Acid, motility, and ulcers: a comparison of cisapride with placebo in the prevention of duodenal ulcer relapse.

abstract：:Some patients with diarrhoea predominant irritable bowel syndrome have increased rectal sensitivity. It is uncertain, however, whether the diarrhoea is a consequence of the rectal sensitivity or if it is sensitising the rectum in some way. The aim of this study was to assess whether inducing diarrhoea in normal health...

journal_title：Gut

authors： Houghton LA,Wych J,Whorwell PJ

更新日期：1995-08-01 00:00:00

abstract：:Lymphocytic gastritis and primary gastric lymphoma are rare conditions with unknown aetiology. It has recently been suggested that Helicobacter pylori has a role in the pathogenesis of both of them. The occurrence of lymphocytic gastritis and H pylori was studied in a series of patients with primary gastric lymphoma. ...

journal_title：Gut

authors： Miettinen A,Karttunen TJ,Alavaikko M

更新日期：1995-10-01 00:00:00

abstract：AIM:This prospective study aimed to compare the accuracy of echo enhanced ultrasound with spiral computed tomography (CT) in assessing acute pancreatitis and to explore the correlation between ultrasound findings and clinical outcome. METHODS:Thirty one patients (24 men and 7 women, median age 39 years, range 19-67 ye...

journal_title：Gut

authors： Rickes S,Uhle C,Kahl S,Kolfenbach S,Monkemuller K,Effenberger O,Malfertheiner P

更新日期：2006-01-01 00:00:00

abstract：:The effects of drugs which change the bile-salt-independent fraction of bile flow on Na(+)K(a+) and Mg(2+) activated ATPases were studied in membrane fractions rich in bile canaliculi. The administration of phenobarbital caused no induction of these enzymes which could explain the increased bile flow observed in the r...

journal_title：Gut

authors： Laperche Y,Launay A,Oudéa P

更新日期：1972-11-01 00:00:00

abstract：BACKGROUND:5-Lipoxygenase products play a part in inflammatory response. AIMS:The effect of intracolonic administration of zileuton (a 5-lipoxygenase inhibitor) on colonic damage and eicosanoid local release was assessed in a rat model of colitis. METHODS:Ninety rats with trinitrobenzenesulphonic acid induced colitis...

journal_title：Gut

authors： Bertrán X,Mañé J,Fernández-Bañares F,Castellá E,Bartolí R,Ojanguren I,Esteve M,Gassull MA

更新日期：1996-06-01 00:00:00

abstract：:The effect of increasing the calcium, magnesium and sodium concentration in gall bladder bile samples from 21 patients with gall stones and nine controls on the in vitro rate of formation of cholesterol microcrystals and numbers of cholesterol microcrystals formed was examined. Addition of these cations to raise the m...

journal_title：Gut

authors： Neithercut WD

更新日期：1989-05-01 00:00:00

abstract：:Paracetamol poisoning is the most common cause of fulminant liver failure in the United Kingdom. An accurate assessment of prognosis at the time of referral will allow the appropriate application of liver transplantation in this setting. The outcome of 92 patients consecutively admitted to a specialist liver unit with...

journal_title：Gut

authors： Mutimer DJ,Ayres RC,Neuberger JM,Davies MH,Holguin J,Buckels JA,Mayer AD,McMaster P,Elias E

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:In liver regeneration after portal branch ligation we previously showed that early cellular changes are observed in both the proliferating and atrophying liver lobes. They are therefore not indicative of future proliferative response. In this study we attempted to define precisely, in the same model, the tim...

journal_title：Gut

authors： Stärkel P,Lambotte L,Sempoux C,De Saeger C,Saliez A,Maiter D,Horsmans Y

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Transforming growth factor beta (TGF-beta) is frequently involved in gastrointestinal carcinogenesis although its contribution to oesophageal adenocarcinoma (AC) and its precursor Barrett's oesophageal epithelium (BE) metaplasia are unclear. METHODS:Expression of TGF-beta signalling components was ...

journal_title：Gut

authors： Onwuegbusi BA,Aitchison A,Chin SF,Kranjac T,Mills I,Huang Y,Lao-Sirieix P,Caldas C,Fitzgerald RC

更新日期：2006-06-01 00:00:00

abstract：:Based on a diary which was kept while preparing for and undergoing pan-proctocolectomy, the paper describes the process of coming to terms with an ileostomy. A number of stages in the process are identified: anticipation, reorientation, trauma, maintenance of selfimage and accommodation. The social-psychological strat...

journal_title：Gut

authors： Kelly MP

更新日期：1987-01-01 00:00:00

abstract：:To evaluate the effects of cisapride on gastric emptying of extracellular fat and hunger and fullness 10 volunteers consumed a meal consisting of 60 ml technectium-99m (99mTc)-V-thiocyanate labelled olive oil and 290 ml indium-113m (113mIn) labelled soup after taking cisapride (10 mg four times daily orally) and place...

journal_title：Gut

authors： Jones KL,Horowitz M,Carney BI,Sun WM,Chatterton BE

更新日期：1996-03-01 00:00:00

abstract：:A clinical, biochemical, and pathological study is recorded of 50 patients in whom a diagnosis of idiopathic steatorrhea had been made and who had ;flat' jejunal biopsies. It is suggested that there is an underlying constitutional defect, not yet clearly defined, and that possibly secondary intestinal infection allows...

journal_title：Gut

authors： COOKE WT,FONE DJ,COX EV,MEYNELL MJ,GADDIE R

更新日期：1963-09-01 00:00:00

abstract：:Colorectal cancer is the second commonest cause of cancer death in the UK. An effective national screening programme is urgently required to reduce the substantial morbidity and mortality from the disease. The success of any screening programme will depend on the screening test detecting early Dukes's A carcinomas and...

journal_title：Gut

authors： Hart AR,Wicks AC,Mayberry JF

更新日期：1995-04-01 00:00:00

abstract：:Intestinal involvement in Schistosoma mansoni infection is usually confined to the ileum and colon. Duodenal infestation was diagnosed in a patient with recurrent schistosomiasis despite treatment who presented with a postoperative small bowel fistula. Duodenal schistosomiasis can be suspected on endoscopy, but must a...

journal_title：Gut

authors： Contractor QQ,Benson L,Schulz TB,Contractor TQ,Kasturi N

更新日期：1988-07-01 00:00:00

abstract：:In order to investigate further the reported beneficial effect of deglycyrrhizinated liquorice in gastric ulcer, a trial with a double-blind, cross-over design was performed. The patients were treated during two consecutive periods of four weeks each with either liquorice extract during the first period and placebo du...

journal_title：Gut

authors： Engqvist A,von Feilitzen F,Pyk E,Reichard H

更新日期：1973-09-01 00:00:00

abstract：:Patients with functional gastrointestinal disorders may have visceral sensory dysfunction so that physiological stimuli induce their symptoms. The clinical significance of altered perception-that is, its relation to clinical symptoms-remains unclear. Data indicate that sensory dysfunction is associated with altered re...

journal_title：Gut

authors： Azpiroz F

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:In treating patients with inflammatory bowel disease (IBD), how concomitant medications influence the response to infliximab is largely unexplored. We aim to evaluate whether proton pump inhibitors (PPIs) affect the response to infliximab therapy in patients with IBD. DESIGN:Patient-level data of adult patie...

journal_title：Gut

authors： Lu TX,Dapas M,Lin E,Peters T,Sakuraba A

更新日期：2020-12-17 00:00:00

abstract：OBJECTIVE:Gastric cancer (GC) remains difficult to cure due to heterogeneity in a clinical challenge and the molecular mechanisms underlying this disease are complex and not completely understood. Accumulating evidence suggests that microRNAs (miRNAs) play an important role in GC, but the role of specific miRNAs involv...

journal_title：Gut

authors： Han TS,Hur K,Xu G,Choi B,Okugawa Y,Toiyama Y,Oshima H,Oshima M,Lee HJ,Kim VN,Chang AN,Goel A,Yang HK

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To present comparative data about the performance of colorectal cancer (CRC) screening programmes in the European Union Member States (EU MSs). DESIGN:Cross-sectional study. We analysed key performance indicators-participation rate, positivity rate (PR), detection rate (DR) and positive predictive value for ...

journal_title：Gut

authors： Senore C,Basu P,Anttila A,Ponti A,Tomatis M,Vale DB,Ronco G,Soerjomataram I,Primic-Žakelj M,Riggi E,Dillner J,Elfström MK,Lönnberg S,Sankaranarayanan R,Segnan N

更新日期：2019-07-01 00:00:00

abstract：:A simple and reliable radioimmunoassay has been developed for a new gut hormone, HPP. In the primate 93% of the total PP was found in the pancreas with a small amount throughout the remaining gastrointestinal tract. HPP has been shown to be produced by a number of pancreatic apudomas and their metastases. The immunore...

journal_title：Gut

authors： Adrian TE,Bloom SR,Bryant MG,Polak JM,Heitz PH,Barnes AJ

更新日期：1976-12-01 00:00:00

abstract：:Gastric acid secretion, pepsin secretion, and fasting serum gastrin levels were measured in 23 patients with duodenal ulcer disease, divided into three groups which received either cimetidine 800 mg daily, cimetidine 1600 mg daily, or ranitidine hydrochloride 300 mg daily for eight weeks. Pentagastrin tests were carri...

journal_title：Gut

authors： Mohammed R,Holden RJ,Hearns JB,McKibben BM,Buchanan KD,Crean GP

更新日期：1983-01-01 00:00:00

abstract：:Colorectal cancer is the fourth commonest form of cancer in men with 678 000 estimated new cases per year worldwide, representing 8.9% of all new cancers. The disease is most frequent in Occidental countries and particularly so in North America, Australia, New Zealand, and parts of Europe. Prospects for colorectal can...

journal_title：Gut

authors： Langman M,Boyle P

更新日期：1998-10-01 00:00:00

abstract：:Recent evidence suggests that the production of colorectal carcinogens is facilitated when the pH of the colonic contents is alkaline. It follows that the colonic intraluminal pH of patients with colorectal neoplasms should be higher than in normal subjects. Gastrointestinal pH has been measured in 30 patients with co...

journal_title：Gut

authors： Pye G,Evans DF,Ledingham S,Hardcastle JD

更新日期：1990-12-01 00:00:00

abstract：:Liver regeneration is the common mechanism whereby a patient recovers form a liver injury. In the western world, ethanol is the single most important aetiological factor associated with liver disease, and it appears crucial to determine if ethanol interferes with liver regeneration. We studied the response to a 70% he...

journal_title：Gut

authors： Duguay L,Coutu D,Hetu C,Joly JG

更新日期：1982-01-01 00:00:00

abstract：:The medication history of patients presenting with benign oesophageal stricture is compared with an age and sex matched control population selected from the community. Fifty five out of 151 consecutive admissions to a dysphagia clinic were found to have benign oesophageal stricture. Twenty six out of 53 (49%) had been...

journal_title：Gut

authors： Wilkins WE,Ridley MG,Pozniak AL

更新日期：1984-05-01 00:00:00

abstract：:This study confirms previous reports that satisfactory gastric acid secretory responses to intravenous administration of histamine, carbachol, and gastrin can be obtained. Bilateral castration of the male rats significantly reduced acid gastric secretory responses to carbachol but not to histamine. Overiectomized rats...

journal_title：Gut

authors： Amure BO,Omole AA

更新日期：1970-08-01 00:00:00

abstract：OBJECTIVE:Pancreatic acinar cell maturation is dependent on the activity of the pancreas transcription factor 1 (PTF1) complex. Induction of pancreatitis leads to MAP kinase activation and transient suppression of the acinar differentiation programme. We investigated the role of MAP kinase-interacting kinase 1 (Mnk1) i...

journal_title：Gut

authors： Cendrowski J,Lobo VJ,Sendler M,Salas A,Kühn JP,Molero X,Fukunaga R,Mayerle J,Lerch MM,Real FX

更新日期：2015-06-01 00:00:00

abstract：:Histocompatibility (HLA) antigen phenotypes have been studied in 100 patients with ulcerative colitis, 100 with Crohn's disease, and 283 normal controls. In addition the incidence of ankylosing spondylitis, sacroiliitis, and "enteropathic" peripheral arthropathy was determined in the patients with inflammatory bowel d...

journal_title：Gut

authors： Mallas EG,Mackintosh P,Asquith P,Cooke WT

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVE:To investigate the potential tumour suppressor functions of glutathione peroxidase 7 (GPX7) and examine the interplay between epigenetic and genetic events in regulating its expression in oesophageal adenocarcinomas (OAC). DESIGN:In vitro and in vivo cell models were developed to investigate the biological a...

journal_title：Gut

authors： Peng D,Hu T,Soutto M,Belkhiri A,Zaika A,El-Rifai W

更新日期：2014-04-01 00:00:00

abstract：:The relationship between physical activity and risk of symptomatic diverticular disease has not been investigated directly. This association was examined in a prospective cohort of 47,678 American men, 40 to 75 years of age, and free of diagnosed diverticular disease, colon or rectal polyp, ulcerative colitis, and can...

journal_title：Gut

authors： Aldoori WH,Giovannucci EL,Rimm EB,Ascherio A,Stampfer MJ,Colditz GA,Wing AL,Trichopoulos DV,Willett WC

更新日期：1995-02-01 00:00:00