Serum carcinoembryonic antigen in clinical disorders.

abstract：BACKGROUND:Increased serum antibodies against carbonic anhydrase II (CA-II Ab) or IgG4 levels have been reported in cases of autoimmune chronic pancreatitis (ACP). AIM:To assess the relevance of serum CA-II Ab and IgG4 levels for the diagnosis of ACP in idiopathic CP (ICP) versus alcoholic CP and Sjogren's syndrome (S...

journal_title：Gut

authors： Aparisi L,Farre A,Gomez-Cambronero L,Martinez J,De Las Heras G,Corts J,Navarro S,Mora J,Lopez-Hoyos M,Sabater L,Ferrandez A,Bautista D,Perez-Mateo M,Mery S,Sastre J

更新日期：2005-05-01 00:00:00

abstract：:Oral treatment with chenodeoxycholic acid causes dissolution of cholesterol gallstones in man. In order to determine the mechanism of this effect, we have measured 24-hour biliary lipid output, lipid composition of fasting gallbladder bile, and bile acid pool sizes before and during such treatment in six patients with...

journal_title：Gut

authors： Northfield TC,LaRusso NF,Hofmann AF,Thistle JL

更新日期：1975-01-01 00:00:00

abstract：:To examine socioeconomic factors, dietary and other personal habits, and medical history as risk factors for ulcerative colitis, we studied 167 (98%) of all prevalent cases of ulcerative colitis diagnosed in Uppsala county from 1945 to 1964 and 167 age and sex matched population controls. Ulcerative colitis patients w...

journal_title：Gut

authors： Samuelsson SM,Ekbom A,Zack M,Helmick CG,Adami HO

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:The long-term performance of colorectal cancer (CRC) screening programmes based on a 2-year faecal immunochemical test (FIT) is still unclear. METHODS:In a sample of 50 to 69-year-olds repeatedly screened with the FIT (OC-Hemodia latex agglutination test; cut-off: 20 µg haemoglobin/g faeces), we examined: (...

journal_title：Gut

authors： Zorzi M,Hassan C,Capodaglio G,Fedato C,Montaguti A,Turrin A,Rosano A,Monetti D,Stocco C,Baracco S,Russo F,Repici A,Rugge M

更新日期：2018-12-01 00:00:00

abstract：:The effects of low power (1-2 Watts), long exposure (30-400 seconds), interstitial Nd YAG laser therapy on dimethylhydrazine induced rat colonic neoplasms and normal rat colon have been studied. After a single exposure with appropriate laser parameters, dimethylhydrazine induced rat colonic neoplasms underwent coagula...

journal_title：Gut

authors： Matthewson K,Barton T,Lewin MR,O'Sullivan JP,Northfield TC,Bown SG

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Osteopontin (OPN) has been found to be valuable in diagnosis and predicting the prognosis of a variety of malignancies. The aims of the present study are to evaluate the usefulness of plasma OPN level for predicting gastric cancer development, invasion and survival. PATIENTS AND METHODS:One hundred and thirt...

journal_title：Gut

authors： Wu CY,Wu MS,Chiang EP,Wu CC,Chen YJ,Chen CJ,Chi NH,Chen GH,Lin JT

更新日期：2007-06-01 00:00:00

abstract：AIMS:To determine the sources of founding for UK gastroenterology research papers and the relative impact of papers funded by different groups and of unfunded ones. METHODS:UK gastroenterology papers from 1988-94 were selectively retrieved from the Science Citation Index by means of a specially constructed filter base...

journal_title：Gut

authors： Lewison G

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:The transcriptional profile of gastric epithelial cell lines cocultured with Helicobacter pylori and the global gene expression of whole gastric mucosa has been described previously. We aimed to overcome limitations of previous studies by determining the effects of H pylori eradication on the transcriptome of...

journal_title：Gut

authors： Resnick MB,Sabo E,Meitner PA,Kim SS,Cho Y,Kim HK,Tavares R,Moss SF

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Intraluminal acid evokes reflex contraction of oesophageal longitudinal smooth muscle (LSM) and consequent oesophageal shortening. This reflex may play a role in the pathophysiology of oesophageal pain syndromes and hiatus hernia formation. The aim of the current study was to elucidate further the mechanisms ...

journal_title：Gut

authors： Paterson WG,Miller DV,Dilworth N,Assini JB,Lourenssen S,Blennerhassett MG

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:A rapid, reliable, and accurate test for the diagnosis of infection with Helicobacter pylori is needed for screening dyspeptic patients before referral for endoscopy. AIM:To compare a new rapid whole blood test (Helisal rapid blood, Cortecs), two serum enzyme linked immunosorbent assays (ELISAs; Helico-G, S...

journal_title：Gut

authors： Reilly TG,Poxon V,Sanders DS,Elliott TS,Walt RP

更新日期：1997-04-01 00:00:00

abstract：:To determine the optimum dose of ispaghula husk in patients with irritable bowel syndrome (IBS) and to assess the correlation, if any between the relief in patients' symptoms and the whole gut transit time, and the increase in stool weight, a two part study was carried out. In part 1, 14 male patients were given ispag...

journal_title：Gut

authors： Kumar A,Kumar N,Vij JC,Sarin SK,Anand BS

更新日期：1987-02-01 00:00:00

abstract：AIM:Magnetic resonance imaging (MRI) based colonography represents a new imaging tool which has mainly been investigated for polyp screening. To evaluate this approach for patients with inflammatory bowel disease (IBD), we compared MRI based colonography with conventional colonoscopy for assessing the presence and exte...

journal_title：Gut

authors： Schreyer AG,Rath HC,Kikinis R,Völk M,Schölmerich J,Feuerbach S,Rogler G,Seitz J,Herfarth H

更新日期：2005-02-01 00:00:00

abstract：:Seven patients with hypoalbuminaemia and extensive jejunoileal Crohn's disease were treated with an elemental diet for 28 to 56 days. Over this time there was an increase in total plasma proteins from mean of 49.1 to 59.0 g/l and a mean rise in serum albumin from 20.7 to 30.0 g/l (P less than 0.05). In addition, there...

journal_title：Gut

authors： Logan RF,Gillon J,Ferrington C,Ferguson A

更新日期：1981-05-01 00:00:00

abstract：:The distribution of mucosal PGE2-like activity was determined by bioassay technique in the body and antrum of the stomach and in the duodenum of healthy subjects and duodenal ulcer patients before and after administration of aspirin, paracetamol, or histamine. In healthy subjects, the oxyntic, antral and duodenal muco...

journal_title：Gut

authors： Konturek SJ,Obtulowicz W,Sito E,Oleksy J,Wilkon S,Kiec-Dembinska A

更新日期：1981-04-01 00:00:00

abstract：OBJECTIVES:The postinfectious irritable bowel syndrome (PI-IBS) suggests that impaired resolution of inflammation could cause IBS symptoms. The authors hypothesised that polymorphisms in genes whose expression were altered by gastroenteritis might be linked to IBS with diarrhoea (IBS-D) which closely resembles PI-IBS. ...

journal_title：Gut

authors： Swan C,Duroudier NP,Campbell E,Zaitoun A,Hastings M,Dukes GE,Cox J,Kelly FM,Wilde J,Lennon MG,Neal KR,Whorwell PJ,Hall IP,Spiller RC

更新日期：2013-07-01 00:00:00

abstract：:Over 90% of patients with inoperable carcinoma of the pancreas are successfully palliated by endoscopic retrograde cholangiopancreatography and stent insertion. Treatment of the residual 10% of patients often entails a laparotomy, which is difficult to justify when median survival of these patients is only 150 days. L...

journal_title：Gut

authors： Rhodes M,Nathanson L,Fielding G

更新日期：1995-05-01 00:00:00

abstract：:In two patients presenting with mild intestinal symptoms, rectal spirochaetosis was the only morphological abnormality diagnosed by light microscopy. A re-evaluation of the morphological changes using electron microscopy and immunohistochemistry showed certain unusual features: the microorganisms were observed within ...

journal_title：Gut

authors： Gebbers JO,Ferguson DJ,Mason C,Kelly P,Jewell DP

更新日期：1987-05-01 00:00:00

abstract：:A man with long-standing pernicious anaemia developed multiple gastric carcinoid tumours with a background of diffuse enterochromaffin-like cell hyperplasia. There is evidence that enterochromaffin-like cells synthesis and store histamine and that their proliferation is stimulated by high serum gastrin levels. Gastric...

journal_title：Gut

authors： Hodges JR,Isaacson P,Wright R

更新日期：1981-03-01 00:00:00

abstract：:This paper describes opacification and identification of two surgically constructed pancreatico-jujunal shunts. A fibreoptic panendoscope was used with retrograde injection via the ampulla of Vater (ERCP). This procedure makes possible more accurate anatomical evaluation and so more precise clinical appraisal of both...

journal_title：Gut

authors： Miller EW,Goldberg HI,Goldberg SB,Shapiro H

更新日期：1976-06-01 00:00:00

abstract：:All cases of Crohn's disease in the Nottingham area were ascertained and the date and place of domicile and work at the time of onset of symptoms noted. Applying the Knox and Pike and Smith tests for clustering of patients in time and space, no significant results were observed. Further analysis of differences in time...

journal_title：Gut

authors： Miller DS,Keighley A,Smith PG,Hughes AO,Langman MJ

更新日期：1975-06-01 00:00:00

abstract：:4-Aminosalicylic acid (4-ASA) has been suggested as an effective treatment for both active and quiescent ulcerative colitis. 5-Aminosalicylic acid (5-ASA) is well accepted for the maintenance treatment of inactive ulcerative colitis. Moreover, recent studies suggest that 5-ASA may also be effective in maintaining remi...

journal_title：Gut

authors： Schreiber S,Howaldt S,Raedler A

更新日期：1994-08-01 00:00:00

abstract：:To study the mechanism for the adaptive mucosal hyperplasia which occurs independent of luminal nutrition and pancreatico-biliary secretions in isolated Thiry-Vella segments of intestine from lactating rats, and to examine the effects of prolactin on small bowel mucosal structure in the rat, we used two models of expe...

journal_title：Gut

authors： Muller E,Dowling RH

更新日期：1981-07-01 00:00:00

abstract：:Recent reports have indicated a possible role for 111Indium leucocyte scintigraphy in the management of patients with acute inflammatory bowel disease. Our experience with this technique in 15 patients (nine with ulcerative colitis, six with Crohn's disease) is described. Perfect agreement was not obtained between sci...

journal_title：Gut

authors： Buxton-Thomas MS,Dickinson RJ,Maltby P,Hunter JO,Wraight EP

更新日期：1984-12-01 00:00:00

abstract：:Despite mass population screening and an incidence of EGC in Japan that is at least double that of the West, there seem to be no genuine differences in the clinicopathological features of the disease between the two regions. The macroscopic appearance, size, depth of invasion, frequency of lymph node invasion, and his...

journal_title：Gut

authors： Everett SM,Axon AT

更新日期：1997-08-01 00:00:00

abstract：:The effects of drugs which change the bile-salt-independent fraction of bile flow on Na(+)K(a+) and Mg(2+) activated ATPases were studied in membrane fractions rich in bile canaliculi. The administration of phenobarbital caused no induction of these enzymes which could explain the increased bile flow observed in the r...

journal_title：Gut

authors： Laperche Y,Launay A,Oudéa P

更新日期：1972-11-01 00:00:00

abstract：BACKGROUND:Diabetes has been associated with an increased risk of hepatocellular carcinoma (HCC) in studies of referred patients. This is the first population based case control study in the USA to examine this association while adjusting for other major risk factors related to HCC. METHODS:We used the Surveillance Ep...

journal_title：Gut

authors： Davila JA,Morgan RO,Shaib Y,McGlynn KA,El-Serag HB

更新日期：2005-04-01 00:00:00

abstract：:Heartburn is a common symptom affecting 21-44% of the adult population on a monthly basis. Oesophagitis is less common, affecting 2% of individuals. Epidemiological studies have shown that patients with gastro-oesophageal reflux disease (GORD) have similar incidence rates of Helicobacter pylori infection as do control...

journal_title：Gut

authors： McNamara D,O'Morain C

更新日期：1999-07-01 00:00:00

abstract：:A previous cohort study suggested that there might be an association between use of cimetidine and motor neurone disease. The Oxford Record Linkage Study was used to explore this hypothesis. In the analysis the presence of a peptic ulcer in patients after 1976 was taken as a proxy for cimetidine (and ranitidine) use. ...

journal_title：Gut

authors： Vessey MP,Goldacre MJ,Seagroatt V,Yeates D

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:The complex genetic aetiology underlying irritable bowel syndrome (IBS) needs to be assessed in large-scale genetic studies. Two independent IBS cohorts were genotyped to assess whether genetic variability in immune, neuronal and barrier integrity genes is associated with IBS. DESIGN:384 single nucleotide po...

journal_title：Gut

authors： Wouters MM,Lambrechts D,Knapp M,Cleynen I,Whorwell P,Agréus L,Dlugosz A,Schmidt PT,Halfvarson J,Simrén M,Ohlsson B,Karling P,Van Wanrooy S,Mondelaers S,Vermeire S,Lindberg G,Spiller R,Dukes G,D'Amato M,Boeckxstaens

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Overexpression of tissue plasminogen activator (t-PA) in pancreatic cancer cells promotes invasion and proliferation in vitro and tumour growth and angiogenesis in vivo. AIMS:To understand the mechanisms by which t-PA favours cancer progression, we analysed the surface membrane proteins responsible for bind...

journal_title：Gut

authors： Díaz VM,Hurtado M,Thomson TM,Reventós J,Paciucci R

更新日期：2004-07-01 00:00:00