Preparation of lymphoid cells from small specimens of human gastrointestinal mucosa.

abstract：:The aim of this study is to assess the value of jejunal manometry in the diagnosis of subacute mechanical obstruction distal to the proximal small bowel. In a retrospective review of 850 manometric tracings carried out in patients with unexplained nausea, vomiting, abdominal pain or altered bowel movements, 16 tracing...

journal_title：Gut

authors： Camilleri M

更新日期：1989-04-01 00:00:00

abstract：:We have reviewed the outcome of all patients undergoing their first intestinal resection for Crohn's disease at this hospital between 1970 and 1987. Recurrence rates, defined by recurrent intestinal symptoms and radiological confirmation of mucosal disease, were calculated using survival analysis. Age, sex, anatomical...

journal_title：Gut

authors： Griffiths AM,Wesson DE,Shandling B,Corey M,Sherman PM

更新日期：1991-05-01 00:00:00

abstract：:Faecal chymotrypsin was measured in patients with chronic pancreatitis and in healthy black urban and rural control subjects. In the patients, significantly lower values of faecal chymotrypsin were obtained (mean (SD) 2.4 1.79 U/g stool) whereas in urban control subjects, values were within the normal range (mean (SD)...

journal_title：Gut

authors： Riedel L,Walker AR,Segal I,Mohamed AE,Smyth AE,Daya B,Naik I

更新日期：1991-03-01 00:00:00

abstract：:Clinical data and histology from the oesophagus, gastric antrum, and duodenum were collected from 36 patients undergoing surgery for duodenal ulcer. Gastritis was present in 94% of the patients (25% of atrophic type), oesophagitis in 72% and duodenitis in 39%. Abnormal biopsies were present from all three sites in 33%...

journal_title：Gut

authors： Earlam RJ,Amerigo J,Kakavoulis T,Pollock DJ

更新日期：1985-01-01 00:00:00

abstract：:The major end products of fermentation, short chain fatty acids (acetate, propionate, butyrate) were measured in portal and peripheral venous blood after the caecal instillation of lactulose at surgery in patients undergoing elective cholecystectomy. Blood samples for short chain fatty acid measurement were taken befo...

journal_title：Gut

authors： Peters SG,Pomare EW,Fisher CA

更新日期：1992-09-01 00:00:00

abstract：:Two West Indian patients with Kveim-biopsy proven sarcoidosis developed chronic cholestatic liver disease, clinically and biochemically similar to primary biliary cirrhosis. Liver histology revealed multiple granulomas with reduction in bile ducts and, in one patient, progression to biliary cirrhosis. Portal hypertens...

journal_title：Gut

authors： Bass NM,Burroughs AK,Scheuer PJ,James DG,Sherlock S

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:The prevalence of portopulmonary hypertension (PPHTN) in patients with cirrhosis and refractory ascites is unknown. Its presence may preclude patients from receiving a transjugular intrahepatic portosystemic shunt or liver transplantation as a definitive treatment for their end stage cirrhosis. PURPOSE:To d...

journal_title：Gut

authors： Benjaminov FS,Prentice M,Sniderman KW,Siu S,Liu P,Wong F

更新日期：2003-09-01 00:00:00

abstract：:The generation of suppression by concanavalin A in peripheral blood mononuclear cells in treated and untreated coeliac subjects using an in vitro assay was found to be significantly increased when compared with controls. The response of peripheral blood mononuclear cells to the plant mitogen concanavalin A (con A) was...

journal_title：Gut

authors： O'Farrelly C,McKeever U,Feighery C,Weir DG

更新日期：1984-06-01 00:00:00

abstract：:Intravenous cholangiograms were performed on 100 unselected nonicteric patients using methylglucamine ioglycamide (Biligram). Fifty patients received 10.5 g of contrast medium and 50 received 5.25 g of medium. The contrast medium was injected evenly over five minutes. Side effects were recorded in only 13% of patients...

journal_title：Gut

authors： Parkin GJ,Herlinger H

更新日期：1974-04-01 00:00:00

abstract：:To investigate the basis of subclinical alveolitis in patients with primary biliary cirrhosis, 10 primary biliary cirrhosis patients were studied by bronchoalveolar lavage. Both bronchoalveolar lavage lymphoid and non-lymphoid cell populations were analysed using immunocytological methods to determine their proportion...

journal_title：Gut

authors： Spiteri MA,Johnson M,Epstein O,Sherlock S,Clarke SW,Poulter LW

更新日期：1990-02-01 00:00:00

abstract：:Ileal disease or resection causes bile salt malabsorption and a reduction in the bile salt content of bile. Since cholesterol solubility requires adequate bile salt concentrations, depletion of the bile salt content of bile might, therefore, jeopardize cholesterol solubility and predispose to cholesterol gallstone for...

journal_title：Gut

authors： Dowling RH,Bell GD,White J

更新日期：1972-06-01 00:00:00

abstract：AIM:The aim of this study was to implement an imaging protocol for positron emission tomography/computed tomography (PET/CT) colonography and to combine this protocol with whole body PET/CT tumour staging for a single whole body examination for routine clinical use. SUBJECTS AND METHODS:A whole body PET/CT protocol fo...

journal_title：Gut

authors： Veit P,Kühle C,Beyer T,Kuehl H,Herborn CU,Börsch G,Stergar H,Barkhausen J,Bockisch A,Antoch G

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:HCV is a major cause of chronic liver disease worldwide, but the role of neutralising antibodies (nAbs) in its natural history remains poorly defined. We analysed the in vivo role of hypervariable region 1 (HVR1) for HCV virion properties, including nAb susceptibility. DESIGN:Analysis of HCV from human liver...

journal_title：Gut

authors： Prentoe J,Verhoye L,Velázquez Moctezuma R,Buysschaert C,Farhoudi A,Wang R,Alter H,Meuleman P,Bukh J

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND/AIMS:Transjugular intrahepatic portosystemic stent shunt (TIPSS) is effective in the prevention of variceal rebleeding but requires invasive portographic follow up. This randomised controlled trial aims to test the hypothesis that combining variceal band ligation (VBL) with TIPSS can obviate the need for lon...

journal_title：Gut

authors： Tripathi D,Lui HF,Helmy A,Dabos K,Forrest E,Stanley AJ,Jalan R,Redhead DN,Hayes PC

更新日期：2004-03-01 00:00:00

abstract：:A case is described of primary biliary cirrhosis in a 59 year old woman who initially presented with a rash over her lower legs 18 months before diagnosis. Skin biopsy examination showed non-caseating granulomas of the sarcoid type. It is believed that this is the first reported case of primary biliary cirrhosis prese...

journal_title：Gut

authors： Jardine DL,Chambers ST,Hart DJ,Chapman BA

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of daclatasvir, an HCV NS5A inhibitor with pangenotypic activity, administered with peginterferon-alfa-2a/ribavirin. DESIGN:In this Phase 2b double-blind, placebo-controlled study, treatment-naive adults with HCV genotype 1 (N=365) or 4 (N=30) infection were randomly assig...

journal_title：Gut

authors： Hézode C,Hirschfield GM,Ghesquiere W,Sievert W,Rodriguez-Torres M,Shafran SD,Thuluvath PJ,Tatum HA,Waked I,Esmat G,Lawitz EJ,Rustgi VK,Pol S,Weis N,Pockros PJ,Bourlière M,Serfaty L,Vierling JM,Fried MW,Weiland O,B

更新日期：2015-06-01 00:00:00

abstract：:The two major forms of inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), are chronic immune-mediated conditions characterised by an increased production of pro-inflammatory cytokines that act as critical drivers of intestinal inflammation. Anti-cytokine therapy has been s...

journal_title：Gut

authors： Danese S,Argollo M,Le Berre C,Peyrin-Biroulet L

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Enterochromaffin cell-derived serotonin (5-HT) promotes intestinal inflammation. We tested hypotheses that peripheral tryptophan hydroxylase (TPH) inhibitors, administered orally, block 5-HT biosynthesis and deplete 5-HT from enterochromaffin cells sufficiently to ameliorate intestinal inflammation; moreover,...

journal_title：Gut

authors： Margolis KG,Stevanovic K,Li Z,Yang QM,Oravecz T,Zambrowicz B,Jhaver KG,Diacou A,Gershon MD

更新日期：2014-06-01 00:00:00

abstract：:The cholesteryl-14C-octanoate breath test was used to monitor the intraluminal enzymatic activity of pancreatin preparations in six patients with severe pancreatic insufficiency. Conventional enzyme replacement, with cimetidine as an adjunct, was compared to supplementation with enteric coated microspheres. In healthy...

journal_title：Gut

authors： Mundlos S,Kühnelt P,Adler G

更新日期：1990-11-01 00:00:00

abstract：:A group of 80 patients with diseases of the small intestine were given a standardized psychiatric assessment every time they attended the outpatients' department over a period of a year. Forty-six patients with idiopathic steatorrhoea, 23 patients with Crohn's disease, and 11 patients with alactasia were interviewed o...

journal_title：Gut

authors： Goldberg D

更新日期：1970-06-01 00:00:00

abstract：:The effect of purified toxin A and partially purified toxin B on rabbit ileum and colon was investigated. Toxin A caused tissue damage which was followed by permeability changes and fluid accumulation in both tissues. Toxin A did not increase the permeability of the colon to the extent observed for ileum; secreted flu...

journal_title：Gut

authors： Mitchell TJ,Ketley JM,Haslam SC,Stephen J,Burdon DW,Candy DC,Daniel R

更新日期：1986-01-01 00:00:00

abstract：:Blood ethanol concentrations after separate oral dosing and intravenous infusion of ethanol (0.15 g/kg) were measured in 16 control subjects and 13 subjects treated with ranitidine. All subjects underwent routine upper gastrointestinal endoscopy. Peak blood ethanol concentrations, and area under the blood ethanol/time...

journal_title：Gut

authors： Brown AS,Fiaterone JR,Day CP,Bennett MK,Kelly PJ,James OF

更新日期：1995-09-01 00:00:00

abstract：:Eighteen patients with achalasia of the cardia diagnosed by radiography, endoscopy, and manometry were subjected to forced pneumatic dilatation under fluoroscopic control. The procedure was uneventful in all but one patient who developed a pneumomediastinum which resolved on conservative management. A satisfactory res...

journal_title：Gut

authors： Lishman AH,Dellipiani AW

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVE:A high body mass index (BMI) is associated with an increased risk for severe liver disease. It is unclear if this risk differs across BMI categories, and if the association is partially attributed to development of type 2 diabetes mellitus (T2DM). DESIGN:We used register data from more than 1.2 million Swedi...

journal_title：Gut

authors： Hagström H,Tynelius P,Rasmussen F

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase 2 (COX-2) and matrix metalloproteinases (MMPs) have been implicated in tissue injury and fibrogenesis in animal models but little is known regarding their role in hepatitis C virus (HCV) related liver disease in humans. AIMS:To characterise the intrahepatic expression pattern of COX-2 and MMP...

journal_title：Gut

authors： Núñez O,Fernández-Martínez A,Majano PL,Apolinario A,Gómez-Gonzalo M,Benedicto I,López-Cabrera M,Boscá L,Clemente G,García-Monzón C,Martín-Sanz P

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Visceral hyperalgesia has been implicated as a factor contributing to symptom generation in irritable bowel syndrome (IBS). However, previous studies using intestinal balloon distension have used psychophysical procedures which do not provide adequate and unbiased measures of visceral sensitivity. METHODS:T...

journal_title：Gut

authors： Naliboff BD,Munakata J,Fullerton S,Gracely RH,Kodner A,Harraf F,Mayer EA

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:In this consensus statement, an international panel of experts deliver their opinions on key questions regarding the contribution of the human microbiome to carcinogenesis. DESIGN:International experts in oncology and/or microbiome research were approached by personal communication to form a panel. A structu...

journal_title：Gut

authors： Scott AJ,Alexander JL,Merrifield CA,Cunningham D,Jobin C,Brown R,Alverdy J,O'Keefe SJ,Gaskins HR,Teare J,Yu J,Hughes DJ,Verstraelen H,Burton J,O'Toole PW,Rosenberg DW,Marchesi JR,Kinross JM

更新日期：2019-09-01 00:00:00

abstract：:The cause of a biliary tract stricture may be difficult to determine radiologically. Exfoliative biliary cytology was evaluated in 62 patients (median age 65 years, range 30-94) with biliary tract strictures presenting to the Hepatobiliary Unit between January 1984 and December 1989. Bile samples were taken during end...

journal_title：Gut

authors： Davidson B,Varsamidakis N,Dooley J,Deery A,Dick R,Kurzawinski T,Hobbs K

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The effectiveness of surveillance for hepatocellular carcinoma (HCC) in the USA is largely unknown. The objective of this study was to evaluate the effectiveness of HCC surveillance in a national Veterans Administration (VA) practice setting, using the national VA hepatitis C virus (HCV) Clinical Ca...

journal_title：Gut

authors： El-Serag HB,Kramer JR,Chen GJ,Duan Z,Richardson PA,Davila JA

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND/AIMS:Studies in animals suggest a physiological role for glucagon-like peptide-1-(7-36)-amide (GLP-1) in regulating satiety. The role of GLP-1 in regulating food intake in man has, however, not been investigated. Subjects-Sixteen healthy male subjects were examined in a double blind placebo controlled fashio...

journal_title：Gut

authors： Gutzwiller JP,Göke B,Drewe J,Hildebrand P,Ketterer S,Handschin D,Winterhalder R,Conen D,Beglinger C

更新日期：1999-01-01 00:00:00