Hepatitis C reactivation in patients with chronic infection with genotypes 1b and 2c: a retrospective cohort study of 206 untreated patients.

abstract：:Bile acid pool size and kinetics were determined in 17 patients with cirrhosis and 11 patients without liver disease and correlated with the severity of liver disease as determined by the usual clinical and laboratory criteria. In order to assess the severity of liver disease, a grading system was devised which assign...

journal_title：Gut

authors： McCormick WC 3rd,Bell CC Jr,Swell L,Vlahcevic ZR

更新日期：1973-11-01 00:00:00

abstract：:A fifth instance of Crohn's disease in identical twins is reported. The evidence for genetic expression of the disease is considered and the possible mechanisms involved are reviewed. ...

journal_title：Gut

authors： Hislop IG,Grant AK

更新日期：1969-12-01 00:00:00

abstract：:The incidence of small intestinal colonization in unoperated duodenal ulcer patients was low and similar to that in the normal population. The majority of patients seven to 10 days following truncal vagotomy and drainage were colonized whereas none of a control group of patients following simple closure of a perforate...

journal_title：Gut

authors： Browning GG,Buchan KA,Mackay C

更新日期：1974-02-01 00:00:00

abstract：BACKGROUND:Pyoderma gangrenosum (PG) is a chronic ulcerating skin condition that often occurs in association with inflammatory bowel disease. There have been a number of reports of PG responding to infliximab, a monoclonal antibody against tumour necrosis factor alpha. AIM:In the first randomised placebo controlled tr...

journal_title：Gut

authors： Brooklyn TN,Dunnill MG,Shetty A,Bowden JJ,Williams JD,Griffiths CE,Forbes A,Greenwood R,Probert CS

更新日期：2006-04-01 00:00:00

abstract：:The important issue of whether Heliobacter pylori eradication leads to increased reflux has been the subject of many apparently contradictory publications, but when we asked two leading authorities to give us their views, there turned out to be considerable consensus, as you can read below. ...

journal_title：Gut

authors： Richter JE

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:5-Lipoxygenase products play a part in inflammatory response. AIMS:The effect of intracolonic administration of zileuton (a 5-lipoxygenase inhibitor) on colonic damage and eicosanoid local release was assessed in a rat model of colitis. METHODS:Ninety rats with trinitrobenzenesulphonic acid induced colitis...

journal_title：Gut

authors： Bertrán X,Mañé J,Fernández-Bañares F,Castellá E,Bartolí R,Ojanguren I,Esteve M,Gassull MA

更新日期：1996-06-01 00:00:00

abstract：:The secretory response of gastric acid to pure ethanol and alcoholic beverages may be different because the action of the non-ethanolic contents of the beverage may overwhelm that of ethanol. Pure ethanol in low concentrations (< 5% vol/vol) is a mild stimulant of acid secretion whereas at higher concentrations it has...

journal_title：Gut

authors： Chari S,Teyssen S,Singer MV

更新日期：1993-06-01 00:00:00

abstract：:The benzimidazole anthelmintics mebendazole and fenbendazole have been shown to be much less effective against Nippostrongylus brasiliensis infections in the rat on a combined iron and protein deficient diet. In the present experiments it was shown that the anthelmintic efficacy of mebendazole was significantly impair...

journal_title：Gut

authors： Duncombe VM,Bolin TD,Davis AE,Fagan MR,Kelly JD

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Tumour vascularisation is a determinant of the development of metastases. AIMS:To measure blood flow in normal stomach and gastric adenocarcinomas by laser Doppler flowmetry and correlate blood flow with vascularisation after immunohistochemical staining of resected specimens for CD31 and von Willebrand fac...

journal_title：Gut

authors： Schilling MK,Redaelli C,Friess H,Blum B,Signer C,Maurer CA,Büchler MW

更新日期：1999-09-01 00:00:00

abstract：:In an endoscopic study of 90 consecutive patients with more than one peptic ulcer, the ulcers in an individual were profoundly spatially clustered. Clustering of ulcer locations was shown using a non-parametric test of clustering (Kruskal-Wallis statistic with 89 degrees of freedom = 151.31, probability of observing t...

journal_title：Gut

authors： Cappell MS

更新日期：1989-10-01 00:00:00

abstract：:THE SMOOTH MUSCLE SPHINCTERIC ACTIVITY OF THE ANUS IN CATS IS BASED ON TWO DISTINCT MECHANISMS: a typical anal component, characterized by anal slow pressure waves not related to spike potentials in the internal anal sphincter, and an intestinal-like pressure component related to spiking activity in the internal sphin...

journal_title：Gut

authors： Kerremans R,Penninckx F

更新日期：1970-08-01 00:00:00

abstract：OBJECTIVE:In treating patients with inflammatory bowel disease (IBD), how concomitant medications influence the response to infliximab is largely unexplored. We aim to evaluate whether proton pump inhibitors (PPIs) affect the response to infliximab therapy in patients with IBD. DESIGN:Patient-level data of adult patie...

journal_title：Gut

authors： Lu TX,Dapas M,Lin E,Peters T,Sakuraba A

更新日期：2020-12-17 00:00:00

abstract：OBJECTIVE:Gastric cancer is the third leading cause of cancer death worldwide and infection by Helicobacter pylori is the strongest risk factor. We have reported increased epidermal growth factor receptor (EGFR) phosphorylation in the H. pylori-induced human carcinogenesis cascade, and association with DNA damage. Our ...

journal_title：Gut

authors： Sierra JC,Asim M,Verriere TG,Piazuelo MB,Suarez G,Romero-Gallo J,Delgado AG,Wroblewski LE,Barry DP,Peek RM Jr,Gobert AP,Wilson KT

更新日期：2018-07-01 00:00:00

abstract：:These updated guidelines on the management of variceal haemorrhage have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines which this document supersedes were written in 2...

journal_title：Gut

authors： Tripathi D,Stanley AJ,Hayes PC,Patch D,Millson C,Mehrzad H,Austin A,Ferguson JW,Olliff SP,Hudson M,Christie JM,Clinical Services and Standards Committee of the British Society of Gastroenterology.

更新日期：2015-11-01 00:00:00

abstract：:The value of four tests to detect occult alimentary blood loss has been compared in normal subjects, in patients with and without alimentary disease, and in patients with congestive heart failure, and the sensitivities of these tests have been compared using suspensions of blood alone and blood in faeces. The Occultes...

journal_title：Gut

authors： Steingold L,Roberts AA

更新日期：1961-03-01 00:00:00

abstract：:We report on clinical, nutritional, and hepatic histological findings in 50 non-selected obese subjects (mean overweight +74%; range +21-138%). The pathogenesis of the liver damage was assessed with the help of multidimensional analysis of a number of clinical variables. According to the severity of the hepatic lesion...

journal_title：Gut

authors： Braillon A,Capron JP,Hervé MA,Degott C,Quenum C

更新日期：1985-02-01 00:00:00

abstract：:The extent to which monitoring breath hydrogen excretion provides information concerning the entry of the residues of a solid test meal into the colon was investigated in 89 normal subjects, and 11 patients with the irritable bowel syndrome. The profile of breath hydrogen concentration showed an early peak, that occur...

journal_title：Gut

authors： Read NW,Al-Janabi MN,Bates TE,Holgate AM,Cann PA,Kinsman RI,McFarlane A,Brown C

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:Precancerous lesion, a well-established histopathologically premalignant tissue with the highest risk for tumourigenesis, develops preferentially from activation of DNA damage checkpoint and persistent inflammation. However, little is known about the mechanisms by which precancerous lesions are initiated and ...

journal_title：Gut

authors： Yang Y,Lin X,Lu X,Luo G,Zeng T,Tang J,Jiang F,Li L,Cui X,Huang W,Hou G,Chen X,Ouyang Q,Tang S,Sun H,Chen L,Gonzalez FJ,Wu M,Cong W,Chen L,Wang H

更新日期：2016-07-01 00:00:00

abstract：:The aim of this study was to develop and validate an endoscopic index for assessing the severity of Crohn's disease. Endoscopic findings were prospectively collected by a multicentre group in 75 patients with Crohn's colitis according to a previously validated procedure. The presence of nine preselected lesions was re...

journal_title：Gut

authors： Mary JY,Modigliani R

更新日期：1989-07-01 00:00:00

abstract：:To determine the optimum dose of ispaghula husk in patients with irritable bowel syndrome (IBS) and to assess the correlation, if any between the relief in patients' symptoms and the whole gut transit time, and the increase in stool weight, a two part study was carried out. In part 1, 14 male patients were given ispag...

journal_title：Gut

authors： Kumar A,Kumar N,Vij JC,Sarin SK,Anand BS

更新日期：1987-02-01 00:00:00

abstract：:Rapid growth of a transplantable insulinoma in rats over a 14 day period results in hyperphagia together with a selective increase in the weight and enteroglucagon (GLI) concentration of the small intestine. Measurement of serotonin concentrations by an HPLC/fluorometric method demonstrated an increase in blood (91%; ...

journal_title：Gut

authors： Conlon JM,Bailey CJ,Flatt PR

更新日期：1987-01-01 00:00:00

abstract：:Eighteen patients with achalasia of the cardia diagnosed by radiography, endoscopy, and manometry were subjected to forced pneumatic dilatation under fluoroscopic control. The procedure was uneventful in all but one patient who developed a pneumomediastinum which resolved on conservative management. A satisfactory res...

journal_title：Gut

authors： Lishman AH,Dellipiani AW

更新日期：1982-06-01 00:00:00

abstract：:A clinical, biochemical, and pathological study is recorded of 50 patients in whom a diagnosis of idiopathic steatorrhea had been made and who had ;flat' jejunal biopsies. It is suggested that there is an underlying constitutional defect, not yet clearly defined, and that possibly secondary intestinal infection allows...

journal_title：Gut

authors： COOKE WT,FONE DJ,COX EV,MEYNELL MJ,GADDIE R

更新日期：1963-09-01 00:00:00

abstract：:On three occasions, a 63 year old housewife with hyperthyroidism developed a reaction which included fever, pruritus, malaise, and, on one occasion, jaundice one to 17 days after taking carbimazole. Challenge with carbimazole was followed within 12 hours by abdominal pain, pruritus, and increased serum transaminase le...

journal_title：Gut

authors： Lunzer M,Huang SN,Ginsburg J,Ahmed M,Sherlock S

更新日期：1975-11-01 00:00:00

abstract：INTRODUCTION:Recent data have suggested that specific haplotypic variants of the DLG5 gene on chromosome 10q23 may be associated with susceptibility to inflammatory bowel disease (IBD) in Germany. Haplotype D, notably characterised by the presence of a G-->A substitution at nucleotide 113, was associated with susceptib...

journal_title：Gut

authors： Noble CL,Nimmo ER,Drummond H,Smith L,Arnott ID,Satsangi J

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:It is presently not well understood to what extent peptic ulcer and gastric cancer represent related diseases. AIMS:The objective of this study was to assess past occurrence of gastric and duodenal ulcers in patients with cancer of the gastric cardia or other parts of the stomach. METHODS:The association b...

journal_title：Gut

authors： Molloy RM,Sonnenberg A

更新日期：1997-02-01 00:00:00

abstract：:Intestinal protein loss in chronic inflammatory bowel diseases may be easily determined by measurement of alpha-1-antitrypsin (alpha 1-AT) stool concentration and alpha 1-AT clearance. Both parameters were significantly raised in 36 and 34 patients respectively with chronic inflammatory bowel diseases, compared with e...

journal_title：Gut

authors： Fischbach W,Becker W,Mössner J,Koch W,Reiners C

更新日期：1987-04-01 00:00:00

abstract：:Five patients in whom small-intestinal bypass was performed for severe obesity had a second operation 11-19 months later because of insufficient weight loss. Mucosal enzyme activities and histological appearance were investigated in biopsies from different parts of the functioning and excluded small intestine. These w...

journal_title：Gut

authors： Asp NG,Gudmand-Høyer E,Andersen B,Berg NO

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVE:Patients with a history of Helicobacter pylori-negative idiopathic bleeding ulcers have a considerable risk of recurrent ulcer complications. We hypothesised that a proton pump inhibitor (lansoprazole) is superior to a histamine 2 receptor antagonist (famotidine) for the prevention of recurrent ulcer bleeding...

journal_title：Gut

authors： Wong GLH,Lau LHS,Ching JYL,Tse YK,Ling RHY,Wong VWS,Chiu PWY,Lau JYW,Chan FKL

更新日期：2020-04-01 00:00:00

abstract：AIMS:To determine risk factors for peptic ulcer bleeding other than non-steroidal anti-inflammatory drugs (NSAIDs). Methods-Data on possible antecedent risk factors obtained in a large case control study of 1121 patients admitted to hospitals in Glasgow, Newcastle, Nottingham, Oxford, and Portsmouth with bleeding pepti...

journal_title：Gut

authors： Weil J,Langman MJ,Wainwright P,Lawson DH,Rawlins M,Logan RF,Brown TP,Vessey MP,Murphy M,Colin-Jones DG

更新日期：2000-01-01 00:00:00