and 24 minutes for the rapid disappearance phase and 5...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.21.7.580

    authors: Lake-Bakaar G,Rubio CE,McKavanagh S,Potter BJ,Summerfield JA

    更新日期:1980-07-01 00:00:00

  • Dermatogenic enteropathy.

    abstract::Steatorrhoea has been found in a large proportion of patients with inflammatory dermatoses, especially eczema and psoriasis. It is due to the rash itself and disappears rapidly after topical treatment of the skin. This particular enteropathy, unlike that associated with dermatitis herpetiformis, is not accompanied by ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.11.4.292

    authors: Marks J,Shuster S

    更新日期:1970-04-01 00:00:00

  • Increased concanavalin A induced suppression in treated and untreated coeliac disease.

    abstract::The generation of suppression by concanavalin A in peripheral blood mononuclear cells in treated and untreated coeliac subjects using an in vitro assay was found to be significantly increased when compared with controls. The response of peripheral blood mononuclear cells to the plant mitogen concanavalin A (con A) was...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.25.6.644

    authors: O'Farrelly C,McKeever U,Feighery C,Weir DG

    更新日期:1984-06-01 00:00:00

  • Granulomatous arthritis in Crohn's disease.

    abstract::A case is described of non-necrotizing, epithelioid cell granulomatous synovitis of the ankle of a 22-year-old man with Crohn's disease. It appears to be the first published example of granulomatous arthritis in association with Crohn's disease. ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.13.4.257

    authors: Lindström C,Wramsby H,Ostberg G

    更新日期:1972-04-01 00:00:00

  • Diagnostic misclassification reduces the ability to detect linkage in inflammatory bowel disease genetic studies.

    abstract:BACKGROUND:Linkage data have now identified several inflammatory bowel disease (IBD) susceptibility loci but these data have not been consistently replicated in independent studies. One potential explanation for this is the possibility that patients enrolled in such studies may have been erroneously classified with res...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.49.6.773

    authors: Silverberg MS,Daly MJ,Moskovitz DN,Rioux JD,McLeod RS,Cohen Z,Greenberg GR,Hudson TJ,Siminovitch KA,Steinhart AH

    更新日期:2001-12-01 00:00:00

  • Nerve activity recordings in routine human intestinal biopsies.

    abstract:BACKGROUND:Most direct understanding of enteric nerve (patho)physiology has been obtained by electrode and imaging techniques in animal models and human surgical samples. Until now, neuronal activity recordings from a more accessible human tissue source have remained a true challenge. OBJECTIVES:To record nerve activi...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2011-301777

    authors: Cirillo C,Tack J,Vanden Berghe P

    更新日期:2013-02-01 00:00:00

  • Behaviour of acid secretion, gastrin release, serum pepsinogen I, and gastric emptying of liquids over six months from eradication of helicobacter pylori in duodenal ulcer patients. A controlled study.

    abstract::The behaviour of basal and stimulated acid secretion, gastrin release, serum pepsinogen I, and gastric emptying of liquids was studied in 19 consecutive patients with Helicobacter pylori positive duodenal ulcer, over a follow up period of six months. Eleven patients were studied before and at three and six months afte...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.37.2.210

    authors: Parente F,Maconi G,Sangaletti O,Minguzzi M,Vago L,Bianchi Porro G

    更新日期:1995-08-01 00:00:00

  • The effects of different bile salts on the absorption of fluid, electrolytes, and monosaccharides in the small intestine of the rat in vivo.

    abstract::The effects of different bile salts on the absorption of fluid, electrolytes, and monosaccharides have been investigated in the rat small intestine in vivo. In the jejunum, deoxycholate (1 mM) impaired absorption of water and potassium, but not of sodium or glucose; at higher concentrations (2.5 and 5 mM) secretion of...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.13.8.596

    authors: Harries JT,Sladen GE

    更新日期:1972-08-01 00:00:00

  • Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome.

    abstract:BACKGROUND AND AIMS:Teduglutide, a GLP-2 analogue, may restore intestinal structural and functional integrity by promoting repair and growth of the mucosa and reducing gastric emptying and secretion, thereby increasing fluid and nutrient absorption in patients with short bowel syndrome (SBS). This 24-week placebo-contr...

    journal_title:Gut

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1136/gut.2010.218271

    authors: Jeppesen PB,Gilroy R,Pertkiewicz M,Allard JP,Messing B,O'Keefe SJ

    更新日期:2011-07-01 00:00:00

  • TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.

    abstract:BACKGROUND AND OBJECTIVE:Progression of a colorectal adenoma to invasive cancer occurs in a minority of adenomas and is the most crucial step in colorectal cancer pathogenesis. In the majority of cases, this is associated with gain of a substantial part of chromosome 20q, indicating that multiple genes on the 20q ampli...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2011-301153

    authors: Sillars-Hardebol AH,Carvalho B,Tijssen M,Beliën JA,de Wit M,Delis-van Diemen PM,Pontén F,van de Wiel MA,Fijneman RJ,Meijer GA

    更新日期:2012-11-01 00:00:00

  • Escherichia coli strains colonising the gastrointestinal tract protect germfree mice against Salmonella typhimurium infection.

    abstract:BACKGROUND:Escherichia coli is part of the normal gastrointestinal microflora which exerts a barrier effect against enteropathogens. Several E coli strains develop a protective effect against other Enterobacteriaceae. AIMS:Two E coli strains, EM0, a human faecal strain, and JM105 K-12 were tested for their ability to ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.49.1.47

    authors: Hudault S,Guignot J,Servin AL

    更新日期:2001-07-01 00:00:00

  • U.K. guidelines on the management of variceal haemorrhage in cirrhotic patients.

    abstract::These updated guidelines on the management of variceal haemorrhage have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines which this document supersedes were written in 2...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2015-309262

    authors: Tripathi D,Stanley AJ,Hayes PC,Patch D,Millson C,Mehrzad H,Austin A,Ferguson JW,Olliff SP,Hudson M,Christie JM,Clinical Services and Standards Committee of the British Society of Gastroenterology.

    更新日期:2015-11-01 00:00:00

  • Further characterisation of the 'ileal brake' reflex in man--effect of ileal infusion of partial digests of fat, protein, and starch on jejunal motility and release of neurotensin, enteroglucagon, and peptide YY.

    abstract::Previous studies have shown that ileal infusion of partially digested triglyceride inhibits jejunal motility. The partial digest used in those studies contained a mixture of glycerol, free fatty acid, mono-, di-, and triglycerides. In Part I of the present study we have separately infused emulsions containing either g...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.29.8.1042

    authors: Spiller RC,Trotman IF,Adrian TE,Bloom SR,Misiewicz JJ,Silk DB

    更新日期:1988-08-01 00:00:00

  • MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis.

    abstract:BACKGROUND:MicroRNAs (miRNAs) are important in hepatic pathophysiology and the development of liver cancer. OBJECTIVE:To explore miRNAs that are regulated with the progression of liver fibrosis caused by chronic liver disease. DESIGN:The regulated miRNAs in human livers infected with hepatitis C virus were identified...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2011-300717

    authors: Ogawa T,Enomoto M,Fujii H,Sekiya Y,Yoshizato K,Ikeda K,Kawada N

    更新日期:2012-11-01 00:00:00