Faecal alpha-1-antitrypsin and excretion of 111indium granulocytes in assessment of disease activity in chronic inflammatory bowel diseases.

abstract：:Ultrastructural examination of biopsies showing Helicobacter pylori associated chronic gastritis reveals close attachment between gastric surface epithelial cells and the organism. The finding of 'adhesion pedestals', which represents a cellular response to the presence of the organism, is analogous to the response of...

journal_title：Gut

authors： Hessey SJ,Spencer J,Wyatt JI,Sobala G,Rathbone BJ,Axon AT,Dixon MF

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:The development of clinical disease after infection with Helicobacter pylori has been reported to be associated with expression of the cagA gene. Recently, it has been shown that cagA is part of a multigene locus, described as the cag pathogenicity island (PAI). The role of this region in determining clinica...

journal_title：Gut

authors： Jenks PJ,Mégraud F,Labigne A

更新日期：1998-12-01 00:00:00

abstract：:In a study of low dose interferon alfa-2b in 587 patients expected to show a good response to treatment, 76-87% patients in different countries had alanine amino-transferase activities returned to normal after four months' treatment, 49-72% were negative for hepatitis B virus (HBV)-DNA, 51-66% were negative for hepati...

journal_title：Gut

authors： Mauracher E

更新日期：1993-01-01 00:00:00

abstract：:Two consecutive trials of out-patient treatment for mild cases of active ulcerative colitis are described. In the first trial oral prednisone gave significantly better results than a placebo. In the second trial "salazopyrin" gave final results approaching those of prednisone, although over a longer time and with a hi...

journal_title：Gut

authors： LENNARD-JONES JE,LONGMORE AJ,NEWELL AC,WILSON CW,JONES FA

更新日期：1960-09-01 00:00:00

abstract：METHODS:Four patients with clinicopathological features suggesting a new distinct entity defining extensive small intestinal CD4 T cell infiltration were observed. RESULTS:All four patients presented with chronic diarrhoea, malabsorption, and weight loss. Biopsy specimens of the small intestine disclosed extensive and...

journal_title：Gut

authors： Carbonnel F,d'Almagne H,Lavergne A,Matuchansky C,Brouet JC,Sigaux F,Beaugerie L,Nemeth J,Coffin B,Cosnes J,Gendre JP,Rambaud JC

更新日期：1999-11-01 00:00:00

abstract：:Levels of clotting factors II, V, and VII were measured on admission and then daily in 12 patients with grade IV hepatic coma due to fulminant hepatic failure. Factor VII levels obtained within 36 hours of the development of grade IV coma were not of value in predicting which patients would subsequently recover consci...

journal_title：Gut

authors： Gazzard BG,Henderson JM,Williams R

更新日期：1976-07-01 00:00:00

abstract：:The effects of the methyl ester analogue of prostaglandin E1, misoprostol, on gastric epithelial cell proliferation were investigated in six dogs given 300 micrograms/kg/day of misoprostol orally for 11 weeks and in six control dogs given placebo for 11 weeks. Misoprostol treatment resulted in a 36% increase in stomac...

journal_title：Gut

authors： Goodlad RA,Madgwick AJ,Moffatt MR,Levin S,Allen JL,Wright NA

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe inflammatory diseases, but the responsiveness of GI epithelial cells to bacterial stimulation remains unclear. DESIGN:We gene...

journal_title：Gut

authors： Kayisoglu O,Weiss F,Niklas C,Pierotti I,Pompaiah M,Wallaschek N,Germer CT,Wiegering A,Bartfeld S

更新日期：2020-06-22 00:00:00

abstract：:Small intestinal mucosa obtained from six fasting patients with cholera by a peroral biopsy technique was studied with the electron microscope. The cultures of their rectal swabs were all positive for Vibrio cholerae. In the absorptive cells, large pseudopod-like cytoplasmic processes with deformed microvilli or witho...

journal_title：Gut

authors： Asakura H,Tsuchiya M,Watanabe Y,Enomoto Y,Morita A

更新日期：1974-07-01 00:00:00

abstract：BACKGROUND:Lipids may exacerbate symptoms induced by gut stimuli. AIM:To determine the mechanism whereby fat exerts this effect. SUBJECTS:Twenty four healthy subjects were studied during fasting. METHODS:We measured perception (0-6 scale) in response to jejunal balloon distension and transmucosal electrical nerve st...

journal_title：Gut

authors： Accarino AM,Azpiroz F,Malagelada JR

更新日期：2001-05-01 00:00:00

abstract：:Patients with chronic active hepatitis or alcoholic cirrhosis have serum antibodies to many more serotypes of Escherichia coli than do patients with primary biliary cirrhosis or cryptogenic cirrhosis, or normal controls. They also have antibodies against more serotypes than cirrhotic patients with a portacaval shunt. ...

journal_title：Gut

authors： Simjee AE,Hamilton-Miller JM,Thomas HC,Brumfitt W,Sherlock S

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Pancreatic cancer is among the most dismal of human malignancies. Current therapeutic strategies are virtually ineffective in controlling advanced, metastatic disease. Recent evidence suggests that the Hedgehog signalling pathway is aberrantly reactivated in the majority of pancreatic cancers, and t...

journal_title：Gut

authors： Feldmann G,Habbe N,Dhara S,Bisht S,Alvarez H,Fendrich V,Beaty R,Mullendore M,Karikari C,Bardeesy N,Ouellette MM,Yu W,Maitra A

更新日期：2008-10-01 00:00:00

abstract：:Eluates were prepared by high salt extraction from normal colonic mucosa and adenocarcinomatous tissue from 28 patients, eight more from unmatched colonic tissue and five from patients with other gastrointestinal disease. Immunoglobulins were detected by ELISA: IgG was present in 24% eluates from normal colon and 21% ...

journal_title：Gut

authors： Grail A,Norval M

更新日期：1985-10-01 00:00:00

abstract：:Three methods for dispensing nutritional solutions are compared in 48 patients with gastrointestinal diseases on intravenous nutrition during 3582 days. The protocol for intravenous nutrition applied by the nursing team and the solutions used were the same in the three groups. In group A standard bottles were used, wh...

journal_title：Gut

authors： Messing B,Beliah M,Girard-Pipau F,Leleve D,Bernier JJ

更新日期：1982-04-01 00:00:00

abstract：:Cholestasis of pregnancy is associated with increased fetal morbidity and mortality and should be treated actively. The significance attached to pruritus in pregnancy is often minimal, but it is a cardinal symptom of cholestasis of pregnancy, which may have no other clinical features. Eight women with previous cholest...

journal_title：Gut

authors： Davies MH,da Silva RC,Jones SR,Weaver JB,Elias E

更新日期：1995-10-01 00:00:00

abstract：:Family histories were obtained from 50 patients with adenocarcinoma of the colon or rectum in north-east Scotland. A comparable control group was similarly interviewed and in each group the case notes of the first degree relatives were studied where possible. Eight (16%) of the patients with cancer of the colon or rec...

journal_title：Gut

authors： Duncan JL,Kyle J

更新日期：1982-02-01 00:00:00

abstract：:Intravenous cholangiograms were performed on 100 unselected nonicteric patients using methylglucamine ioglycamide (Biligram). Fifty patients received 10.5 g of contrast medium and 50 received 5.25 g of medium. The contrast medium was injected evenly over five minutes. Side effects were recorded in only 13% of patients...

journal_title：Gut

authors： Parkin GJ,Herlinger H

更新日期：1974-04-01 00:00:00

abstract：BACKGROUND:Almost 4% of the population suffer from food allergy which is an adverse reaction to food with an underlying immunological mechanism. AIMS:To characterise one of the most frequent IgE defined food allergens, fish parvalbumin. METHODS:Tissue and subcellular distribution of carp parvalbumin was analysed by i...

journal_title：Gut

authors： Bugajska-Schretter A,Grote M,Vangelista L,Valent P,Sperr WR,Rumpold H,Pastore A,Reichelt R,Valenta R,Spitzauer S

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:There is a need for an improved biomarker for colorectal cancer (CRC) and advanced adenoma. We evaluated faecal microbial markers for clinical use in detecting CRC and advanced adenoma. DESIGN:We measured relative abundance of Fusobacterium nucleatum (Fn), Peptostreptococcus anaerobius (Pa) and Parvimonas mi...

journal_title：Gut

authors： Wong SH,Kwong TNY,Chow TC,Luk AKC,Dai RZW,Nakatsu G,Lam TYT,Zhang L,Wu JCY,Chan FKL,Ng SSM,Wong MCS,Ng SC,Wu WKK,Yu J,Sung JJY

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND AIMS:While patients with Barrett's oesophagus develop oesophageal adenocarcinoma more frequently than the general population, it has controversially been suggested that gastro-oesophageal reflux (GORD) itself is a more important determinant of risk. In order to assess the validity of this suggestion, we ...

journal_title：Gut

authors： Solaymani-Dodaran M,Logan RF,West J,Card T,Coupland C

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Whole body catabolism as the result of intrahepatic metabolic derangement is common in liver transplant candidates. However, individual nutritional assessment parameters lack sensitivity and specificity in determining energy status of these patients. Recently, serum hepatocyte growth factor (HGF) has been sh...

journal_title：Gut

authors： Miki C,Mayer AD,Buckels JA,Iriyama K,Suzuki H,McMaster P

更新日期：1999-06-01 00:00:00

abstract：:The effect of 28 days' continuous administration of oral indomethacin on gastroduodenal morphology, gastric mucosal blood flow, and gastric mucosal prostaglandin E2 (PGE2) metabolism in man was studied to define further the mechanisms of mucosal injury induced by indomethacin. Indomethacin caused acute gastroduodenal ...

journal_title：Gut

authors： Shorrock CJ,Rees WD

更新日期：1992-02-01 00:00:00

abstract：:Gastric acid secretion, pepsin secretion, and fasting serum gastrin levels were measured in 23 patients with duodenal ulcer disease, divided into three groups which received either cimetidine 800 mg daily, cimetidine 1600 mg daily, or ranitidine hydrochloride 300 mg daily for eight weeks. Pentagastrin tests were carri...

journal_title：Gut

authors： Mohammed R,Holden RJ,Hearns JB,McKibben BM,Buchanan KD,Crean GP

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND/AIMS/METHODS:During hepatic vein catheterisation, in addition to measurement of hepatic venous pressure gradient (HVPG), iodine wedged retrograde portography can be easily obtained. However, it rarely allows correct visualisation of the portal vein. Recently, CO(2) has been suggested to allow better angiogra...

journal_title：Gut

authors： Debernardi-Venon W,Bandi JC,García-Pagán JC,Moitinho E,Andreu V,Real M,Escorsell A,Montanyá X,Bosch J

更新日期：2000-06-01 00:00:00

abstract：:There has been a vast increase in GI literature focused on the use of machine learning in endoscopy. The relative novelty of this field poses a challenge for reviewers and readers of GI journals. To appreciate scientific quality and novelty of machine learning studies, understanding of the technical basis and commonly...

journal_title：Gut

authors： van der Sommen F,de Groof J,Struyvenberg M,van der Putten J,Boers T,Fockens K,Schoon EJ,Curvers W,de With P,Mori Y,Byrne M,Bergman JJGHM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND/AIMS:Studies in animals suggest a physiological role for glucagon-like peptide-1-(7-36)-amide (GLP-1) in regulating satiety. The role of GLP-1 in regulating food intake in man has, however, not been investigated. Subjects-Sixteen healthy male subjects were examined in a double blind placebo controlled fashio...

journal_title：Gut

authors： Gutzwiller JP,Göke B,Drewe J,Hildebrand P,Ketterer S,Handschin D,Winterhalder R,Conen D,Beglinger C

更新日期：1999-01-01 00:00:00

abstract：AIMS:To evaluate the clinical utility of two new tests for serum trypsinogen 2 and trypsin 2-alpha 1 antitrypsin complex (trypsin 2-AAT) in diagnosing and assessing the severity of acute pancreatitis (AP) induced by endoscopic retrograde cholangiopancreatography (ERCP). PATIENTS:Three hundred and eight consecutive pat...

journal_title：Gut

authors： Kemppainen E,Hedström J,Puolakkainen P,Halttunen J,Sainio V,Haapiainen R,Kivilaakso E,Stenman UH

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Cholera toxin produces intestinal secretion by activation of the adenylate cyclase complex. However animal studies have shown 5-hydroxytryptamine may be released after exposure to cholera toxin, and thereby contribute to the secretory state. AIM:To determine whether cholera toxin releases 5-hydroxytryptamin...

journal_title：Gut

authors： Bearcroft CP,Perrett D,Farthing MJ

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Major histocompatibility complex class II deficient (Aalpha0/0) mice have decreased CD4+ T cells, making them immunologically similar to patients with acquired immunodeficiency syndrome (AIDS). Both patients with AIDS and Aalpha0/0 mice have hypertrophic gastric folds. To clarify the mechanism of ga...

journal_title：Gut

authors： Fukui T,Nishio A,Okazaki K,Uza N,Ueno S,Kido M,Inoue S,Kitamura H,Kiriya K,Ohashi S,Asada M,Tamaki H,Matsuura M,Kawasaki K,Suzuki K,Uchida K,Fukui H,Nakase H,Watanabe N,Chiba T

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Helicobacter pylori (H pylori) infection is a major risk factor in the development of distal gastric adenocarcinoma. Development of the invasive phenotype is associated with the phenomenon of epithelial:mesenchymal transition (EMT). Soluble heparin-binding epidermal growth factor (HB-EGF) has been i...

journal_title：Gut

authors： Yin Y,Grabowska AM,Clarke PA,Whelband E,Robinson K,Argent RH,Tobias A,Kumari R,Atherton JC,Watson SA

更新日期：2010-08-01 00:00:00