Serum hepatocyte growth factor as an index of extensive catabolism of patients awaiting liver transplantation.

abstract：BACKGROUND:Zinc carnosine (ZnC) is a health food product claimed to possess health-promoting and gastrointestinal supportive activity. Scientific evidence underlying these claims is, however, limited. AIM:To examine the effect of ZnC on various models of gut injury and repair, and in a clinical trial. METHODS:In vitr...

journal_title：Gut

authors： Mahmood A,FitzGerald AJ,Marchbank T,Ntatsaki E,Murray D,Ghosh S,Playford RJ

更新日期：2007-02-01 00:00:00

abstract：:It is well known that chronic encephalopathy may be a major complication after the establishment of a surgical portal caval shunt for an episode of variceal haemorrhage. In an effort to minimise this problem Warren and colleagues developed the distal splenorenal shunt where the portal and mesenteric blood flow to the ...

journal_title：Gut

authors： Bleasel AF,Waugh RC,McCaughan GW

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:Hepatitis D virus (HDV) is a defective virus that completes its life cycle only with hepatitis B virus (HBV). The HBV with HDV super-infection has been considered as one of the most severe forms of the chronic viral hepatitis. However, there is a scarcity of data on the global burden of HDV infection. DESIGN...

journal_title：Gut

authors： Chen HY,Shen DT,Ji DZ,Han PC,Zhang WM,Ma JF,Chen WS,Goyal H,Pan S,Xu HG

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed medications, but they are associated with a number of serious adverse effects, including hypertension, cardiovascular disease, kidney injury and GI complications. OBJECTIVE:To develop a set of multidisciplinary recommenda...

journal_title：Gut

authors： Szeto CC,Sugano K,Wang JG,Fujimoto K,Whittle S,Modi GK,Chen CH,Park JB,Tam LS,Vareesangthip K,Tsoi KKF,Chan FKL

更新日期：2020-04-01 00:00:00

abstract：:The problems associated with recurrent Crohn's disease were examined in a series of 168 patients who had undergone primary resection for this condition at the General Infirmary at Leeds from 1939 to 1968 inclusive. The overall recurrence rate was 34.2%. The risk of recurrence was less in patients with involvement main...

journal_title：Gut

authors： De Dombal FT,Burton I,Goligher JC

更新日期：1971-07-01 00:00:00

abstract：:Five patients in whom small-intestinal bypass was performed for severe obesity had a second operation 11-19 months later because of insufficient weight loss. Mucosal enzyme activities and histological appearance were investigated in biopsies from different parts of the functioning and excluded small intestine. These w...

journal_title：Gut

authors： Asp NG,Gudmand-Høyer E,Andersen B,Berg NO

更新日期：1979-07-01 00:00:00

abstract：AIM:Recurrent bleeding after initial haemostasis is an important factor that directly relates to the outcome in the management of peptic ulcer bleeding. Conflicting reports have been published concerning the effectiveness of scheduled second therapeutic endoscopy on ulcer rebleeding. We investigate the use of scheduled...

journal_title：Gut

authors： Chiu PW,Lam CY,Lee SW,Kwong KH,Lam SH,Lee DT,Kwok SP

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Substance P (SP) is a pro-inflammatory neuropeptide in colitis, whereas sympathetic neurotransmitters are anti-inflammatory at high concentrations. AIM AND METHODS:In all layers of the colon, nerve fibre densities of SP(+) and sympathetic nerve fibres were investigated (22 Crohn's disease, six diverticuliti...

journal_title：Gut

authors： Straub RH,Grum F,Strauch U,Capellino S,Bataille F,Bleich A,Falk W,Schölmerich J,Obermeier F

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Chronic idiopathic intestinal pseudo-obstruction (CIIP) is characterised by severe impairment of intestinal propulsive motility that mimics bowel obstruction. JC virus (JCV) is a polyomavirus that can infect brain glial cells causing a fatal disease, but may also be found throughout the normal gastr...

journal_title：Gut

authors： Selgrad M,De Giorgio R,Fini L,Cogliandro RF,Williams S,Stanghellini V,Barbara G,Tonini M,Corinaldesi R,Genta RM,Domiati-Saad R,Meyer R,Goel A,Boland CR,Ricciardiello L

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:"Probiotic" bacteria are effective in treating some inflammatory bowel diseases. However which bacteria confer benefit and mechanisms of action remain poorly defined. Dendritic cells, which are pivotal in early bacterial recognition, tolerance induction, and shaping of T cell responses, may be central in med...

journal_title：Gut

authors： Hart AL,Lammers K,Brigidi P,Vitali B,Rizzello F,Gionchetti P,Campieri M,Kamm MA,Knight SC,Stagg AJ

更新日期：2004-11-01 00:00:00

abstract：:Motilin is a hormonal peptide found in the duodenum and jejunum which potently influences gastrointestinal tract motility. Its role in human physiology is not yet established. After a standard hospital lunch the plasma concentration of motilin showed a small, transient, but significant rise in 28 healthy subjects. Ind...

journal_title：Gut

authors： Christofides ND,Bloom SR,Besterman HS,Adrian TE,Ghatei MA

更新日期：1979-02-01 00:00:00

abstract：:A group of 80 patients with diseases of the small intestine were given a standardized psychiatric assessment every time they attended the outpatients' department over a period of a year. Forty-six patients with idiopathic steatorrhoea, 23 patients with Crohn's disease, and 11 patients with alactasia were interviewed o...

journal_title：Gut

authors： Goldberg D

更新日期：1970-06-01 00:00:00

abstract：BACKGROUND:Intestinal metaplasia, whether in the cardia or the distal oesophagus, has been uniformly defined as specialised columnar epithelium, suggesting a relation with Barrett's oesophagus. It is, however, not clear whether the risk factors associated with intestinal metaplasia are identical at both sites. AIMS:To...

journal_title：Gut

authors： Hackelsberger A,Günther T,Schultze V,Manes G,Dominguez-Muñoz JE,Roessner A,Malfertheiner P

更新日期：1998-07-01 00:00:00

abstract：:The nervous system in the intestine controls motility, secretion, sensory perception, and immune function. Peptidergic neurones with neurotransmitters such as substance P and nerve growth factors have been the main focus of neuroimmunomodulation research in the gut. This review summarises the present knowledge concern...

journal_title：Gut

authors： Straub RH,Wiest R,Strauch UG,Härle P,Schölmerich J

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:Emerging evidence from mouse models suggests that mutant Kras can drive the development of pancreatic ductal adenocarcinoma (PDA) precursors from acinar cells by enforcing ductal de-differentiation at the expense of acinar identity. Recently, human genome-wide association studies have identified NR5A2, a key...

journal_title：Gut

authors： von Figura G,Morris JP 4th,Wright CV,Hebrok M

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Lower GI bleeding (LGIB) is a common reason for emergency hospital admission, although there is paucity of data on presentations, interventions and outcomes. In this nationwide UK audit, we describe patient characteristics, interventions including endoscopy, radiology and surgery as well as clinical outcomes....

journal_title：Gut

authors： Oakland K,Guy R,Uberoi R,Hogg R,Mortensen N,Murphy MF,Jairath V,UK Lower GI Bleeding Collaborative.

更新日期：2018-04-01 00:00:00

abstract：:Carbenoxolone (Biogastrone, Berk) has been shown to reduce the peptic activity and total acidity of gastric juice obtained from anaesthetized pylorus-ligated rats without affecting significantly the volume of gastric juice secreted or the K(+) concentration. Glycyrrhetinic acid was less potent in reducing peptic activ...

journal_title：Gut

authors： Henman FD

更新日期：1970-04-01 00:00:00

abstract：:The experience of The Middlesex Hospital in the investigation and management of chronic intestinal arterial occlusion (IAO) over a 20 year period is presented. Of some 100 patients referred only 28 were found to have IAO and these were critically evaluated in terms of insorptive and exsorptive function. No relation wa...

journal_title：Gut

authors： Marston A,Clarke JM,Garcia Garcia J,Miller AL

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Integrins are transmembrane cell surface receptors that mediate cell-cell and cell-matrix contacts. Integrin-linked kinase (ILK) is the binding partner of beta1 and beta3 integrins, and has been ascribed essential roles in development, angiogenesis and tumourigenesis. However, in vivo evidence for the latter...

journal_title：Gut

authors： Assi K,Mills J,Owen D,Ong C,St Arnaud R,Dedhar S,Salh B

更新日期：2008-07-01 00:00:00

abstract：:Lymphangiomas are rare tumours of lymphatic vessels, most commonly found in children. We present the unusual case of small bowel obstruction caused by benign lymphangioma in a middle aged woman. ...

journal_title：Gut

authors： Campbell WJ,Irwin ST,Biggart JD

更新日期：1991-12-01 00:00:00

abstract：:The effect of the unconjugated bile acids, cholic, deoxycholic, chenodeoxycholic, and ursodeoxycholic acids, and of the conjugated bile acid taurocholic acid on the mucosal-to-serosal transport and tissue uptake of the naturally occurring folate derivative, 5-methyltetrahydrofolate (5-CH3H4PteGlu) was examined in ever...

journal_title：Gut

authors： Said HM,Hollander D,Strum WB

更新日期：1984-12-01 00:00:00

abstract：:Perhexiline maleate is an antianginal agent which depends on hepatic oxidation for its elimination. Its use may be complicated by the development of peripheral neuropathy and liver damage. The majority of patients with perhexiline neuropathy have an impaired ability to effect metabolic drug oxidation which is genetica...

journal_title：Gut

authors： Morgan MY,Reshef R,Shah RR,Oates NS,Smith RL,Sherlock S

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVES:The postinfectious irritable bowel syndrome (PI-IBS) suggests that impaired resolution of inflammation could cause IBS symptoms. The authors hypothesised that polymorphisms in genes whose expression were altered by gastroenteritis might be linked to IBS with diarrhoea (IBS-D) which closely resembles PI-IBS. ...

journal_title：Gut

authors： Swan C,Duroudier NP,Campbell E,Zaitoun A,Hastings M,Dukes GE,Cox J,Kelly FM,Wilde J,Lennon MG,Neal KR,Whorwell PJ,Hall IP,Spiller RC

更新日期：2013-07-01 00:00:00

abstract：CLINICAL PRESENTATION:A 28-year-old woman presented with a 3-year history of chronic watery diarrhoea along with abdominal pain and bloating, which could mostly be alleviated after defecation. Her symptom of diarrhoea, at least three times a day, could be relieved by neither probiotics nor antidiarrhoeal agents. She ha...

journal_title：Gut

authors： Zhou CB,Lu H,Chen YX,Fang JY

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:As pathogen sensors, Toll-like receptors (TLR) play a role in the first defence line during HCV infection. However, the impact of the DNA sensor TLR9 on the natural course of HCV infection is unknown. To address this, TLR9 promoter polymorphisms (single nucleotide polymorphisms (SNPs)) rs187084 and rs5743836 ...

journal_title：Gut

authors： Fischer J,Weber ANR,Böhm S,Dickhöfer S,El Maadidi S,Deichsel D,Knop V,Klinker H,Möller B,Rasenack J,Wang L,Sharma M,Hinrichsen H,Spengler U,Buggisch P,Sarrazin C,Pawlita M,Waterboer T,Wiese M,Probst-Müller E,Malin

更新日期：2017-10-01 00:00:00

abstract：:The influence of ischaemia and revascularisation on lipid peroxidation and phospholipid metabolism in the rat small intestinal mucosa was investigated. Two hours of total ischaemia followed by five minutes of revascularisation caused not only accumulation of malondialdehyde in the mucosa, but also increased activity o...

journal_title：Gut

authors： Otamiri T,Franzén L,Lindmark D,Tagesson C

更新日期：1987-11-01 00:00:00

abstract：:The effects of pentagastrin and the putative gastrin antagonist proglumide on interdigestive motility of the upper small bowel were studied in a randomised double blind study in 10 healthy human volunteers. Intraluminal pressures were recorded manometrically in the duodenum and jejunum for five hours. Sixty minutes af...

journal_title：Gut

authors： Erckenbrecht JF,Caspari J,Wienbeck M

更新日期：1984-09-01 00:00:00

abstract：:Peptide histidine isoleucine, a 27 amino acid peptide with close amino acid sequence homology to vasoactive intestinal peptide and secretin, is distributed throughout the mammalian intestinal tract, where it has been localised to intramural neurones. An intestinal perfusion technique has been used to study the effect ...

journal_title：Gut

authors： Moriarty KJ,Hegarty JE,Tatemoto K,Mutt V,Christofides ND,Bloom SR,Wood JR

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:Chronic pancreatitis is a progressive inflammatory disorder of the pancreas characterised by permanent destruction of acinar cells. Mutations in the chymotrypsinogen C (CTRC) gene have been linked to the development of chronic pancreatitis. The aim of the present study was to explore whether CTRC mutants indu...

journal_title：Gut

authors： Szmola R,Sahin-Tóth M

更新日期：2010-03-01 00:00:00

abstract：:The variability in the orocaecal transit time as measured by the lactulose/breath hydrogen method has been studied for three conditions: lactulose given with a meal, subjects sitting; lactulose given with a meal, subjects semirecumbent; lactulose given in aqueous solution, subjects semirecumbent. Thirty three healthy ...

journal_title：Gut

authors： Staniforth DH,Rose D

更新日期：1989-02-01 00:00:00