Performance of colorectal cancer screening in the European Union Member States: data from the second European screening report.

abstract：BACKGROUND:Experimental, clinical, and epidemiological studies have implicated mitogenic metabolites of arachidonic acid such as prostaglandin E(2) (PGE(2)) in colorectal carcinogenesis. Recently, cyclooxygenase 2 (COX-2) which catalyses the conversion of arachidonic acid to PGE(2), has displayed increased levels in hu...

journal_title：Gut

authors： Dimberg J,Samuelsson A,Hugander A,Söderkvist P

更新日期：1999-11-01 00:00:00

abstract：:Pancreatic secretion of lipase and chymotrypsin in response to elemental diets and a crushed food homogenate was studied in normal subjects. The solutions were infused at constant flow rates at the ligament of Treitz with polyethylene glycol as a nonabsorbable marker. A triple lumen tube was used, enabling collection ...

journal_title：Gut

authors： Vison N,Hecketsweiler P,Butel J,Bernier JJ

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Colonoscopic surveillance for cancer in longstanding extensive ulcerative colitis relies heavily on non-targeted mucosal biopsies. Chromoendoscopy can aid detection of subtle mucosal abnormalities. We hypothesised that routine pancolonic indigo carmine dye spraying would improve the macroscopic dete...

journal_title：Gut

authors： Rutter MD,Saunders BP,Schofield G,Forbes A,Price AB,Talbot IC

更新日期：2004-02-01 00:00:00

abstract：:Hydrogen breath tests are widely used to explore the pathophysiology of functional gastrointestinal disorders. Small intestinal bacterial overgrowth and carbohydrate malabsorption are disorders detected by these tests that have been proposed to be of great importance for symptoms in, for instance, irritable bowel synd...

journal_title：Gut

authors： Simrén M,Stotzer PO

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:As the current therapeutic strategies for human hepatocellular carcinoma (HCC) have been proven to have limited effectiveness, immunotherapy becomes a compelling way to tackle the disease. We aim to provide humanised mouse (humice) models for the understanding of the interaction between human cancer and immun...

journal_title：Gut

authors： Zhao Y,Shuen TWH,Toh TB,Chan XY,Liu M,Tan SY,Fan Y,Yang H,Lyer SG,Bonney GK,Loh E,Chang KTE,Tan TC,Zhai W,Chan JKY,Chow EK,Chee CE,Lee GH,Dan YY,Chow PK,Toh HC,Lim SG,Chen Q

更新日期：2018-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a human pathogen responsible for acute and chronic liver disease, infecting an estimated 130-170 million persons worldwide. An intriguing feature of HCV infection is its peculiar relationship with lipids: (1) HCV virions circulate in serum bound to lipoproteins; (2) lipids have been shown to...

journal_title：Gut

authors： Negro F

更新日期：2010-09-01 00:00:00

abstract：:ABO and Rhesus blood group data have been examined for 1,680 patients treated for gastric cancer in four London hospitals. The risk of developing gastric cancer was estimated to be 16% higher for group A subjects than for group O subjects, in close agreement with many previous reports throughout the world. More detail...

journal_title：Gut

authors： Glober GA,Cantrell EG,Doll R,Peto R

更新日期：1971-07-01 00:00:00

abstract：:A chronic colitis has been induced in rabbits having many of the histological features of human ulcerative colitis. Animals were first immunised with the common enterobacterial antigen of Kunin and haemagglutinating antibodies demonstrated in high titre. An immune complex colitis was then established by the injection ...

journal_title：Gut

authors： Mee AS,McLaughlin JE,Hodgson HJ,Jewell DP

更新日期：1979-01-01 00:00:00

abstract：:Though amoebic liver abscess and liver cirrhosis occur very commonly in hospital practice in the tropics, they have not to the knowledge of the present authors hitherto been reported to occur simultaneously in the same patient. The patient described here, who had clear-cut clinical and histological features of chronic...

journal_title：Gut

authors： Falaiye JM,Okeke GC,Fregene AO

更新日期：1980-02-01 00:00:00

abstract：:In conditions with increased neutrophil production, the serum total vitamin B(12)-binding capacity (TBBC) is considered to correlate with the blood pool size of neutrophil granulocytes. The serum lysozyme, on the other hand, is a measure of neutrophil (and monocyte) turnover. The mean serum TBBC was significantly rais...

journal_title：Gut

authors： Kane SP,Hoffbrand AV,Neale G

更新日期：1974-12-01 00:00:00

abstract：BACKGROUND:Integrins mediate cell matrix adhesion and regulate cell growth and survival. In colonic epithelial cells, alpha(2)beta(1) integrin controls glandular differentiation and proliferation. Butyrate stimulates differentiation and induces apoptosis in vitro. AIMS:We investigated whether butyrate induction of apo...

journal_title：Gut

authors： Buda A,Qualtrough D,Jepson MA,Martines D,Paraskeva C,Pignatelli M

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Increased expression of proinflammatory cytokines, including tumour necrosis factor alpha, interleukin 6, and interferon gamma, as well as activation of proinflammatory signalling molecules such as nuclear factor kappa B, is characteristic of inflammatory bowel disease (IBD). AIMS:To investigate expression ...

journal_title：Gut

authors： Schreiber S,Rosenstiel P,Hampe J,Nikolaus S,Groessner B,Schottelius A,Kühbacher T,Hämling J,Fölsch UR,Seegert D

更新日期：2002-09-01 00:00:00

abstract：:The prevalence of methane production in an adult population of 256 subjects was 41%, but it was significantly higher in females (49%), than males (33%). When the population was subdivided into ethnic groups. Caucasians (48%) and Black (45%) had significantly more methane producers than Orientals (24%) and Indians (32%...

journal_title：Gut

authors： Pitt P,de Bruijn KM,Beeching MF,Goldberg E,Blendis LM

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Interstitial cells of Cajal (ICC) are pacemakers and mediators of motor neurotransmission in gastrointestinal smooth muscles. ICC require cellular signalling via Kit, a receptor tyrosine kinase, for development and maintenance of phenotype. Much of the evidence demonstrating the functions of ICC com...

journal_title：Gut

authors： Takayama I,Daigo Y,Ward SM,Sanders KM,Walker RL,Horowitz B,Yamanaka T,Fujino MA

更新日期：2002-06-01 00:00:00

abstract：:Bacterial contamination of gastrointestinal fibre-endoscopes is a potential source of clinically significant infection. Aqueous 2% alkaline glutaraldehyde adequately disinfects fibre-endoscopes but may cause serious sensitivity reactions among endoscopy staff. A new 'closed-system' disinfecting apparatus is described ...

journal_title：Gut

authors： O'Connor HJ,Rothwell J,Maxwell S,Lincoln C,Axon AT

更新日期：1982-08-01 00:00:00

abstract：:The behaviour of basal and stimulated acid secretion, gastrin release, serum pepsinogen I, and gastric emptying of liquids was studied in 19 consecutive patients with Helicobacter pylori positive duodenal ulcer, over a follow up period of six months. Eleven patients were studied before and at three and six months afte...

journal_title：Gut

authors： Parente F,Maconi G,Sangaletti O,Minguzzi M,Vago L,Bianchi Porro G

更新日期：1995-08-01 00:00:00

abstract：:Primary oesophageal involvement by lymphoma in two patients, one with Hodgkin's disease and one with non-Hodgkin's lymphoma is reported. In both, there were no manifestations of the disease outside the oesophagus, which is exceptionally rare. In the patient with non-Hodgkin's lymphoma, the oesophageal tumour was the f...

journal_title：Gut

authors： Taal BG,Van Heerde P,Somers R

更新日期：1993-07-01 00:00:00

abstract：:Acute fulminant pancreatitis is associated with significant morbidity and mortality. To examine the outcome of conservative and surgical treatment of this disorder, 36 patients who survived an initial episode were restudied after a mean of six years. Fifty three per cent had developed diabetes mellitus, half of whom r...

journal_title：Gut

authors： Eriksson J,Doepel M,Widén E,Halme L,Ekstrand A,Groop L,Höckerstedt K

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND AND AIM:There is controversy regarding whether paramyxovirus infection is causally associated with inflammatory bowel disease (IBD). The latest cohort study claimed that atypical measles and mumps infections in childhood may be risk factors for later IBD. This study was conducted to clarify the validity of a...

journal_title：Gut

authors： Iizuka M,Saito H,Yukawa M,Itou H,Shirasaka T,Chiba M,Fukushima T,Watanabe S

更新日期：2001-05-01 00:00:00

abstract：:We report on clinical, nutritional, and hepatic histological findings in 50 non-selected obese subjects (mean overweight +74%; range +21-138%). The pathogenesis of the liver damage was assessed with the help of multidimensional analysis of a number of clinical variables. According to the severity of the hepatic lesion...

journal_title：Gut

authors： Braillon A,Capron JP,Hervé MA,Degott C,Quenum C

更新日期：1985-02-01 00:00:00

abstract：:The increase in activities of hepatic thymidylate synthetase (EC 2.1.1.45) and thymidine kinase (EC 2.7.1.21), which catalyse the formation of thymidylate through the de novo and salvage pathways, respectively, were significantly suppressed during liver regeneration in rats which were given glucocorticoids (hydrocorti...

journal_title：Gut

authors： Tsukamoto I,Kojo S

更新日期：1989-03-01 00:00:00

abstract：:Eighty patients were asked if they would have preferred their ileocolonic resection and anastomosis for Crohn's disease, to have been carried out sooner, later or at the same time as it was done. Seventy of the patients replied (88%). No patient would have preferred their operation to have been later, while 74% though...

journal_title：Gut

authors： Scott NA,Hughes LE

更新日期：1994-05-01 00:00:00

abstract：:In June 1990 a survey of members of the endoscopy section of the British Society of Gastroenterology showed that 47% of respondents were offering some form of open access gastroscopy (OAG). Only 10% offered true (non-censored) OAG. The survey was repeated in June 1994. The overall provision of OAG had risen to 74%, mo...

journal_title：Gut

authors： Silcock JG,Bramble MG

更新日期：1997-02-01 00:00:00

abstract：:Twenty one patients with diabetic peripheral neuropathy, 18 with idiopathic faecal incontinence and 11 normal controls were studied with techniques of mucosal electrosensitivity, rectal distension for the quantitative assessment of anorectal sensation, and manometric and electromyographic tests for the assessment of a...

journal_title：Gut

authors： Rogers J,Levy DM,Henry MM,Misiewicz JJ

更新日期：1988-06-01 00:00:00

abstract：:We report massive acute haemolysis associated with hepatitis A in a 36 year old Irish woman. Although mild anaemia is not uncommon during viral hepatitis, haemolysis of the severity observed in this patient has previously been reported only in patients with glucose-6-phosphate dehydrogenase deficiency. ...

journal_title：Gut

authors： Lyons DJ,Gilvarry JM,Fielding JF

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:To evaluate the relation between non-steroidal anti-inflammatory drugs (NSAIDs) and colitis due to inflammatory bowel disease. METHODS:A case-control study was conducted using a prospectively constructed, record linkage database containing hospital event and dispensed drug data (1989-93). The study populati...

journal_title：Gut

authors： Evans JM,McMahon AD,Murray FE,McDevitt DG,MacDonald TM

更新日期：1997-05-01 00:00:00

abstract：:This study investigated the mechanisms by which TAGH solution (a mixture of triiodothyronine, amino acids, glucagon, and heparin) induces DNA synthesis in hepatocytes in the liver of intact rats, with particular reference to events at the epidermal growth factor (EGF) receptor. Both partial hepatectomy and infusion of...

journal_title：Gut

authors： Vesey DA,Selden AC,Hodgson HJ

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The potential of endoscopic mucosal resection (EMR) for treating flat dysplastic lesions in chronic ulcerative colitis (CUC) has not been addressed so far. Historically, such lesions were referred for colectomy. Furthermore, there are only limited data to support endoscopic resection of exophytic adenoma-lik...

journal_title：Gut

authors： Hurlstone DP,Sanders DS,Atkinson R,Hunter MD,McAlindon ME,Lobo AJ,Cross SS,Thomson M

更新日期：2007-06-01 00:00:00

abstract：:Probiotic administration may exert a protective effect in colitis by preventing mucosal barrier disruption and influencing the extent of mucosal injury. ...

journal_title：Gut

authors： Gionchetti P,Lammers KM,Rizzello F,Campieri M

更新日期：2005-07-01 00:00:00

abstract：:The staining of HLA class II antigens, the presence of cells positive for interleukin-2 receptors, the proportion of crypt cells in mitosis in the jejunal biopsy specimens, and the dose of coeliac disease marker HLA-DQ genes were studied in 75 healthy family members of coeliac disease patients. Eleven had silent coeli...

journal_title：Gut

authors： Holm K,Savilahti E,Koskimies S,Lipsanen V,Mäki M

更新日期：1994-01-01 00:00:00