Abdominal decompression plays a major role in early postparacentesis haemodynamic changes in cirrhotic patients with tense ascites.

abstract：OBJECTIVE:The aim of the study was to compare azathioprine versus mesalazine tablets for the prevention of clinical recurrence in patients with postoperative Crohn's disease (CD) with moderate or severe endoscopic recurrence. METHODS:This was a 1 year, double-blind, double-dummy, randomised study which took place in 2...

journal_title：Gut

authors： Reinisch W,Angelberger S,Petritsch W,Shonova O,Lukas M,Bar-Meir S,Teml A,Schaeffeler E,Schwab M,Dilger K,Greinwald R,Mueller R,Stange EF,Herrlinger KR,International AZT-2 Study Group.

更新日期：2010-06-01 00:00:00

abstract：:Gastric acid secretion, pepsin secretion, and fasting serum gastrin levels were measured in 23 patients with duodenal ulcer disease, divided into three groups which received either cimetidine 800 mg daily, cimetidine 1600 mg daily, or ranitidine hydrochloride 300 mg daily for eight weeks. Pentagastrin tests were carri...

journal_title：Gut

authors： Mohammed R,Holden RJ,Hearns JB,McKibben BM,Buchanan KD,Crean GP

更新日期：1983-01-01 00:00:00

abstract：:Gastric cancer is a major health burden worldwide and prevention is the most promising strategy to control the disease. The available scientific evidence indicates that curing Helicobacter pylori infection results in a modest retardation of the precancerous process but does not prevent all cancers. Individuals at the ...

journal_title：Gut

authors： Correa P

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Perturbation of differentiation of the crypt-villus axis of the human small intestine is associated with several intestinal disorders of clinical importance. At present, differentiation of small intestinal enterocytes in the crypt-villus axis is not well characterised. SUBJECTS AND METHODS:Expressi...

journal_title：Gut

authors： Gassler N,Newrzella D,Böhm C,Lyer S,Li L,Sorgenfrei O,van Laer L,Sido B,Mollenhauer J,Poustka A,Schirmacher P,Gretz N

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:Suboptimal adenoma detection rate (ADR) at colonoscopy is associated with increased risk of interval colorectal cancer. It is uncertain how ADR might be improved. We compared the effect of leadership training versus feedback only on colonoscopy quality in a countrywide randomised trial. DESIGN:40 colonoscopy...

journal_title：Gut

authors： Kaminski MF,Anderson J,Valori R,Kraszewska E,Rupinski M,Pachlewski J,Wronska E,Bretthauer M,Thomas-Gibson S,Kuipers EJ,Regula J

更新日期：2016-04-01 00:00:00

abstract：:The metabolism of pure radioiodine labelled Clq has been observed in five patients with ulcerative colitis, five patients with Crohn's disease, and in five control subjects. Both the fractional catabolic rate and the synthesis rate of Clq were increased in the five patients with Crohn's disease and in four of the five...

journal_title：Gut

authors： Potter BJ,Hodgson HJ,Mee AS,Jewell DP

更新日期：1979-11-01 00:00:00

abstract：:The extent to which monitoring breath hydrogen excretion provides information concerning the entry of the residues of a solid test meal into the colon was investigated in 89 normal subjects, and 11 patients with the irritable bowel syndrome. The profile of breath hydrogen concentration showed an early peak, that occur...

journal_title：Gut

authors： Read NW,Al-Janabi MN,Bates TE,Holgate AM,Cann PA,Kinsman RI,McFarlane A,Brown C

更新日期：1985-08-01 00:00:00

abstract：:Studies have been made of mucus glycoprotein biosynthesis in different regions of the lower gastrointestinal tract in normal patients and those with ulcerative colitis (UC), active or inactive, by means of 3H-glucosamine (3H-GlcNH2)--35S-sulphate double labelling of epithelial biopsy specimens under culture conditions...

journal_title：Gut

authors： Morita H,Kettlewell MG,Jewell DP,Kent PW

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:To clarify the prognostic role of tumour protein 53 (TP53) mutations in patients with oesophageal adenocarcinoma (OAC) as there is a need for biomarkers that assist in guiding management for patients with OAC. DESIGN:A systematic review was conducted using MEDLINE, Embase, PubMed and Current Contents Connect...

journal_title：Gut

authors： Fisher OM,Lord SJ,Falkenback D,Clemons NJ,Eslick GD,Lord RV

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Hippo signalling is a recently identified major oncosuppressive pathway that plays critical roles in inhibiting hepatocyte proliferation, survival and hepatocellular carcinoma (HCC) formation. Hippo kinase (Mst1 and Mst2) inhibits HCC proliferation by suppressing Yap/Taz transcription activities. As human HCC...

journal_title：Gut

authors： Kim W,Khan SK,Liu Y,Xu R,Park O,He Y,Cha B,Gao B,Yang Y

更新日期：2018-09-01 00:00:00

abstract：:T-lymphocytic infiltration of the exocrine pancreas and liver in patients with chronic pancreatitis has suggested that cell mediated immune mechanisms may play a part in the pathogenesis of this disease. As expression of major histocompatibility (MHC) antigens is a prerequisite for organ specific autoimmunity, the exp...

journal_title：Gut

authors： Jalleh RP,Gilbertson JA,Williamson RC,Slater SD,Foster CS

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Watery stools are equated with rapid and hard stools with slow intestinal transit; however, the relation between stool form and transit through specific regions of the gut is not clear cut. In addition, more information is needed on interindividual variability of these measurements. AIM:To examine the relat...

journal_title：Gut

authors： Degen LP,Phillips SF

更新日期：1996-07-01 00:00:00

abstract：AIMS:To determine risk factors for peptic ulcer bleeding other than non-steroidal anti-inflammatory drugs (NSAIDs). Methods-Data on possible antecedent risk factors obtained in a large case control study of 1121 patients admitted to hospitals in Glasgow, Newcastle, Nottingham, Oxford, and Portsmouth with bleeding pepti...

journal_title：Gut

authors： Weil J,Langman MJ,Wainwright P,Lawson DH,Rawlins M,Logan RF,Brown TP,Vessey MP,Murphy M,Colin-Jones DG

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:It has been suggested that Mycobacterium paratuberculosis is the cause of Crohn's disease. In a previous report the immediate effect of two years treatment with antituberculous chemotherapy showed no clinical benefit. AIMS:To assess both the immediate and longer term effect of treatment on the disease. MET...

journal_title：Gut

authors： Thomas GA,Swift GL,Green JT,Newcombe RG,Braniff-Mathews C,Rhodes J,Wilkinson S,Strohmeyer G,Kreuzpainter G

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The early responses of the oesophageal mucosa to acid perfusion may predict subsequent pathology. Mucosal responses to luminal acid may result either from acid permeating through the mucosa or from other unknown transduction mechanisms. In order to better understand the dynamics of acid permeation i...

journal_title：Gut

authors： Tanaka S,Chu S,Hirokawa M,Montrose MH,Kaunitz JD

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND AIMS:We followed a population based cohort of patients with inflammatory bowel disease (IBD) from Olmsted County, Minnesota, in order to analyse long term survival and cause specific mortality. MATERIAL AND METHODS:A total of 692 patients were followed for a median of 14 years. Standardised mortality ra...

journal_title：Gut

authors： Jess T,Loftus EV Jr,Harmsen WS,Zinsmeister AR,Tremaine WJ,Melton LJ 3rd,Munkholm P,Sandborn WJ

更新日期：2006-09-01 00:00:00

abstract：:The effects on gastric emptying of a solid meal of the specific 5-HT3-receptor antagonist ICS 205-930, 10 mg and 20 mg intravenously were assessed with a scintigraphic technique in 12 normals. The 50% emptying time was less, the lag phase was shorter and the post lag emptying rate was faster after 20 mg ICS 205-930 (p...

journal_title：Gut

authors： Akkermans LM,Vos A,Hoekstra A,Roelofs JM,Horowitz M

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:The mechanisms of aspirin induced gastroduodenal injury are not fully understood. Aspirin induces the release of reactive oxygen metabolites in animal models, which may contribute to mucosal injury. AIMS:To investigate the effects of aspirin administered with placebo or antioxidants on gastric mucosal react...

journal_title：Gut

authors： McAlindon ME,Muller AF,Filipowicz B,Hawkey CJ

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Faecal concentrations of the protein calprotectin have been found to be elevated in patients with colorectal neoplasia, suggesting that it might be used as a screening tool for colorectal cancer as well as adenomas. AIMS:To measure the sensitivity and specificity of faecal calprotectin for the detection of ...

journal_title：Gut

authors： Kronborg O,Ugstad M,Fuglerud P,Johne B,Hardcastle J,Scholefield JH,Vellacott K,Moshakis V,Reynolds JR

更新日期：2000-06-01 00:00:00

abstract：:A simple evocative test has been used to study pancreatic function. Serial estimations of amylase and lipase in blood serum are made at intervals up to six hours and again at 24 hours after injecting intravenously standard doses of secretin and pancreozymin. The results of 213 tests on a normal group, in pancreatic di...

journal_title：Gut

authors： BURTON P,HAMMOND EM,HARPER AA,HOWAT HT,SCOTT JE,VARLEY H

更新日期：1960-06-01 00:00:00

abstract：:The role of the proximal and distal stomach in the emptying of solids and liquids from the stomach remains unclear. We have used a dual isotope technique to quantify proximal and distal stomach emptying of a solid (100 g of 99mTc labelled liver/ground beef) liquid (either 200 ml of normal saline (eight subjects) or 25...

journal_title：Gut

authors： Collins PJ,Houghton LA,Read NW,Horowitz M,Chatterton BE,Heddle R,Dent J

更新日期：1991-06-01 00:00:00

abstract：:Seventeen paediatric patients with immunodeficiency syndromes (10 with selective IgA deficiency, four with panhypogammaglobulinaemia, and three with selective T cell deficiency) were investigated for bacterial overgrowth of the small intestine and gut permeability to macromolecules. Five of 12 patients showed viable b...

journal_title：Gut

authors： Pignata C,Budillon G,Monaco G,Nani E,Cuomo R,Parrilli G,Ciccimarra F

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Polyamines are essential for cell growth. Dietary and probably gut bacterial derived polyamines contribute significantly to the polyamine body pool. AIMS:To evaluate the influence of dietary, luminal polyamines on growth and development of different gastrointestinal organs in normally growing rats. METHODS...

journal_title：Gut

authors： Löser C,Eisel A,Harms D,Fölsch UR

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Emerging evidence suggests that highly treatment-resistant tumour-initiating cells (TICs) play a central role in the pathogenesis of pancreatic cancer. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered to be a novel anticancer agent; however, recent studies have shown th...

journal_title：Gut

authors： Kallifatidis G,Rausch V,Baumann B,Apel A,Beckermann BM,Groth A,Mattern J,Li Z,Kolb A,Moldenhauer G,Altevogt P,Wirth T,Werner J,Schemmer P,Büchler MW,Salnikov AV,Herr I

更新日期：2009-07-01 00:00:00

abstract：:125I-labelled human trypsin metabolism has been investigated in man. Three subjects received 125I-trypsin and 131I-albumin intravenously. Against a background secretin infusion (1 U/kg/h), trypsin decayed biexponentially from the serum with half-lives of 17.5, 21, and 24 minutes for the rapid disappearance phase and 5...

journal_title：Gut

authors： Lake-Bakaar G,Rubio CE,McKavanagh S,Potter BJ,Summerfield JA

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatic stellate cells (HSCs) are key participants in liver fibrosis development. 1,25(OH)(2)D(3), the active form of vitamin D, has antiproliferative properties and antifibrotic potential, as well as a role in extracellular matrix and matrix metalloproteinase (MMP) regulation in renal and lung fibro...

journal_title：Gut

authors： Abramovitch S,Dahan-Bachar L,Sharvit E,Weisman Y,Ben Tov A,Brazowski E,Reif S

更新日期：2011-12-01 00:00:00

abstract：:The actions of hydrochloric acid, natural PGE1, PGE2 and a synthetic commercial PGE1 preparation, Enisoprost (Searle) on pepsinogen synthesis and secretion were studied in canine chief cell monolayer cultures. Hydrochloric acid, applied directly to the apical surface of chief cells using culture plate inserts (Millipo...

journal_title：Gut

authors： Defize J,Hunt RH

更新日期：1989-06-01 00:00:00

abstract：:Small bowel enteropathies that are associated with an autoimmune process are often resistant to treatment. Two children with autoimmune enteropathy were treated with cyclosporin A for eight months. Both improved, as assessed by growth, small intestinal mucosal morphology, and carbohydrate absorption. Cyclosporin A is ...

journal_title：Gut

authors： Sanderson IR,Phillips AD,Spencer J,Walker-Smith JA

更新日期：1991-11-01 00:00:00

abstract：:Of 27 patients with liver disease and cryoglobulinaemia 18 proved to have paraproteins. Six of these monoclonal immunoglobulins were shown to have antibody activity, directed to human gamma globulin, alpha(1)-fetoprotein, smooth muscle, and mitochondria.Eight of the patients suffered from acute viral hepatitis, five o...

journal_title：Gut

authors： Roux ME,Florin-Christensen A,Arana RM,Doniach D

更新日期：1974-05-01 00:00:00

abstract：BACKGROUND AND AIMS:A previous study suggested that the presence of myenteric plexitis in the proximal resection margins could be predictive of early endoscopic recurrence after ileocolonic or ileal resection for Crohn's disease (CD). The aim of the present study was to assess the predictive value of plexitis for early...

journal_title：Gut

authors： Sokol H,Polin V,Lavergne-Slove A,Panis Y,Treton X,Dray X,Bouhnik Y,Valleur P,Marteau P

更新日期：2009-09-01 00:00:00