Outcome of restorative proctocolectomy with ileal reservoir for ulcerative colitis: comparison of distal colitis with more proximal disease.

abstract：OBJECTIVE:Caffeine reduces toxic Ca2+ signals in pancreatic acinar cells via inhibition of inositol 1,4,5-trisphosphate receptor (IP3R)-mediated signalling, but effects of other xanthines have not been evaluated, nor effects of xanthines on experimental acute pancreatitis (AP). We have determined effects of caffeine an...

journal_title：Gut

authors： Huang W,Cane MC,Mukherjee R,Szatmary P,Zhang X,Elliott V,Ouyang Y,Chvanov M,Latawiec D,Wen L,Booth DM,Haynes AC,Petersen OH,Tepikin AV,Criddle DN,Sutton R

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Patients with liver cirrhosis are at increased risk of serious bacterial infections carrying a high case fatality rate. Case reports have suggested an association between liver cirrhosis and pyogenic liver abscess. AIMS:To estimate the risk and case fatality rate of pyogenic liver abscess in Danish patients...

journal_title：Gut

authors： Mølle I,Thulstrup AM,Vilstrup H,Sørensen HT

更新日期：2001-02-01 00:00:00

abstract：:Intragastric total bile acid concentrations were measured before and after a corn oil test meal in 16 patients with erosive oesophagitis and symptoms of gastro-oesophageal reflux. Sixteen age and sex matched control subjects were also studied. No significant difference was detected between fasting or postprandial gast...

journal_title：Gut

authors： Collins BJ,Crothers G,McFarland RJ,Love AH

更新日期：1985-05-01 00:00:00

abstract：:To determine whether primary biliary cirrhosis differed in men and women we reviewed the presenting features and clinical course of 39 men and 191 women with primary biliary cirrhosis followed at this unit between 1970 and 1984. Age and severity of disease at time of diagnosis were similar in both groups. Pruritus was...

journal_title：Gut

authors： Lucey MR,Neuberger JM,Williams R

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Major histocompatibility complex class II deficient (Aalpha0/0) mice have decreased CD4+ T cells, making them immunologically similar to patients with acquired immunodeficiency syndrome (AIDS). Both patients with AIDS and Aalpha0/0 mice have hypertrophic gastric folds. To clarify the mechanism of ga...

journal_title：Gut

authors： Fukui T,Nishio A,Okazaki K,Uza N,Ueno S,Kido M,Inoue S,Kitamura H,Kiriya K,Ohashi S,Asada M,Tamaki H,Matsuura M,Kawasaki K,Suzuki K,Uchida K,Fukui H,Nakase H,Watanabe N,Chiba T

更新日期：2006-05-01 00:00:00

abstract：:In a randomised clinical trial, patients with moderately active Crohn's disease received either prednisolone 0.5 mg/kg/day plus a normal diet, or an elemental diet plus oral framycetin, colistin and nystatin. Patients were assessed using the Crohn's disease activity index (CDAI), ESR, and faecal granulocyte excretion ...

journal_title：Gut

authors： Saverymuttu S,Hodgson HJ,Chadwick VS

更新日期：1985-10-01 00:00:00

abstract：:The effect of the unconjugated bile acids, cholic, deoxycholic, chenodeoxycholic, and ursodeoxycholic acids, and of the conjugated bile acid taurocholic acid on the mucosal-to-serosal transport and tissue uptake of the naturally occurring folate derivative, 5-methyltetrahydrofolate (5-CH3H4PteGlu) was examined in ever...

journal_title：Gut

authors： Said HM,Hollander D,Strum WB

更新日期：1984-12-01 00:00:00

abstract：:All patients presenting with acute upper gastrointestinal bleeding between November 1986 and April 1988 were admitted to a centralised joint medical/surgical unit, with a policy of early clinical and endoscopic assessment and rapid surgical intervention in those at high risk. Of the 430 patients admitted 69.5% were ov...

journal_title：Gut

authors： Holman RA,Davis M,Gough KR,Gartell P,Britton DC,Smith RB

更新日期：1990-05-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) levels have been measured in the serum of 490 patients and 93 normal controls using the double antibody radioimmunoassay technique. Levels were elevated in 71 of patients with carcinomata of the gastrointestinal tract and in 42% with other types of malignancy. In patients with non-neopla...

journal_title：Gut

authors： Booth SN,King JP,Leonard JC,Dykes PW

更新日期：1973-10-01 00:00:00

abstract：:Serum gastrin levels have been studied in 70 patients with chronically reduced glomerular filtration rate (GFR) as estimated by 51Cr-EDTA clearance, creatinine, and beta2-microglobulin values. A strong dependence upon GFR was found, although the correlation between gastrin levels and GFR was not as high as that betwee...

journal_title：Gut

authors： Hällgren R,Karlsson FA,Lundqvist G

更新日期：1978-03-01 00:00:00

abstract：:Previous studies have shown that ileal infusion of partially digested triglyceride inhibits jejunal motility. The partial digest used in those studies contained a mixture of glycerol, free fatty acid, mono-, di-, and triglycerides. In Part I of the present study we have separately infused emulsions containing either g...

journal_title：Gut

authors： Spiller RC,Trotman IF,Adrian TE,Bloom SR,Misiewicz JJ,Silk DB

更新日期：1988-08-01 00:00:00

abstract：:Four different dosage regimens of interferon (IFN) alfa-2b (3 million units (MU) three times weekly for three months, 3 MU three times weekly for six months, 6 MU two times weekly for six months, and 6 MU three times weekly for six months) were compared in patients with chronic hepatitis C. There was no significant di...

journal_title：Gut

authors： De Bac C,Grimaldi F,Clementi C,Duca F,Livoli D,Taliani G

更新日期：1993-01-01 00:00:00

abstract：:The ability to digest mucus, mucolytic activity of isolated pepsins and samples of human gastric juice has been assayed by measuring the fall in viscosity when incubated with purified pig gastric mucus glycoprotein. Pure human pepsin 1, the peptic ulcer associated pepsin, digested gastric mucus glycoprotein at a faste...

journal_title：Gut

authors： Pearson JP,Ward R,Allen A,Roberts NB,Taylor WH

更新日期：1986-03-01 00:00:00

abstract：:The plasma clearance and the liver uptake of intravenously administered (64)Cu were significantly impaired in four patients with Wilson's disease. These defects were unlikely to be simply expressions of the high liver copper concentration as the plasma clearance and hepatic uptake of (64)Cu were normal in four patient...

journal_title：Gut

authors： Smallwood RA,McIlveen B,Rosenoer VM,Sherlock S

更新日期：1971-02-01 00:00:00

abstract：BACKGROUND:Recent profile studies of microRNA (miRNA) expression have documented a deregulation of miRNA (miR-124) in hepatocellular carcinoma (HCC). OBJECTIVE:To determine the status of miR-124 expression and its underlying mechanisms in the pathogenesis of HCC. METHODS:The expression levels of miR-124 were first ex...

journal_title：Gut

authors： Zheng F,Liao YJ,Cai MY,Liu YH,Liu TH,Chen SP,Bian XW,Guan XY,Lin MC,Zeng YX,Kung HF,Xie D

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:In some infants with liver disease, 3-oxo-delta 4 bile acids are the major bile acids in urine, a phenomenon attributed to reduced activity of the delta 4-3-oxosteroid 5 beta-reductase required for synthesis of chenodeoxycholic acid and cholic acid. These patients form a heterogeneous group. Many have a know...

journal_title：Gut

authors： Clayton PT,Mills KA,Johnson AW,Barabino A,Marazzi MG

更新日期：1996-04-01 00:00:00

abstract：:Gastric adaptation was impaired immediately after the performance of complete vagotomy in a series of 20 acute experiments in the dog. Preliminary isolation of the intact vagi in 10 of these animals produced alterations in adaptation similar to those seen after vagal division. It is concluded that alterations in gastr...

journal_title：Gut

authors： Carter DC,Whitfield HN,Macleod IB

更新日期：1972-11-01 00:00:00

abstract：:Introduction of a radioactive gastrointestinal marker (51CrCl3) into a combined study (75SeHCAT + 58CoB12) of ileal function by whole body counting has been undertaken. The technique was assessed in 23 subjects (15 patients with inflammatory bowel disease, six on non-steroidal anti-inflammatory drugs for rheumatoid ar...

journal_title：Gut

authors： Smith T,Bjarnason I

更新日期：1990-10-01 00:00:00

abstract：:A histological study of peroral jejunal biopsies and resection specimens from patients with malignant histiocytosis of the intestine (MHI) has revealed characteristic lesions consisting of intramucosal histiocytic aggregations which invade surface and crypt epithelium. These lesions are found in 'uninvolved' jejunal m...

journal_title：Gut

authors： Isaacson P

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Increased serum antibodies against carbonic anhydrase II (CA-II Ab) or IgG4 levels have been reported in cases of autoimmune chronic pancreatitis (ACP). AIM:To assess the relevance of serum CA-II Ab and IgG4 levels for the diagnosis of ACP in idiopathic CP (ICP) versus alcoholic CP and Sjogren's syndrome (S...

journal_title：Gut

authors： Aparisi L,Farre A,Gomez-Cambronero L,Martinez J,De Las Heras G,Corts J,Navarro S,Mora J,Lopez-Hoyos M,Sabater L,Ferrandez A,Bautista D,Perez-Mateo M,Mery S,Sastre J

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, may play a critical role in many chronic pain conditions. The possible involvement of BDNF in the altered gut sensation in patients with irritable bowel syndrome (IBS) was investigated in the present study. METHODS:Rectosigmoid bi...

journal_title：Gut

authors： Yu YB,Zuo XL,Zhao QJ,Chen FX,Yang J,Dong YY,Wang P,Li YQ

更新日期：2012-05-01 00:00:00

abstract：:Although a high prevalence of antibodies to Helicobacter pylori has been documented within families, culture and DNA typing of strains from infected children and their parents has not been evaluated. This study aimed to analyse H pylori infection within family groups. Endoscopy, gastric biopsy, and H pylori culture we...

journal_title：Gut

authors： Bamford KB,Bickley J,Collins JS,Johnston BT,Potts S,Boston V,Owen RJ,Sloan JM

更新日期：1993-10-01 00:00:00

abstract：CLINICAL PRESENTATION:A 28-year-old woman presented with a 3-year history of chronic watery diarrhoea along with abdominal pain and bloating, which could mostly be alleviated after defecation. Her symptom of diarrhoea, at least three times a day, could be relieved by neither probiotics nor antidiarrhoeal agents. She ha...

journal_title：Gut

authors： Zhou CB,Lu H,Chen YX,Fang JY

更新日期：2019-03-01 00:00:00

abstract：:Big differences in the prevalence of peptic ulcer are known to exist in different parts of India. This paper reports a high incidence in Assam and records certain differences with peptic ulcers found in south India. ...

journal_title：Gut

authors： MALHOTRA SL,MAJUMDAR CT,BARDOLOI PC

更新日期：1964-08-01 00:00:00

abstract：:Visceral hypersensitivity has been recognised as a characteristic of patients with irritable bowel syndrome (IBS). It may be involved in the pathogenesis of abdominal pain/discomfort, and seems to result from the sensitisation of nerve afferent pathways originating from the gastrointestinal tract. From a clinical poin...

journal_title：Gut

authors： Delvaux M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND AIM:To clarify the roles of Helicobacter pylori cytotoxin in gastric atrophy, the cytotoxin positive rate and cytotoxin activity in Fukui and Okinawa, where the prevalence of atrophic gastritis and gastric cancer risk are quite different, were studied. MATERIALS:Seventy three strains from Fukui and 51 f...

journal_title：Gut

authors： Ito S,Azuma T,Murakita H,Hirai M,Miyaji H,Ito Y,Ohtaki Y,Yamazaki Y,Kuriyama M,Keida Y,Kohli Y

更新日期：1996-12-01 00:00:00

abstract：:Synchronous cancers of the oesophagus and stomach diagnosed in a patient showing pronounced leucocytosis were examined for production of granulocyte colony stimulating factor (G-CSF) and expression of G-CSF receptor. Whereas enzyme immunoassay of tissue extracts showed that the oesophageal carcinoma produced G-CSF, th...

journal_title：Gut

authors： Ichiishi E,Yoshikawa T,Kogawa T,Yoshida N,Kondo M

更新日期：2000-03-01 00:00:00

abstract：AIM:Magnetic resonance imaging (MRI) based colonography represents a new imaging tool which has mainly been investigated for polyp screening. To evaluate this approach for patients with inflammatory bowel disease (IBD), we compared MRI based colonography with conventional colonoscopy for assessing the presence and exte...

journal_title：Gut

authors： Schreyer AG,Rath HC,Kikinis R,Völk M,Schölmerich J,Feuerbach S,Rogler G,Seitz J,Herfarth H

更新日期：2005-02-01 00:00:00

abstract：:Glycosylation is a key modification of proteins and lipids and is involved in most intermolecular and intercellular interactions. The gastrointestinal mucus gel is continuous and can be divided into two layers: a secreted loosely associated layer and a layer firmly attached to the mucosa. In addition, the membrane-bou...

journal_title：Gut

authors： Moran AP,Gupta A,Joshi L

更新日期：2011-10-01 00:00:00

abstract：:The distribution of mucosal PGE2-like activity was determined by bioassay technique in the body and antrum of the stomach and in the duodenum of healthy subjects and duodenal ulcer patients before and after administration of aspirin, paracetamol, or histamine. In healthy subjects, the oxyntic, antral and duodenal muco...

journal_title：Gut

authors： Konturek SJ,Obtulowicz W,Sito E,Oleksy J,Wilkon S,Kiec-Dembinska A

更新日期：1981-04-01 00:00:00