Isolated primary oesophageal involvement by lymphoma: a rare cause of dysphagia: two case histories and a review of other published data.

Abstract:

:Primary oesophageal involvement by lymphoma in two patients, one with Hodgkin's disease and one with non-Hodgkin's lymphoma is reported. In both, there were no manifestations of the disease outside the oesophagus, which is exceptionally rare. In the patient with non-Hodgkin's lymphoma, the oesophageal tumour was the first manifestation of lymphoma. Shortly after admission he developed a tracheo-oesophageal fistula from which he died before treatment could be started. In the patient with Hodgkin's disease, isolated oesophageal lymphoma was the first relapse after a 13 year interval free of disease. As he had previously received mediastinal irradiation he was treated with combination chemotherapy that resulted in long term survival (> five years). Several other long term survivors have been described but only after radiotherapy or surgery. These findings suggest that systemic chemotherapy may be equally successful in treating isolated primary oesophageal lymphoma, thus offering an alternative for those patients in whom local treatment is contraindicated.

journal_name

Gut

journal_title

Gut

authors

Taal BG,Van Heerde P,Somers R

doi

10.1136/gut.34.7.994

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

994-8

issue

7

eissn

0017-5749

issn

1468-3288

journal_volume

34

pub_type

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