Development of chronic hepatocerebral degeneration eight years after a distal splenorenal (Warren) shunt.

abstract：:The motility of the descending colon was studied in nine patients before and after resection of the rectum for cancer. This operation parasympathectomises and generally also sympathectomises the remaining left colon. Motor activity was significantly reduced by sleep before and after surgery. There was also a reduction...

journal_title：Gut

authors： Catchpole BN

更新日期：1988-05-01 00:00:00

abstract：:Iron deficiency anaemia is one of the most common disorders in the world. Also, one third of inflammatory bowel disease (IBD) patients suffer from recurrent anaemia. Anaemia has significant impact on the quality of life of affected patients. Chronic fatigue, a frequent IBD symptom itself, is commonly caused by anaemia...

journal_title：Gut

authors： Gasche C,Lomer MC,Cavill I,Weiss G

更新日期：2004-08-01 00:00:00

abstract：:The leakiness of the cell membranes of colonic epithelial cells isolated by the collagenase/Dispase technique from normal or diseased colons was assessed in a 4 h 51Cr release assay. Cells from normal, adenoma bearing or cancer bearing colons showed 51Cr release of 8% or less in almost all of 46 cell populations teste...

journal_title：Gut

authors： Gibson PR,van de Pol E,Barratt PJ,Doe WF

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Integrins mediate cell matrix adhesion and regulate cell growth and survival. In colonic epithelial cells, alpha(2)beta(1) integrin controls glandular differentiation and proliferation. Butyrate stimulates differentiation and induces apoptosis in vitro. AIMS:We investigated whether butyrate induction of apo...

journal_title：Gut

authors： Buda A,Qualtrough D,Jepson MA,Martines D,Paraskeva C,Pignatelli M

更新日期：2003-05-01 00:00:00

abstract：:Patients with the Peutz-Jeghers syndrome carry a slight, though definite, increased risk of gastrointestinal carcinoma. The malignant potentiality of Peutz-Jeghers hamartomatous polyps, generally considered benign, is supported by this report. Two cases of metastasising gastrointestinal carcinoma associated with the P...

journal_title：Gut

authors： Cochet B,Carrel J,Desbaillets L,Widgren S

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Polyamines are essential for cell growth. Dietary and probably gut bacterial derived polyamines contribute significantly to the polyamine body pool. AIMS:To evaluate the influence of dietary, luminal polyamines on growth and development of different gastrointestinal organs in normally growing rats. METHODS...

journal_title：Gut

authors： Löser C,Eisel A,Harms D,Fölsch UR

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Although evidence points to a role for histamine and serotonin in visceral hypersensitivity, activation of calcium channels such as transient receptor potential vanilloid 4 (TRPV4) also causes visceral hypersensitivity. We hypothesised that TRPV4 is important for the generation of hypersensitivity, mediating...

journal_title：Gut

authors： Cenac N,Altier C,Motta JP,d'Aldebert E,Galeano S,Zamponi GW,Vergnolle N

更新日期：2010-04-01 00:00:00

abstract：:The prevalence of methane production in an adult population of 256 subjects was 41%, but it was significantly higher in females (49%), than males (33%). When the population was subdivided into ethnic groups. Caucasians (48%) and Black (45%) had significantly more methane producers than Orientals (24%) and Indians (32%...

journal_title：Gut

authors： Pitt P,de Bruijn KM,Beeching MF,Goldberg E,Blendis LM

更新日期：1980-11-01 00:00:00

abstract：:Peak plasma levels were reduced after an oral dose of 40 mg prednisolone in six patients with severe acute colitis as compared with six normal subjects, though total absorption appeared to be similar; the findings suggest that prednisolone absorption was delayed in acute colitis. A dilutional fall in plasma albumin wa...

journal_title：Gut

authors： Elliott PR,Powell-Tuck J,Gillespie PE,Laidlow JM,Lennard-Jones JE,English J,Chakraborty J,Marks V

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:Osteoporosis and fractures are frequently encountered in patients with Crohn's disease. In order to prevent fractures, treatment with bone protecting drugs appears warranted early in the course of bone disease when bone loss is not yet prominent. We therefore aimed to demonstrate a beneficial effect on bone d...

journal_title：Gut

authors： van Bodegraven AA,Bravenboer N,Witte BI,Dijkstra G,van der Woude CJ,Stokkers PC,Russel MG,Oldenburg B,Pierik M,Roos JC,van Hogezand RA,Dik VK,Oostlander AE,Netelenbos JC,van de Langerijt L,Hommes DW,Lips P,Dutch Initiat

更新日期：2014-09-01 00:00:00

abstract：:In 18 patients intermediary anabolic metabolites of 5-FU were measured in normal colonic mucosa and colorectal cancer tissue of intravenous bolus injection or continuous infusion. Higher total concentrations of 5-FU products were found in the cancers when compared with normal colonic tissue. There appeared to be no ev...

journal_title：Gut

authors： Giles GR,Woodhouse L,Finan PJ,Chisholm EM

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND AND AIMS:To compare extracorporeal shock wave lithotripsy (ESWL) and laser induced shock wave lithotripsy (LISL) of retained bile duct stones to stone free rate, number of therapeutic sessions, and costs. PATIENTS:Thirty four patients were randomly assigned to either ESWL or LISL therapy. The main reasons f...

journal_title：Gut

authors： Jakobs R,Adamek HE,Maier M,Krömer M,Benz C,Martin WR,Riemann JF

更新日期：1997-05-01 00:00:00

abstract：:Faecal bile acid excretion was examined in 13 patients with adenomatous polyps of the large bowel and compared with a series of matched healthy subjects. Bile acids were analysed in detail with respect to the composition of individual bile acids and their mode of conjugation. The total excretion of bile acids by the p...

journal_title：Gut

authors： Tanida N,Hikasa Y,Shimoyama T,Setchell KD

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary lipid absorption by the gall bladder mucosa and the cholesterol content of the gall bladder wall appear to play a role in cholesterol gall stone formation. As the scavenger receptor class B type I (SR- BI) regulates cellular cholesterol uptake, we studied its expression in human and murine g...

journal_title：Gut

authors： Miquel JF,Moreno M,Amigo L,Molina H,Mardones P,Wistuba II,Rigotti A

更新日期：2003-07-01 00:00:00

abstract：:Previous studies have suggested that profound inhibition of gastric acid secretion may increase exposure to potentially carcinogenic N-nitroso compounds. The aim of this study was to find out if the proton pump inhibitor omeprazole (20 mg daily) is associated with increased concentrations of potentially carcinogenic N...

journal_title：Gut

authors： Verdu E,Viani F,Armstrong D,Fraser R,Siegrist HH,Pignatelli B,Idström JP,Cederberg C,Blum AL,Fried M

更新日期：1994-04-01 00:00:00

abstract：:Fasting serum gastrin has been measured by radioimmunoassay in 72 patients with duodenal ulcer and compared with that in normals, patients with gastric ulcer, and with the Zollinger-Ellison syndrome. The mean (+/- SEM) gastrin levels were 15.7 +/- 1.5 pg/ml in the duodenal ulcer group, 32.1 +/- 4.3 pg/ml in normals, 1...

journal_title：Gut

authors： Korman MG,Soveny C,Hansky J

更新日期：1971-11-01 00:00:00

abstract：:Evidence for the occurrence of microbial breakdown of carbohydrate in the human colon has been sought by measuring short chain fatty acid (SCFA) concentrations in the contents of all regions of the large intestine and in portal, hepatic and peripheral venous blood obtained at autopsy of sudden death victims within fou...

journal_title：Gut

authors： Cummings JH,Pomare EW,Branch WJ,Naylor CP,Macfarlane GT

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:The risk of colorectal cancer after a previous negative colonoscopy is very low. Nevertheless, interval cancers occur. We aimed to assess the characteristics and predictors of interval cancers after negative colonoscopy. METHODS:A population-based case-control study was conducted in Southern Germany in 2003-...

journal_title：Gut

authors： Brenner H,Chang-Claude J,Seiler CM,Hoffmeister M

更新日期：2012-11-01 00:00:00

abstract：:It has been reported that intestinal permeability to polyethylene glycol 400 is increased in patients with Crohn's disease and their apparently unaffected first degree relatives. Because of the implications that these findings have for the aetiology of Crohn's disease these studies were repeated. Patients with Crohn's...

journal_title：Gut

authors： Teahon K,Smethurst P,Levi AJ,Menzies IS,Bjarnason I

更新日期：1992-03-01 00:00:00

abstract：:The value of the bipolar electrocoagulator in the haemostasis of bleeding ulcers is controversial. We have therefore investigated the effect of different coagulation times on vessel weld strength achieved by the bipolar device. Welds were then made in vessels of known diameter using a standard 10F endoscopic haemostat...

journal_title：Gut

authors： Harrison JD,Morris DL

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Standard triple therapies are the most used treatment in clinical practice. However, a critical fall in the H pylori eradication rate following these therapies has been observed in the last few years. The sequential regimen is a novel, promising therapeutic approach. OBJECTIVES:To evaluate the available dat...

journal_title：Gut

authors： Zullo A,De Francesco V,Hassan C,Morini S,Vaira D

更新日期：2007-10-01 00:00:00

abstract：:mu-, delta- and kappa-opioid receptors are widely expressed in the central nervous system where they mediate the strong analgesic and mood-altering actions of opioids, and modulate numerous endogenous functions. To investigate the contribution of the kappa-opioid receptor (KOR) to opioid function in vivo, we have gene...

journal_title：Gut

authors： Black D,Trevethick M

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside from changes in genetic background and diet, could sign different...

journal_title：Gut

authors： Serino M,Luche E,Gres S,Baylac A,Bergé M,Cenac C,Waget A,Klopp P,Iacovoni J,Klopp C,Mariette J,Bouchez O,Lluch J,Ouarné F,Monsan P,Valet P,Roques C,Amar J,Bouloumié A,Théodorou V,Burcelin R

更新日期：2012-04-01 00:00:00

abstract：:Thirty-two patients with diarrhoea, on average four years following truncal vagotomy and drainage, were studied. A comparison was made with 24 patients without postvagotomy diarrhoea. The incidence of bacterial colonization of the upper small intestine was no different in the two groups, though patients with a gastroe...

journal_title：Gut

authors： Browning GG,Buchan KA,Mackay C

更新日期：1974-08-01 00:00:00

abstract：:The staining of HLA class II antigens, the presence of cells positive for interleukin-2 receptors, the proportion of crypt cells in mitosis in the jejunal biopsy specimens, and the dose of coeliac disease marker HLA-DQ genes were studied in 75 healthy family members of coeliac disease patients. Eleven had silent coeli...

journal_title：Gut

authors： Holm K,Savilahti E,Koskimies S,Lipsanen V,Mäki M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The molecular mechanisms mediating the antiproliferative effects of interferon alpha on human pancreatic carcinoma cells are poorly understood. AIM:To characterise the effects of interferon alpha on protein kinase C isoenzyme expression in interferon alpha sensitive and resistant human pancreatic tumour cel...

journal_title：Gut

authors： Rosewicz S,Weder M,Kaiser A,Riecken EO

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:Current strategies to guide selection of neoadjuvant therapy in oesophageal adenocarcinoma (OAC) are inadequate. We assessed the ability of a DNA damage immune response (DDIR) assay to predict response following neoadjuvant chemotherapy in OAC. DESIGN:Transcriptional profiling of 273 formalin-fixed paraffin-...

journal_title：Gut

authors： Turkington RC,Knight LA,Blayney JK,Secrier M,Douglas R,Parkes EE,Sutton EK,Stevenson L,McManus D,Halliday S,McCavigan AM,Logan GE,Walker SM,Steele CJ,Perner J,Bornschein J,MacRae S,Miremadi A,McCarron E,McQuaid S,

更新日期：2019-11-01 00:00:00

abstract：:Cell cultures derived from Crohn's disease and control tissues were subjected to a series of tests designed to detect persistent, non-cytocidal virus infection. No evidence for any such infection was found, and it is concluded that persistent viral infection of gut tissues is unlikely to play a significant role in the...

journal_title：Gut

authors： Phillpotts RJ,Hermon-Taylor J,Teich NM,Brooke BN

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The incidence of oesophageal adenocarcinoma (OAC) has been increasing rapidly with a dismal survival rate of less than 20%. Understanding the genomic aberrations and biology of this cancer may enhance disease interventions. This study aimed to use genome-wide genomic and expression data to enhance t...

journal_title：Gut

authors： Goh XY,Rees JR,Paterson AL,Chin SF,Marioni JC,Save V,O'Donovan M,Eijk PP,Alderson D,Ylstra B,Caldas C,Fitzgerald RC

更新日期：2011-10-01 00:00:00

abstract：:Bowel function was assessed in 51 subjects: 10 women and seven men who habitually consumed an omnivorous, vegetarian, or vegan diet. The subjects on these diets had a mean intake of fibre of 23 g, 37 g, and 47 g respectively. Mean transit times were variable and not significantly different between the groups. Vegans, ...

journal_title：Gut

authors： Davies GJ,Crowder M,Reid B,Dickerson JW

更新日期：1986-02-01 00:00:00