Serum amylase and serum lipase levels in man after administration of secretin and pancreozymin.

Abstract:

:A simple evocative test has been used to study pancreatic function. Serial estimations of amylase and lipase in blood serum are made at intervals up to six hours and again at 24 hours after injecting intravenously standard doses of secretin and pancreozymin. The results of 213 tests on a normal group, in pancreatic disease, in biliary and hepatic diseases have been analysed and compared with the results of duodenal intubation and an oral glucose tolerance test. A combined evocative test and oral glucose tolerance test provide evidence of pancreatic dysfunction in the majority of cases of cancer of the pancreas and chronic pancreatitis. The conditions of the test are described and the pathological lesions in which false positive evocative tests may be found are indicated. The simple evocative test provides the earliest biochemical evidence of pancreatic disease in some patients with cancer of the pancreas and chronic pancreatitis.

journal_name

Gut

journal_title

Gut

authors

BURTON P,HAMMOND EM,HARPER AA,HOWAT HT,SCOTT JE,VARLEY H

doi

10.1136/gut.1.2.125

keywords:

subject

Has Abstract

pub_date

1960-06-01 00:00:00

pages

125-39

eissn

0017-5749

issn

1468-3288

journal_volume

1

pub_type

杂志文章

相关文献

GUT文献大全
  • The detection and measurement of circulating gastrin-like activity by bioassay.

    abstract::A perfused rat stomach technique which can detect synthetic human gastrin I in amounts greater than 10 ng and measure by block assay amounts greater than 50 ng was used to study circulating gastrin-like activity in normal subjects, patients with peptic ulcer, and patients with the Zollinger-Ellison syndrome. No detect...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.13.2.88

    authors: Colin-Jones DG,Lennard-Jones JE

    更新日期:1972-02-01 00:00:00

  • Homeostatic regulation of zinc transporters in the human small intestine by dietary zinc supplementation.

    abstract:BACKGROUND:The role of intestinal transporter regulation in optimising nutrient absorption has been studied extensively in rodent and cell line models but not in human subjects. AIMS:The aim of the present study was to investigate the response in vivo of zinc transporters in the human enterocyte to dietary zinc supple...

    journal_title:Gut

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/gut.2004.041962

    authors: Cragg RA,Phillips SR,Piper JM,Varma JS,Campbell FC,Mathers JC,Ford D

    更新日期:2005-04-01 00:00:00

  • Cholestasis and liver failure with lambda-AL amyloidosis.

    abstract::Clinically significant liver involvement in systemic amyloidosis, especially with cholestasis, is rare. We report a case of primary amyloidosis with severe intrahepatic cholestasis leading to terminal liver failure. The present case is the first of its kind reported involving Lambda light chains only as the associated...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.28.7.903

    authors: Konikoff F,Mor C,Stern S,Shaklai M,Halevy J,Theodor E

    更新日期:1987-07-01 00:00:00

  • Effects of aspirin on gastric prostaglandin E (PGE) and acid output in normal subjects.

    abstract::Aspirin administration to normal subjects resulted in a reduction in gastric prostaglandin E (PGE) output. Both PGE concentration and gastric juice volume were decreased. Gastric acid output also decreased, although the difference was not statistically significant. An increased sensitivity of the PGE system to inhibit...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.17.1.54

    authors: Child C,Jubiz W,Moore JG

    更新日期:1976-01-01 00:00:00

  • Low power interstitial Nd YAG laser photocoagulation in normal and neoplastic rat colon.

    abstract::The effects of low power (1-2 Watts), long exposure (30-400 seconds), interstitial Nd YAG laser therapy on dimethylhydrazine induced rat colonic neoplasms and normal rat colon have been studied. After a single exposure with appropriate laser parameters, dimethylhydrazine induced rat colonic neoplasms underwent coagula...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.29.1.27

    authors: Matthewson K,Barton T,Lewin MR,O'Sullivan JP,Northfield TC,Bown SG

    更新日期:1988-01-01 00:00:00

  • Abnormalities of B-cell activation and immunoregulation in patients with Crohn's disease.

    abstract::We have studied B-lymphocyte function in 39 patients with Crohn's disease and 35 normal individuals using a reverse haemolytic plaque assay as the effector system. Ten patients had active Crohn's disease, the others being in an inactive state of the disease. Compared with normal individuals, the Crohn's disease patien...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.25.11.1255

    authors: Sieber G,Herrmann F,Zeitz M,Teichmann H,Rühl H

    更新日期:1984-11-01 00:00:00

  • Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome.

    abstract:BACKGROUND:Meal ingestion is often associated with exacerbation of gastrointestinal symptoms in subjects with irritable bowel syndrome (IBS). Furthermore, recent preliminary data suggest that 5-hydroxytryptamine (5-HT) concentration in platelet poor plasma is elevated following meal ingestion in some subjects with diar...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.52.5.663

    authors: Houghton LA,Atkinson W,Whitaker RP,Whorwell PJ,Rimmer MJ

    更新日期:2003-05-01 00:00:00

  • In healthy volunteers, immunohistochemistry supports squamous to columnar metaplasia as mechanism of expansion of cardia, aggravated by central obesity.

    abstract:INTRODUCTION:Recently, we showed that the length of cardiac mucosa in healthy volunteers correlated with age and obesity. We have now examined the immunohistological characteristics of this expanded cardia to determine whether it may be due to columnar metaplasia of the distal oesophagus. METHODS:We used the squamocol...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2014-308914

    authors: Derakhshan MH,Robertson EV,Yeh Lee Y,Harvey T,Ferrier RK,Wirz AA,Orange C,Ballantyne SA,Hanvey SL,Going JJ,McColl KE

    更新日期:2015-11-01 00:00:00

  • Ultrasound guided fine needle biopsy of early hepatocellular carcinoma complicating liver cirrhosis: a multicentre study.

    abstract:BACKGROUND:Because hepatic cirrhosis is a major risk factor for hepatocellular carcinoma, recent guidelines by the European Association for the Study of the Liver (EASL) on clinical management of hepatocellular carcinoma recommend periodic ultrasound surveillance of cirrhotic patients with immediate workup for nodules ...

    journal_title:Gut

    pub_type: 杂志文章,多中心研究

    doi:10.1136/gut.2003.032359

    authors: Caturelli E,Solmi L,Anti M,Fusilli S,Roselli P,Andriulli A,Fornari F,Del Vecchio Blanco C,de Sio I

    更新日期:2004-09-01 00:00:00

  • Gall bladder emptying in severe idiopathic constipation.

    abstract:BACKGROUND:It has been suggested that slow transit constipation (STC) may be part of a panenteric motor disorder. AIM:To evaluate motility of an upper gastrointestinal organ, the gall bladder, in 16 patients with STC and 20 healthy controls. METHODS:Gall bladder emptying (ultrasonography) was studied in response to n...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.45.2.264

    authors: Penning C,Gielkens HA,Delemarre JB,Lamers CB,Masclee AA

    更新日期:1999-08-01 00:00:00

  • Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study.

    abstract:BACKGROUND AND AIMS:Serrated polyposis syndrome (SPS) is associated with an increased risk of colorectal cancer (CRC). International guidelines recommend surveillance intervals of 1-2 years. However, yearly surveillance likely leads to overtreatment for many. We prospectively assessed a surveillance protocol aiming to ...

    journal_title:Gut

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1136/gutjnl-2018-318134

    authors: Bleijenberg AG,IJspeert JE,van Herwaarden YJ,Carballal S,Pellisé M,Jung G,Bisseling TM,Nagtegaal ID,van Leerdam ME,van Lelyveld N,Bessa X,Rodríguez-Moranta F,Bastiaansen B,de Klaver W,Rivero L,Spaander MC,Koornstra JJ,B

    更新日期:2020-01-01 00:00:00

  • Race-dependent association of sulfidogenic bacteria with colorectal cancer.

    abstract:OBJECTIVE:Colorectal cancer (CRC) incidence is higher in African Americans (AAs) compared with non-Hispanic whites (NHWs). A diet high in animal protein and fat is an environmental risk factor for CRC development. The intestinal microbiota is postulated to modulate the effects of diet in promoting or preventing CRC. Hy...

    journal_title:Gut

    pub_type: 杂志文章,多中心研究

    doi:10.1136/gutjnl-2016-313321

    authors: Yazici C,Wolf PG,Kim H,Cross TL,Vermillion K,Carroll T,Augustus GJ,Mutlu E,Tussing-Humphreys L,Braunschweig C,Xicola RM,Jung B,Llor X,Ellis NA,Gaskins HR

    更新日期:2017-11-01 00:00:00

  • Distribution and release of human pancreatic polypeptide.

    abstract::A simple and reliable radioimmunoassay has been developed for a new gut hormone, HPP. In the primate 93% of the total PP was found in the pancreas with a small amount throughout the remaining gastrointestinal tract. HPP has been shown to be produced by a number of pancreatic apudomas and their metastases. The immunore...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.17.12.940

    authors: Adrian TE,Bloom SR,Bryant MG,Polak JM,Heitz PH,Barnes AJ

    更新日期:1976-12-01 00:00:00

  • Hydrogen peroxide induced adenosine diphosphate ribosyl transferase (ADPRT) response in patients with inflammatory bowel disease.

    abstract::The sample population in this initial case control study of the adenosine diphosphate ribosyl transferase (ADPRT) response of inflammatory bowel disease patients included: 23 patients with ulcerative colitis (UC)-active and inactive, 13 patients with Crohn's disease (CD)-active and inactive, 14 first degree relatives ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.29.12.1680

    authors: Markowitz MM,Rozen P,Pero RW,Tobi M,Miller DG

    更新日期:1988-12-01 00:00:00

  • Hepatitis C reactivation in patients with chronic infection with genotypes 1b and 2c: a retrospective cohort study of 206 untreated patients.

    abstract:BACKGROUND:We previously described hepatitis reactivation in two carriers of the hepatitis C virus (HCV) genotype 2c. AIM:To assess the relationship between HCV genotypes and risk of hepatitis reactivation, we studied the course of aminotransferases in patients infected with the two relevant genotypes in Italy. PATIE...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.2004.048009

    authors: Rumi MG,De Filippi F,La Vecchia C,Donato MF,Gallus S,Del Ninno E,Colombo M

    更新日期:2005-03-01 00:00:00

  • Oesophageal tone in patients with achalasia.

    abstract:BACKGROUND:The diagnosis and classification of oesophageal motility disorders is currently based on assessment of the phasic contractile activity of the oesophagus. Tonic muscular contraction of the oesophageal body (oesophageal tone) has not been well characterised. AIM:To quantify oesophageal tonic activity in healt...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.41.3.291

    authors: González M,Mearin F,Vasconez C,Armengol JR,Malagelada JR

    更新日期:1997-09-01 00:00:00

  • Omeprazole in the treatment of erosive oesophagitis refractory to high dose cimetidine and ranitidine.

    abstract::Forty five patients with refractory oesophagitis, defined as persisting erosive changes or ulceration despite a minimum of three months' treatment with cimetidine 3.2 g daily or ranitidine 0.9 g daily, were treated in an open trial with omeprazole 40 mg daily for up to eight weeks. Endoscopically defined healing was o...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.31.7.745

    authors: Bardhan KD,Morris P,Thompson M,Dhande DS,Hinchliffe RF,Jones RB,Daly MJ,Carroll NJ

    更新日期:1990-07-01 00:00:00

  • General and cancer specific mortality of a population based cohort of patients with inflammatory bowel disease: the Florence Study.

    abstract:BACKGROUND:A population based epidemiological study identified all the patients diagnosed with ulcerative colitis (UC) or Crohn's disease (CD) resident in the Florence area in the period 1978-1992. AIMS:To assess the mortality of unselected patients with inflammatory bowel disease (IBD) in a Mediterranean country. ME...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.42.2.175

    authors: Palli D,Trallori G,Saieva C,Tarantino O,Edili E,D'Albasio G,Pacini F,Masala G

    更新日期:1998-02-01 00:00:00

  • Performance of colorectal cancer screening in the European Union Member States: data from the second European screening report.

    abstract:OBJECTIVE:To present comparative data about the performance of colorectal cancer (CRC) screening programmes in the European Union Member States (EU MSs). DESIGN:Cross-sectional study. We analysed key performance indicators-participation rate, positivity rate (PR), detection rate (DR) and positive predictive value for ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2018-317293

    authors: Senore C,Basu P,Anttila A,Ponti A,Tomatis M,Vale DB,Ronco G,Soerjomataram I,Primic-Žakelj M,Riggi E,Dillner J,Elfström MK,Lönnberg S,Sankaranarayanan R,Segnan N

    更新日期:2019-07-01 00:00:00

  • Studies of gut mucosal protein synthesis in a non-steroidal anti-inflammatory drug (NSAID) model of inflammatory bowel disease.

    abstract::The extent to which defects in protein synthesis occurred in an experimental indomethacin induced rat model of nonsteroidal enteropathy has been examined. Male rats (nine) were fed indomethacin (8 mg/kg/day) for three days mixed with a powdered form of chow. The control group of rats (nine) were fed the same diet for ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.33.2.242

    authors: Banerjee AK,Marway JS,Preedy VR,Peters TJ

    更新日期:1992-02-01 00:00:00

  • Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor.

    abstract:BACKGROUND:Patients with Crohn's disease suffer from intestinal bile acid malabsorption. Intestinal bile acid absorption is mediated by the apical sodium dependent bile acid transporter ASBT/IBAT (SLC10A2). In rats, ASBT is induced by glucocorticoids. AIMS:To study whether human ASBT is activated by glucocorticoids an...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.53.1.78

    authors: Jung D,Fantin AC,Scheurer U,Fried M,Kullak-Ublick GA

    更新日期:2004-01-01 00:00:00

  • Extramedullary haemopoiesis in the small bowel.

    abstract::A patient with myelofibrosis developed repeated gastrointestinal haemorrhage from the small intestine, which was found to be infiltrated with extramedullary haemopoiesis. Nineteen months later he presented with subacute intestinal obstruction; radiology and laparotomy documented progressive infiltration of the small b...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.27.7.873

    authors: Sharma BK,Pounder RE,Cruse JP,Knowles SM,Lewis AA

    更新日期:1986-07-01 00:00:00

  • Optimum bile acid treatment for rapid gall stone dissolution.

    abstract::To determine the optimum bile acid regimen for rapid gall stone dissolution, 48 gall stone patients were divided into four groups of 12 according to stone diameter and were randomly allocated to receive one of four treatment regimens: bedtime or mealtime chenodeoxycholic acid (CDCA, 12 mg/kg/day) and bedtime or mealti...

    journal_title:Gut

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/gut.33.3.381

    authors: Jazrawi RP,Pigozzi MG,Galatola G,Lanzini A,Northfield TC

    更新日期:1992-03-01 00:00:00

  • Oestrus and gasric secretion in the dog.

    abstract::Marked decreases in 24-hour Heidenhain pouch secretion, lasting from nine to 18 days, were observed in five mongrel bitches during periods of naturally occurring oestrus. Neither oophorectomy nor control celiotomy caused significant change in Heidenhain pouch secretion in bitches who were not experiencing oestrus. The...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.11.10.855

    authors: Landor JH,Wild RA

    更新日期:1970-10-01 00:00:00

  • The cardiac sphincter in the cat.

    abstract::A study of the function of the lower end of the oesophagus in the cat confirms that it behaves as a true physiological sphincter, even though histological evidence for such a structure is absent. Sphincteric action is a function of the circular muscle fibres in the lowest 2 cm. of the oesophagus. Reflex changes in ton...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.2.3.252

    authors: CLARK CG,VANE JR

    更新日期:1961-09-01 00:00:00

  • Outcomes of COVID-19 in 79 patients with IBD in Italy: an IG-IBD study.

    abstract:OBJECTIVES:COVID-19 has rapidly become a major health emergency worldwide. Patients with IBD are at increased risk of infection, especially when they have active disease and are taking immunosuppressive therapy. The characteristics and outcomes of COVID-19 in patients with IBD remain unclear. DESIGN:This Italian prosp...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2020-321411

    authors: Bezzio C,Saibeni S,Variola A,Allocca M,Massari A,Gerardi V,Casini V,Ricci C,Zingone F,Amato A,Caprioli F,Lenti MV,Viganò C,Ascolani M,Bossa F,Castiglione F,Cortelezzi C,Grossi L,Milla M,Morganti D,Pastorelli L,R

    更新日期:2020-07-01 00:00:00

  • Controlled trial comparing prednisolone with an elemental diet plus non-absorbable antibiotics in active Crohn's disease.

    abstract::In a randomised clinical trial, patients with moderately active Crohn's disease received either prednisolone 0.5 mg/kg/day plus a normal diet, or an elemental diet plus oral framycetin, colistin and nystatin. Patients were assessed using the Crohn's disease activity index (CDAI), ESR, and faecal granulocyte excretion ...

    journal_title:Gut

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/gut.26.10.994

    authors: Saverymuttu S,Hodgson HJ,Chadwick VS

    更新日期:1985-10-01 00:00:00

  • An update on the use and investigation of probiotics in health and disease.

    abstract::Probiotics are derived from traditional fermented foods, from beneficial commensals or from the environment. They act through diverse mechanisms affecting the composition or function of the commensal microbiota and by altering host epithelial and immunological responses. Certain probiotic interventions have shown prom...

    journal_title:Gut

    pub_type: 杂志文章,评审

    doi:10.1136/gutjnl-2012-302504

    authors: Sanders ME,Guarner F,Guerrant R,Holt PR,Quigley EM,Sartor RB,Sherman PM,Mayer EA

    更新日期:2013-05-01 00:00:00

  • The applicability of hepatocellular carcinoma risk prediction scores in a North American patient population with chronic hepatitis B infection.

    abstract:BACKGROUND:Patients with chronic hepatitis B (CHB) infection are at an increased risk of developing hepatocellular carcinoma (HCC). Risk scores have been developed in Asian populations to predict HCC risk over time. AIM:To assess the performance of HCC risk prediction models in a heterogeneous population of patients w...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2014-309099

    authors: Abu-Amara M,Cerocchi O,Malhi G,Sharma S,Yim C,Shah H,Wong DK,Janssen HL,Feld JJ

    更新日期:2016-08-01 00:00:00

  • Healing of protein losing hypertrophic gastropathy by eradication of Helicobacter pylori--is Helicobacter pylori a pathogenic factor in Ménétrier's disease?

    abstract::Hypertrophic gastropathy--that is, Ménétrier's disease--was found, in a retrospective analysis, to be associated with Helicobacter pylori in more than 90% of patients. It is proposed that hypertrophic gastropathy represents a special form of H pylori gastritis in these patients. A case is described of a 28 year old wo...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.35.5.701

    authors: Bayerdörffer E,Ritter MM,Hatz R,Brooks W,Ruckdeschel G,Stolte M

    更新日期:1994-05-01 00:00:00