Abstract:
:The effect of a long-term treatment (one to two years) with cimetidine (1.6 g per day) and an antacid (Regla pH) was evaluated in nine patients with a Barrett's oesophagus. The results showed that such long-term treatment had a beneficial effect on the symptoms and endoscopic signs of oesophagitis and on the healing of a Barrett's ulcer, but did not result in a regression of the squamocolumnar junction back towards the cardia. No significant changes were observed in the histological epithelial types in the biopsies taken below the squamocolumnar junction. No clinical or biochemical side-effects or changes in biochemical parameters were noted during this study.
journal_name
Gutjournal_title
Gutauthors
Wesdorp IC,Bartelsman J,Schipper ME,Tytgat GNdoi
10.1136/gut.22.9.724subject
Has Abstractpub_date
1981-09-01 00:00:00pages
724-7issue
9eissn
0017-5749issn
1468-3288journal_volume
22pub_type
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