Abstract:
:Bran, ispaghula (Fybogel), and lactulose were given to three groups of patients with diverticular disease for four weeks. Faecal weights, bile acids, fat and electrolytes, transit time, and colonic motility were estimated before and after treatment. Stool weight increased, notably with Fybogel. Cereal bran had the greatest effect on the transit time, reducing it significantly. There were no changes in faecal bile acids, fat or electrolytes. Coarse bran reduced colonic motility and the number of high pressure waves after food; Fybogel increased the basal pressure and was without effect on the food-stimulated pressures; whereas lactulose influenced neither. All agents paradoxically equally alleviated symptoms.
journal_name
Gutjournal_title
Gutauthors
Eastwood MA,Smith AN,Brydon WG,Pritchard Jdoi
10.1136/gut.19.12.1144subject
Has Abstractpub_date
1978-12-01 00:00:00pages
1144-7issue
12eissn
0017-5749issn
1468-3288journal_volume
19pub_type
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