Non-steroidal anti-inflammatory drug (NSAID) therapy in patients with hypertension, cardiovascular, renal or gastrointestinal comorbidities: joint APAGE/APLAR/APSDE/APSH/APSN/PoA recommendations.

abstract：:Both carbachol (10(-4)-10(-3) mol/l) and cholecystokinin octapeptide (CCK-8) (10(-8)-10(-6) mol/l) significantly stimulated the release of pepsinogen from rabbit gastric mucosa maintained in organ culture (213-216% and 143-261% of control, respectively, p less than 0.05-0.01). The secretion was not affected by removin...

journal_title：Gut

authors： Miyamoto T,Itoh M,Noguchi Y,Yokochi K

更新日期：1992-01-01 00:00:00

abstract：:A method not needing fluoroscopic control for positioning a manometric probe in the gastroduodenal tract is described. It is based on hydrostatic pressure variations occurring at each recording port of a multichannel perfused probe after changes in patient's position. The data are fed into a computer and the schematic...

journal_title：Gut

authors： Bortolotti M,Bersani G

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Treatment of Helicobacter pylori infection prevents duodenal ulcer relapse. It has not been established if treatment of the infection heals duodenal ulcer. AIM:To test the hypothesis that treatment of the infection was associated with healing of duodenal ulcer. METHODS:A randomised, double blind placebo co...

journal_title：Gut

authors： Lam SK,Ching CK,Lai KC,Wong BC,Lai CL,Chan CK,Ong L

更新日期：1997-07-01 00:00:00

abstract：:Diverticulitis affects the right side of the colon more commonly than the left side in the Far East. A consecutive series of 35 patients (mean age 44 years) with right sided diverticulitis seen at this hospital is presented. All had localised pain in the right iliac fossa but systemic upset was uncommon. All but one w...

journal_title：Gut

authors： Markham NI,Li AK

更新日期：1992-04-01 00:00:00

abstract：:One-hundred-and-one normal neonates were examined manometrically in the first day of life to assess anorectal function. In order to overcome some of the difficulties in subjective interpretation of results, the stimuli used and the response pattern seen in the anal canal were measured. In the unstimulated state, all s...

journal_title：Gut

authors： Boston VE,Cywes S,Davies MR

更新日期：1977-12-01 00:00:00

abstract：:A histochemical study of conjugated and total bilirubin was made on liver biopsies of 150 patients. Three types of cholestasis were defined: type I, characterized by the presence of intracellular pigment granules in the hepatocytes; type II, showing intracellular granules and extracellular thrombi (this group may be s...

journal_title：Gut

authors： Desmet VJ,Bullens AM,De Groote J

更新日期：1970-06-01 00:00:00

abstract：:In 1964 Samman and White described 13 patients with lymphoedema of the lower extremities associated with an unusual dystrophy of the finger and toe nails: this they termed the 'yellow-nail' syndrome. Affected nails were thickened, excessively curved along both axes, very slow growing and of yellowish-grey hue; cuticle...

journal_title：Gut

authors： Duhra PM,Quigley EM,Marsh MN

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Recently identified ABCG5/8 transporters are responsible in part for the different absorption rates of campesterol, sitosterol, and cholesterol. These transporters are also expressed in the liver and might regulate biliary sterol secretion. AIMS:This study was therefore conducted to determine the biliary se...

journal_title：Gut

authors： Sudhop T,Sahin Y,Lindenthal B,Hahn C,Lüers C,Berthold HK,von Bergmann K

更新日期：2002-12-01 00:00:00

abstract：:An indicator fractionation technique using radioactive rubidium has been used to measure pancreatic blood flow after infusions of secretin, pancreozymin, urecholine, and pentagastrin. Secretin resulted in the production of a large volume of low viscous pancreatic juice and was associated with an increase in the cardia...

journal_title：Gut

authors： Goodhead B,Himal HS,Zanbilowicz J

更新日期：1970-01-01 00:00:00

abstract：:The effect of a new complex oligosaccharide exhibiting potent inhibitory action on alpha-glucoside hydrolases on intestinal absorption of sucrose in man was tested by constant in vivo perfusion of the jejunum. At concentrations of 4.65 or 15.5 X 10(-6)M the alpha-glucosidehydrolase inhibitor (alpha-GHI) markedly inhib...

journal_title：Gut

authors： Caspary WF,Kalisch H

更新日期：1979-09-01 00:00:00

abstract：:In a prospective survey positive antimitochondrial antibodies have been detected in 69/4200 (1.64%) of all sera submitted to a routine immunology laboratory. Of the 69, only nine patients had uniquivocal primary biliary cirrhosis, six others had chronic active hepatitis, 10 had abnormal liver function tests without ev...

journal_title：Gut

authors： Triger DR,Charlton CA,Ward AM

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Dyspepsia and irritable bowel syndrome are suitable conditions for assessment of quality of life. Their similarities justify the elaboration of a single specific questionnaire for the two conditions. AIMS:To examine the process leading to the validation of the psychometric properties of the functional diges...

journal_title：Gut

authors： Chassany O,Marquis P,Scherrer B,Read NW,Finger T,Bergmann JF,Fraitag B,Geneve J,Caulin C

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Gastric mucosal surface hydrophobicity (GMSH) is an essential component of the mucosal defence system that is decreased by Helicobacter pylori and non-steroidal anti-inflammatory drugs (NSAIDs). Gastric ulcers occur predominantly in elderly subjects, and may thus reflect diminished mucosal resistance. AIMS:...

journal_title：Gut

authors： Hackelsberger A,Platzer U,Nilius M,Schultze V,Günther T,Dominguez-Muñoz JE,Malfertheiner P

更新日期：1998-10-01 00:00:00

abstract：:Serum samples from 26 monozygotic twin pairs concordant or discordant with regard to inflammatory bowel disease, and rectal biopsies from 42 twins of the same subject group, were examined for IgG subclasses. They were all compared with normal controls. Almost all affected twins were in clinical remission. Paired immun...

journal_title：Gut

authors： Helgeland L,Tysk C,Järnerot G,Kett K,Lindberg E,Danielsson D,Andersen SN,Brandtzaeg P

更新日期：1992-10-01 00:00:00

abstract：:The effect of sulphasalazine and olsalazine on jejunal and ileal water and electrolyte absorption was investigated in normal subjects by a steady state intestinal perfusion of a physiological glucose bicarbonate electrolyte solution in the absence and presence of increasing concentrations of each drug. (Olsalazine 0.2...

journal_title：Gut

authors： Raimundo AH,Patil DH,Frost PG,Silk DB

更新日期：1991-03-01 00:00:00

abstract：:Faecal bile acid excretion was examined in 13 patients with adenomatous polyps of the large bowel and compared with a series of matched healthy subjects. Bile acids were analysed in detail with respect to the composition of individual bile acids and their mode of conjugation. The total excretion of bile acids by the p...

journal_title：Gut

authors： Tanida N,Hikasa Y,Shimoyama T,Setchell KD

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Concordance rates in siblings and twins provide strong evidence that genetic susceptibility is important in the pathogenesis of inflammatory bowel disease. The number and identity of susceptibility genes is largely uncertain. Cytokine genes are attractive candidate loci. AIMS:To study allelic frequencies of...

journal_title：Gut

authors： Louis E,Satsangi J,Roussomoustakaki M,Parkes M,Fanning G,Welsh K,Jewell D

更新日期：1996-11-01 00:00:00

abstract：:The effects of corticotrophin and of cortisone, methyl prednisolone, and of aldosterone on the gastric secretion of dogs have been investigated. Juice was collected from dogs with denervated pouches under basal conditions and when stimulated with meat extract and with histamine. For each secretion the volume, viscosit...

journal_title：Gut

authors： CLARKE SD,NEILL DW,WELBOURN RB

更新日期：1960-03-01 00:00:00

abstract：INTRODUCTION:Barrett's oesophageal epithelium (BE) is clinically important due to the associated inflammatory and malignant complications which are unevenly distributed throughout the BE segment. As the immunoregulatory environment may influence disease manifestations, we analysed the inflammatory and cytokine response...

journal_title：Gut

authors： Fitzgerald RC,Abdalla S,Onwuegbusi BA,Sirieix P,Saeed IT,Burnham WR,Farthing MJ

更新日期：2002-09-01 00:00:00

abstract：:A simple method based on atomic absorption spectrophotometry and using protein concentration as the reference standard was used for measuring the total tissue iron concentration in needle liver biopsy specimens from 47 patients with varying levels of body iron stores. The values obtained showed a close correlation ove...

journal_title：Gut

authors： Walker RJ,Miller JP,Dymock IW,Shilkin KB,Williams R

更新日期：1971-12-01 00:00:00

abstract：:Alkaline phosphatase has been extracted from human pancreas with n-butanol and has been shown to have distinctive isoenzyme characteristics when compared with the enzymes of small intestine and of normal serum. The enzyme has been demonstrated histochemically in a carcinoma of the pancreas and also in an islet cell tu...

journal_title：Gut

authors： Warnes TW,Timperley WR,Hine P,Kay G

更新日期：1972-07-01 00:00:00

abstract：:Octreotide has been proposed for the treatment of variceal bleeding. The effects on portal pressure, however, have been variable in published studies. As bleeding is more directly related to pressure in the varices, this study investigated the effect on variceal pressure of octreotide and terlipressin, a vasoactive dr...

journal_title：Gut

authors： Nevens F,Van Steenbergen W,Yap SH,Fevery J

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Emerging evidence suggests that highly treatment-resistant tumour-initiating cells (TICs) play a central role in the pathogenesis of pancreatic cancer. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered to be a novel anticancer agent; however, recent studies have shown th...

journal_title：Gut

authors： Kallifatidis G,Rausch V,Baumann B,Apel A,Beckermann BM,Groth A,Mattern J,Li Z,Kolb A,Moldenhauer G,Altevogt P,Wirth T,Werner J,Schemmer P,Büchler MW,Salnikov AV,Herr I

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:MicroRNA (miRNA) expression profile can be used as prognostic marker for human cancers. We aim to explore the significance of miRNAs in colorectal cancer (CRC) metastasis. DESIGN:We performed miRNA microarrays using primary CRC tissues from patients with and without metastasis, and validated selected candida...

journal_title：Gut

authors： Ling H,Pickard K,Ivan C,Isella C,Ikuo M,Mitter R,Spizzo R,Bullock M,Braicu C,Pileczki V,Vincent K,Pichler M,Stiegelbauer V,Hoefler G,Almeida MI,Hsiao A,Zhang X,Primrose J,Packham G,Liu K,Bojja K,Gafà R,Xiao L

更新日期：2016-06-01 00:00:00

abstract：:On the basis of circumstantial clinical and experimental evidence, it has been suggested that enteroglucagon (EG) may act as an enterotrophic factor. This study was undertaken to evaluate the effects of long term in vivo immunoneutralisation of EG, using monoclonal antibodies to EG, on the hyperplastic ileal response ...

journal_title：Gut

authors： Gregor M,Menge H,Stössel R,Riecken EO

更新日期：1987-01-01 00:00:00

abstract：:The effect of a long-term treatment (one to two years) with cimetidine (1.6 g per day) and an antacid (Regla pH) was evaluated in nine patients with a Barrett's oesophagus. The results showed that such long-term treatment had a beneficial effect on the symptoms and endoscopic signs of oesophagitis and on the healing o...

journal_title：Gut

authors： Wesdorp IC,Bartelsman J,Schipper ME,Tytgat GN

更新日期：1981-09-01 00:00:00

abstract：:To determine the significance of the endoscopic classification of gastritis proposed by a working party at the World Congress of Gastroenterology in Sydney 1990, 167 patients undergoing upper alimentary endoscopy were prospectively assessed by comprehensive endoscopic and histological methods. Ninety eight patients ha...

journal_title：Gut

authors： Khakoo SI,Lobo AJ,Shepherd NA,Wilkinson SP

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:Caffeine reduces toxic Ca2+ signals in pancreatic acinar cells via inhibition of inositol 1,4,5-trisphosphate receptor (IP3R)-mediated signalling, but effects of other xanthines have not been evaluated, nor effects of xanthines on experimental acute pancreatitis (AP). We have determined effects of caffeine an...

journal_title：Gut

authors： Huang W,Cane MC,Mukherjee R,Szatmary P,Zhang X,Elliott V,Ouyang Y,Chvanov M,Latawiec D,Wen L,Booth DM,Haynes AC,Petersen OH,Tepikin AV,Criddle DN,Sutton R

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate whether patients with increased or decreased gastric motility can be differentiated from healthy volunteers by means of real time magnetic resonance imaging (MRI). PATIENTS AND METHODS:Ten healthy volunteers, 10 patients with gastroparesis, and 10 patients with function...

journal_title：Gut

authors： Ajaj W,Goehde SC,Papanikolaou N,Holtmann G,Ruehm SG,Debatin JF,Lauenstein TC

更新日期：2004-09-01 00:00:00

abstract：:Rosetting techniques were used to estimate T and B cell subpopulations in the peripheral blood in patients with treated and untreated adult coeliac disease and in control subjects. In patients with untreated coeliac disease, T cell numbers were significantly lower than in controls or treated patients, although there w...

journal_title：Gut

authors： Bullen AW,Losowsky MS

更新日期：1978-10-01 00:00:00