Abstract:
:The effect of purified toxin A and partially purified toxin B on rabbit ileum and colon was investigated. Toxin A caused tissue damage which was followed by permeability changes and fluid accumulation in both tissues. Toxin A did not increase the permeability of the colon to the extent observed for ileum; secreted fluid contained less protein of plasma origin. Toxin B had no effect on either tissue. Secretory and tissue damaging properties of crude C difficile toxins were found to be due to toxin A.
journal_name
Gutjournal_title
Gutauthors
Mitchell TJ,Ketley JM,Haslam SC,Stephen J,Burdon DW,Candy DC,Daniel Rdoi
10.1136/gut.27.1.78subject
Has Abstractpub_date
1986-01-01 00:00:00pages
78-85issue
1eissn
0017-5749issn
1468-3288journal_volume
27pub_type
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