Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes.

abstract：:The typical macroscopic features of Crohn's disease have been well described and are widely regarded as sufficient to diagnose the disease at laparotomy. We report six patients undergoing laparotomy for symptomatic Crohn's disease, shown radiologically, who were found to have macroscopically normal small bowel despite...

journal_title：Gut

authors： Butterworth RJ,Williams GT,Hughes LE

更新日期：1992-01-01 00:00:00

abstract：:Training to contract the abdominal muscles effectively and to relax the pelvic floor during defecation straining helps some patients with severe constipation. Hitherto all such training has used a visible or audible signal of sphincter muscle activity as a biofeedback method to assist in relaxation. A randomised contr...

journal_title：Gut

authors： Koutsomanis D,Lennard-Jones JE,Roy AJ,Kamm MA

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:In association with innate and adaptive immunity, the microbiota controls the colonisation resistance against intestinal pathogens. Caspase recruitment domain 9 (CARD9), a key innate immunity gene, is required to shape a normal gut microbiota. Card9-/- mice are more susceptible to the enteric mouse pathogen C...

journal_title：Gut

authors： Lamas B,Michel ML,Waldschmitt N,Pham HP,Zacharioudaki V,Dupraz L,Delacre M,Natividad JM,Costa GD,Planchais J,Sovran B,Bridonneau C,Six A,Langella P,Richard ML,Chamaillard M,Sokol H

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Genetic haemochromatosis is a common hereditary iron loading disorder in humans. The disease is associated with loss of function mutations in the HFE gene. This is thought to change iron stores via increased iron absorption. AIMS:In this study we investigated how adaptation of mucosal reductase activity is ...

journal_title：Gut

authors： Simpson RJ,Debnam E,Beaumont N,Bahram S,Schümann K,Srai SK

更新日期：2003-04-01 00:00:00

abstract：:This study reports on a group of 20 patients with an initial diagnosis of primary biliary cirrhosis (PBC) whose serum tested negative for antimitochondrial antibodies by immunofluorescence. All had a clinical history compatible with primary biliary cirrhosis, and results of biochemical, histological, and radiological ...

journal_title：Gut

authors： Michieletti P,Wanless IR,Katz A,Scheuer PJ,Yeaman SJ,Bassendine MF,Palmer JM,Heathcote EJ

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:Hepatocellular carcinoma (HCC) is a prevalent and aggressive cancer usually arising on a background of chronic liver injury involving inflammatory and hepatic regenerative processes. The triggering receptor expressed on myeloid cells 2 (TREM-2) is predominantly expressed in hepatic non-parenchymal cells and i...

journal_title：Gut

authors： Esparza-Baquer A,Labiano I,Sharif O,Agirre-Lizaso A,Oakley F,Rodrigues PM,Zhuravleva E,O'Rourke CJ,Hijona E,Jimenez-Agüero R,Riaño I,Landa A,La Casta A,Zaki MYW,Munoz-Garrido P,Azkargorta M,Elortza F,Vogel A,Schabbaue

更新日期：2020-09-09 00:00:00

abstract：BACKGROUND AND AIM:Accumulation and infiltration by neutrophil granulocytes is a prominent feature in the local inflammatory process in ulcerative colitis (UC). The present study was performed to evaluate human neutrophil lipocalin (HNL) as a specific neutrophil marker in the inflamed lesions of the colon and rectum in...

journal_title：Gut

authors： Carlson M,Raab Y,Sevéus L,Xu S,Hällgren R,Venge P

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Helicobacter pylori (H pylori) infection is a major risk factor in the development of distal gastric adenocarcinoma. Development of the invasive phenotype is associated with the phenomenon of epithelial:mesenchymal transition (EMT). Soluble heparin-binding epidermal growth factor (HB-EGF) has been i...

journal_title：Gut

authors： Yin Y,Grabowska AM,Clarke PA,Whelband E,Robinson K,Argent RH,Tobias A,Kumari R,Atherton JC,Watson SA

更新日期：2010-08-01 00:00:00

abstract：:Human cholera is associated with an increased luminal release of prostaglandin E2 (PGE2), but whether inhibition of increased PGE2 synthesis will reduce or control intestinal secretion is uncertain. 'Steady state' perfusions (10 ml/minute) in 12 patients with acute cholera, and repeat perfusions in nine of these patie...

journal_title：Gut

authors： Van Loon FP,Rabbani GH,Bukhave K,Rask-Madsen J

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Patients with chronic hepatitis B (CHB) infection are at an increased risk of developing hepatocellular carcinoma (HCC). Risk scores have been developed in Asian populations to predict HCC risk over time. AIM:To assess the performance of HCC risk prediction models in a heterogeneous population of patients w...

journal_title：Gut

authors： Abu-Amara M,Cerocchi O,Malhi G,Sharma S,Yim C,Shah H,Wong DK,Janssen HL,Feld JJ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:There is a widespread notion that obesity leads to gastro-oesophageal reflux but scientific evidence of an association is limited and inconsistent. AIMS:To estimate the strength of the association between body mass and reflux symptoms, we performed a population based cross sectional interview study. SUBJEC...

journal_title：Gut

authors： Lagergren J,Bergström R,Nyrén O

更新日期：2000-07-01 00:00:00

abstract：:The influence of dehydrocholate on bromsulphtalein relative-storage capacity, bilary transport maximum (Tm), and fractional transfer rates between plasma, liver and bile have been studied in unanaesthetized dogs. In six dogs, storage capacity, Tm, and fractional transfer rates from plasma to liver, liver to bile, and ...

journal_title：Gut

authors： Delage Y,Erlinger S,Duval M,Bpenhamou JP

更新日期：1975-02-01 00:00:00

abstract：OBJECTIVES:Many patients with Crohn's disease (CD) have low bone mineral density (BMD) that may not be solely attributable to glucocorticoid use. We hypothesised that low BMD in patients with CD is associated with elevated circulating levels of the active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)(2)D). We fu...

journal_title：Gut

authors： Abreu MT,Kantorovich V,Vasiliauskas EA,Gruntmanis U,Matuk R,Daigle K,Chen S,Zehnder D,Lin YC,Yang H,Hewison M,Adams JS

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Treatment of Helicobacter pylori infection prevents duodenal ulcer relapse. It has not been established if treatment of the infection heals duodenal ulcer. AIM:To test the hypothesis that treatment of the infection was associated with healing of duodenal ulcer. METHODS:A randomised, double blind placebo co...

journal_title：Gut

authors： Lam SK,Ching CK,Lai KC,Wong BC,Lai CL,Chan CK,Ong L

更新日期：1997-07-01 00:00:00

abstract：:Peptide histidine isoleucine, a 27 amino acid peptide with close amino acid sequence homology to vasoactive intestinal peptide and secretin, is distributed throughout the mammalian intestinal tract, where it has been localised to intramural neurones. An intestinal perfusion technique has been used to study the effect ...

journal_title：Gut

authors： Moriarty KJ,Hegarty JE,Tatemoto K,Mutt V,Christofides ND,Bloom SR,Wood JR

更新日期：1984-06-01 00:00:00

abstract：:Polyacrylamide gel electrophoresis of pure pancreatic juice from 14 healthy normal subjects, 11 chronic alcoholics without detectable pancreatic disease, 15 patients with pancreatitis, and two with cancer of the pancreas consistently demonstrated the presence of two variants of trypsinogen with different electrophoret...

journal_title：Gut

authors： Rinderknecht H,Renner IG,Carmack C

更新日期：1979-10-01 00:00:00

abstract：OBJECTIVE:Reports on the effects of bone marrow-derived cells on hepatic fibrosis are contradictory. Impaired fibrosis but increased inflammation has recently been demonstrated 10 weeks after bone marrow transplantation (BM-Tx) in Abcb4-/- mice. It is hypothesised that BM-Tx might have long-term therapeutic potential b...

journal_title：Gut

authors： Roderfeld M,Rath T,Pasupuleti S,Zimmermann M,Neumann C,Churin Y,Dierkes C,Voswinckel R,Barth PJ,Zahner D,Graf J,Roeb E

更新日期：2012-06-01 00:00:00

abstract：:The effects of the methyl ester analogue of prostaglandin E1, misoprostol, on gastric epithelial cell proliferation were investigated in six dogs given 300 micrograms/kg/day of misoprostol orally for 11 weeks and in six control dogs given placebo for 11 weeks. Misoprostol treatment resulted in a 36% increase in stomac...

journal_title：Gut

authors： Goodlad RA,Madgwick AJ,Moffatt MR,Levin S,Allen JL,Wright NA

更新日期：1989-03-01 00:00:00

abstract：:Twenty one patients with diabetic peripheral neuropathy, 18 with idiopathic faecal incontinence and 11 normal controls were studied with techniques of mucosal electrosensitivity, rectal distension for the quantitative assessment of anorectal sensation, and manometric and electromyographic tests for the assessment of a...

journal_title：Gut

authors： Rogers J,Levy DM,Henry MM,Misiewicz JJ

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Data on genetic susceptibility to sporadic gastric carcinoma have been published at a growing pace, but to date no comprehensive overview and quantitative summary has been available. METHODS:We conducted a systematic review and meta-analysis of the evidence on the association between DNA variation and risk ...

journal_title：Gut

authors： Mocellin S,Verdi D,Pooley KA,Nitti D

更新日期：2015-08-01 00:00:00

abstract：:The risk of developing colorectal adenomatous polyps is probably increased by a variety of dietary and environmental factors. We found an association with current alcohol and cigarette consumption. The risk of polyps was increased three times in drinkers who did not smoke and two times in smokers who did not drink, wi...

journal_title：Gut

authors： Cope GF,Wyatt JI,Pinder IF,Lee PN,Heatley RV,Kelleher J

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:Chronic gastro-oesophageal reflux might lead to the development of Barrett's oesophagus (BO) or even oesophageal adenocarcinoma. There has been no definitive systematic review and meta-analysis of data to estimate global prevalence of BO or oesophageal adenocarcinoma in individuals with gastro-oesophageal re...

journal_title：Gut

authors： Eusebi LH,Cirota GG,Zagari RM,Ford AC

更新日期：2020-07-30 00:00:00

abstract：:Synthetic 13-norleucine-motilin (13-nle-motilin), structural and biological analogue of the naturally-occurring duodenal polypeptide, motilin, is known to stimulate antral and duodenal motor activity in vitro, but delays gastric emptying in man. In this study the direct actions of the synthetic polypeptide on myoelect...

journal_title：Gut

authors： Green WE,Ruppin H,Wingate DL,Domschke W,Wünsch DE,Demling L,Ritchie HD

更新日期：1976-05-01 00:00:00

abstract：OBJECTIVE:Early detection and early treatment are of vital importance to the successful treatment of various cancers. The development of a novel screening method that is as economical and non-invasive as the faecal occult blood test (FOBT) for early detection of colorectal cancer (CRC) is needed. A study was undertaken...

journal_title：Gut

authors： Sonoda H,Kohnoe S,Yamazato T,Satoh Y,Morizono G,Shikata K,Morita M,Watanabe A,Morita M,Kakeji Y,Inoue F,Maehara Y

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Osteoporosis and fractures are frequently encountered in patients with Crohn's disease. In order to prevent fractures, treatment with bone protecting drugs appears warranted early in the course of bone disease when bone loss is not yet prominent. We therefore aimed to demonstrate a beneficial effect on bone d...

journal_title：Gut

authors： van Bodegraven AA,Bravenboer N,Witte BI,Dijkstra G,van der Woude CJ,Stokkers PC,Russel MG,Oldenburg B,Pierik M,Roos JC,van Hogezand RA,Dik VK,Oostlander AE,Netelenbos JC,van de Langerijt L,Hommes DW,Lips P,Dutch Initiat

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:An increasing number of patients with severe or refractory ulcerative colitis involving only the rectum and sigmoid colon are being offered restorative proctocolectomy with ileal reservoir but very few data are available concerning the outcome for these patients. AIM:This study was designed to compare the o...

journal_title：Gut

authors： Samarasekera DN,Stebbing JF,Kettlewell MG,Jewell DP,Mortensen NJ

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The relation of demographic and psychological factors to the presence and extent of gut transit impairment in the functional gastrointestinal disorders has received little attention. AIMS:To compare the psychosocial and demographic features of patients with functional gastrointestinal disorders and delayed ...

journal_title：Gut

authors： Bennett EJ,Evans P,Scott AM,Badcock CA,Shuter B,Höschl R,Tennant CC,Kellow JE

更新日期：2000-01-01 00:00:00

abstract：:Lymphangiomas are rare tumours of lymphatic vessels, most commonly found in children. We present the unusual case of small bowel obstruction caused by benign lymphangioma in a middle aged woman. ...

journal_title：Gut

authors： Campbell WJ,Irwin ST,Biggart JD

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Insulin resistance is a frequent feature of chronic hepatitis C. Whether insulin resistance could be the cause or consequence of steatosis and fibrosis is unknown. The ability of HCV genotype 3 to promote steatosis by itself provides an unique opportunity to answer this question. AIMS:The aim of the present...

journal_title：Gut

authors： Fartoux L,Poujol-Robert A,Guéchot J,Wendum D,Poupon R,Serfaty L

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:The intestinal microbiome affects the prevalence and pathophysiology of a variety of diseases ranging from inflammation to cancer. A reduced taxonomic or functional diversity of the microbiome was often observed in association with poorer health outcomes or disease in general. Conversely, factors or manifest ...

journal_title：Gut

authors： Frost F,Kacprowski T,Rühlemann M,Pietzner M,Bang C,Franke A,Nauck M,Völker U,Völzke H,Dörr M,Baumbach J,Sendler M,Schulz C,Mayerle J,Weiss FU,Homuth G,Lerch MM

更新日期：2020-11-09 00:00:00