Selective deficiency of pancreatic amylase.

Abstract:

:Two patients with specific pancreatic amylase deficiency are described. The greatly reduced pancreatic amylase activity was not due to an enzymatically inactive amylase molecule but to an almost complete absence of the molecule itself. The findings are of diagnostic importance as they show that low pancreatic amylase activity in serum or duodenal aspirates, or both, does not necessarily represent chronic exocrine pancreatic disease such as chronic pancreatitis, carcinoma of the pancreas, or cystic fibrosis but may be an isolated finding. In one of our patients a familial occurrence was shown, indicating a congenital deficiency.

journal_name

Gut

journal_title

Gut

authors

Sjölund K,Häggmark A,Ihse I,Skude G,Kärnström U,Wikander M

doi

10.1136/gut.32.5.546

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

546-8

issue

5

eissn

0017-5749

issn

1468-3288

journal_volume

32

pub_type

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